Tspe1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Tspe1 (Trichinella spiralis expulsion QTL 1) Rattus norvegicus

Symbol: Tspe1
Name: Trichinella spiralis expulsion QTL 1
RGD ID: 1578659
Previously known as: Tspe; Trichinella spiralis expulsion locus
Trait: parasite quantity   (VT:0010441)    
Measurement Type: logarithm of the intestinal adult Trichinella spiralis count   (CMO:0002024)    
LOD Score: 4.8
P Value: Not Available
Variance: 11.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,381,434 - 65,691,299RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0966,757,444 - 71,010,122RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0966,570,118 - 71,564,273RGDRnor5.0
RGSC_v3.4958,516,719 - 62,957,638RGDRGSC3.4
RGSC_v3.1958,663,702 - 63,104,620RGD
Cross Type: Not Available
Strains Crossed: DA/Slc F344/NSlc 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Cd28 is a candidate Gene for Tspe1
Icos is a candidate Gene for Tspe1

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
DA/Slc  (IEA)
F344/NSlc  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Chromosomal mapping of host resistance loci to Trichinella spiralis nematode infection in rats. Suzuki T, etal., Immunogenetics. 2006 Feb 8;:1-5.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1307676Fam117bfamily with sequence similarity 117, member B96134028461418531Rat
41278460LOC120094801uncharacterized LOC12009480196139447061398897Rat
735110Ica1lislet cell autoantigen 1-like96141095961469884Rat
735072Wdr12WD repeat domain 1296147549861502762Rat
1306822Carfcalcium responsive transcription factor96150236861552433Rat
1594799Nbeal1neurobeachin-like 196157515461743896Rat
41335151Atp5mc2-ps1ATP synthase membrane subunit c locus 2, pseudogene 196174626061746688Rat
735221Cyp20a1cytochrome P450, family 20, subfamily a, polypeptide 196175580461805123Rat
628771Abi2abl-interactor 296182718661905703Rat
1308387Raph1Ras association (RalGDS/AF-6) and pleckstrin homology domains 196190747661990170Rat
7736852LOC102547711uncharacterized LOC10254771196204614362050985Rat
41364019LOC120094895small nucleolar RNA SNORA5196209395062094058Rat
41235983LOC120094692uncharacterized LOC12009469296214346762149952Rat
2299Cd28Cd28 molecule96216632462194674Rat
61975Ctla4cytotoxic T-lymphocyte-associated protein 496231887462325978Rat
620123Icosinducible T-cell co-stimulator96236807562406900Rat
1590313Psma7-ps3proteasome 20S subunit alpha 7, pseudogene 396241270962415587Rat
11385622LOC108351940uncharacterized LOC10835194096244344262466139Rat
7595922LOC102548093uncharacterized LOC10254809396275091462757597Rat
1593480Paics-ps7phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase, pseudogene 796290127462922952Rat
1584992Pard3bpar-3 family cell polarity regulator beta96303843564067178Rat
621442Nrp2neuropilin 296412281564238007Rat
7626358LOC102548410uncharacterized LOC10254841096438316264410799Rat
2321317Rpl37-ps5ribosomal protein L37, pseudogene 596441747564417847Rat
41384701LOC120094933small nucleolar RNA SNORA1796443688164436969Rat
1304808Ino80dINO80 complex subunit D96444707564514013Rat
7594970Nop16-ps2NOP16 nucleolar protein, pseudogene 296453634964546088Rat
1359670Ndufs1NADH:ubiquinone oxidoreductase core subunit S196454643064579751Rat
1311415Eef1b2eukaryotic translation elongation factor 1 beta 296458016364582737Rat
40960633Snord51small nucleolar RNA, C/D box 5196458173164581808Rat
41148168Snora41small nucleolar RNA, H/ACA box 4196458207064582201Rat
2728Cmklr2chemerin chemokine-like receptor 296458331064617883Rat
1560005Zdbf2zinc finger, DBF-type containing 296467297464748446Rat
2321064Cox5b-ps1cytochrome c oxidase subunit 5B, pseudogene 196479269464793077Rat
1305739Adam23ADAM metallopeptidase domain 2396486264965009718Rat
9235481Fam237afamily with sequence similarity 237 member A96502431265035051Rat
2320917Dytndystrotelin96503737865098549Rat
1307874Mdh1bmalate dehydrogenase 1B96512037065168008Rat
11476915LOC108351941dnaJ homolog subfamily A member 1 pseudogene96516520265166696Rat
1307883Fastkd2FAST kinase domains 296516614865188184Rat
11454381LOC108351943uncharacterized LOC10835194396522571165235289Rat
1588771Cpocarboxypeptidase O96531999665338250Rat
40959969LOC120094803Kruppel like factor 796543368365526372Rat
1306029Klf7KLF transcription factor 796543368365526372Rat
9211165LOC103690543uncharacterized LOC10369054396557369165585909Rat
41094824LOC120094693uncharacterized LOC12009469396559217365596677Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
36147D9Rat1514596538378965383934Ratregion
35172D9Rat1912596228760862287724Ratregion
37094D9Rat15620196411687264117084Ratregion
34771D9Rat1817596246215362462332Ratregion
34815D9Rat1617596138143461381613Ratregion
35843D9Rat1312796569118865691299Ratregion
38066D9Rat6520496450779964507997Ratregion
41514D9Rat11715596346956963469726Ratregion
41554D9Rat11616796432949264329651Ratregion
44610D9Got6420696422914764229355Ratregion
44611D9Got6722396324139963241622Ratregion
44612D9Got6619996313226163132460Ratregion
44614D9Got6916096449669764496857Ratregion
44615D9Got6520296426994164270143Ratregion
44616D9Got6811896542110465421222Ratregion
45516D17Got10816296290804662908187Ratregion
62512D9Uia218396487016764870352Ratregion
62513D9Uia313896441130964411447Ratregion
62516D9Uia428196207227562072556Ratregion
66433D9Mco820096435632364356550Ratregion
67302D9Arb215696526294565263101Ratregion
1627002D9Mco522596435636664356591Ratregion
1627488D9Mco322496435636664356590Ratregion
1640764D9Got23829796443847564438771Ratregion
1640764D9Got23829796443847564438796Ratregion
7206016Nrp26796413894664139013Ratregion
5036201D1Mit46621796510606865106285Ratregion
7206512UniSTS:54680092796458562264586549Ratregion
5028975RH14303617896147982261480001Ratregion
5026666RH13307621196140870561408916Ratregion
5032241AI83986710596190550561905610Ratregion
5030085BE09815715096191001661910166Ratregion
5030811BE12029919596533084865331043Ratregion
5031093BF40611320396499754364997746Ratregion
5031101BF40620924796420431864204564Ratregion
5031183BF41380910696142598461426090Ratregion
5054971RH14353116296500634365006505Ratregion
5051246RH13452319296190537861905570Ratregion
5053631RH14276018896155126361551451Ratregion
5059538BE09723015896421915964219317Ratregion
5055897RH14406617496533802065338194Ratregion
5056209RH14424615096329520263295352Ratregion
5050000RH13380422096141372061413940Ratregion
5051789RH9465918596219159662191782Ratregion
5050962RH13435921396454641264546625Ratregion
5047734RH13249821996147559361475812Ratregion
5047928RH13261020796518693265188085Ratregion
5049720RH13364319896309597663096174Ratregion
5042968RH12975218296240660762406789Ratregion
5042832RH12967119196405604164056232Ratregion
5075644RH13871323996190328361903522Ratregion
5074346RH13796420896139712261397330Ratregion
5076134RH13899912696445340864453534Ratregion
5076242RH13906221096190842361908633Ratregion
5075704RH13874813296190185061901982Ratregion
5077096RH13955820696500946965009675Ratregion
5070588RH13458819496474794764748141Ratregion
5068134AU04732714296333323163333373Ratregion
5063618BE10785719396139017361390366Ratregion
5062192BF39754921096423547264235682Ratregion
5064050BE12055915796452628964526446Ratregion
5064156BE12068717296380167363801845Ratregion
5062834BI29510320196240633462406536Ratregion
5062910AA95553320696423769264237898Ratregion
5066118BF41344121096451457464514886Ratregion
5066410AU04837317696231536862315544Ratregion
5061352BF39629115396421102964211182Ratregion
5064916BF39991815996191208961912248Ratregion
5087189BE11729316896189491861895086Ratregion
5089499AU04919213596150788361508018Ratregion
5084788AI22920419996543925465439453Ratregion
5085008AA89139617896454250564542683Ratregion
5084668AI1778939996444734364447442Ratregion
5084952AI41184114496174352461743668Ratregion
5083021BF39067515296406661564066767Ratregion
5081402AI50121318496500734265007526Ratregion
5081533BE11720316696543597665436142Ratregion
5083449BE10003720796173795461738161Ratregion
5083735AI23773711296199639861996510Ratregion
5503230UniSTS:237290096148087461481369Ratregion
5506111UniSTS:49839616396423779864237961Ratregion
5501960MARC_21133-21134:1025201105:194196375744463758385Ratregion
6903892D9Mco10723096152910161529521Ratregion
6903892D9Mco10723096152929161529521Ratregion
Position Markers

