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Gene: Erp29 (endoplasmic reticulum protein 29) Chinchilla lanigera

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Symbol:

Erp29

Name:

endoplasmic reticulum protein 29

RGD ID:

9054170

Description:

ENCODES a protein that exhibits protein homodimerization activity (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN negative regulation of gene expression (ortholog); negative regulation of protein secretion (ortholog); positive regulation of gene expression (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH hepatocellular carcinoma (ortholog); lung adenocarcinoma (ortholog); Neoplasm Metastasis (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); smooth endoplasmic reticulum (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

endoplasmic reticulum resident protein 29

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	8,572,227 - 8,579,946 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955482	8,572,227 - 8,579,589 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hepatocellular carcinoma (ISO)

lung adenocarcinoma (ISO)

Neoplasm Metastasis (ISO)

Prostatic Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of gene expression (ISO)

negative regulation of protein secretion (ISO)

positive regulation of gene expression (ISO)

positive regulation of MAPK cascade (ISO)

regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (ISO)

Cellular Component

cell surface (ISO)

endoplasmic reticulum (ISO)

smooth endoplasmic reticulum (ISO)

Molecular Function

protein binding (ISO)

protein homodimerization activity (ISO)

protein-folding chaperone binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

codeine and morphine pharmacodynamics pathway (ISO)

codeine and morphine pharmacokinetics pathway (ISO)

etoposide pharmacodynamics pathway (ISO)

etoposide pharmacokinetics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacokinetics pathway (ISO)

irinotecan pharmacodynamics pathway (ISO)

irinotecan pharmacokinetics pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

retinol metabolic pathway (ISO)

sorafenib pharmacokinetics pathway (ISO)

vitamin A deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Erp29
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955482	8,572,227 - 8,579,946 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955482	8,572,227 - 8,579,589 (+)	NCBI	ChiLan1.0	ChiLan1.0

ERP29
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	112,013,426 - 112,023,449 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	112,013,348 - 112,023,449 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	112,451,230 - 112,461,253 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	110,935,535 - 110,945,407 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	110,913,981 - 110,923,343	NCBI
Celera	12	112,076,622 - 112,086,494 (+)	NCBI		Celera
Cytogenetic Map	12	q24.13	NCBI
HuRef	12	109,464,438 - 109,474,310 (+)	NCBI		HuRef
CHM1_1	12	112,419,401 - 112,429,273 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	111,990,331 - 112,000,354 (+)	NCBI		T2T-CHM13v2.0

Erp29
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	121,582,816 - 121,590,537 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	121,566,653 - 121,590,569 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	121,444,753 - 121,452,474 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	121,428,590 - 121,452,506 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	121,894,762 - 121,902,483 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	121,705,370 - 121,713,091 (-)	NCBI		MGSCv36	mm8
Celera	5	118,534,620 - 118,542,346 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	61.8	NCBI

Erp29
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	40,750,177 - 40,756,607 (+)	NCBI		GRCr8
mRatBN7.2	12	35,089,698 - 35,095,952 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	35,089,707 - 35,096,376 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	36,262,678 - 36,268,916 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	36,873,883 - 36,880,123 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	35,926,324 - 35,932,562 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	40,619,377 - 40,625,884 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	40,619,377 - 40,625,883 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	42,486,492 - 42,492,999 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	36,225,110 - 36,231,363 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	36,085,146 - 36,094,834 (+)	NCBI
Celera	12	36,754,491 - 36,760,744 (+)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

ERP29
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	120,104,319 - 120,114,293 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	120,098,070 - 120,110,685 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	109,610,692 - 109,620,390 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	113,004,125 - 113,013,674 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	113,004,125 - 113,013,674 (+)	Ensembl	panpan1.1		panPan2

ERP29
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	9,608,352 - 9,616,711 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	9,608,399 - 9,616,338 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	9,727,228 - 9,735,252 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	9,846,360 - 9,854,389 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	9,846,421 - 9,855,488 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	9,823,443 - 9,831,474 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	9,886,854 - 9,894,877 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	9,933,751 - 9,942,250 (+)	NCBI		UU_Cfam_GSD_1.0

Erp29
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	154,940,483 - 154,948,059 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936558	4,531,471 - 4,538,943 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936558	4,531,397 - 4,538,943 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ERP29
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	39,687,000 - 39,695,752 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	39,687,028 - 39,695,748 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	42,178,792 - 42,187,512 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ERP29
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	107,244,359 - 107,255,293 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	107,244,335 - 107,256,499 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	137,833,226 - 137,844,448 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Erp29
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	20,166,371 - 20,175,012 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	20,167,197 - 20,174,914 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005403185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005403186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01057536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01057537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01045015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000020024 ⟹ ENSCLAP00000019831

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955482	8,572,227 - 8,579,946 (+)	Ensembl

RefSeq Acc Id:

XM_005403185 ⟹ XP_005403242

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955482	8,572,227 - 8,579,589 (+)	NCBI

