Bp190 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp190 (Blood pressure QTL 190) Rattus norvegicus

Symbol: Bp190
Name: Blood pressure QTL 190
RGD ID: 1300118
Previously known as: Specialized Center of Research QTL 6; SCOR6
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: blood pressure measurement   (CMO:0000003)    
LOD Score: 2.94
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81588,677,086 - 104,695,021RGD_MAPPER_PIPELINE
mRatBN7.21582,262,520 - 98,288,169RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01589,640,684 - 106,550,657RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.01593,131,834 - 109,944,957RGDRnor_5.0
RGSC_v3.41589,569,706 - 106,177,917RGDRGSC_v3.4
RGSC_v3.11589,585,486 - 106,193,697RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SS/JrHsdMcwi 



Disease Annotations     Click to see Annotation Detail View
hypertension  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
BN/SsNHsd  (IEA)
SS/JrHsdMcwi  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Moreno C, etal., Physiol Genomics 2003 Nov 11;15(3):243-57. Epub 2003 Oct 07.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
402182976LOC134482162small ribosomal subunit protein uS15-like158869959988703783Rat
1592131Tceal8-ps1transcription elongation factor A like 8, pseudogene 1158874120988741832Rat
402079481LOC134482004uncharacterized LOC134482004158881710588826165Rat
2323417Tra2b-ps6transformer 2 beta, pseudogene 6158891213588913253Rat
41035228LOC120096902uncharacterized LOC120096902158896430788966189Rat
1311472Spry2sprouty RTK signaling antagonist 2158910680989111926Rat
1565615Trim52tripartite motif-containing 52158930049589324140Rat
11402272LOC108353046protein transport protein Sec61 subunit gamma pseudogene158941643789416685Rat
1593227Ldha-ps2lactate dehydrogenase A, pseudogene 2158958040889588068Rat
11362115LOC108352964uncharacterized LOC108352964158960607989630329Rat
402173018LOC134482005uncharacterized LOC134482005158964549589676652Rat
41159086LOC120097072uncharacterized LOC120097072158972841989778617Rat
41071279LOC120097270small nucleolar RNA SNORA17158996849489968569Rat
41029775LOC120097309U6 spliceosomal RNA159021385290213956Rat
11393005LOC108353047uncharacterized LOC108353047159075201390763832Rat
2323174Psmd8-ps2proteasome 26S subunit, non-ATPase 8, pseudogene 2159082397890824759Rat
41315848LOC120097074uncharacterized LOC120097074159095704090976439Rat
402431717LOC134482006endogenous retrovirus group K member 19 Env polyprotein-like159099268490997025Rat
2323017LOC100363428PCNA-associated factor-like159102476491026730Rat
9187193Ftl1l3ferritin light chain 1 like 3159124914091249574Rat
7590644Gapdh-ps105Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 105159150877991509704Rat
7536491Envl-ps8MLV-related proviral Env polyprotein-like, pseudogene 8159175093191752871Rat
41266332LOC120097278U2 spliceosomal RNA159179288891793014Rat
1308858Slitrk1SLIT and NTRK-like family, member 1159213770392141741Rat
2319521Apool-ps2apolipoprotein O-like, pseudogene 2159303039593031399Rat
41341524LOC120097269small nucleolar RNA SNORA17159316813193168247Rat
402173479LOC134482007uncharacterized LOC134482007159356701493596738Rat
402211423LOC134482009uncharacterized LOC134482009159359678893614405Rat
402120492LOC134482008uncharacterized LOC134482008159364613893652320Rat
2323641Hnrnpa1-ps27heterogeneous nuclear ribonucleoprotein A1, pseudogene 27159379080793791605Rat
1306550Slitrk6SLIT and NTRK-like family, member 6159397781293984431Rat
2319369Wdr12-ps2WD repeat domain 12, pseudogene 2159411105794112749Rat
41022417Eif4a2-ps1eukaryotic translation initiation factor 4A2, pseudogene 1159436739594370608Rat
402136365LOC134482010uncharacterized LOC134482010159449313894548675Rat
41380823St13-ps4ST13, Hsp70 interacting protein, pseudogene 4159461641294624740Rat
11455629LOC108352970uncharacterized LOC108352970159462721694748465Rat
402291381LOC134482011uncharacterized LOC134482011159484787894850164Rat
402322366LOC134482070large ribosomal subunit protein uL29-like159495533994956073Rat
