Bp401 QTL Report (Rattus norvegicus) - Rat Genome Database
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QTL: Bp401 (Blood pressure QTL 401) Rattus norvegicus

Symbol: Bp401
Name: Blood pressure QTL 401
RGD ID: 12879477
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01342,155,543 - 44,588,509RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01347,267,053 - 92,267,053RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41338,329,089 - 83,329,089RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.BN-(D13Rat20-D13Got22)/Mcwi SS.BN-(D13Rat111-D13Hmgc85)/Mcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Tmem163 is a candidate Gene for Bp401
Nckap5 is a candidate Gene for Bp401

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain

References


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1306745Gpr39G protein-coupled receptor 39134200864242220737Rat
1549754Lypd1Ly6/Plaur domain containing 1134221988442263024Rat
1564507Nckap5NCK-associated protein 5134226587543049232Rat
1592076LOC304754similar to Proteasome activator complex subunit 2 (Proteasome activator 28-beta subunit) (PA28beta) (PA28b) (Activator of multicatalytic protease subunit 2) (11S regulator complex beta subunit) (REG-beta)134307951243080402Rat
1560333RGD1560333similar to Ferritin light chain (Ferritin L subunit)134338499943385544Rat
1563709RGD1563709similar to K-ALPHA-1 protein134340127343402677Rat
1589434LOC680642similar to cysteine and glycine-rich protein 2134346528143475972Rat
11417017LOC108352524cysteine and glycine-rich protein 2 pseudogene134347269443476059Rat
11459344LOC108352525uncharacterized LOC108352525134350746243511464Rat
2325611Mir350microRNA 350134382749243827590Rat
620100Mgat5alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase134385074444157860Rat
1306212Tmem163transmembrane protein 163134416630644345735Rat
620868Acmsdaminocarboxymuconate semialdehyde decarboxylase134442468944468734Rat
11509631LOC108352526uncharacterized LOC108352526134446975144475881Rat
1309205Ccnt2cyclin T2134447595944516892Rat
1566400Map3k19mitogen-activated protein kinase kinase kinase 19134452405544553197Rat
1306487Rab3gap1RAB3 GTPase activating protein catalytic subunit 1134457820844649876Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
34351D13Mgh4150134231074442310885Ratregion
37804D13Rat80245134290754342907801Ratregion
36695D13Rat38156134255241442552540Ratregion
36747D13Rat20138134215554342155682Ratregion
36767D13Rat40164134336609843366261Ratregion
40398D13Rat147258134434265544342914Ratregion
41978D13Arb5213134378572743785939Ratregion
41978D13Arb5213134279472442794936Ratregion
41980D13Arb6150134301300443013161Ratregion
41222D13Rat114145134224634842246476Ratregion
41304D13Rat121125134338921843389346Ratregion
41366D13Rat119205134338402143384231Ratregion
42988D13Rat174235134358977743590069Ratregion
45026D13Got6180134228144242281621Ratregion
45027D13Got12299134294449842944692Ratregion
45028D13Got9249134378569343785941Ratregion
45028D13Got9249134279472242794970Ratregion
45029D13Got10145134277024342770387Ratregion
45030D13Got13234134325163343251866Ratregion
45031D13Got14163134365372543653887Ratregion
45033D13Got11238134410079844101035Ratregion
45034D13Got18180134414519644145375Ratregion
67818D13Uwm6236134371760543717846Ratregion
67818D13Uwm6236134286171542861956Ratregion
1582022D13Hmgc60124134373423943734362Ratregion
1582022D13Hmgc60124134284651742846640Ratregion
2324933D13Hmgc40258134393830543938562Ratregion
2324933D13Hmgc40258134354597743546234Ratregion
2324935D13Hmgc72195134247972842479922Ratregion
2324937D13Hmgc93173134230173242301904Ratregion
2324939D13Hmgc85151134458835744588509Ratregion
5037037AU050004114134244464242444755Ratregion
5032335AI853408118134222018442220301Ratregion
5033201RH137955147134222149942221645Ratregion
5033589RH13937996134360686043606955Ratregion
5059288BF387978180134408193344082112Ratregion
5045096RH130981180134451659344516772Ratregion
5045448RH131184185134416189544162079Ratregion
5045302RH131100190134447007544470264Ratregion
5039744RH127882187134451464644514832Ratregion
5079378RH140961192134451237444512565Ratregion
5076236RH139058120134416639444166513Ratregion
5072106RH136654183134434921544349397Ratregion
5066596AU048264136134227874942278884Ratregion
5066848AU048115164134266859342668755Ratregion
5068446AU047140128134230938442309508Ratregion
5068884AU046866236134215663042156860Ratregion
5069586AU046399267134336076343361026Ratregion
5065536BE115808183134381619143816373Ratregion
5065540BE115809153134451330644513458Ratregion
5060402BI292164159134392268743922845Ratregion
5060402BI292164159134356138343561541Ratregion
5061426BF396392130134384358243843711Ratregion
5081683BF41457692134221223342212324Ratregion
5085118BQ196234162134415919244159353Ratregion
5088957AU048869132134278091342781044Ratregion
5080944RH141873210134447847744478686Ratregion
5086392BQ205581177134383268143832857Ratregion
5085880BQ198886158134451476544514922Ratregion
5505532STS-Z411431080134393758443938663Ratregion
5505532STS-Z411431080134354587643546955Ratregion
5500707RH71322171134308019443080364Ratregion
Position Markers

Flank 1: (D13Rat20)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01342,155,543 - 42,155,682NCBI
Rnor_5.01347,267,053 - 47,267,192UniSTS
RGSC_v3.41338,329,089 - 38,329,229RGD
RGSC_v3.41338,329,090 - 38,329,229UniSTS
RGSC_v3.11338,343,132 - 38,343,272RGD
Celera1337,065,270 - 37,065,412UniSTS
RH 2.0 Map13292.2RGD
SHRSP x BN Map138.0099RGD
FHH x ACI Map139.15RGD
Cytogenetic Map13q11UniSTS
Flank 2: (D13Hmgc85)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01344,588,357 - 44,588,509NCBI
Celera1339,740,890 - 39,741,040UniSTS
Cytogenetic Map13q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13147622148Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13901674250513953Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131409633059096330Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131409633059096330Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131444158250799665Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131444158251577031Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131981081464810814Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)132005247765052477Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132148248158537177Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
2303030Bp327Blood pressure QTL 327arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133530126346444796Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133614753364868393Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61453Pur1Proteinuria QTL 118.06total urine protein amount (VT:0000032)urine protein level (CMO:0000591)133937292742310885Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
2292232Pur16Proteinuria QTL 1617.2total urine protein amount (VT:0000032)urine protein level (CMO:0000591)134106005747227923Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134215554344588509Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cand_genes Hypothetical protein-coding loci LOC68052 and LOC501853 are also potential candidate genes 12798539
qtl_related_qtls Bp327 1625678
qtl_trait Brown Norway alleles attenuate hypertension and proteinuria (only male rats used) 12798539
qtl_trait_method measurement method: mean arterial pressure was measured in congenic strain male rats on days 3, 7, 14 and 21 of 8% NaCl diet. Urine protein was measured on days 7, 14 and 21 of 8% NaCl diet 12798539