Bp258 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp258 (Blood pressure QTL 258) Rattus norvegicus

Symbol: Bp258
Name: Blood pressure QTL 258
RGD ID: 1549828
Previously known as: C2QTL3; BpcakmC2QTL3
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: 0.03
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22142,323,368 - 150,650,069RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.02148,295,267 - 158,268,703RGD_MAPPER_PIPELINERnor6.0
Rnor_5.02167,706,439 - 177,627,084RGDRnor5.0
RGSC_v3.42147,424,195 - 156,267,340RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: SS.MNS-(D2Chm51-D2Rat341)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Modularization and epistatic hierarchy determine homeostatic actions of multiple blood pressure quantitative trait loci. Chauvet C, etal., Hum Mol Genet. 2013 Nov 15;22(22):4451-9. doi: 10.1093/hmg/ddt294. Epub 2013 Jun 28.
2. Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis. Chauvet C, etal., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.
3. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.
4. Multiple quantitative trait loci for blood pressure interacting epistatically and additively on dahl rat chromosome 2. Dutil J, etal., Hypertension 2005 Apr;45(4):557-64. Epub 2005 Feb 28.
Related QTLs

Related QTL Description Reference
Bp310 interacts with RGD:7421500
Bp368 sub_region RGD:7421631
Bp346 interacts with RGD:7421500


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3242P2ry1purinergic receptor P2Y12145241975145248186Rat
3098Mmemembrane metallo-endopeptidase2147686913147803808Rat
619890Gpr149G protein-coupled receptor 1492146909710146981924Rat
70912P2ry14purinergic receptor P2Y142143372697143413213Rat
628779Clrn1clarin 12143084030143130948Rat
631440Aadacarylacetamide deacetylase2144163436144186086Rat
628668Mbnl1muscleblind-like splicing regulator 12144639819144814395Rat
620790Serp1stress-associated endoplasmic reticulum protein 12142757254142761243Rat
708515Vom2r44vomeronasal 2 receptor 442148497150148536036Rat
621630Ssr3signal sequence receptor subunit 32149605005149625069Rat
735030Igsf10immunoglobulin superfamily, member 102143575710143605044Rat
621681P2ry12purinergic receptor P2Y122143481468143523340Rat
620653Slc33a1solute carrier family 33 member 12148415660148438182Rat
1303193Sucnr1succinate receptor 12144219066144230568Rat
61827Kcnab1potassium voltage-gated channel subfamily A regulatory beta subunit 12149137025149603540Rat
620778Siah2siah E3 ubiquitin protein ligase 22142913924142931752Rat
620591Rap2bRAP2B, member of RAS oncogene family2145599714145600265Rat
1306812Vom2r45vomeronasal 2 receptor, 452148570788148597475Rat
620864Ccnl1cyclin L12150184865150199524Rat
735122Vom2r46vomeronasal 2 receptor, 462148628229148667383Rat
1308767Dhx36DEAH-box helicase 362146856469146894577Rat
1559813Vom2r47vomeronasal 2 receptor, 472148954547148990294Rat
1560703Tmed2l1transmembrane p24 trafficking protein 2 like 12147826229147828568Rat
1306171TiparpTCDD-inducible poly(ADP-ribose) polymerase2149753682149780327Rat
1310063Gmpsguanine monophosphate synthase2148441369148491908Rat
1308217Veph1ventricular zone expressed PH domain-containing 12150291379150537491Rat
1307852Gpr87G protein-coupled receptor 872143439741143440901Rat
1562559Arhgef26Rho guanine nucleotide exchange factor 262146740336146850918Rat
1563197Aadacl2arylacetamide deacetylase-like 22144123557144144159Rat
1561998Aadacl2fm2AADACL2 family member 22143883313143910452Rat
1559622Aadacl2larylacetamide deacetylase-like 2 like2143761288143800486Rat
1559451Erich6glutamate-rich 62142851905142878010Rat
1359128Selenotselenoprotein T2142804387142821438Rat
1560162Aadacl2fm2l1AADACL2 family member 2 like 12144077936144098546Rat
1560324Aadacl2fm3AADACL2 family member 32143936599143975506Rat
1302941P2ry13purinergic receptor P2Y132143470437143476360Rat
1565425Lekr1leucine, glutamate and lysine rich 12149889615150061167Rat
1565059C2h3orf33similar to human chromosome 3 open reading frame 332148376598148404343Rat
1585271Gpr171G protein-coupled receptor 1712143360402143365494Rat
1561991Plch1phospholipase C, eta 12148148908148363616Rat
1588660Tgap1l10GTPase activating protein testicular GAP1 like 102148873002148910171Rat
1593169Tsc22d2TSC22 domain family, member 22142646778142697977Rat
1592212Med12lmediator complex subunit 12L2143253048143576507Rat
1590976Mterf1-ps3mitochondrial transcription termination factor 1, pseudogene 32144912502144915405Rat