41352702LOC120097077uncharacterized LOC120097077159500270195035156Rat
1559833Rpl5-ps10ribosomal protein L5, pseudogene 10159511395295115236Rat
41155398LOC120097076uncharacterized LOC120097076159522245495233323Rat
402134974LOC134482012uncharacterized LOC134482012159523328095247411Rat
1310957Slitrk5SLIT and NTRK-like family, member 5159526139795270465Rat
41238556LOC120097315U6 spliceosomal RNA159561057095610673Rat
11513546LOC108352971uncharacterized LOC108352971159561148095886402Rat
41401429Trnaa-agc65transfer RNA alanine (anticodon AGC) 65159614086096140934Rat
1592125C16h19orf44-ps1similar to human chromosome 19 open reading frame 44, pseudogene 1159617024996171371Rat
41301829LOC120097284U2 spliceosomal RNA159643875896438940Rat
402135272LOC134482013uncharacterized LOC134482013159654739996548323Rat
11467873Sec61gl3SEC61 translocon subunit gamma like 3159657586396576069Rat
2316379Vom1r-ps104vomeronasal 1 receptor pseudogene 104159705140197052282Rat
1592124Nsa2-ps8NSA2 ribosome biogenesis factor, pseudogene 8159732438197325263Rat
7613297LOC102547440uncharacterized LOC102547440159737056697463360Rat
41039265LOC120097078uncharacterized LOC120097078159746346097504265Rat
402315024LOC134482071poly(rC)-binding protein 2-like159759029697591048Rat
11501014LOC108352972uncharacterized LOC108352972159759299197629776Rat
41010480LOC120097305U6 spliceosomal RNA159759762397597729Rat
7551051LOC102547827uncharacterized LOC102547827159765328297680669Rat
402151561LOC134482014uncharacterized LOC134482014159772065697824418Rat
1592123Rps11-ps11ribosomal protein S11, pseudogene 11159786628397866822Rat
11510082LOC10835301240S ribosomal protein S17 pseudogene159815836598167861Rat
41046097LOC120097080uncharacterized LOC120097080159840253798423490Rat
2325600Mir17microRNA 17159858784898587931Rat
2325396Mir18amicroRNA 18a159858798498588079Rat
2325462Mir19amicroRNA 19a159858813198588212Rat
2325401Mir20amicroRNA 20a159858830398588387Rat
2325433Mir19b1microRNA 19b-1159858843398588519Rat
2325390Mir92a1microRNA 92a-1159858855598588632Rat
1308835Gpc5glypican 51598614499100051285Rat
7644006LOC102548462uncharacterized LOC102548462159861746598648445Rat
7517571LOC10254836940S ribosomal protein S16-like159866692098667428Rat
402339913LOC134482015uncharacterized LOC134482015159919534899212716Rat
402308411LOC134482016uncharacterized LOC134482016159965122199654080Rat
41229299LOC120097209small nucleolar RNA SNORA70159982502099825154Rat
6488688LOC10091213260S ribosomal protein L10-like159982520399829530Rat
41338783LOC120097306U6 spliceosomal RNA159991258199912687Rat
1593308Gpc6glypican 615100437415101435038Rat
41007823LOC120097177uncharacterized LOC12009717715100511069100525118Rat
402313366LOC134482019uncharacterized LOC13448201915100524645100543304Rat
402144661LOC134482018uncharacterized LOC13448201815100739851100801798Rat
9231101Tmem11-ps1transmembrane protein 11, pseudogene 115100856415100857345Rat
11394812LOC10835302940S ribosomal protein S6 pseudogene15100887110100895361Rat
9449268LOC103693782uncharacterized LOC10369378215100936419100947643Rat
402013740LOC134482017importin-5-like15101087529101144149Rat
1564975Dctdopachrome tautomerase15101469159101508029Rat
7620398LOC102548872uncharacterized LOC10254887215101521884101530026Rat
402256748LOC134482231uncharacterized LOC13448223115101537416101539643Rat
402377250LOC134482232uncharacterized LOC13448223215101545058101548916Rat
402045426LOC134482233uncharacterized LOC13448223315101549583101550223Rat
7735776LOC102548945uncharacterized LOC10254894515101559261101569557Rat
11492158Trnaf-gaa5transfer RNA phenylalanine (anticodon GAA) 515101560488101560560Rat
1306544TgdsTDP-glucose 4,6-dehydratase15101581765101602779Rat
1359193Gpr180G protein-coupled receptor 18015101602870101635556Rat
402441509LOC134482020uncharacterized LOC13448202015101673841101675212Rat
1304724Sox21SRY-box transcription factor 2115101699580101703175Rat
7654866LOC102549101uncharacterized LOC10254910115101761250101769377Rat
40937839LOC120097261small nucleolar RNA SNORA1715101769920101770026Rat
9095740LOC103693790uncharacterized LOC10369379015101802195101824859Rat
