Rf36 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Rf36 (Renal function QTL 36) Rattus norvegicus

Symbol: Rf36
Name: Renal function QTL 36
RGD ID: 1331782
Previously known as: Specialized Center of Research QTL 22; SCOR22
Trait: kidney blood vessel physiology trait   (VT:0100012)    
Measurement Type: absolute change in renal blood flow rate   (CMO:0001168)    
LOD Score: 3.296
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2583,840,598 - 97,059,958RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0585,800,910 - 100,745,614RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0539,377,361 - 104,771,061RGDRnor5.0
RGSC_v3.4535,390,492 - 101,506,667RGDRGSC3.4
RGSC_v3.1535,390,671 - 101,511,887RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
# Reference Title Reference Citation
1. A genomic-systems biology map for cardiovascular function. Stoll M, etal., Science 2001 Nov 23;294(5547):1723-6.
Related QTLs

Related QTL Description Reference
Rf34 maps to same region RGD:70849
Scl26 maps to same region RGD:70849
Rf33 maps to same region RGD:70849
Rf35 maps to same region RGD:70849
Rf32 maps to same region RGD:70849


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
708451Cdk5rap2CDK5 regulatory subunit associated protein 258379228283961129Rat
41186256LOC120102900uncharacterized LOC12010290058396088483976651Rat
1308330Megf9multiple EGF-like-domains 958399356584105622Rat
9685074Mir3084cmicroRNA 3084c58417737584177443Rat
2324484Sppl3-ps1signal peptide peptidase like 3, pseudogene 158426997084278377Rat
1585621Rgccl1regulator of cell cycle like 158428089784281785Rat
9106595LOC103692379small ubiquitin-related modifier 3 pseudogene58527277285273104Rat
6491129Slc25a4-ps1solute carrier family 25 member 4, pseudogene 158540968985410315Rat
41169748LOC120103074uncharacterized LOC12010307458543843585440033Rat
11383413LOC108351095serine/arginine repetitive matrix protein 1-like58544262085444118Rat
413197023110040M04Rikl6RIKEN cDNA 3110040M04 gene like 658544663085448161Rat
409444813110040M04Rikl3RIKEN cDNA 3110040M04 gene like 358545186285453391Rat
41198326LOC120103077uncharacterized LOC12010307758545591285457437Rat
412384113110040M04Rikl4RIKEN cDNA 3110040M04 gene like 458545995885461489Rat
11433168LOC108351130uncharacterized LOC10835113058546400885465546Rat
410207263110040M04Rikl5RIKEN cDNA 3110040M04 gene like 558546807885469609Rat
41193095LOC120103080uncharacterized LOC12010308058547212485473655Rat
114872973110040M04Rikl1RIKEN cDNA 3110040M04 gene like 158547618585477725Rat
1592335Smarca2-ps2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, pseudogene 258551439885523157Rat
41325019LOC120103336small nucleolar RNA SNORA1758566586285665987Rat
1309237Tle1TLE family member 1, transcriptional corepressor58585182785934806Rat
41197324LOC120103332small nucleolar RNA SNORA1758675458386754709Rat
2324113Zfp101l1zinc finger protein 101 like 158687095386873370Rat
2324063Oma1-ps1OMA1 zinc metallopeptidase, pseudogene 158691306886915146Rat
41357879LOC120103337small nucleolar RNA SNORA1758699225086992375Rat
41164090Rpl34-ps8ribosomal protein L34, pseudogene 858701752187020226Rat
1592267Rps18-ps6ribosomal protein S18, pseudogene 658725020087250683Rat
41145427LOC120103327small nucleolar RNA SNORA1758750390987504029Rat
1306418RasefRAS and EF hand domain containing58754890887619286Rat
41144701LOC120102901uncharacterized LOC12010290158759930187602345Rat
11502494LOC108351096dnaJ homolog subfamily B member 1 pseudogene58768168087682686Rat
13595842310002L09RiklRIKEN cDNA 2310002L09 like58769273387706183Rat
1304802Frmd3FERM domain containing 358776475588031091Rat
11381374LOC108350987COMM domain-containing protein 2 pseudogene58802717288030854Rat
1562410Dppa3-ps2developmental pluripotency-associated 3, pseudogene 258809741888098963Rat
1307528Kdm4clysine demethylase 4C58810071088306821Rat
1589969Rpl9-ps24ribosomal protein L9, pseudogene 2458836086588361547Rat
41155933LOC120103302small nucleolar RNA SNORA1758857255288572680Rat
1589947Vom2r-ps76vomeronasal 2 receptor, pseudogene 7658869625688791737Rat
1309148Dmac1distal membrane arm assembly component 158924117389243793Rat
1589924Eef1g-ps16eukaryotic translation elongation factor 1 gamma, pseudogene 1658926144489263004Rat
2324835Mdh2-ps1malate dehydrogenase 2, pseudogene 158998218289984494Rat
1561090Ptprdprotein tyrosine phosphatase, receptor type, D59004699390698977Rat
41025543LOC120103209U6 spliceosomal RNA59060509090605193Rat
41013620Cog5-ps1component of oligomeric golgi complex 5, pseudogene 159064539790816683Rat
41344762Drg1-ps2developmentally regulated GTP binding protein 1, pseudogene 259089386490972201Rat
41309747LOC120103065uncharacterized LOC12010306559097382590991561Rat
1561090Ptprdprotein tyrosine phosphatase, receptor type, D59112235491641754Rat
7703644Ptprdlprotein tyrosine phosphatase, receptor type, D like59236841092380389Rat
41085030Zcchc9-ps3zinc finger CCHC-type containing 9, pseudogene 359239049992406353Rat
7558064LOC102555405uncharacterized LOC10255540559296352893021460Rat
1586073Ccdc47-ps1coiled-coil domain containing 47, pseudogene 159302161393023608Rat
41142637LOC120103155uncharacterized LOC12010315559306583793073188Rat
7746436LOC102555669uncharacterized LOC10255566959307964493197365Rat
2320392Pwp1-ps1PWP1 homolog, endonuclein, pseudogene 159323345393237397Rat
1563375Snrpn-ps4small nuclear ribonucleoprotein polypeptide N, pseudogene 459364967993650898Rat
9120358Hmgn4-ps6high mobility group nucleosomal binding domain 4, pseudogene 659405577094062563Rat
1587537Akr1b8-ps3aldo-keto reductase family 1, member B8, pseudogene 359428666894291222Rat