1589591Eif2aeukaryotic translation initiation factor 2A2142761303142794767Rat
1589858Pbk-ps1PDZ binding kinase, pseudogene 12146422640146423799Rat
1592031Eif5-ps3eukaryotic translation initiation factor 5, pseudogene 32147673787147675031Rat
1592032Ftl1l4ferritin light chain 1 like 42144606370144613638Rat
1593476Ptx3pentraxin 32150487513150493323Rat
1626029LOC691049hypothetical protein LOC6910492148946711148947253Rat
1625999Vom2r-ps74vomeronasal 2 receptor, pseudogene 742149091322149092214Rat
2318158Srsf10-ps2serine and arginine rich splicing factor 10, pseudogene 22145547075145547780Rat
2320352Rps13-ps8ribosomal protein S13, pseudogene 82142636554142636927Rat
2323965Fis1-ps1fission, mitochondrial 1, pseudogene 12147963640147976641Rat
6494152Hspd1-ps34heat shock protein family D (Hsp60) member 1, pseudogene 342146424660146426592Rat
6501779LOC100909772glyceraldehyde-3-phosphate dehydrogenase-like2150126497150127252Rat
7663730Strit1small transmembrane regulator of ion transport 12147935219147938083Rat
7651650LOC102554278uncharacterized LOC1025542782149660865149754798Rat
7736144LOC102551458uncharacterized LOC1025514582144249483144259818Rat
7675313Spin1-ps3spindlin 1, pseudogene 32148724097148725193Rat
9158000LOC103691561activated RNA polymerase II transcriptional coactivator p15 pseudogene2143786767143787385Rat
11362385Mindy4bMINDY family member 4B2143026685143061966Rat
11451529LOC108350188heterogeneous nuclear ribonucleoprotein A1 pseudogene2146203311146204345Rat
11380114Rpl7a-ps21ribosomal protein L7a, pseudogene 212143142439143143338Rat
11486538H3f3a-ps8H3.3 histone A, pseudogene 82150281751150282297Rat
11487723LOC108350022uncharacterized LOC1083500222145011388145080528Rat
41379557LOC120100831uncharacterized LOC1201008312143363352143370752Rat
41379567Zmynd8-ps1zinc finger, MYND-type containing 8, pseudogene 12144832892144834587Rat
41282001LOC120101015vomeronasal type-2 receptor 1-like2148709993148734340Rat
41206438LOC120101017glyceraldehyde-3-phosphate dehydrogenase-like2150125639150126427Rat
41253353Tgif1-ps1TGFB-induced factor homeobox 1, pseudogene 12144497737144530432Rat
41361295LOC120101291small nucleolar RNA SNORA172149087742149087872Rat
41146639Aadacl2fm3l1AADACL2 family member 3 like 12144000814144045928Rat
41211104LOC120100839uncharacterized LOC1201008392150566953150576886Rat
41264623LOC120100830uncharacterized LOC1201008302142885611142893347Rat
41392418LOC120101116U2 spliceosomal RNA2142505335142505414Rat
41098290Trnaa-agc101transfer RNA alanine (anticodon AGC) 1012150079977150080051Rat
41153850LOC120101261small nucleolar RNA SNORA482146703955146704098Rat
41191904LOC120101227small nucleolar RNA SNORD222149003015149003143Rat
41368909Rnu6-1286RNA, U6 small nuclear 12862147238286147238388Rat
41216218LOC120100832uncharacterized LOC1201008322144589149144602088Rat
41345252LOC120101314small nucleolar RNA SNORA172149074535149074665Rat
41184903Rnu6-173RNA, U6 small nuclear 1732144435226144435328Rat
41219350LOC120101207U6 spliceosomal RNA2147941537147941643Rat
41400276Rpl36a-ps11ribosomal protein L36A, pseudogene 112149786905149787372Rat
41272099LOC120100833protein FAM246C-like2144667224144670864Rat
41350546Trnas-aga30transfer RNA serine (anticodon AGA) 302145791195145791276Rat
41162710LOC120100834uncharacterized LOC1201008342146895653146915619Rat
41273282Hnrnpa1-ps44heterogeneous nuclear ribonucleoprotein A1, pseudogene 442150370609150371745Rat
40946467LOC120100827uncharacterized LOC1201008272142355389142413239Rat
40929886LOC120101210U6 spliceosomal RNA2149751422149751513Rat
40939051LOC120101244small nucleolar RNA SNORA282147675590147675715Rat
40966232LOC120101228small nucleolar RNA SNORD222149025675149025803Rat
41024370LOC120101133U4 spliceosomal RNA2144593202144593324Rat
41026717Vom2r1-ps1vomeronasal 2 receptor 1, pseudogene 12148844010148849771Rat
41050432LOC120101165U6 spliceosomal RNA2149399599149399701Rat
41144049Scarna14l3small Cajal body-specific RNA 14 like 32147594521147594655Rat
41300872LOC120100835vomeronasal type-2 receptor 1-like2148753589148785518Rat
41042241LOC120100836uncharacterized LOC1201008362149550630149576041Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10904D2Mco332422147752777147753017Ratregion
34005D2Mit81502143657411143657569Ratregion
34204D2Mgh72272150540301150540526Ratregion
33747D2Mit101212150341585150341684Ratregion
37330D2Rat1812132148478176148478373Ratregion
37034D2Rat371502145500022145500154Ratregion
36701D2Rat1461682144536601144536760Ratregion
