BW17_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: BW17_H (Body weight QTL 17 (human)) Homo sapiens

Symbol: BW17_H
Name: Body weight QTL 17 (human)
RGD ID: 1299997
Trait: Body weight
Measurement Type: body mass index
LOD Score: 1.5
P Value: Not Available
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372046,551,982 - 55,514,427RGDGRCh37
Build 362045,985,389 - 54,947,834RGDNCBI36
Build 342045,885,334 - 55,047,865RGD
Population Stats: European American and African American families with Body mass index >27



Disease Annotations     Click to see Annotation Detail View
obesity  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome. Baguhl R, etal., Obesity (Silver Spring). 2009 Jun;17(6):1215-9. Epub 2009 Feb 19.
2. Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity. Dong C, etal., Am J Hum Genet 2003 Jan;72(1):115-24. Epub 2002 Dec 11.
Related QTLs

Related QTL Description Reference
Slep7 maps to syntenic region RGD:2312642
Scl63 maps to syntenic region RGD:2312642
Bw94 maps to syntenic region RGD:2312642


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D20S178)
Human AssemblyChrPosition (strand)Source
GRCh372046,551,982 - 46,552,235UniSTS
Build 362045,985,389 - 45,985,642RGD
Celera2043,255,532 - 43,255,783RGD
Cytogenetic Map20q12-q13.1UniSTS
HuRef2043,299,579 - 43,299,830UniSTS
Marshfield Genetic Map2066.16UniSTS
Marshfield Genetic Map2066.16RGD
Genethon Genetic Map2065.5UniSTS
deCODE Assembly Map2073.83UniSTS
Whitehead-RH Map20309.6UniSTS
Whitehead-YAC Contig Map20 UniSTS
Flank 2: (D20S149)
Human AssemblyChrPosition (strand)Source
GRCh372055,514,140 - 55,514,427UniSTS
Build 362054,947,547 - 54,947,834RGD
Celera2052,254,483 - 52,254,770RGD
HuRef2052,295,947 - 52,296,242UniSTS
Marshfield Genetic Map2086.98UniSTS
Marshfield Genetic Map2086.98RGD
TNG Radiation Hybrid Map2025667.0UniSTS
Stanford-G3 RH Map202728.0UniSTS
NCBI RH Map20572.7UniSTS


Additional Information

Database Acc Id Source(s)
NCBI Gene BW17_H
OMIM 601665

RGD Curation Notes
Note Type Note Reference
qtl_population European American and African American families with Body mass index >27 738100
qtl_population_details 200 European American families with 542 siblings and 44 African American families with 125 siblings. Sibship size ranged from two to nine in European families and from two to eight in African American families 738100
qtl_statistics NPL score: 2.25(Body mass index) NPL score: 2.57(percent body fat) 738100
qtl_statistics_details Conditional analysis for BMI, weighted by evidence of linkage at 10q, showed an increase in LOD score at 20q from 1.53 (baseline) to 2.80 738100