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Gene: Abcc1 (ATP binding cassette subfamily C member 1 (ABCC1 blood group)) Chinchilla lanigera

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Symbol:

Abcc1

Name:

ATP binding cassette subfamily C member 1 (ABCC1 blood group)

RGD ID:

9060478

Description:

ENCODES a protein that exhibits ABC-type glutathione S-conjugate transporter activity (ortholog); ABC-type transporter activity (ortholog); ABC-type vitamin B12 transporter activity (ortholog); INVOLVED IN astrocyte differentiation (ortholog); carboxylic acid transmembrane transport (ortholog); cell chemotaxis (ortholog); PARTICIPATES IN docetaxel pharmacodynamics pathway; doxorubicin pharmacokinetics pathway; irinotecan pharmacodynamics pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN apical plasma membrane (ortholog); basal plasma membrane (ortholog); basolateral plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ATP binding cassette subfamily C member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; multidrug resistance-associated protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	729,316 - 860,290 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	729,322 - 858,826 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

asthma (ISO)

autistic disorder (ISO)

autosomal dominant nonsyndromic deafness 77 (ISO)

bacterial pneumonia (ISO)

Breast Cancer, Familial (ISO)

Breast Neoplasms (ISO)

Chemical and Drug Induced Liver Injury (ISO)

chronic obstructive pulmonary disease (ISO)

Colorectal Neoplasms (ISO)

Desbuquois Dysplasia 1 (ISO)

Disease Progression (ISO)

epilepsy (ISO)

head and neck squamous cell carcinoma (ISO)

heart disease (ISO)

hypertension (ISO)

intestinal volvulus (ISO)

lung cancer (ISO)

peripheral nervous system disease (ISO)

pseudoxanthoma elasticum (ISO)

schizophrenia (ISO)

Volvulus Of Midgut (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

astrocyte differentiation (ISO)

carboxylic acid transmembrane transport (ISO)

cell chemotaxis (ISO)

cellular response to amyloid-beta (ISO)

cobalamin transport (ISO)

cyclic nucleotide transport (ISO)

export across plasma membrane (ISO)

glial cell differentiation (ISO)

glutathione transmembrane transport (ISO)

leukotriene transport (ISO)

long-chain fatty acid import across plasma membrane (ISO)

phospholipid efflux (ISO)

phospholipid translocation (ISO)

positive regulation of cell migration (ISO)

positive regulation of inflammatory response (ISO)

regulation of cellular response to drug (ISO)

response to oxidative stress (ISO)

response to xenobiotic stimulus (ISO)

sphingolipid translocation (ISO)

transepithelial transport (ISO)

transmembrane transport (ISO)

xenobiotic detoxification by transmembrane export across the plasma membrane (ISO)

xenobiotic transport (ISO)

xenobiotic transport across blood-brain barrier (ISO)

Cellular Component

apical plasma membrane (ISO)

basal plasma membrane (ISO)

basolateral plasma membrane (ISO)

lateral plasma membrane (ISO)

plasma membrane (ISO)

Molecular Function

ABC-type glutathione S-conjugate transporter activity (ISO)

ABC-type transporter activity (ISO)

ABC-type vitamin B12 transporter activity (ISO)

ABC-type xenobiotic transporter activity (ISO)

amide transmembrane transporter activity (ISO)

ATPase-coupled lipid transmembrane transporter activity (ISO)

carboxylic acid transmembrane transporter activity (ISO)

efflux transmembrane transporter activity (ISO)

glutathione transmembrane transporter activity (ISO)

long-chain fatty acid transmembrane transporter activity (ISO)

xenobiotic transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

docetaxel pharmacodynamics pathway (ISO)

doxorubicin pharmacokinetics pathway (ISO)

irinotecan pharmacodynamics pathway (ISO)

irinotecan pharmacokinetics pathway (ISO)

lamivudine pharmacokinetics pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

sphingosine 1-phosphate signaling pathway (ISO)

tyrosinemia type III pathway (ISO)

vinblastine pharmacodynamics pathway (ISO)

vincristine pharmacodynamics pathway (ISO)

vindesine pharmacodynamics pathway (ISO)

vinorelbine pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Abcc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	729,316 - 860,290 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	729,322 - 858,826 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABCC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	15,949,143 - 16,143,053 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	15,949,138 - 16,143,257 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	16,043,473 - 16,236,910 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	15,950,935 - 16,144,432 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	15,950,934 - 16,143,774	NCBI
Celera	16	15,781,784 - 15,917,085 (+)	NCBI		Celera
Cytogenetic Map	16	p13.11	NCBI
HuRef	16	15,436,705 - 15,630,893 (+)	NCBI		HuRef
CHM1_1	16	16,185,916 - 16,321,192 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	15,954,068 - 16,147,908 (+)	NCBI		T2T-CHM13v2.0