Sequence:

show sequence

GCGCGCGGCACCGCCCTCCTAGTCACGTGATCGCTGATTGGGAACGTTTTCCCTACTGCTCTCC
TACCTCCGGCTCCCAGAATCCTGCGCTATGGCTGCCGCTGTACCGCGTGTCGCTTCTCTCTCCT
CTCTGTTTCCCCTTTTTCTGAGTCTCCTGCTTTTCTCCGCCCCTCATGGCGGCAGCGGCCTGCA
CACTAAGGGCGCCCTTCCCCTGGATACAGTCACTTTCTATAAGGTCATTCCCAAAAGCAAGTTC
GTCTTGGTGAAGTTCGACACCCAATACCCCTACGGTGAGAAGCAGGACGAGTTCAAGCGACTGG
CTGAAAACTCGGCCTCCAGTGATGATCTCTTGGTGGCAGAGGTGGGGATTTCAGATTATGGTGA
CAAACTGAACATGGAGCTGAGTGAGAAATATAAGCTGGATAAAGAGAACTACCCAGTCTTTTAC
CTCTTCCGGGACGGAGACTTTGAGAACCCAGTCCCATACAGTGGGGCAGTTAAGGTTGGAGCCA
TCCAGCGCTGGCTGAAGGGGCAAGGGGTCTACCTGGGTATGCCAGGTTGCCTGCCTGCCTATGA
TGCCCTGGCGGGGGACTTCCTCAGGGCCTCTAGTGTGGAGGCCCGCCGGGCGCTCTTGAAGCAG
GGGCAGGACAACCTCTCAAGTGTGAAAGAGACTGAAAAGAAGTGGGCTGAACAATACCTGAAGA
TCATGGGGAAGGTCTTAGATCAAGGTGAGGACTTCCCAGCAACAGAGGTGTCTCGAATCACCAA
GCTGATTGAGAAGAATAAGATGAGCGATGGGAAGAAGGAAGAGCTCCAGAAGAGCTTAAACATC
CTAACTGCCTTCCAGAAAAAGGGGGTAGAGAAGGAGGAACTGTGAGAAGGCACTCTGGAGTGTC
CCAGGGTTTGCTGGGGTAGGGAAGGGAGGGGAGAATTACCTGCTGGCTGCAAGACTTTTGTGGG
GTATCAGGGGGTAGTGGAAAAACTGCTATTAAACCAGAAATCTGAGCCCTGAATATGCCTGGAC
ATCGATGCTGATGTGACCATGCTTAGGACACCTCTAGAGCCAGTGTGGGGACAGCTGGAGCATT
TACTCTGATGAGAGAAGGAATCGGTGCTACAAAGAGGCAGGTACTGCCCAGGTCCTTGACAAGT
GTAATTCTGATCCAAATAAAGTTTCAGTGTTTTGGCTAA

hide sequence

RefSeq Acc Id:

XM_005403186 ⟹ XP_005403243

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955482	8,572,227 - 8,578,891 (+)	NCBI

Sequence:

show sequence

GCGCGCGGCACCGCCCTCCTAGTCACGTGATCGCTGATTGGGAACGTTTTCCCTACTGCTCTCC
TACCTCCGGCTCCCAGAATCCTGCGCTATGGCTGCCGCTGTACCGCGTGTCGCTTCTCTCTCCT
CTCTGTTTCCCCTTTTTCTGAGTCTCCTGCTTTTCTCCGCCCCTCATGGCGGCAGCGGCCTGCA
CACTAAGGGCGCCCTTCCCCTGGATACAGTCACTTTCTATAAGATTATGGTGACAAACTGAACA
TGGAGCTGAGTGAGAAATATAAGCTGGATAAAGAGAACTACCCAGTCTTTTACCTCTTCCGGGA
CGGAGACTTTGAGAACCCAGTCCCATACAGTGGG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005403242	(Get FASTA)	NCBI Sequence Viewer
	XP_005403243	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000019831
	ENSCLAP00000019831.1

RefSeq Acc Id:	XP_005403243 ⟸ XM_005403186
- Peptide Label:	isoform X2
- Sequence:	show sequence MAAAVPRVASLSSLFPLFLSLLLFSAPHGGSGLHTKGALPLDTVTFYKIMVTN hide sequence

RefSeq Acc Id:	XP_005403242 ⟸ XM_005403185
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VSD6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAAVPRVASLSSLFPLFLSLLLFSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQY PYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKENYPVFYLFRDGDFEN PVPYSGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGDFLRASSVEARRALLKQGQDNLSSVK ETEKKWAEQYLKIMGKVLDQGEDFPATEVSRITKLIEKNKMSDGKKEELQKSLNILTAFQKKGV EKEEL hide sequence

Ensembl Acc Id:

ENSCLAP00000019831 ⟸ ENSCLAT00000020024

Protein Domains

Endoplasmic reticulum resident protein 29 C- ERp29 N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013597	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000020024	ENTREZGENE
	ENSCLAT00000020024.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1150.12	UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/TrEMBL
InterPro	ERp29	UniProtKB/TrEMBL
	ERp29_C	UniProtKB/TrEMBL
	ERp29_C_sf	UniProtKB/TrEMBL
	ERp29_N	UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/TrEMBL
NCBI Gene	Erp29	ENTREZGENE
PANTHER	ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29	UniProtKB/TrEMBL
	PTHR12211	UniProtKB/TrEMBL
Pfam	ERp29	UniProtKB/TrEMBL
	ERp29_N	UniProtKB/TrEMBL
PIRSF	ER_p29	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47933	UniProtKB/TrEMBL
	SSF52833	UniProtKB/TrEMBL
UniProt	A0A8C2VSD6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - CTD

Imported Annotations - SMPDB