Cm3 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Cm3 (Cardiac mass QTL 3) Rattus norvegicus

Symbol: Cm3
Name: Cardiac mass QTL 3
RGD ID: 1300150
Previously known as: Specialized Center of Research QTL 117; SCOR117
Trait: heart mass   (VT:0007028)    
Measurement Type: heart weight to body weight ratio   (CMO:0000074)    
LOD Score: 3.97
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2854,237,814 - 55,523,877RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0858,425,679 - 59,716,199RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0857,006,953 - 58,297,648RGDRnor5.0
RGSC_v3.4857,308,742 - 58,692,901RGDRGSC3.4
RGSC_v3.1857,327,796 - 58,711,961RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View
Cardiomegaly  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait
heart mass  (IDA)

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Moreno C, etal., Physiol Genomics 2003 Nov 11;15(3):243-57. Epub 2003 Oct 07.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
70889Idh3aisocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha85497169454991085Rat
61846Psma4proteasome 20S subunit alpha 485534043155347893Rat
2347Chrna5cholinergic receptor nicotinic alpha 5 subunit85536979455398526Rat
2351Chrnb4cholinergic receptor nicotinic beta 4 subunit85541837955436967Rat
2345Chrna3cholinergic receptor nicotinic alpha 3 subunit85540198155415012Rat
727879Gldngliomedin85467901554723198Rat
621539Ireb2iron responsive element binding protein 285522808055311613Rat
2400Crabp1cellular retinoic acid binding protein 185513836355159360Rat
2457Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 185455316554580758Rat
1308677Hykkhydroxylysine kinase85531591955339720Rat
1305224Slnsarcolipin85422138954248110Rat
1311533Tnfaip8l3TNF alpha induced protein 8 like 385441350354455648Rat
1309791Sh2d7SH2 domain containing 785491839954930129Rat
1308718Cib2calcium and integrin binding family member 285493026554947157Rat
1307680Ube2q2ubiquitin conjugating enzyme E2 Q285551840255578342Rat
1308228Skic8SKI8 subunit of superkiller complex85510354255120837Rat
1310035Dnaja4DnaJ heat shock protein family (Hsp40) member A485508524655102715Rat
1564186Elmod1ELMO domain containing 185429836354355348Rat
1586163Dmxl2Dmx-like 285474116454884948Rat
708557Acsbg1acyl-CoA synthetase bubblegum family member 185499129455047276Rat
1596097Zc3h15-ps2zinc finger CCCH-type containing 15, pseudogene 285538506155386940Rat
7556443Ptbp1-ps2polypyrimidine tract binding protein 1, pseudogene 285476481654771085Rat
9399090LOC103693097uncharacterized LOC10369309785455011854564648Rat
41140541LOC120094446small nucleolar RNA SNORD113/SNORD114 family85468644754686527Rat
41285356Ndufb4-ps5NADH:ubiquinone oxidoreductase subunit B4, pseudogene 585521356055213943Rat
41142933LOC120094165uncharacterized LOC12009416585459284854609628Rat
41116915LOC120094166uncharacterized LOC12009416685541281355497821Rat
41290367LOC120094162uncharacterized LOC12009416285426655954267447Rat
41013761LOC120094479small nucleolar RNA SNORA4885442900954429149Rat
41046688Rpl37a-ps8ribosomal protein L37A, pseudogene 885464959754654282Rat
41037667LOC120094163uncharacterized LOC12009416385426746054273668Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10354D8Bord123085541543055415660Ratregion
33880D8Mit1212485489451654894646Ratregion
36161D8Rat3617085423764454237814Ratregion
40544D8Rat15539085507052455070905Ratregion
42223D8Arb1239085458029854580749Ratregion
41454D8Rat14913985552387755524028Ratregion
41472D8Rat15620185434587054346093Ratregion
44423D8Got8617485519068555190859Ratregion
44423D8Got8617485519075355190859Ratregion
44425D8Got8325985532844655328691Ratregion
44426D8Got8526285494990154950163Ratregion
1631160D8Wox3016585541543255415597Ratregion
1631837D8Wox1685458049854580715Ratregion
1634113D8Wox2922685541735855417584Ratregion
7192338Crabp165485515146055152114Ratregion
7193074Chrnb422785541775955417987Ratregion
5036125Crabp117385515201155152184Ratregion
5038884RH12738822085424784854248068Ratregion
5035528Clom27185472226254722533Ratregion
5027383AV35821311185510172255101833Ratregion
5035254AA87502510985515914555159254Ratregion
5025350RH12797520585499070054990905Ratregion
5056357RH14433118985530883855309027Ratregion
5053801RH14285824285499994055000182Ratregion
5053961RH14295022185531086855311089Ratregion
5048684RH13304620185455302754553228Ratregion
5047608RH13242521785499146254991679Ratregion
5049580RH13356221685493029754930513Ratregion
5043468RH13004220485534758455347788Ratregion
5041464RH12887118785455512154555308Ratregion
5072530RH13690320985429857254298781Ratregion
5066390AU04838520885527488455275092Ratregion
5064936BE10872121185540169155401902Ratregion
5066462AU04834213285517532555175457Ratregion
5066518AU04830912885533935255339482Ratregion
5061590BF39677123585509174055091975Ratregion
5086961BQ19412716085490193754902097Ratregion
5086119Chrnb422785542327355424861Ratregion
5087556PMC312758P410585543725055437355Ratregion
5090521AU04980118485497014954970333Ratregion
5085183AA79957014885510138655101534Ratregion
5086596Chrna510485539746955397573Ratregion
5086697AA95745110185499016954990270Ratregion
5502699IREB248785529881555299302Ratregion
5504944AY07488738585534005455340439Ratregion
5506025UniSTS:49748482585501021655011041Ratregion
5500013UniSTS:23613726485510146655101730Ratregion
5502347RH1245608285499018754990269Ratregion
Position Markers