Abcc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	14,179,317 - 14,292,743 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	14,179,422 - 14,293,601 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	14,361,453 - 14,474,878 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	14,361,558 - 14,475,737 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	14,361,653 - 14,474,968 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	14,275,138 - 14,388,453 (+)	NCBI		MGSCv36	mm8
Celera	16	14,966,079 - 15,077,783 (+)	NCBI		Celera
Cytogenetic Map	16	A1	NCBI
cM Map	16	9.75	NCBI

Abcc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	1,022,041 - 1,162,431 (-)	NCBI		GRCr8
mRatBN7.2	10	528,961 - 655,179 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	531,812 - 655,114 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	5,228,580 - 5,351,880 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	35,213,968 - 35,337,275 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	543,174 - 666,513 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	549,537 - 672,235 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	549,883 - 672,196 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	11,232,233 - 11,354,931 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	452,239 - 575,705 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	452,238 - 575,705 (-)	NCBI
Celera	10	11,130,945 - 11,246,232 (-)	NCBI		Celera
Cytogenetic Map	10	q11	NCBI

ABCC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	16,295,604 - 16,482,561 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	19,921,573 - 20,108,728 (+)	NCBI		NHGRI_mPanPan1

ABCC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	27,855,702 - 27,950,140 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	27,855,702 - 27,989,331 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	29,219,306 - 29,353,121 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	28,018,483 - 28,152,589 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	28,010,824 - 28,152,766 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	27,821,973 - 27,955,836 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	27,711,967 - 27,845,729 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	28,117,166 - 28,251,282 (-)	NCBI		UU_Cfam_GSD_1.0

Abcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	115,297,821 - 115,369,238 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	3,401,285 - 3,470,460 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	3,400,971 - 3,467,061 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	28,360,873 - 28,473,456 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	28,360,868 - 28,472,940 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	29,082,788 - 29,172,693 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	14,972,589 - 15,164,594 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	14,972,646 - 15,164,567 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	14,816,018 - 14,953,501 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Abcc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	449,288 - 591,310 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	449,217 - 590,306 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005391080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01037429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01153989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000019011 ⟹ ENSCLAP00000018826

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955442	729,316 - 860,290 (+)	Ensembl

RefSeq Acc Id:

XM_005391080 ⟹ XP_005391137

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955442	729,322 - 858,826 (+)	NCBI

Sequence:

