Iddm21 QTL Report (Rattus norvegicus)

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QTL Registration

General

QTL: Iddm21 (Insulin dependent diabetes mellitus QTL 21) Rattus norvegicus
Symbol:	Iddm21
Name:	Insulin dependent diabetes mellitus QTL 21
RGD ID:	1578775
Trait:	blood glucose amount (VT:0000188)
Measurement Type:	blood glucose level (CMO:0000046)
LOD Score:	4.13
P Value:	Not Available
Variance:	Not Available
Position	No map positions available.
Cross Type:	Not Available
Strains Crossed:	LEW.1AR1-iddm/Ztm BN/Ztm

Annotation Click to see Annotation Detail View

Candidate Gene Status

	Ins1 is a candidate Gene for Iddm21
	Nkx2-3 is a candidate Gene for Iddm21

Disease Annotations Click to see Annotation Detail View

hyperglycemia (IAGP)

type 1 diabetes mellitus (IAGP,IDA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal pancreatic islet morphology (IAGP)

hyperglycemia (IAGP)

increased susceptibility to autoimmune disorder (IAGP)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

blood glucose level (IDA)

Experimental Condition

control condition (IDA)

Measurement Method

blood glucose test strip read by electrochemical glucometer (IDA)

Vertebrate Trait

blood glucose amount (IDA)

Rat Strain

BN/Ztm (IEA)

LEW.1AR1-iddm/Ztm (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus.	Weiss H, etal., Mamm Genome 2005 Jun;16(6):432-41.

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Flank 1: (D1Rat496)

Rat Assembly	Chr	Position (strand)	Source
SHRSP x BN Map	1	133.48	UniSTS
SHRSP x BN Map	1	133.48	RGD

Additional Information

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Iddm21 (Insulin dependent diabetes mellitus QTL 21) Rattus norvegicus

Mammalian Phenotype