402237386LOC134482021uncharacterized LOC13448202115101835193101845473Rat
620266Abcc4ATP binding cassette subfamily C member 415101948387102182912Rat
41363845LOC120097318U6 spliceosomal RNA15102054171102054274Rat
41192109LOC120097081uncharacterized LOC12009708115102075247102093907Rat
41059821LOC120097082uncharacterized LOC12009708215102246913102251149Rat
41163671LOC120097255small nucleolar RNA SNORA1715102251470102251603Rat
1308027Cldn10claudin 1015102269858102361589Rat
1307701Dzip1DAZ interacting zinc finger protein 115102363392102417085Rat
708518Dnajc3DnaJ heat shock protein family (Hsp40) member C315102432667102475643Rat
41023110S100a10-ps1S100 calcium binding protein A10, pseudogene 115102436813102437374Rat
1563520Uggt2UDP-glucose glycoprotein glucosyltransferase 215102480239102646291Rat
41032975LOC120097083uncharacterized LOC12009708315102646299102648671Rat
1305888Hs6st3heparan sulfate 6-O-sulfotransferase 315102688420103407725Rat
41303432LOC120097180uncharacterized LOC12009718015102763472102787893Rat
41340417LOC120097294U6 spliceosomal RNA15103088603103088709Rat
7499911LOC102546571uncharacterized LOC10254657115103154426103209676Rat
41031812LOC120097179uncharacterized LOC12009717915103342676103358902Rat
11416357LOC108352977uncharacterized LOC10835297715103453011103471320Rat
402098125LOC134482022uncharacterized LOC13448202215103494082103502068Rat
1592106Gapdhl5glyceraldehyde-3-phosphate dehydrogenase like 515103534566103536831Rat
1594175Zcchc9-ps1zinc finger CCHC-type containing 9, pseudogene 115103547372103548264Rat
1303155Oxgr1oxoglutarate receptor 115103551338103573611Rat
11433702LOC108352979uncharacterized LOC10835297915103556663103562588Rat
41241680LOC120097084uncharacterized LOC12009708415103620095103646030Rat
402177895LOC134482023uncharacterized LOC13448202315103632622103633667Rat
7563047LOC102547244uncharacterized LOC10254724415103658661103676811Rat
7609495LOC102551086uncharacterized LOC10255108615103702074103709544Rat
41353381LOC120097085uncharacterized LOC12009708515103717329103727030Rat
1591755Mbnl2muscleblind-like splicing regulator 215103792134103949827Rat
40955435LOC120097086uncharacterized LOC12009708615103879626103895814Rat
41062514LOC120097087uncharacterized LOC12009708715103932719103935317Rat
41347773LOC120097088uncharacterized LOC12009708815103997772104002440Rat
620590Rap2aRAP2A, member of RAS oncogene family15104003744104004234Rat
41052703LOC120097090uncharacterized LOC12009709015104092599104094772Rat
11423500LOC108352981uncharacterized LOC10835298115104216510104276315Rat
402297558LOC134482024uncharacterized LOC13448202415104289132104290028Rat
1308715Ipo5importin 515104397626104447985Rat
2323549Rps7-ps12ribosomal protein S7, pseudogene 1215104468741104469406Rat
402158550LOC134482234uncharacterized LOC13448223415104488967104490139Rat
6501347LOC100909886uncharacterized LOC10090988615104497918104501362Rat
1305346Farp1FERM, ARH/RhoGEF and pleckstrin domain protein 115104531196104770148Rat
402256343LOC134482025uncharacterized LOC13448202515104633877104637917Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
33820D15Mit6210159777307497773284Ratregion
34160D15Mgh510815101425275101425383Ratregion
34162D15Mgh621815102247388102247606Ratregion
34409D15Mgh9158158867708688677244Ratregion
36149D15Rat26147159875413498754281Ratregion
37534D15Rat4911415103726827103726941Ratregion
37014D15Rat2413015100848961100849091Ratregion
39868D15Rat10514615103087266103087412Ratregion
40490D15Rat12724815101544844101545092Ratregion
40516D15Rat10621415104694807104695021Ratregion
40064D15Rat103121159888591898886039Ratregion
40312D15Rat100127158878641288786539Ratregion
39324D15Rat5123615100796923100797159Ratregion
39570D15Rat10423715100571077100571314Ratregion
43057D15Rat153226159131963791319863Ratregion
43058D15Rat154233158899136688991599Ratregion
43059D15Rat155240159944077999441019Ratregion
43062D15Rat12824615103898776103899022Ratregion
45295D15Got9229215103020841103021133Ratregion
1640262D15Got2419115103296154103296245Ratregion
5050450RH13406320115104009967104010168Ratregion