show sequence

CGCTGGCCAACCCGGCGGCGTTGCGGCCCCGCTCGACTCCTCCGCCGCCGCCGTCAGCGCCGGC
CGTCTTCCCGCTGCCGAGCCCTCGCCGCCGCCTGCATGGCGCTCAGCGGCTTCTGCAGATCCGA
GGGCTCCGACCCCTTCTGGGACTGGAATGCCACATGGTACACCAGCAACCCTGACTTCACCAAG
TGCTTTCAGAACACCGTCCTCGTGTGGGTGCCTTGCTGCTACCTCTGGGCCTGCTTCCCTTTCT
ACTTCCTCTATCTCTCCCGACATGACCGGGGCTACATTCAGATGACGCACCTCAACAAAGCCAA
AACTGCCTTGGGATTCTTGCTGTGGATTGTCTGCTGGGCAGACCTCTTCTACTCTTTCTGGGAA
AGAAGTCAGGGCAAGCTCCTGCCCCCAGTGTTGCTGGTCAGCCCCACTCTCTTGGGTATCACCA
TGCTGCTCGCTACCTTTTTGATTCAGCTTGAGAGAAGGAAGGGTGTTCAGTCCTCGGGGGTCAT
GCTTATTTTCTGGCTTACAGCCCTGCTGTGTGCCCTGGCCATCTTCAGGTCCAGAATCATGTCT
GCCTTAAAAGAGGCCACCAAAGACAACCTGTTTCGCGATATCACTTTCTACTTGTACTTTTTCC
TTGTGCTGATTCAACTTGTGTTGGCCTGTTTCTCTGACCGCTTGCCTCTGTTCTCTGAAACCAT
CAACGACCCCAATCCTTGCCCGGAATCCGGCGCCTCATTCCTTTCCAAGATCACCTTCTGGTGG
ATCACAGGGTTGATGATCCGAGGCTACCGGCAGCCCTTGGAGGGCGGTGACCTCTGGTCTCTGA
ATAAGGAGGACACATCAGAACAAGTCGTGCCTGTGTTGGTGAAGAATTGGAAGAAGGAATGTGC
CAAGTCTAGGAGGCAGCCAGTGAAGATGGTGTACTCCGCCTCCAAGGATGCTGCCAAGCCCAAG
GGGAATTCCAAGGTGGATGTGAACGAGGAGGCTGAGGCCCTGATTGTCAAGTCCCCCCAGAAGG
AGCGGGACCCCTCCCTGTTTAAAGTGTTGTACAAGACCTTCGGGCCCTACTTCCTCATGAGCTT
CTTATTTAAGGCCCTTCATGACCTGATGATGTTTGCTGGGCCTGAGATCTTAAAGTTGCTCATT
CACTTTGTCAACGACAAGAAAGCCCCAGACTGGCAGGGCTACTTCTACACGGCGCTGCTGTTCG
TGAGCGCCTGCCTGCAGACGCTGGTGCTGCACCAGTACTTCCACATCTGCTTCGTCAGCGGCAT
GAGGATCAAGACCGCTGTCATCGGGGCTGTCTACCGCAAGGCCCTGGTGATCACCAATTCAGCT
AGAAAGTCCTCCACAGTTGGTGAGATTGTCAACCTCATGTCTGTGGATGCCCAGAGGTTCATGG
ACTTGGCCACGTACATTAACATGATCTGGTCGGCCCCCCTGCAAGTCATCCTCGCCCTCTACCT
CCTCTGGCTGAACCTGGGTCCCTCAGTCCTGGCTGGGGTGGCTGTGATGATCCTCATGGTGCCC
TTTAATGCTGTGATGGCAATGAAGACCAAGACCTATCAGGTGGCTCACATGAAGAGCAAAGACA
ATCGTATTAAGCTCATGAATGAAATTCTCAACGGGATCAAAGTGCTGAAGCTGTACGCATGGGA
GCTGGCGTTCAAGGACAAGGTGATGGCCATCAGGCAGGAGGAGCTGAAGGTGCTGAAGAAATCT
GCCTACCTGGCGGCCGTGGGGACCTTCACCTGGGTCTGCACACCTTTTCTGGTGGCCCTGTCTA
CATTTGCCGTCTATGTGACTGTCGACAAGAACAACGTCCTGGATGCCCAGAAAGCCTTCGTGTC
CTTGGCCTTGTTCAACATCCTCCGCTTTCCCCTGAACATCCTCCCCATGGTCATCAGCAGCATC
GTGCAGGCGAGTGTCTCTCTCAAACGCCTGAGGATCTTCCTTTCCCACGAGGAGCTGGAGCCTG
GTAGCATTGAGCGGCAGCCTGTCAAAGATGCTGCGGGGACAAACAGCATTACCGTGAGGAATGC
CACGTTCACATGGGCCAGAGGTGAAGCCCCTACACTGAATGGCATCACCTTCTCCATCCCGGAA
GGCGCCTTGGTGGCTGTGGTAGGCCAGGTGGGCTGTGGAAAGTCATCTTTGCTCTCGGCCCTCT
TGGCAGAGATGGACAAGCTGGAAGGTCACGTGGCTCTCAAGGGCTCGGTGGCCTACGTTCCCCA
ACAGGCCTGGATTCAGAATGACTCTCTCCGAGAAAACATCCTCTTTGGGCGCCAGCTGCAGGAA
CAGCACTACAAGGCTGTCATCAAGGCCTGTGCCCTCCTCCCAGACTTGGAAATCCTGCCCAGCG
GGGACCGGACCGAGATTGGTGAGAAGGGTGTGAACCTGTCCGGGGGCCAGAAGCAGCGTGTGAG
CCTGGCCCGGGCCGTGTACTGTGACTCAGACATCTACCTCTTCGATGACCCCCTCTCAGCTGTG
