Bp395 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp395 (Blood pressure QTL 395) Rattus norvegicus

Symbol: Bp395
Name: Blood pressure QTL 395
RGD ID: 12879436
Also known as: Line9BP1
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: mean arterial blood pressure   (CMO:0000009)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21344,639,182 - 45,700,190RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01349,994,708 - 51,081,193RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01355,063,057 - 56,136,528RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41346,103,036 - 47,198,372RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.BN-(D13Rat25-RN34_13048990782)/Mcwi 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Ren is a candidate Gene for Bp395
Mybph is a candidate Gene for Bp395
Chit1 is a candidate Gene for Bp395
Plekha6 is a candidate Gene for Bp395

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Vertebrate Trait

Rat Strain

References

References - curated
1. Flister MJ, etal., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2048Adora1adenosine A1 receptor134565887245695821Rat
620287Mybphmyosin binding protein H134565315645660893Rat
727850Kiss1KiSS-1 metastasis-suppressor134477482344780707Rat
1304916Optcopticin134535395445368254Rat
621305Atp2b4ATPase plasma membrane Ca2+ transporting 4134515613745255292Rat
620874Chi3l1chitinase 3 like 1134564180245649787Rat
620226Prelpproline and arginine rich end leucine rich repeat protein134536840745391480Rat
3554Renrenin134479626044807491Rat
2225Btg2BTG anti-proliferation factor 2134553188145535642Rat
1305646Chit1chitinase 1134556584145613593Rat
1305304Etnk2ethanolamine kinase 2134481122444829037Rat
1308290Zc3h11azinc finger CCCH-type containing 11A134507342245113901Rat
1309674Sox13SRY-box transcription factor 13134483109744875522Rat
1561566LOC498231LRRGT00144134504849845067460Rat
1563522Lax1lymphocyte transmembrane adaptor 1134513482545145381Rat
1566310Golt1agolgi transport 1A134476035644773123Rat
1564395Plekha6pleckstrin homology domain containing A6134461474044754951Rat
619769Fmodfibromodulin134549351745504134Rat
2321675Snrpesmall nuclear ribonucleoprotein polypeptide E134505098645057231Rat
7501983LOC102550525uncharacterized LOC102550525134480077244802578Rat
7514622LOC102557118uncharacterized LOC102557118134538044245384435Rat
7633688LOC102552406uncharacterized LOC102552406134561360645636556Rat
9238526Zbed6zinc finger, BED-type containing 6134510748945113141Rat
9461626LOC103692077uncharacterized LOC103692077134492825644937589Rat
11453213LOC108352533uncharacterized LOC108352533134511636845130742Rat
41345153LOC120096248ethanolamine kinase 2-like134481453744829052Rat
41104579LOC120096251uncharacterized LOC120096251134550307245523082Rat
41075572LOC120096249NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10-like134512119745122944Rat
41337984LOC120096250uncharacterized LOC120096250134513631545140254Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
11232D13Arb7317134480209344802410Ratregion
33935D13Mit8206134529565245295858Ratregion
36884D13Rat25166134504940445049579Ratregion
38240D13Rat91172134541775345417941Ratregion
40688D13Rat124236134522835845228590Ratregion
41146D13Rat125235134549782145498068Ratregion
45048D13Wox2147134516231245162453Ratregion
45052D13Got26186134527247045272654Ratregion
60759D13Wox3277134559344745593724Ratregion
60037D13Got28139134536284345363002Ratregion
1627537D13Sunn1090243134521437145214612Ratregion
1627537D13Sunn1090243134521437145214612Ratregion
1642153D13Hmgc03237134568907745689314Ratregion
1642161D13Hmgc30205134569998345700190Ratregion
1642163D13Hmgc84254134463918244639436Ratregion
5034355SHGC-76196150134515803245158182Ratregion
5029377RH144564156134515647945156634Ratregion
5030715BE107718154134525472545254879Ratregion
5051286RH134546185134475472644754911Ratregion
5051623BB17643199134566191445662013Ratregion
5057716BF392626106134469463944694745Ratregion
5053087RH142446178134550370245503880Ratregion
5050744RH134233216134507186145072077Ratregion
5054163RH143066157134523453845234695Ratregion
5052929RH142356151134564955845649709Ratregion
5054389RH143196156134469727144697427Ratregion
5040728RH128449192134566005545660750Ratregion
5041338RH128800210134513487445135084Ratregion
5049302RH133402188134550376545503953Ratregion
5046860RH131996213134565897445659187Ratregion
5046874RH132004187134536845745368644Ratregion
5040296RH128202212134482872744828939Ratregion
5075090RH138392176134480724144807417Ratregion
5080680RH141720211134475249544752706Ratregion
5064976BI302954171134543307945433250Ratregion
5065038BE108977156134484974144849897Ratregion
5070161RH94507185134479589244796082Ratregion
5064196BI296337241134554087645541117Ratregion
5062384BE106626190134564394245644132Ratregion
5064182BE120749197134511202545112222Ratregion
5087297AA819837150134553378245533932Ratregion
5082631BE119883200134471522644715426Ratregion
5087686UniSTS:141040179134566266045662839Ratregion
5081491AA998833156134477295144773108Ratregion
5081909BE118735193134565899445659187Ratregion
5085112AW531798205134561335645613561Ratregion
5506793G45403176134531345545313631Ratregion
5501223PMC156147P1293134553392045534013Ratregion
5501071PMC133870P1417134549623845496655Ratregion
6480500D13Hmgc56200134564255045642750Ratregion
6480492D13Hmgc10178134551471945514897Ratregion
128794684110178134551471945514897Ratregion
Position Markers

Flank 1: (D13Hmgc84)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21344,639,182 - 44,639,436 (+)MAPPER
Rnor_6.01349,994,708 - 49,994,961NCBI
Rnor_5.01355,063,057 - 55,063,310UniSTS
RGSC_v3.41346,103,036 - 46,103,289UniSTS
Celera1344,972,608 - 44,972,861UniSTS
Cytogenetic Map13q13UniSTS
Flank 2: (D13Hmgc30)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21345,699,983 - 45,700,190 (+)MAPPER
Rnor_6.01351,080,989 - 51,081,193NCBI
Rnor_5.01356,136,324 - 56,136,528UniSTS
RGSC_v3.41347,198,168 - 47,198,372UniSTS
Celera1346,028,185 - 46,028,389UniSTS
Cytogenetic Map13 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133124133158363171Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
2303032Bp328Blood pressure QTL 328arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134118402245417941Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134343790447841255Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134372077062022792Rat
12879436Bp395Blood pressure QTL 395arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134463918245700190Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134522835847841255Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general software used: statistics - Sigma Plot 11.0 12802369
qtl_trait Brown Norway alleles attenuate hypertension and albuminuria (only male rats used) 12802369
qtl_trait_method measurement method: mean arterial pressure was measured in congenic strain male rats after 21 days of 8% NaCl diet. Albumin excretion was measured after 17 days of 8% NaCl diet 12802369