1587526Dkc1-ps3dyskerin pseudouridine synthase 1, pseudogene 359432124594322841Rat
1564021Rpl31-ps1ribosomal protein L31, pseudogene 159494831294948698Rat
41322042Fth1-ps2ferritin heavy chain 1, pseudogene 259508626195087200Rat
1586398Hpf1-ps1histone PARylation factor 1, pseudogene 159519946895200056Rat
41168764LOC120103291small nucleolar RNA SNORA4859520289795203037Rat
1593266Tyrp1tyrosinase-related protein 159528098295299516Rat
7509921LOC102556039uncharacterized LOC10255603959528349895314373Rat
1308059Lurap1lleucine rich adaptor protein 1-like59536200595409439Rat
1565987Fbxl18l1F-box and leucine-rich repeat protein 18 like 159546048095464873Rat
40972972LOC120102902protein PRRC2C-like59555314795562018Rat
11458786LOC108350991uncharacterized LOC10835099159566871795710953Rat
3105Mpdzmultiple PDZ domain crumbs cell polarity complex component59576611295920531Rat
40971150LOC120103321small nucleolar RNA SNORA1759583074095830865Rat
41044958LOC120103373U4 spliceosomal RNA59625456696254697Rat
41332442LOC120103156uncharacterized LOC12010315659638721896389315Rat
62015Nfibnuclear factor I/B59675920896974001Rat
6497980LOC100910558uncharacterized LOC10091055859697618197014187Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33981D5Mit426659045014490450412Ratregion
36135D5Rat2016858463946784639641Ratregion
37690D5Rat9223859559615095596396Ratregion
36558D5Rat1916858672382786724018Ratregion
35032D5Rat1816058886887988869033Ratregion
35577D5Rat2116659511206595112231Ratregion
39796D5Rat15023659607117596071342Ratregion
38308D5Rat10716159040530290405423Ratregion
40384D5Rat18313059628554396285673Ratregion
38700D5Rat8524758592266185922904Ratregion
38848D5Rat8823659528829395288541Ratregion
39224D5Rat9822959577419495774399Ratregion
39378D5Rat14920459705976097059958Ratregion
42765D5Rat25822158534999385350219Ratregion
41776D5Rat21121459161836791618574Ratregion
43921D5Got12622458499908584999311Ratregion
43922D5Got2112558528618185286306Ratregion
43923D5Got12516158592818985928350Ratregion
43928D5Wox312059485897294859095Ratregion
43929D5Got12823659682413896824374Ratregion
45054D13Got229459354117093542503Ratregion
60479D5Got2413259145437491454506Ratregion
66700D5Mco3312858648036786480495Ratregion
67270D5Arb28158651684186516922Ratregion
67766D5Uwm112458952483989524947Ratregion
67768D5Uwm212059661487496614994Ratregion
1630234D5Got27221758736218087362397Ratregion
1631934D5Got28722359099380990994032Ratregion
1639076D5Got2378758529613985296226Ratregion
1632630D5Got23818359120129891201464Ratregion
1640190D5Got31226459579395095794214Ratregion
1636554D5Got25418359219051992190702Ratregion
1636896D5Got25622159586086995861088Ratregion
5035763D9S201212659675922396759349Ratregion
5036221D4Bwg0951e12859540930895409436Ratregion
5036755AU04910117458629004386290217Ratregion
5031500AU04811920059257105992571259Ratregion
5031640AU04764615559702564597025900Ratregion
5031640AU04764615559702574597025900Ratregion
5031916AU04671620958742166287421871Ratregion
5034698AI70391721659024019690240412Ratregion
5032261AV0779788159540931095409391Ratregion
5035106AFM324zg9059518271695183352Ratregion
5029923BE09784221959026354490263763Ratregion
5033307RH13835315759578234695782503Ratregion
5025322RH12787221358924285089243063Ratregion
5028328WI-1264610358585224985852352Ratregion
5031205RH10424113658391206483912200Ratregion
5055035RH14356821459678769196787905Ratregion
5057928BF38633315058784566087845810Ratregion
5050696RH13420520658398656583986771Ratregion
5051100RH13444020559576630895766513Ratregion
5053921RH14292816759678668896786855Ratregion
5052757RH14225618259004860190048779Ratregion
5051376AV17513712959540931095409439Ratregion
5054855RH14346415058801192888012078Ratregion
5050868RH13430419459529928295299476Ratregion
5043902RH13029418158395941783959598Ratregion
5045990RH13149520659545789895458104Ratregion
5045990RH13149520659545789895458104Ratregion
5048886RH13316221358769278287692995Ratregion
5046760RH13193918059238012192380301Ratregion
5046904RH13202119059701398197014171Ratregion
5075968RH13890118959004929590049484Ratregion
5074804RH13822815058594172985941879Ratregion
5074976RH13832718858761906087619248Ratregion
5075204RH13845920459678619796786401Ratregion
5079594RH14109019158585197785852168Ratregion
5079734RH14117218359086275390862934Ratregion
5071676RH13522021459237511392375327Ratregion
5071476RH13510418959005028390050472Ratregion
5067602AU04764722659702564597025906Ratregion
5067602AU04764722659702568097025906Ratregion
5067616AU04763813058755826887558398Ratregion
5067620AU04763520559702564597025900Ratregion
5067620AU04763520559702570097025900Ratregion
5067626AU04763122458755818287558405Ratregion
5068114AU04733916059136021391360373Ratregion
5068364AU04719116959197748691977657Ratregion
5069592AU04639423859579395095794188Ratregion
5065598BF40600013859535700295357141Ratregion
5061998BE11247818259545829895458480Ratregion
5061998BE11247818259545829895458480Ratregion
5064378BF39916818759135938591359572Ratregion
5061290BI28703617859218396692184144Ratregion
5062994BF41012023859016652190166760Ratregion
5088407AU0485519859597318695973284Ratregion
5082379BI27461918259675951596759697Ratregion
5088591AU04866116559219947392199638Ratregion
5088591AU04866116559219947392199848Ratregion
5088935AU04885717059366719593667365Ratregion
5503142PTPRD059006061290061733Ratregion
5501398Mpdz059587464695875800Ratregion
5504926Nfib5259696342296963474Ratregion
5501940MARC_17865-17866:1025013775:148759676516596765652Ratregion
5502224G64294150359248199492483497Ratregion
5502321RH12445215059432170494321854Ratregion
Position Markers