GATGCCCACGTGGGAAAGCACATTTTTGACAACGTGATTGGTCCCAAGGGGATGCTGAAGAATA
AGACTCGGATCCTGGTCACACATGGCATCAGCTACCTACCGCAGGTGGATGTCATTGTCGTCAT
GACTGGCGGCAAGATCTCCGAGATGGGCTCTTACCAGGAGCTGCTAGCCCGGGATGGGGCCTTT
GCCGAATTCTTGCGCACATATGCCAGCGCGGAGCAGGAACAGGCCTCAGAGGATGATGGGATGA
CAGGCATCAGCGGTCCAGGAAAGGAAGCAAAGCAAATGGAGAATGGCACGCTGGTGATGGACAC
CGCTGGGAAGCAGCTGCAGAGGCAGCTCAGCAACTCCTCCTCCTACAGTGGCGACGTCAGCAAG
CACCACACCAGCACCGCTGAGCTACAGAAACCCAGGGCCCAGGAGGAGAACTGGAAGCTGATGG
AGGCGGATAAGGCGCAGACAGGGCAGGTGCAGCTCTCGGTGTACTGGGACTACATGAAGGCCAT
CGGGCTCTTCCTCTCCTTTCTGAGCATCTTCCTCTTCCTGTGCAACCACATTTCCTCCCTGGCT
TCCAACTACTGGCTCAGTCTCTGGACGGACGACCCTGTCGTCAATGGGACCCAGGAGCACACGA
AAGTCCGGCTCAGCGTCTACGGAGCTCTGGGCATCTCACAAGGTGTCGCTGTGTTCGGCTACTC
TATGACAGTGTCCATTGGAGGCATCTTTGCCTCCCGCCGCCTGCACCTAGACCTGCTGTACAAT
GTCCTCCGGTCACCCATGAGCTTCTTCGAGCGCACCCCCAGCGGGAACCTGGTGAACCGCTTCT
CCAAGGAGCTGGACACGGTAGACTCCATGATCCCGCAAGTCATCAAGATGTTCATGGGCTCCCT
GTTCACTGTACTGGGCTCCTGCATCCTCATTCTGCTGGCCACCCCCATCGCTGCTGTCGTCATC
CCGCCACTGGGCCTCATCTACTTCTTCGTGCAGAGGTTCTACGTGGCTTCCTCTCGGCAGCTAA
AGCGCCTTGAGTCAGTCAGCCGCTCCCCAATTTACTCCCACTTCAACGAGACCTTGCTGGGGGT
CAGCGTCATCCGCGCCTTCGAGGAGCAGGAACGTTTTATCCACCAGAGTGACCTGAAGGTGGAC
GAGAATCAGAAGGCTTACTACCCCAGCATCGTGGCCAACAGGTGGCTCGCTGTGCGACTGGAGT
GTGTCGGAAACTGTATCGTCCTGTTTGCCGCACTCTTTGCGGTCATCTCCCGGCACAACCTCAG
TGCCGGCCTGGTGGGCCTCTCGGTGTCTTACTCCCTGCAGATCACCTCGTACTTGAACTGGCTG
GTTCGGATGTCTTCTGAGATGGAGACCAACATTGTAGCTGTGGAGAGACTCAAGGAGTATTCAG
AAACGGAGAAAGAGGCTCCCTGGCAAATCCAGGAGACAGCTCCACCCAGCAGCTGGCCCCAGGT
AGGCCGAGTGGAGTTCCGGGATTATGGCCTGCGGTACCGAGAGGACCTGGACTTGGTTCTCAAG
CACATCAACGTCATCATCGAAGGGGGAGAAAAGGTTGGCATTGTAGGGCGCACAGGAGCCGGCA
AGTCCTCCCTCACCCTGGGCTTGTTTCGGGTGAATGAGTCCGCTGAAGGCGAGATCATCATCGA
TGGTATCAATATCGCCAAGATCGGCCTGCACAACCTGCGCTTCAAAATCACCATCATCCCCCAG
GACCCCGTTTTGTTCTCGGGCTCTCTCCGCATGAACCTGGACCCGTTCAGCCAGTACTCAGATG
AAGAAGTCTGGACAGCCCTGGAGCTGGCTCACCTCAAGGGCTTCGTGTCCGGCCTCCCCGACAA
GCTGAACCATGAGTGTGCGGAAGGCGGGGAGAACCTAAGCATTGGGCAGCGCCAACTAGTGTGC
CTGGCCCGAGCTTTGCTGAGGAAGACAAAGATCCTTGTGCTGGATGAGGCCACGGCAGCCGTGG
ACCTGGAAACAGATGACCTCATCCAGTCCACCATTAGGACACAATTCGAGGACTGTACGGTCCT
CACCATTGCCCACCGACTCAACACCATCATGGACTACACAAGGGTGATTGTGCTGGACAAAGGG
GAGATCCGGGAGTGCGGCACCCCATCCGACCTCCTACAGCAGAGAGGTCTCTTCTATAGCATGG
CCAAAGATGCCGGCTTGGTGTGAGCGCAAGAGCTGGGGCACCTGGTCAGAACTGCAGGGCCGAC
ACACCAGTGTCCAGGGATGAGCCGGTGTCCTTGGGAACCCAGACCTCTCAGTCAGAAACCAAAA
AAAAAAAAAGGAAAGAAAGAAAACCAAACCCATCAAACCAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005391137	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000018826
	ENSCLAP00000018826.1

