Cct8 (chaperonin containing TCP1 subunit 8) - Rat Genome Database

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Gene: Cct8 (chaperonin containing TCP1 subunit 8) Chinchilla lanigera
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Symbol: Cct8
Name: chaperonin containing TCP1 subunit 8
RGD ID: 9048215
Description: ENCODES a protein that exhibits protein folding chaperone (ortholog); INVOLVED IN binding of sperm to zona pellucida (ortholog); chaperone-mediated protein folding (ortholog); positive regulation of protein localization to Cajal body (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell body (ortholog); centrosome (ortholog); chaperonin-containing T-complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chaperonin containing TCP1, subunit 8 (theta); T-complex protein 1 subunit theta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,414,583 - 28,428,215 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540728,414,583 - 28,427,964 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cct8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,414,583 - 28,428,215 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540728,414,583 - 28,427,964 (-)NCBIChiLan1.0ChiLan1.0
CCT8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382129,056,326 - 29,073,648 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2129,055,805 - 29,073,797 (-)EnsemblGRCh38hg38GRCh38
GRCh372130,428,647 - 30,445,969 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,350,518 - 29,367,881 (-)NCBINCBI36Build 36hg18NCBI36
Build 342129,350,517 - 29,367,881NCBI
Celera2115,612,113 - 15,629,468 (-)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2115,834,853 - 15,852,223 (-)NCBIHuRef
CHM1_12129,990,996 - 30,008,352 (-)NCBICHM1_1
T2T-CHM13v2.02127,419,768 - 27,437,088 (-)NCBIT2T-CHM13v2.0
Cct8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391687,280,213 - 87,292,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1687,280,214 - 87,292,761 (-)EnsemblGRCm39 Ensembl
GRCm381687,483,325 - 87,495,869 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1687,483,326 - 87,495,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv371687,483,570 - 87,496,114 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361687,372,523 - 87,385,053 (-)NCBIMGSCv36mm8
Celera1687,677,894 - 87,690,438 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1649.57NCBI
Cct8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,196,619 - 40,208,328 (-)NCBIGRCr8
mRatBN7.21126,710,370 - 26,722,079 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,710,370 - 26,722,079 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,408,323 - 35,420,052 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,108,576 - 28,120,305 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,297,511 - 27,309,240 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,130,172 - 27,141,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,130,172 - 27,141,881 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01130,755,620 - 30,767,329 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,233,711 - 27,245,369 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11127,233,709 - 27,245,381 (-)NCBI
Celera1126,462,714 - 26,474,420 (-)NCBICelera
Cytogenetic Map11q11NCBI
CCT8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22225,240,125 - 25,258,138 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12120,098,602 - 20,116,554 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02115,489,698 - 15,507,292 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12128,878,113 - 28,895,912 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2128,878,113 - 28,895,912 (-)Ensemblpanpan1.1panPan2
CCT8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13124,061,185 - 24,075,002 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3124,061,252 - 24,075,364 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3124,054,512 - 24,068,293 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03124,174,970 - 24,188,795 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3124,174,967 - 24,189,157 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13124,125,427 - 24,139,220 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03124,127,229 - 24,141,032 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03124,598,553 - 24,612,366 (-)NCBIUU_Cfam_GSD_1.0
Cct8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497124,505,117 - 24,518,165 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650012,949,563 - 12,965,064 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650012,949,563 - 12,962,699 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCT8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13192,407,735 - 192,423,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113192,407,831 - 192,423,466 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213202,710,318 - 202,726,009 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCT8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1263,151,783 - 63,169,249 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl263,151,481 - 63,169,098 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660715,736,497 - 5,754,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cct8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474517,030,539 - 17,043,637 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000006339   ⟹   ENSCLAP00000006236
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540728,414,583 - 28,428,215 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000006340   ⟹   ENSCLAP00000006237
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540728,414,724 - 28,427,893 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000006341   ⟹   ENSCLAP00000006238
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540728,415,091 - 28,428,215 (-)Ensembl
RefSeq Acc Id: XM_005375612   ⟹   XP_005375669
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540728,414,583 - 28,427,964 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005375613   ⟹   XP_005375670
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540728,414,583 - 28,427,962 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005375669 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375670 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000006236
  ENSCLAP00000006236.1
  ENSCLAP00000006237.1
  ENSCLAP00000006238
  ENSCLAP00000006238.1
RefSeq Acc Id: XP_005375670   ⟸   XM_005375613
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UV44 (UniProtKB/TrEMBL),   A0A8C2UW31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005375669   ⟸   XM_005375612
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YKX4 (UniProtKB/TrEMBL),   A0A8C2UW31 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000006236   ⟸   ENSCLAT00000006339
Ensembl Acc Id: ENSCLAP00000006238   ⟸   ENSCLAT00000006341
Ensembl Acc Id: ENSCLAP00000006237   ⟸   ENSCLAT00000006340


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004410 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000006339 ENTREZGENE
  ENSCLAT00000006339.1 UniProtKB/TrEMBL
  ENSCLAT00000006340.1 UniProtKB/TrEMBL
  ENSCLAT00000006341 ENTREZGENE
  ENSCLAT00000006341.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.560.10 UniProtKB/TrEMBL
  3.30.260.10 UniProtKB/TrEMBL
  3.50.7.10 UniProtKB/TrEMBL
InterPro Chap_CCT_theta UniProtKB/TrEMBL
  Chaperone_TCP-1 UniProtKB/TrEMBL
  Chaperonin_TCP-1_CS UniProtKB/TrEMBL
  Cpn60/GroEL/TCP-1 UniProtKB/TrEMBL
  GroEL-like_apical_dom_sf UniProtKB/TrEMBL
  GROEL-like_equatorial_sf UniProtKB/TrEMBL
  TCP-1-like_intermed_sf UniProtKB/TrEMBL
NCBI Gene Cct8 ENTREZGENE
PANTHER PTHR11353 UniProtKB/TrEMBL
Pfam Cpn60_TCP1 UniProtKB/TrEMBL
PRINTS TCOMPLEXTCP1 UniProtKB/TrEMBL
PROSITE TCP1_1 UniProtKB/TrEMBL
  TCP1_2 UniProtKB/TrEMBL
  TCP1_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48592 UniProtKB/TrEMBL
  SSF52029 UniProtKB/TrEMBL
  SSF54849 UniProtKB/TrEMBL
UniProt A0A8C2UV44 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UW31 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YKX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cct8  chaperonin containing TCP1 subunit 8    chaperonin containing TCP1, subunit 8 (theta)  Symbol and/or name change 5135510 APPROVED