Flank 1: (D9Rat16)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2961,381,434 - 61,381,613 (+)MAPPER
Rnor_6.0966,757,444 - 66,757,620NCBI
Rnor_5.0966,570,118 - 66,570,294UniSTS
RGSC_v3.4958,516,720 - 58,516,896UniSTS
RGSC_v3.4958,516,719 - 58,516,896RGD
RGSC_v3.1958,663,702 - 58,663,878RGD
Celera958,815,886 - 58,816,062UniSTS
RH 3.4 Map9495.2RGD
RH 3.4 Map9495.2UniSTS
RH 2.0 Map9574.9RGD
SHRSP x BN Map942.2298RGD
Cytogenetic Map9q31UniSTS
Peak: (D9Rat19)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2962,287,608 - 62,287,724 (+)MAPPER
Rnor_6.0967,667,690 - 67,667,805NCBI
Rnor_5.0967,478,940 - 67,479,055UniSTS
RGSC_v3.4959,463,565 - 59,463,680UniSTS
RGSC_v3.4959,463,564 - 59,463,680RGD
RGSC_v3.1959,610,547 - 59,610,662RGD
Celera959,710,405 - 59,710,520UniSTS
RH 3.4 Map9501.0RGD
RH 3.4 Map9501.0UniSTS
RH 2.0 Map9575.1RGD
SHRSP x BN Map942.1898RGD
Flank 2: (D9Rat13)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2965,691,188 - 65,691,299 (+)MAPPER
Rnor_6.0971,010,012 - 71,010,122NCBI
Rnor_5.0971,564,163 - 71,564,273UniSTS
RGSC_v3.4962,957,527 - 62,957,638RGD
RGSC_v3.4962,957,528 - 62,957,638UniSTS
RGSC_v3.1963,104,510 - 63,104,620RGD
Celera963,101,024 - 63,101,134UniSTS
RH 3.4 Map9538.9UniSTS
RH 3.4 Map9538.9RGD
RH 2.0 Map9606.1RGD
SHRSP x BN Map945.5498RGD
FHH x ACI Map942.32RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96138143465691299Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general DA/Slc allele is associated with strong host response and expulsion of intestinal Trichinella spiralis nematodes 1578305