Stl29 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Stl29 (Serum triglyceride level QTL 29) Rattus norvegicus

Symbol: Stl29
Name: Serum triglyceride level QTL 29
RGD ID: 1302791
Previously known as: Tgl9; Triglyceride level QTL 9
Trait: blood triglyceride amount   (VT:0002644)    
Measurement Type: plasma triglyceride level   (CMO:0000548)    
LOD Score: 3.3
P Value: 0.0011
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21384,730,788 - 86,800,898RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01390,652,874 - 92,916,783RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01395,174,535 - 97,381,801RGDRnor5.0
RGSC_v3.41388,260,176 - 90,551,272RGDRGSC3.4
RGSC_v3.11388,449,060 - 90,740,156RGD
Cross Type: Not Available
Strains Crossed: LEW HTG 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
HTG  (IEA)
LEW  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Rat model of familial combined hyperlipidemia as a result of comparative mapping. Ueno T, etal., Physiol Genomics 2004 Mar 12;17(1):38-47. Epub 2004 Jan 6.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2168Atp1a2ATPase Na+/K+ transporting subunit alpha 2138472959784754544Rat
2411CrpC-reactive protein138513538485175178Rat
61822Kcnj10potassium inwardly-rectifying channel, subfamily J, member 10138480202684835383Rat
68322Apcsamyloid P component, serum138537321985374195Rat
2597Fcer1aFc epsilon receptor Ia138568609985692394Rat
621440Kcnj9potassium inwardly-rectifying channel, subfamily J, member 9138478082684787928Rat
71041Pigmphosphatidylinositol glycan anchor biosynthesis, class M138483832984842026Rat
1304566Igsf9immunoglobulin superfamily, member 9138494864384965616Rat
1306263Slamf8SLAM family member 8138504772985057571Rat
1305194Spta1spectrin, alpha, erythrocytic 1138620350486279371Rat
1306089Mndamyeloid cell nuclear differentiation antigen138601788886035556Rat
1307035Cadm3cell adhesion molecule 3138578478585817412Rat
1311500Igsf8immunoglobulin superfamily, member 8138477034884781534Rat
1333906Or10z1olfactory receptor family 10 subfamily Z member 1138628153586282476Rat
1333649Or10aa1b-ps1olfactory receptor family 10 subfamily AA member 1B, pseudogene 1138606359486064132Rat
1307283Aim2absent in melanoma 2138586520685906996Rat
1332837Or10at1-ps1olfactory receptor family 10 subfamily AT member 1, pseudogene 1138553163685532241Rat
1333957Or6k6olfactory receptor family 6 subfamily K member 6138614840286149325Rat
1333297Olr1585olfactory receptor 1585138605849786063730Rat
1333184Or10x1olfactory receptor family 10 subfamily X member 1138631619586317124Rat
1332648Or10j27olfactory receptor family 10 subfamily J member 27138559008285591014Rat
1332672Or6k4olfactory receptor family 6 subfamily K member 14B138616424486165191Rat
1563939Fcrl6Fc receptor-like 6138506270985072308Rat
1332683Or6k14bolfactory receptor family 6 subfamily K member 14B138613614486137094Rat
1333702Or10j5olfactory receptor family 10 subfamily J member 5138543065585431584Rat
1332808Or10j7olfactory receptor family 10 subfamily J member 7138564779685648728Rat
1332878Or6k3-ps1olfactory receptor family 6 subfamily K member 3, pseudogene 1138617194186172895Rat
1305945Slamf9SLAM family member 9138494189684944749Rat
1309202Dusp23dual specificity phosphatase 23138509789985100054Rat
1310840Tagln2transgelin 2138496698084973973Rat
1333784Or6k2olfactory receptor family 6 subfamily K member 2138618644286190391Rat
1561559Cfap45cilia and flagella associated protein 45138498947485012880Rat
1334338Or6k8olfactory receptor family 6 subfamily K member 8138618057986181526Rat