5052733RH14224114915103949575103949724Ratregion
5502639RH12606670115104446079104446780Ratregion
152025252rs645279520159267151792671517Ratregion
Position Markers

Flank 1: (D15Mgh9)
Rat AssemblyChrPosition (strand)Source
GRCr81588,677,086 - 88,677,244 (+)Marker Load Pipeline
mRatBN7.21582,262,520 - 82,262,678 (+)MAPPER
Rnor_6.01589,640,684 - 89,640,841NCBI
Rnor_5.01593,131,834 - 93,131,991UniSTS
RGSC_v3.41589,569,706 - 89,569,864RGD
RGSC_v3.41589,569,707 - 89,569,864UniSTS
Celera1581,377,978 - 81,378,135UniSTS
RGSC_v3.11589,585,486 - 89,585,644RGD
SHRSP x BN Map1552.8498UniSTS
SHRSP x BN Map1552.8498RGD
Cytogenetic Map15q22UniSTS
Peak: (D15Rat106)
Rat AssemblyChrPosition (strand)Source
GRCr815104,694,807 - 104,695,021 (+)Marker Load Pipeline
mRatBN7.21598,287,955 - 98,288,169 (+)MAPPER
Rnor_6.015106,550,444 - 106,550,657NCBI
Rnor_5.015109,944,744 - 109,944,957UniSTS
RGSC_v3.415106,177,703 - 106,177,917RGD
RGSC_v3.415106,177,704 - 106,177,917UniSTS
Celera1597,072,390 - 97,072,603UniSTS
RGSC_v3.115106,193,484 - 106,193,697RGD
RH 3.4 Map15688.5UniSTS
RH 3.4 Map15688.5RGD
SHRSP x BN Map1565.3898UniSTS
SHRSP x BN Map1565.3898RGD
FHH x ACI Map1574.04RGD
Cytogenetic Map15q24-q25UniSTS
Flank 2: (D15Rat106)
Rat AssemblyChrPosition (strand)Source
GRCr815104,694,807 - 104,695,021 (+)Marker Load Pipeline
mRatBN7.21598,287,955 - 98,288,169 (+)MAPPER
Rnor_6.015106,550,444 - 106,550,657NCBI
Rnor_5.015109,944,744 - 109,944,957UniSTS
RGSC_v3.415106,177,703 - 106,177,917RGD
RGSC_v3.415106,177,704 - 106,177,917UniSTS
Celera1597,072,390 - 97,072,603UniSTS
RGSC_v3.115106,193,484 - 106,193,697RGD
RH 3.4 Map15688.5UniSTS
RH 3.4 Map15688.5RGD
SHRSP x BN Map1565.3898UniSTS
SHRSP x BN Map1565.3898RGD
FHH x ACI Map1574.04RGD
Cytogenetic Map15q24-q25UniSTS


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1582194914108192169Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1574735564106469153Rat
1300118Bp190Blood pressure QTL 1902.94arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1588677086104695021Rat
1358354Srcrt5Stress Responsive Cort QTL 53.38blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1582503470108192169Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1582714037106778197Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
1300120Kidm7Kidney mass QTL 73.55kidney mass (VT:0002707)left kidney wet weight to body weight ratio (CMO:0001954)1588677086104695021Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
7411646Foco21Food consumption QTL 2123.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1584278281108192169Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1572716871101425383Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)1561710951106710951Rat
1581519Cm59Cardiac mass QTL 592.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1595260808102247606Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1575928947101425383Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1559257087104257087Rat
2313080Bss65Bone structure and strength QTL 653.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1567399137108192169Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1582194914108192169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)1560213984105213984Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
61477Aia4Adjuvant induced arthritis QTL 43joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)156244089297773284Rat
70182BpQTLcluster12Blood pressure QTL cluster 123.53arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)1572716871101425383Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1564571127108192169Rat
1641889Colcr6Colorectal carcinoma resistance QTL 62.90.0126intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1583700787108192169Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Bp190

RGD Curation Notes
Note Type Note Reference
qtl_general additional information, including phenotype and mapping information, can be found at Genomic Map of Cardiovascular Phenotypes 727992
qtl_general blood pressure, high salt, day 1, mean of 3 hour blood pressure recording (SCOR6) 727992