36775D2Rat351622144228428144228589Ratregion
35162D2Rat381942149559561149559726Ratregion
35857D2Rat361272143157029143157156Ratregion
39754D2Rat2232212148076403148076632Ratregion
39842D2Rat2241052147958279147958374Ratregion
38312D2Rat1791692149246195149246378Ratregion
40328D2Rat2571292142843294142843423Ratregion
42599D2Rat3412002150090368150090572Ratregion
41128D2Rat2252432145196438145196688Ratregion
41834D2Rat3742002149406644149406843Ratregion
43532D2Got1091792150058033150058212Ratregion
43533D2Got1882262148083030148083256Ratregion
43533D2Got1882262148083030148083891Ratregion
43533D2Got1882262148083125148083256Ratregion
43534D2Got1971872150639095150639282Ratregion
43535D2Got1072772149380288149380565Ratregion
43536D2Got1062322148114971148115203Ratregion
60352D2Got881452148176358148176503Ratregion
60281D2Got1081302150341552150341682Ratregion
66367D2Mco381882145496743145496934Ratregion
67258D2Arb93102142709148142709417Ratregion
67258D2Arb93102142709148142709642Ratregion
67258D2Arb93102142709254142709417Ratregion
67751D2Uwm321992142909618142909825Ratregion
1358020D2Chm462042146785831146786035Ratregion
1358031D2Chm2251682150649899150650069Ratregion
1358049D2Chm512272146368688146368915Ratregion
1358052D2Chm902422142323368142323610Ratregion
1636528D2Got3321312144619698144619827Ratregion
1637487D2Got1052952147549114147549404Ratregion
7193078AA8921501022148362163148362265Ratregion
7193089D2Mgh271392142709158142709297Ratregion
7193089D2Mgh271392142709158142709642Ratregion
7206792RH1243264492148724497148724942Ratregion
5035979PMC34459P16522145242883145243535Ratregion
5031272PMC123072P22512145242893145243144Ratregion
5031754AU0472622392149249836149250066Ratregion
5026930RH1340802002143594767143594959Ratregion
5027245AI7887411312148415710148415841Ratregion
5032569WI-70703482150492709150493058Ratregion
5032583T035141902150185151150185341Ratregion
5030075BE1100111742143532319143532493Ratregion
5024976BB2423491242143439855143439979Ratregion
5030683BI3017922052143526741143526946Ratregion
5030893BI3021601932150284805150284998Ratregion
5054253RH1431181012142805005142805106Ratregion
5057532BF3920581182143482492143482610Ratregion
5054977RH1435341922150190597150190789Ratregion
5056179RH1442292912145608390145608681Ratregion
5058726BE1023891502146979424146979574Ratregion
5059664BE0975741702149603367149603537Ratregion
5056921RH1446571772142787364142787540Ratregion
5052424AI3156561402148415701148415841Ratregion
5059808BE0979451512143481728143481879Ratregion
5059154BF3875881932147708492147708685Ratregion
5059212BF3876811822150487923150488105Ratregion
505242239.MHAa90d3.seq1812147741027147741208Ratregion
5051348AU0221841092146858763146858872Ratregion
5041668RH1289891502148415698148415848Ratregion
5048726RH1330701822149779918149780100Ratregion
5045276RH1310852022142821203142821405Ratregion
5048138RH13273002142794269142794452Ratregion
5046986RH1320692202147803084147803304Ratregion
5042084RH1292301802142758935142759115Ratregion
5048534RH1329581932150296614150296807Ratregion
5049520RH1335281912146190773146190964Ratregion
5040646RH1284021972146856637146856834Ratregion
5043726RH1301911942150184898150185092Ratregion
5043144RH1298571832144814118144814301Ratregion
5077500RH1397922172144669731144669948Ratregion
5076426RH1391681812143445419143445598Ratregion
5076510RH1392171582149605383149605541Ratregion
5078042RH1401091822149606340149606522Ratregion
5078160RH1401781802147806307147806487Ratregion
5078836RH1405801572147801884147802041Ratregion
5071790RH1352861872148478935148479122Ratregion
5071036RH1348491802143557296143557476Ratregion
5065122BF4059881592145244674145244834Ratregion
5066666AU0482221442150211342150211486Ratregion
5067734AU0475681322150211353150211485Ratregion
5067944AU0474432152149502816149503031Ratregion
5068696AU0469891012149923713149923814Ratregion
5069997RH944091522147803242147803394Ratregion
5065422BE1154491502146863018146863168Ratregion
5060982BF3896361212148427724148427845Ratregion
5060386AW5319861602149660931149661091Ratregion
5060928BF3894732472147807417147807664Ratregion
5062872BE1131861642150136251150136415Ratregion
5062948BF4100862152143505177143505392Ratregion
5064474BE1080441652148479491148479656Ratregion
5063152BI3013761502146019213146019363Ratregion
5066442AU0483542792146569293146569572Ratregion
5061652BF3969921872142649265142649452Ratregion
5088076Ptx35422150492708150493251Ratregion
5088161AU0484043452150526595150527094Ratregion
5083575BI276286992143252273143252372Ratregion