RefSeq Acc Id:

XP_005391137 ⟸ XM_005391080

- UniProtKB:

A0A8C2VTZ0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALSGFCRSEGSDPFWDWNATWYTSNPDFTKCFQNTVLVWVPCCYLWACFPFYFLYLSRHDRGY
IQMTHLNKAKTALGFLLWIVCWADLFYSFWERSQGKLLPPVLLVSPTLLGITMLLATFLIQLER
RKGVQSSGVMLIFWLTALLCALAIFRSRIMSALKEATKDNLFRDITFYLYFFLVLIQLVLACFS
DRLPLFSETINDPNPCPESGASFLSKITFWWITGLMIRGYRQPLEGGDLWSLNKEDTSEQVVPV
LVKNWKKECAKSRRQPVKMVYSASKDAAKPKGNSKVDVNEEAEALIVKSPQKERDPSLFKVLYK
TFGPYFLMSFLFKALHDLMMFAGPEILKLLIHFVNDKKAPDWQGYFYTALLFVSACLQTLVLHQ
YFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSA
PLQVILALYLLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNG
IKVLKLYAWELAFKDKVMAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNN
VLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPGSIERQPVKDAA
GTNSITVRNATFTWARGEAPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKLEGHVA
LKGSVAYVPQQAWIQNDSLRENILFGRQLQEQHYKAVIKACALLPDLEILPSGDRTEIGEKGVN
LSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFDNVIGPKGMLKNKTRILVTHGISY
LPQVDVIVVMTGGKISEMGSYQELLARDGAFAEFLRTYASAEQEQASEDDGMTGISGPGKEAKQ
MENGTLVMDTAGKQLQRQLSNSSSYSGDVSKHHTSTAELQKPRAQEENWKLMEADKAQTGQVQL
SVYWDYMKAIGLFLSFLSIFLFLCNHISSLASNYWLSLWTDDPVVNGTQEHTKVRLSVYGALGI
SQGVAVFGYSMTVSIGGIFASRRLHLDLLYNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIP
QVIKMFMGSLFTVLGSCILILLATPIAAVVIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPIY
SHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAAL
FAVISRHNLSAGLVGLSVSYSLQITSYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQE
TAPPSSWPQVGRVEFRDYGLRYREDLDLVLKHINVIIEGGEKVGIVGRTGAGKSSLTLGLFRVN
ESAEGEIIIDGINIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTALELAHL
KGFVSGLPDKLNHECAEGGENLSIGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTI
RTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGTPSDLLQQRGLFYSMAKDAGLV

hide sequence

Ensembl Acc Id:

ENSCLAP00000018826 ⟸ ENSCLAT00000019011

Protein Domains

ABC transmembrane type-1 ABC transporter

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000012896	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000019011	ENTREZGENE
	ENSCLAT00000019011.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1560.10	UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ABC1_TM_dom	UniProtKB/TrEMBL
	ABC1_TM_sf	UniProtKB/TrEMBL
	ABC_transporter-like_ATP-bd	UniProtKB/TrEMBL
	ABC_transporter-like_CS	UniProtKB/TrEMBL
	ABC_transporter_C	UniProtKB/TrEMBL
	Multidrug-R_assoc	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Abcc1	ENTREZGENE
PANTHER	ATP-BINDING CASSETTE SUB-FAMILY C	UniProtKB/TrEMBL
	MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1	UniProtKB/TrEMBL
Pfam	ABC_membrane	UniProtKB/TrEMBL
	ABC_tran	UniProtKB/TrEMBL
PROSITE	ABC_TM1F	UniProtKB/TrEMBL
	ABC_TRANSPORTER_1	UniProtKB/TrEMBL
	ABC_TRANSPORTER_2	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
	SSF90123	UniProtKB/TrEMBL
UniProt	A0A8C2VTZ0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-11-07	Abcc1	ATP binding cassette subfamily C member 1 (ABCC1 blood group)	Abcc1	ATP binding cassette subfamily C member 1	Symbol and/or name change	5135510	APPROVED
2016-08-16	Abcc1	ATP binding cassette subfamily C member 1		ATP-binding cassette, sub-family C (CFTR/MRP), member 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - PID (archival)