1562462Ifi214interferon activated gene 214138594002885951004Rat
1560008Grem2gremlin 2, DAN family BMP antagonist138677854386871509Rat
1332986Or6p1olfactory receptor family 6 subfamily P member 1138635189386352846Rat
1334126Olr1578-psolfactory receptor pseudogene 1578138554676985547308Rat
1332994Or6k14olfactory receptor family 6 subfamily K member 14138611619286117139Rat
1333597Or6n2olfactory receptor family 6 subfamily N member 2138607685786087100Rat
1334435Or6n1olfactory receptor family 6 subfamily N member 1138610691286107850Rat
1334438Or10as1-ps1olfactory receptor family 10 subfamily AS member 1, pseudogene 1138535825685359000Rat
1334407Or10aa3olfactory receptor family 10 subfamily AA member 3138607555786076495Rat
1333029Or10j29-ps1olfactory receptor family 10 subfamily J member 29, pseudogene 1138560387185604691Rat
1333448Or10j3bolfactory receptor family 10 subfamily J member 3B138568058185681522Rat
1334087Or10aa1olfactory receptor family 10 subfamily AA member 1138604615886052356Rat
1334224Or6y1olfactory receptor family 6 subfamily Y member 1138639338186394358Rat
1333672Or10j3olfactory receptor family 10 subfamily J member 3138566725485668195Rat
1333675Or10x1bolfactory receptor family 10 subfamily X member 1B138629756086298492Rat
1333301Or10l2-ps1olfactory receptor family 10 subfamily L member 2, pseudogene 1138630589086307068Rat
1562464Vsig8V-set and immunoglobulin domain containing 8138502317785031364Rat
1563410Actb-ps2actin, beta, pseudogene 2138644329486444338Rat
1590926Mptx1mucosal pentraxin 1138572798985731523Rat
1595361Or10j2olfactory receptor family 10 subfamily J member 2138572330085724290Rat
1596198Ackr1atypical chemokine receptor 1138578239685784015Rat
2322099Fmn2formin 2138645425686771437Rat
7636450LOC102556096pyrin domain-containing protein 3-like138591191585929491Rat
9205262LOC103692291uncharacterized LOC103692291138487114684872631Rat
11355415LOC108352575uncharacterized LOC108352575138490018384924193Rat
11428601LOC10835262160S ribosomal protein L6 pseudogene138523853785250025Rat
11418586LOC108353436uncharacterized LOC108353436138492426084925715Rat
11355992Trnar-ucu5transfer RNA arginine (anticodon UCU) 5138583980485839877Rat
11376557Rps29-ps16ribosomal protein S29, pseudogene 16138528463885284949Rat
11393231LOC108352577uncharacterized LOC108352577138542401185436529Rat
41107089Trnal-cag13transfer RNA leucine (anticodon CAG) 13138592234185922423Rat
40960097LOC120096401small nucleolar RNA SNORA17138541292985413048Rat
41061811LOC120096318uncharacterized LOC120096318138500516185018197Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10204D13Arb11215138475327784753511Ratregion
10205D13Mgh17399138475311384753510Ratregion
10569D13Wox17223138568589585686118Ratregion
34540D13Mgh14238138475531884755556Ratregion
33644D13Mit4114138680077686800898Ratregion
40568D13Rat152137138558107385581182Ratregion
41970D13Arb13127138473106684731198Ratregion
45079D13Wox8111138473078884730899Ratregion
45081D13Got72254138473752984737783Ratregion
66513D13Mco6350138501485385015182Ratregion
66718D13Mco22210138609270586092913Ratregion
1635055D13Wox19173138475723584757410Ratregion
7206022Olfr16733138543084585431578Ratregion
5038818RH127350214138677873786778951Ratregion
5036087Atp1a2126138473271484732985Ratregion
5036127Crp152138516286385163015Ratregion
5038968RH127436216138483489584835111Ratregion
5027207AV054416146138572808185728227Ratregion
5027579AI644422140138483793684838076Ratregion
5030389BF397101240138664071086640950Ratregion
5025278RH127703195138537342185373616Ratregion
5059954BF388208216138677965686779872Ratregion
5059958BF388231164138657007886570242Ratregion
