BP10_H QTL Report (Homo sapiens) - Rat Genome Database

Name: BP10_H
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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QTL Registration

General

QTL: BP10_H (Blood pressure QTL 10 (human)) Homo sapiens

Symbol:

BP10_H

Name:

Blood pressure QTL 10 (human)

RGD ID:

1298483

Trait:

Blood pressure

Measurement Type:

diastolic

LOD Score:

3.92

P Value:

Not Available

Variance:

Not Available

Position

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	2	72,075,436 - 98,075,436	RGD_MAPPER_PIPELINE	GRCh37
Build 36	2	71,928,947 - 97,928,947	RGD	NCBI36
Build 34	2	69,886,938 - 99,886,938	RGD

Population Stats:

Mexican-American families selected without regard to blood pressure status

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypertension (IDA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Elevated mean arterial pressure (QTM)

References

References - curated

#	Reference Title	Reference Citation
1.	Genome-wide linkage analysis of blood pressure in Mexican Americans.	Atwood LD, etal., Genet Epidemiol 2001 Apr;20(3):373-82.
2.	Differential genetic basis for pre-menopausal and post-menopausal salt-sensitive hypertension.	Herrera VL, etal., PLoS One. 2012;7(8):e43160. doi: 10.1371/journal.pone.0043160. Epub 2012 Aug 17.

Related QTLs

Related QTL	Description	Reference
Bp390	maps to syntenic region	RGD:10755344

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Peak: (D2S1790)

Human Assembly	Chr	Position (strand)	Source
GRCh37	2	85,075,289 - 85,075,583	UniSTS
Build 36	2	84,928,800 - 84,929,094	RGD
Celera	2	84,904,067 - 84,904,357	RGD
Cytogenetic Map	2	p11.2	UniSTS
HuRef	2	84,971,283 - 84,971,569	UniSTS
TNG Radiation Hybrid Map	2	53278.0	UniSTS
Stanford-G3 RH Map	2	3524.0	UniSTS
Whitehead-RH Map	2	375.4	UniSTS
Whitehead-YAC Contig Map	2		UniSTS
NCBI RH Map	2	460.4	UniSTS

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	BP10_H

RGD Curation Notes

Note Type	Note	Reference
qtl_population	Mexican-American families selected without regard to blood pressure status	738133
qtl_population_details	population-based sample of ten Mexican American families(637 individuals, 495 with blood pressure data) in the San Antonio Heart Study in which probands are 50-60 yrs, have a participating spouse, have at least 6 first degree relatives excluding parents in the San Antonio area, selected without regard to blood pressure status	738133
qtl_statistics_details	two-point linkage analysis was carried out using computer program PAP (Pedigree Analysis Package) v.4 under a single-locus two-allele Mendelian model that incorpporates sex-and genotype-specific effects of age, body mass index, and alternate blood pressure measures	738133

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: BP10_H (Blood pressure QTL 10 (human)) Homo sapiens

Manual Human Phenotype Annotations - RGD