Flank 1: (D5Rat131)
Rat AssemblyChrPosition (strand)Source
Rnor_5.0539,377,361 - 39,377,516NCBI
RGSC_v3.4535,390,492 - 35,390,646RGD
RGSC_v3.1535,390,671 - 35,390,825RGD
SHRSP x BN Map520.43RGD
SHRSP x BN Map520.43UniSTS
Peak: (D5Mit4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2590,450,144 - 90,450,412 (+)MAPPER
Rnor_6.0593,273,130 - 93,273,395NCBI
Rnor_5.0597,315,057 - 97,315,322UniSTS
RGSC_v3.4594,515,803 - 94,516,069RGD
RGSC_v3.4594,515,804 - 94,516,069UniSTS
RGSC_v3.1594,520,917 - 94,521,182RGD
Celera589,134,454 - 89,134,719UniSTS
RH 3.4 Map5696.7RGD
RH 3.4 Map5696.7UniSTS
Cytogenetic Map5q31UniSTS
Flank 2: (D5Rat149)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2597,059,760 - 97,059,958 (+)MAPPER
Rnor_6.05100,745,417 - 100,745,614NCBI
Rnor_6.05100,723,739 - 100,723,936NCBI
Rnor_5.05104,770,864 - 104,771,061UniSTS
Rnor_5.05104,751,414 - 104,751,611UniSTS
RGSC_v3.45101,506,464 - 101,506,661UniSTS
RGSC_v3.45101,506,332 - 101,506,667RGD
RGSC_v3.15101,511,690 - 101,511,887RGD
Celera595,614,587 - 95,614,784UniSTS
RH 3.4 Map5723.5UniSTS
RH 3.4 Map5723.5RGD
SHRSP x BN Map553.6299RGD
SHRSP x BN Map553.6299UniSTS
Cytogenetic Map5q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)58384059897059958Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Rf36

RGD Curation Notes
Note Type Note Reference
qtl_general change in renal blood flow from acetylcholine dose 2 minus pre-Ach control (SCOR22) 70849
qtl_general additional information, including phenotype and mapping information, can be found at A genomics-systems biology map for cardiovascular function 70849