Map3k13 (mitogen-activated protein kinase kinase kinase 13) - Rat Genome Database

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Gene: Map3k13 (mitogen-activated protein kinase kinase kinase 13) Chinchilla lanigera
Analyze
Symbol: Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
RGD ID: 9041746
Description: ENCODES a protein that exhibits enzyme binding (ortholog); identical protein binding (ortholog); IkappaB kinase complex binding (ortholog); INVOLVED IN JNK cascade (ortholog); peptidyl-serine phosphorylation (ortholog); positive regulation of axon extension (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH Currarino syndrome (ortholog); gastroesophageal adenocarcinoma (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542022,064,384 - 22,224,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542022,064,384 - 22,190,662 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Map3k13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542022,064,384 - 22,224,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542022,064,384 - 22,190,662 (-)NCBIChiLan1.0ChiLan1.0
MAP3K13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,282,961 - 185,489,094 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3185,282,941 - 185,489,094 (+)EnsemblGRCh38hg38GRCh38
GRCh373185,000,749 - 185,206,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,563,664 - 186,683,322 (+)NCBINCBI36Build 36hg18NCBI36
Build 343186,563,671 - 186,683,329NCBI
Celera3183,526,871 - 183,646,121 (+)NCBICelera
Cytogenetic Map3q27.2NCBI
HuRef3182,410,418 - 182,616,479 (+)NCBIHuRef
CHM1_13184,963,400 - 185,169,890 (+)NCBICHM1_1
T2T-CHM13v2.03188,098,494 - 188,304,852 (+)NCBIT2T-CHM13v2.0
Map3k13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391621,643,923 - 21,752,189 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1621,613,096 - 21,752,189 (+)EnsemblGRCm39 Ensembl
GRCm381621,824,056 - 21,933,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1621,794,346 - 21,933,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371621,892,042 - 21,931,950 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361621,805,952 - 21,846,450 (+)NCBIMGSCv36mm8
Celera1622,459,094 - 22,498,899 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1612.92NCBI
Map3k13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,596,436 - 92,741,717 (-)NCBIGRCr8
mRatBN7.21179,094,087 - 79,235,181 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1179,097,247 - 79,235,181 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1187,832,392 - 87,971,900 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,486,036 - 80,625,546 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01179,546,735 - 79,686,246 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01182,744,391 - 82,938,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,745,735 - 82,938,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,830,850 - 85,865,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,327,515 - 81,467,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1177,956,031 - 78,091,697 (-)NCBICelera
Cytogenetic Map11q23NCBI
MAP3K13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22183,158,285 - 183,361,330 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13183,163,002 - 183,366,047 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03182,319,405 - 182,517,655 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13190,875,284 - 190,993,633 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3190,798,694 - 190,993,633 (+)Ensemblpanpan1.1panPan2
MAP3K13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13418,081,158 - 18,252,800 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3418,083,595 - 18,247,367 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3422,196,773 - 22,338,512 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03418,019,990 - 18,159,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,990,427 - 18,159,873 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13418,055,958 - 18,195,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03418,051,916 - 18,191,465 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03418,281,506 - 18,423,763 (+)NCBIUU_Cfam_GSD_1.0
Map3k13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602118,272,160 - 118,441,123 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365784,368,900 - 4,532,966 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365784,363,361 - 4,461,133 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP3K13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113123,176,077 - 123,357,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213132,865,708 - 132,904,013 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAP3K13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1153,947,464 - 4,135,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl153,947,851 - 4,138,194 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606312,707,320 - 12,900,766 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map3k13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473071,161,646 - 71,312,442 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473071,162,598 - 71,313,369 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000021004   ⟹   ENSCLAP00000020804
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542022,064,384 - 22,104,229 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000021005   ⟹   ENSCLAP00000020805
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542022,067,442 - 22,224,789 (-)Ensembl
RefSeq Acc Id: XM_005383296   ⟹   XP_005383353
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542022,064,384 - 22,190,662 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383297   ⟹   XP_005383354
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542022,064,384 - 22,155,521 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513562   ⟹   XP_013369016
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542022,064,384 - 22,189,008 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005383353 (Get FASTA)   NCBI Sequence Viewer  
  XP_005383354 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369016 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000020804
  ENSCLAP00000020804.1
  ENSCLAP00000020805.1
RefSeq Acc Id: XP_005383353   ⟸   XM_005383296
- UniProtKB: A0A8C2W217 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005383354   ⟸   XM_005383297
- UniProtKB: A0A8C2W217 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369016   ⟸   XM_013513562
- UniProtKB: A0A8C2W217 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000020805   ⟸   ENSCLAT00000021005
Ensembl Acc Id: ENSCLAP00000020804   ⟸   ENSCLAT00000021004
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014253 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021004 ENTREZGENE
  ENSCLAT00000021004.1 UniProtKB/TrEMBL
  ENSCLAT00000021005.1 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  MAP3K12_MAP3K13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  Ser/Thr_Kinases-Pseudokinases UniProtKB/TrEMBL
NCBI Gene Map3k13 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 13 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
PIRSF MAPKKK12_MAPKKK13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2W217 ENTREZGENE, UniProtKB/TrEMBL