Am3 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Am3 (Aortic mass QTL 3) Rattus norvegicus

Symbol: Am3
Name: Aortic mass QTL 3
RGD ID: 12879843
Previously known as: BpcakmC2QTL3
Trait: aorta mass   (VT:0002845)    
Measurement Type: aorta weight to aorta length to body weight ratio   (CMO:0002722)    
LOD Score: Not Available
P Value: 0.016
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22142,323,368 - 146,786,035RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0227,161,361 - 148,295,267RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.0246,277,412 - 167,706,439RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.42147,424,195 - 152,050,550RGD_MAPPER_PIPELINERGSC_v3.4
Cross Type: Not Available
Strains Crossed: SS.MNS-(D2Chm51-D2Rat341)/Ayd 



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Experimental Condition

Measurement Method

Vertebrate Trait
aorta mass  (IDA)

Rat Strain

References

References - curated
# Reference Title Reference Citation
1. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (D2Chm90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22142,323,368 - 142,323,610 (+)MAPPER
Rnor_6.02148,295,267 - 148,295,508NCBI
Rnor_5.02167,706,439 - 167,706,680UniSTS
RGSC_v3.42147,424,195 - 147,424,436UniSTS
Celera2136,755,765 - 136,756,448UniSTS
Celera2136,755,765 - 136,755,986UniSTS
Cytogenetic Map2 RGD
Flank 2: (D2Chm46)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22146,785,831 - 146,786,035 (+)MAPPER
Rnor_6.0227,161,158 - 27,161,361NCBI
Rnor_5.0246,277,209 - 46,277,412UniSTS
RGSC_v3.42152,050,347 - 152,050,550UniSTS
Celera2141,125,225 - 141,125,402UniSTS
Cytogenetic Map2q31UniSTS


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-03 Am3  Aortic mass QTL 3  Am3  Cardiac mass QTL 88  Symbol and/or name change 68913 APPROVED

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 8 gender: male 1599557
qtl_general also affects heart left ventricle mass, kidney mass, heart mass and blood pressure, but has no effect on body mass or heart right ventricle mass 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age, at 14 weeks animals were decapitated, organs removed, blotted and weighed 1599557
qtl_trait_method aorta section was from the diaphragm to the first intercostal artery 1599557