Flank 1: (D8Rat149)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2855,523,877 - 55,524,028 (+)MAPPER
Rnor_6.0859,716,199 - 59,716,349NCBI
Rnor_5.0858,297,648 - 58,297,798UniSTS
RGSC_v3.4858,692,901 - 58,693,265RGD
RGSC_v3.4858,692,907 - 58,693,057UniSTS
RGSC_v3.1858,711,961 - 58,712,111RGD
Celera855,008,447 - 55,008,597UniSTS
RH 3.4 Map8614.2RGD
RH 3.4 Map8614.2UniSTS
RH 2.0 Map8480.2RGD
SHRSP x BN Map840.33RGD
Cytogenetic Map8q24UniSTS
Peak: (D8Rat159)
Rat AssemblyChrPosition (strand)Source
RH 3.4 Map8458.3RGD
RH 3.4 Map8458.3UniSTS
RH 2.0 Map8373.8RGD
SHRSP x BN Map835.78RGD
Flank 2: (D8Rat36)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2854,237,644 - 54,237,814 (+)MAPPER
Rnor_6.0858,425,510 - 58,425,679NCBI
Rnor_5.0857,006,784 - 57,006,953UniSTS
RGSC_v3.4857,308,572 - 57,308,742RGD
RGSC_v3.4857,308,573 - 57,308,742UniSTS
RGSC_v3.1857,327,627 - 57,327,796RGD
RH 3.4 Map8589.1UniSTS
RH 3.4 Map8589.1RGD
RH 2.0 Map8457.2RGD
SHRSP x BN Map841.2RGD
FHH x ACI Map848.36RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)82720571554998217Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815458482492Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300150Cm3Cardiac mass QTL 33.97heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)85423781455523877Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Cm3

RGD Curation Notes
Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at Genomic Map of Cardiovascular Phenotypes 727992
qtl_general heart weight in grams divided by body weight 727992