5047566RH132401211138477923684779447Ratregion
5045656RH131303217138597524485975461Ratregion
5049046RH133255186138578669985786885Ratregion
5049812RH133696216138497367384973889Ratregion
5074128RH137838218138477980484780022Ratregion
5075030RH138358143138578494685785089Ratregion
5077856RH139999195138501763185017826Ratregion
5079948RH141295191138484045184840642Ratregion
5071416RH135069202138473141884732703Ratregion
5074028RH137777127138509793485098061Ratregion
5065116BF405930223138662017086620393Ratregion
5070231RH9454899138568616085686259Ratregion
5060048BE103703180138495750184957681Ratregion
5065824BE109994209138484259684842805Ratregion
5087852AA162249166138578256385782729Ratregion
5089153AU048986107138572443685724473Ratregion
5087850AA03317280138477752284777602Ratregion
5085208Kcnj9174138478131384781487Ratregion
5090067AU049530126138497252284972648Ratregion
5085006AI103968195138496528484965479Ratregion
5085278BE095854163138578246885782631Ratregion
5085882AI013247235138497361184973846Ratregion
5507237G64928138138483133584831473Ratregion
5501447Tagln2198138497177684972365Ratregion
5506704G42052229138478442084784649Ratregion
Position Markers

Flank 1: (D13Wox8)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21384,730,788 - 84,730,899 (+)MAPPER
Rnor_6.01390,652,874 - 90,652,984NCBI
Rnor_5.01395,174,535 - 95,174,645UniSTS
RGSC_v3.41388,260,176 - 88,260,287RGD
RGSC_v3.41388,260,177 - 88,260,287UniSTS
RGSC_v3.11388,449,060 - 88,449,171RGD
Celera1384,340,854 - 84,340,964UniSTS
RH 3.4 Map13554.6UniSTS
RH 3.4 Map13554.6RGD
RH 2.0 Map13607.5RGD
Cytogenetic Map13q24-q26UniSTS
Peak: (D13Rat34)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21388,384,747 - 88,384,959 (+)MAPPER
Rnor_6.01394,510,698 - 94,510,909NCBI
Rnor_5.01398,965,487 - 98,965,698UniSTS
RGSC_v3.41392,212,025 - 92,212,236UniSTS
RGSC_v3.41392,212,024 - 92,212,236RGD
RGSC_v3.11392,400,909 - 92,401,120RGD
Celera1387,967,091 - 87,967,302UniSTS
RH 3.4 Map13589.7RGD
RH 3.4 Map13589.7UniSTS
RH 2.0 Map13641.1RGD
SHRSP x BN Map1340.7498RGD
Flank 2: (D13Mit4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21386,800,776 - 86,800,898 (+)MAPPER
Rnor_6.01392,916,662 - 92,916,783NCBI
Rnor_5.01397,381,680 - 97,381,801UniSTS
RGSC_v3.41390,551,150 - 90,551,272RGD
RGSC_v3.41390,551,151 - 90,551,272UniSTS
RGSC_v3.11390,740,035 - 90,740,156RGD
Celera1386,401,644 - 86,401,765UniSTS
RH 3.4 Map13573.9UniSTS
RH 3.4 Map13573.9RGD
RH 2.0 Map13638.1RGD
SHRSP x BN Map1340.7498RGD
Cytogenetic Map13q24UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138473078886800898Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Tgl9


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-01 Stl29  Serum triglyceride level QTL 29  Tgl9  Triglyceride level QTL 9  Name updated 68913 APPROVED
2012-10-01 Stl29  Serum triglyceride level QTL 29  Tgl9  Triglyceride level QTL 9  Symbol updated 68687 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_general QTL is sex-specific to females 1299960
qtl_general homozygous HTG and heterozygous genotypes are associated with significantly higher plasma triglycerides than homozygous LEW genotype 1299960
qtl_general LOD 2.7 was observed in F2 female rats 1299960
qtl_general measurement method: polyethylene catheters were inserted in the carotid artery and blood was drawn 1299960
qtl_general number of animals used: 5-6 months old 266 F2 rats 1299960
qtl_general software used: one-way analysis of variance (ANOVA) 1299960
qtl_map QTL is syntenic to a human familial combined hyperlipidemia (FCHL) QTL identified in Finnish patients 1299960