Hyou1 (hypoxia up-regulated 1) - Rat Genome Database

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Gene: Hyou1 (hypoxia up-regulated 1) Chinchilla lanigera
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Symbol: Hyou1
Name: hypoxia up-regulated 1
RGD ID: 9029045
Description: ENCODES a protein that exhibits ATP binding (ortholog); protein-folding chaperone binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); endoplasmic reticulum to Golgi vesicle-mediated transport (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum chaperone complex (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypoxia up-regulated protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,148,953 - 20,161,172 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,149,104 - 20,161,378 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hyou1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,148,953 - 20,161,172 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,149,104 - 20,161,378 (-)NCBIChiLan1.0ChiLan1.0
HYOU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,044,188 - 119,057,205 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,044,188 - 119,057,227 (-)EnsemblGRCh38hg38GRCh38
GRCh3711118,914,899 - 118,927,916 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,420,110 - 118,433,122 (-)NCBINCBI36Build 36hg18NCBI36
Celera11116,072,540 - 116,085,596 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,854,557 - 114,867,575 (-)NCBIHuRef
CHM1_111118,801,167 - 118,814,197 (-)NCBICHM1_1
T2T-CHM13v2.011119,064,550 - 119,077,556 (-)NCBIT2T-CHM13v2.0
Hyou1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,290,840 - 44,303,662 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,290,787 - 44,303,666 (+)EnsemblGRCm39 Ensembl
GRCm38944,379,490 - 44,392,369 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,379,490 - 44,392,369 (+)EnsemblGRCm38mm10GRCm38
MGSCv37944,187,573 - 44,200,452 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,130,580 - 44,143,364 (+)NCBIMGSCv36mm8
Celera941,627,066 - 41,639,919 (+)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Hyou1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,602,882 - 53,614,998 (+)NCBIGRCr8
mRatBN7.2844,706,073 - 44,718,189 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,706,263 - 44,718,186 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,202,146 - 50,214,290 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,480,862 - 48,493,006 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,351,091 - 46,363,246 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,699,796 - 48,711,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,699,769 - 48,711,910 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,318,767 - 47,330,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,346,753 - 47,358,869 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,355,708 - 47,366,413 (+)NCBI
Celera844,292,303 - 44,304,419 (+)NCBICelera
Cytogenetic Map8q22NCBI
HYOU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,749,015 - 119,762,064 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,852,712 - 120,865,769 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,882,418 - 113,895,438 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,812,050 - 117,825,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,812,975 - 117,824,005 (-)Ensemblpanpan1.1panPan2
HYOU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,795,750 - 14,808,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,795,750 - 14,807,262 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,848,571 - 14,860,968 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,738,891 - 14,751,288 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,738,464 - 14,751,437 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,876,904 - 14,889,447 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,780,910 - 14,793,451 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,821,311 - 14,832,539 (+)NCBIUU_Cfam_GSD_1.0
Hyou1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,084,483 - 101,101,869 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,005,610 - 4,018,135 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,005,616 - 4,018,135 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HYOU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,264,933 - 46,276,995 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,264,929 - 46,277,056 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,300,063 - 51,312,075 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HYOU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,418,497 - 110,431,636 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,417,942 - 110,431,590 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,603,358 - 15,616,849 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hyou1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,427,130 - 14,439,038 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,427,297 - 14,439,027 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000021956   ⟹   ENSCLAP00000021753
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541220,148,953 - 20,161,172 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000021957   ⟹   ENSCLAP00000021754
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541220,156,596 - 20,160,383 (-)Ensembl
RefSeq Acc Id: XM_005378294   ⟹   XP_005378351
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541220,149,104 - 20,161,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005378295   ⟹   XP_005378352
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541220,149,104 - 20,161,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005378296   ⟹   XP_005378353
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541220,149,104 - 20,161,172 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005378297   ⟹   XP_005378354
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541220,149,104 - 20,161,172 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005378351 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378352 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378353 (Get FASTA)   NCBI Sequence Viewer  
  XP_005378354 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021753
  ENSCLAP00000021753.1
  ENSCLAP00000021754.1
RefSeq Acc Id: XP_005378352   ⟸   XM_005378295
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VYY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005378351   ⟸   XM_005378294
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005378353   ⟸   XM_005378296
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VYY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005378354   ⟸   XM_005378297
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VYY1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000021753   ⟸   ENSCLAT00000021956
Ensembl Acc Id: ENSCLAP00000021754   ⟸   ENSCLAT00000021957


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014893 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021956 ENTREZGENE
  ENSCLAT00000021956.1 UniProtKB/TrEMBL
  ENSCLAT00000021957.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.10 UniProtKB/TrEMBL
  3.30.30.30 UniProtKB/TrEMBL
  3.30.420.40 UniProtKB/TrEMBL
  Actin, Chain A, domain 4 UniProtKB/TrEMBL
  Substrate Binding Domain Of DNAk, Chain A, domain 1 UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/TrEMBL
  Heat_shock_70_CS UniProtKB/TrEMBL
  HSP70_C_sf UniProtKB/TrEMBL
  HSP70_peptide-bd_sf UniProtKB/TrEMBL
  Hsp_70_fam UniProtKB/TrEMBL
NCBI Gene Hyou1 ENTREZGENE
PANTHER HSC70CB, ISOFORM G-RELATED UniProtKB/TrEMBL
  HYPOXIA UP-REGULATED PROTEIN 1 UniProtKB/TrEMBL
Pfam HSP70 UniProtKB/TrEMBL
PRINTS HEATSHOCK70 UniProtKB/TrEMBL
PROSITE HSP70_2 UniProtKB/TrEMBL
  HSP70_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF100934 UniProtKB/TrEMBL
  SSF53067 UniProtKB/TrEMBL
UniProt A0A8C2VYY1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W194_CHILA UniProtKB/TrEMBL