5089629AU0492682322149356488149356720Ratregion
5085405AI5994201632149779559149779722Ratregion
5090219AU0496211802150639110150639290Ratregion
5081374AI0713841802143470511143470691Ratregion
5082559BE1197011512149575300149575451Ratregion
5082575BE1197631782149568558149568736Ratregion
5086217BQ2060622182146738594146738812Ratregion
5081200RH1420221802150294889150295069Ratregion
5083123BF3908091932143471685143471877Ratregion
5081617BE1176411552145247400145247555Ratregion
5085571BQ1991821602142693381142693541Ratregion
5081991BE1189991502144667617144667767Ratregion
5083731AA8921502142148361971148362185Ratregion
5504554PMC304098P41082150492367150492475Ratregion
5507033fl05f09.x12002145599793145599993Ratregion
5502561RH1253401832142820626142820809Ratregion
Position Markers

Flank 1: (D2Chm90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22142,323,368 - 142,323,610 (+)MAPPER
Rnor_6.02148,295,267 - 148,295,508NCBI
Rnor_5.02167,706,439 - 167,706,680UniSTS
RGSC_v3.42147,424,195 - 147,424,436UniSTS
Celera2136,755,765 - 136,756,448UniSTS
Celera2136,755,765 - 136,755,986UniSTS
Cytogenetic Map2 RGD
Flank 2: (D2Chm225)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22150,649,899 - 150,650,069 (+)MAPPER
Rnor_6.02158,268,536 - 158,268,703NCBI
Rnor_5.02177,626,917 - 177,627,084UniSTS
RGSC_v3.42156,267,173 - 156,267,340UniSTS
Celera2145,057,182 - 145,057,349UniSTS
Cytogenetic Map2 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2104559726149559726Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2112103657148076632Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1354594Despr10Despair related QTL 100.00000249locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2114654253159654253Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527143657569Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527143657569Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
5135226Leukc2Leukocyte quantity QTL 2eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)2118111229149559726Rat
1582257Gluco21Glucose level QTL 213.10.0035blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2118111229157142209Rat
738007Anxrr7Anxiety related response QTL 74.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2118189491163189491Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2127447387143657569Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
12879830Bw178Body weight QTL 1780.001body mass (VT:0001259)body weight (CMO:0000012)2137219876142323610Rat
12879831Cm82Cardiac mass QTL 820.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2137219876142323610Rat
12879832Cm83Cardiac mass QTL 830.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2137219876142323610Rat
12879833Cm84Cardiac mass QTL 840.001heart right ventricle mass (VT:0007033)heart weight to body weight ratio (CMO:0000074)2137219876142323610Rat
12879834Am1Aortic mass QTL 10.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2137219876142323610Rat
12879835Kidm60Kidney mass QTL 600.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2137219876142323610Rat
1549841Bp256Blood pressure QTL 2560.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2137219876142323610Rat
7488931Bp367Blood pressure QTL 3670.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2139401804142323610Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
12879841Cm87Cardiac mass QTL 870.026heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2142323368146786035Rat
12879842Cm88Cardiac mass QTL 880.042heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2142323368146786035Rat
12879843Am3Aortic mass QTL 30.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2142323368146786035Rat
12879844Kidm62Kidney mass QTL 620.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2142323368146786035Rat
7488933Bp368Blood pressure QTL 3680.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2142323368147803808Rat
1549828Bp258Blood pressure QTL 2580.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2142323368150650069Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general shows additive effect to Bp257 1357413
qtl_general number of animals used: 8 gender: male 1599557
qtl_general also affects heart left ventricle mass, heart mass, aortic mass and kidney mass, but has no effect on heart right ventricle mass or body mass 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age; telemetric probes were implanted at 56 days of age and blood pressure recorded after 10 days 1599557