Bw57 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bw57 (Body weight QTL 57) Rattus norvegicus

Symbol: Bw57
Name: Body weight QTL 57
RGD ID: 1558652
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: 4.2
P Value: 8.0E-4
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,327,017 - 90,930,437RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01094,170,766 - 112,626,471RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01092,325,331 - 93,965,127RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41093,730,129 - 95,381,455RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.11095,375,707 - 110,733,352RGD
Cross Type: Not Available
Strains Crossed: SHRSP/Tkyo WKY/Tkyo 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
body weight  (IDA)

Experimental Condition

Measurement Method

Vertebrate Trait
body mass  (IDA)

Rat Strain
SHRSP/Tkyo  (IEA)
WKY/Tkyo  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Identification of quantitative trait loci for cardiac hypertrophy in two different strains of the spontaneously hypertensive rat. Inomata H, etal., Hypertens Res 2005 Mar;28(3):273-81.
2. Identification of genetic loci involved in diabetes using a rat model of depression. Solberg Woods LC, etal., Mamm Genome. 2009 Aug 22.
Related QTLs

Related QTL Description Reference
Cm44 maps to same region RGD:1554311
Bw87 maps to same region RGD:2312611


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1311429Kansl1KAT8 regulatory NSL complex subunit 1108923766789368735Rat
1304921Cdc27cell division cycle 27108940072089449816Rat
1591197Myl4myosin, light chain 4108944945689485365Rat
1591196Gstp1-ps2glutathione S-transferase pi 1, pseudogene 2108949816989499906Rat
628868Itgb3integrin subunit beta 3108950991789564679Rat
1305423Efcab3EF-hand calcium binding domain 3108958352690077260Rat
11381204LOC108352141uncharacterized LOC108352141108988662589887932Rat
41249496LOC120095378U6 spliceosomal RNA109003343690033542Rat
1310240Mettl2methyltransferase like 2109009552790109354Rat
1590899Cactin-ps2cactin, spliceosome C complex subunit, pseudogene 2109014221190155347Rat
1310907Tlk2tousled-like kinase 2109015444990248562Rat
41034882LOC120095467U6atac minor spliceosomal RNA109022333990223431Rat
41101625Cycs-ps6cytochrome c, somatic, pseudogene 6109022735690227705Rat
1559436Mrc2mannose receptor, C type 2109026198690323187Rat
41318785LOC120095186uncharacterized LOC120095186109026236690267267Rat
41334181LOC120095187uncharacterized LOC120095187109028417790289455Rat
1311692Marchf10membrane associated ring-CH-type finger 10109033278390423109Rat
40927017LOC120095189uncharacterized LOC120095189109034159690366478Rat
11389364LOC108352144uncharacterized LOC108352144109042062290461890Rat
40973775Trnav-aac25transfer RNA valine (anticodon AAC) 25109054823190548311Rat
1309285Tanc2tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2109055312490873477Rat
41337284LOC120095493U4 spliceosomal RNA109056480690564957Rat
41292971LOC120095191uncharacterized LOC120095191109065984090687446Rat
41135105LOC120095351U6 spliceosomal RNA109074981890749924Rat
9215295Snupn-ps1snurportin 1, pseudogene 1109081068190821759Rat
1310987Cyb561cytochrome b-561109087805290888734Rat
2493Aceangiotensin I converting enzyme109091031690930437Rat
41378188LOC120095193uncharacterized LOC120095193109091905390920018Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
37150D10Rat204216109040439790404618Ratregion
34896D10Rat17172109062743990627625Ratregion
39410D10Rat140211108953494589535132Ratregion
44817D10Got140183109035578190355964Ratregion
44821D10Got141160109062750790627669Ratregion
44822D10Got139166109048805390488219Ratregion
59970D10Got137141109026279290262933Ratregion
67318D10Arb12109012861890128836Ratregion
1630302D10Got134175108989096889891143Ratregion
1579122D10Chm237208108958722389587433Ratregion
5035090SHGC-57386160109024841290248572Ratregion
5030613BF398330225109027725490277479Ratregion
5028141D11Mit58259108947526989475528Ratregion
5028533AI452358176108940111889401294Ratregion
5053549RH142713137108935418689354323Ratregion
5051977RH94768116109093032190930437Ratregion
5059456AW530915165108970204389702208Ratregion
5059456AW530915165108970204389702208Ratregion
5054863RH143468169109033570790335877Ratregion
5055179RH143651177109057256390572740Ratregion
5056869RH144627151108956494389565094Ratregion
5040190RH128141198109010993090110128Ratregion
5041518RH1289030109028923690289418Ratregion
5075076RH138384150109024020290240352Ratregion
5076224RH139051177109073819990738376Ratregion
5079918RH141278182109024283590243017Ratregion
5079280RH140890220108940127989401499Ratregion
5071142RH134911219109086850790868726Ratregion
5078644RH140464177109032284690323023Ratregion
5078854RH140590188109033284390333031Ratregion
5073802RH137647207109088939290889599Ratregion
5067190AU047906157109031158990311746Ratregion
5062080BI29490595109011349890113593Ratregion
5065190BE121110201109033461590334816Ratregion
5064024AA956078148109087320490873352Ratregion
5065848AI045565184108940339489403578Ratregion
5062688BF403857161109014257390142734Ratregion
5064582BF399386151109076378890763939Ratregion
5061528BF396623154109026082990260983Ratregion
5082131BF409851155109090761990907774Ratregion
5089821AU049383192109052953990529731Ratregion
5090823AU049984154109031161090311759Ratregion
5081913BE118743151109080909090809241Ratregion
5081184RH142013216109037542690375642Ratregion
5503718TLK2_8170902109024754190248443Ratregion
5500693RH47409139109024829890248437Ratregion
Position Markers

