Schws2 QTL Report (Rattus norvegicus) - Rat Genome Database

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Pathways

QTL: Schws2 (Schwannoma susceptibility QTL 2) Rattus norvegicus

Symbol: Schws2
Name: Schwannoma susceptibility QTL 2
RGD ID: 1576310
Previously known as: Mediating schwannoma susceptibility QTL 2; Mss2
Trait: nervous system integrity trait   (VT:0010566)    
Measurement Type: percentage of study population developing trigeminal nerve neurilemmomas during a period of time   (CMO:0002017)    
LOD Score: Not Available
P Value: 0.029
Variance: Not Available
Position No map positions available.
Cross Type: Not Available
Strains Crossed: BDIV/Zte BDIX/Zte 



Disease Annotations     Click to see Annotation Detail View
neurilemmoma  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BDIV/Zte  (IEA)
BDIX/Zte  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Gender-specific polygenic control of ethylnitrosourea-induced oncogenesis in the rat peripheral nervous system. Koelsch BU, etal., Int J Cancer. 2006 Jan 1;118(1):108-14.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D1Mit4)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map11322.4UniSTS
RH 3.4 Map11322.4RGD
RH 2.0 Map1852.2RGD
Cytogenetic Map1 RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_statistics_details logistic regression model for analysis of schwannoma incidence (dichotomous), Cox regression model for analysis of survival times (quantitative);significant p-values obtained for all animals, tumor incidence and survival time; males tumor incidence, survival time 1559300