Srcrt5 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Srcrt5 (Stress Responsive Cort QTL 5) Rattus norvegicus

Symbol: Srcrt5
Name: Stress Responsive Cort QTL 5
RGD ID: 1358354
Trait: blood corticosterone amount   (VT:0005345)    
Measurement Type: plasma corticosterone level   (CMO:0001173)    
LOD Score: 3.38
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21598,150,001 - 99,043,291RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.015105,348,517 - 108,369,033RGD_MAPPER_PIPELINERnor6.0
Rnor_5.015108,749,721 - 111,756,589RGDRnor5.0
RGSC_v3.415106,152,589 - 107,060,711RGDRGSC3.4
RGSC_v3.115106,168,381 - 107,076,479RGD
Cross Type: Not Available
Strains Crossed: WKY/NHsd F344/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
F344/NHsd  (IEA)
WKY/NHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genetic analysis of the stress-responsive adrenocortical axis. Solberg LC, etal., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1305346Farp1FERM, ARH/RhoGEF and pleckstrin domain protein 1159812430498363299Rat
1561742Stk24serine/threonine kinase 24159836370798458940Rat
41131757LOC120097091uncharacterized LOC120097091159851081998516020Rat
621736Slc15a1solute carrier family 15 member 1159853764198582544Rat
9107661Lnc004long non-coding RNA 004159854437898555224Rat
629617Dock9dedicator of cytokinesis 9159861151898883306Rat
41110278LOC120097092uncharacterized LOC120097092159862478398629732Rat
1311689Ubac2UBA domain containing 2159896013999107795Rat
1304889Gpr18G protein-coupled receptor 18159899742799001177Rat
1598095Gpr183G protein-coupled receptor 183159903776499050550Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
35321D15Rat27138159904314899043291Ratregion
38106D15Rat50211159859654598596747Ratregion
40516D15Rat106173159828795598288169Ratregion
60088D15Got114155159881462698814775Ratregion
5037107RH48488129159837232498372822Ratregion
5028817RH142443151159862446598625020Ratregion
5034828AI408540171159899746998997640Ratregion
5027481AW22884498159836289898362996Ratregion
5042242RH129322204159836375798363961Ratregion
5043816RH130244208159836583798366046Ratregion
5072508RH136890216159836374798363963Ratregion
5074910RH138289176159832959298329768Ratregion
5080642RH141698215159864567098645885Ratregion
5080710RH141737182159836204098362222Ratregion
5076344RH139121156159832718498327340Ratregion
5076374RH139138249159833020498330453Ratregion
5066080BE116755177159830785198308028Ratregion
5084308AA848951214159861838598618599Ratregion
5086987BE107531150159824078198240931Ratregion
5084876AI229437182159821597898216160Ratregion
Position Markers

Flank 1: (D15Rat40)
Rat AssemblyChrPosition (strand)Source
Celera1576,226,865 - 76,227,019UniSTS
RH 2.0 Map15404.7RGD
SHRSP x BN Map1549.5298RGD
FHH x ACI Map1563.69RGD
Cytogenetic Map15q21UniSTS
Peak: (D15Rat50)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21598,596,545 - 98,596,747 (+)MAPPER
Rnor_6.015106,858,673 - 106,858,877NCBI
Rnor_5.015110,253,053 - 110,253,257UniSTS
RGSC_v3.415106,606,473 - 106,606,827RGD
RGSC_v3.415106,606,595 - 106,606,799UniSTS
RGSC_v3.115106,622,253 - 106,622,607RGD
RH 3.4 Map15708.8UniSTS
RH 3.4 Map15708.8RGD
RH 2.0 Map15607.1RGD
SHRSP x BN Map1566.5498RGD
Flank 2: (D15Rat27)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21599,043,148 - 99,043,291 (+)MAPPER
Rnor_6.015108,368,891 - 108,369,033NCBI
Rnor_5.015111,756,447 - 111,756,589UniSTS
RGSC_v3.415107,060,557 - 107,060,699UniSTS
RGSC_v3.415107,060,381 - 107,060,711RGD
RGSC_v3.115107,076,337 - 107,076,479RGD
Celera1597,815,670 - 97,815,812UniSTS
RH 3.4 Map15706.5RGD
RH 3.4 Map15706.5UniSTS
RH 2.0 Map15609.8RGD
SHRSP x BN Map1566.4899RGD
FHH x ACI Map1574.04RGD
Cytogenetic Map15q25UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)158226252098288169Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)159815000199043291Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)158226252098288169Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)157369051899794247Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 486 F2 animals 1598980
qtl_general software package used: Pseudomarker (release 1.02) 1598980