Flank 1: (Ace)
Rat AssemblyChrPosition (strand)Source
GRCr81091,410,129 - 91,430,246 (+)NCBI
mRatBN7.21090,910,316 - 90,930,437 (+)NCBI
mRatBN7.2 Ensembl1090,910,316 - 90,931,131 (+)Ensembl
UTH_Rnor_SHR_Utx1095,964,627 - 95,984,783 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01095,427,801 - 95,447,951 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01090,839,016 - 90,859,102 (+)NCBI
Rnor_6.01094,170,766 - 94,213,831 (+)NCBI
Rnor_6.0 Ensembl1094,170,766 - 94,187,822 (+)Ensembl
Rnor_5.01093,922,062 - 93,965,127 (+)NCBI
RGSC_v3.41095,361,338 - 95,381,455 (+)NCBI
Celera1089,588,544 - 89,608,666 (+)NCBI
Cytogenetic Map10q32.1NCBI
Peak: (D10Arb12)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21090,128,618 - 90,128,836NCBI
Rnor_5.01093,145,109 - 93,145,350NCBI
RGSC_v3.41094,555,672 - 94,555,912RGD
Cytogenetic Map10 RGD
Flank 2: (D10Mgh1)
Rat AssemblyChrPosition (strand)Source
Celera10102,748,696 - 102,748,839UniSTS
RH 2.0 Map101407.7RGD
Cytogenetic Map10 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312662Slep8Serum leptin concentration QTL 80.05blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1057134272102134272Rat
2312668Scl65Serum cholesterol level QTL 650.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1057134272102134272Rat
2312672Insul15Insulin level QTL 150.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1057134272102134272Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106134527698211570Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)1066978955107211142Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)1082685200107211142Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108256485692369470Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)106134527699703528Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1080515287101325465Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070199100107211142Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)105177461295600334Rat
631538Oia5Oil induced arthritis QTL 5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087055121107211142Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104736947092369470Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108051528791230079Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1088539139107211142Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)107877551698279596Rat
1300137Bp186Blood pressure QTL 1863.57arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1090627439107057807Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076452683107211142Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105480929299809292Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)105177294096772940Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)106134527699703528Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1057576521102576521Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107437208494965338Rat
1579915Bp280Blood pressure QTL 2800.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090404397107211142Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087307617107211142Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068420376107211142Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1076246085107211142Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107345313696120911Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105379749498952626Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1053797385107211142Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1072224939107211142Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104502965095600334Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)108402232193995963Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107255241693995749Rat
724530Bp149Blood pressure QTL 1490.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1090627439107211142Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)108730761796121100Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062057807107057807Rat
1642980Bp300Blood pressure QTL 300arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068383129107211142Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106674365598003205Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072224939107211142Rat
4889492Pancm2Pancreatic morphology QTL 23.2pancreatic beta cell morphology trait (VT:0005217)ratio of insulin-positive cell area to total area of splenic region of pancreas (CMO:0001814)1076748906107211142Rat
1558652Bw57Body weight QTL 574.20.0008body mass (VT:0001259)body weight (CMO:0000012)108932701790930437Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108400727295933025Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
10450498Bp384Blood pressure QTL 3840.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1067750049107211142Rat
2300172Bmd57Bone mineral density QTL 579.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1069738412107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
2293646Bss25Bone structure and strength QTL 2510.960.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1069738412107211142Rat
2293663Bss33Bone structure and strength QTL 339.340.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1069738412107211142Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1085565469103884409Rat
12880395Cm109Cardiac mass QTL 1090.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1090404397107211142Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107624608594965338Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1051770177107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat
631535Cm51Cardiac mass QTL 513heart mass (VT:0007028)calculated heart weight (CMO:0000073)105178628291669536Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105112110096121100Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108400727295933025Rat
2293698Bss43Bone structure and strength QTL 435.330.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1059209888104209888Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062057807107057807Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_statistics_details obtained from analysis of F2 males only 1554311
qtl_statistics_details MAPMAKER/QTL 1.1 was used for linkage analysis 1554311