Abhd2 (abhydrolase domain containing 2, acylglycerol lipase) - Rat Genome Database

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Gene: Abhd2 (abhydrolase domain containing 2, acylglycerol lipase) Chinchilla lanigera
Analyze
Symbol: Abhd2
Name: abhydrolase domain containing 2, acylglycerol lipase
RGD ID: 9007630
Description: ENCODES a protein that exhibits acetylesterase activity (ortholog); diacylglycerol lipase activity (ortholog); hormone binding (ortholog); INVOLVED IN acrosome reaction (ortholog); acylglycerol catabolic process (ortholog); negative regulation of smooth muscle cell migration (ortholog); ASSOCIATED WITH amenorrhea (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN acrosomal vesicle (ortholog); sperm flagellum (ortholog); sperm plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: abhydrolase domain containing 2; abhydrolase domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,884,624 - 15,983,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,878,972 - 15,983,322 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Abhd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541615,884,624 - 15,983,322 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541615,878,972 - 15,983,322 (-)NCBIChiLan1.0ChiLan1.0
ABHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,040,998 - 89,202,355 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,087,459 - 89,202,355 (+)EnsemblGRCh38hg38GRCh38
GRCh371589,584,229 - 89,745,586 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361587,432,429 - 87,546,591 (+)NCBINCBI36Build 36hg18NCBI36
Build 341587,432,627 - 87,541,199NCBI
Celera1566,032,695 - 66,146,881 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1565,743,212 - 65,857,546 (+)NCBIHuRef
CHM1_11589,472,357 - 89,586,578 (+)NCBICHM1_1
T2T-CHM13v2.01586,795,895 - 86,957,178 (+)NCBIT2T-CHM13v2.0
Abhd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39778,923,002 - 79,015,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl778,922,947 - 79,015,256 (+)EnsemblGRCm39 Ensembl
GRCm38779,273,266 - 79,361,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,273,199 - 79,365,508 (+)EnsemblGRCm38mm10GRCm38
MGSCv37786,418,152 - 86,506,487 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,146,779 - 79,235,114 (+)NCBIMGSCv36mm8
Celera776,673,721 - 76,758,716 (+)NCBICelera
Cytogenetic Map7D2NCBI
cM Map744.96NCBI
Abhd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81142,626,748 - 142,707,892 (+)NCBIGRCr8
mRatBN7.21133,217,403 - 133,298,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,217,375 - 133,299,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,126,872 - 141,207,609 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,296,304 - 148,377,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,213,989 - 141,294,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01140,998,240 - 141,087,405 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1140,998,240 - 141,087,405 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,965,576 - 142,049,687 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,025,144 - 135,111,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11135,103,531 - 135,191,046 (+)NCBI
Celera1125,281,300 - 125,361,782 (+)NCBICelera
Cytogenetic Map1q31NCBI
ABHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21678,635,699 - 78,750,091 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11582,338,167 - 82,454,579 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01567,780,453 - 67,891,454 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11586,987,070 - 87,095,823 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1586,987,070 - 87,095,818 (+)Ensemblpanpan1.1panPan2
ABHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,151,500 - 52,255,024 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,151,535 - 52,249,612 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha354,787,785 - 54,891,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0352,570,316 - 52,673,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl352,570,371 - 52,673,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,092,905 - 52,196,309 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,303,690 - 52,406,947 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0352,642,383 - 52,745,916 (+)NCBIUU_Cfam_GSD_1.0
Abhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640131,254,659 - 131,360,435 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648314,974,035 - 15,074,154 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648314,974,053 - 15,079,824 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl754,655,804 - 54,770,131 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1754,655,694 - 54,776,140 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2759,630,969 - 59,746,589 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1297,631,436 - 7,742,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl297,631,412 - 7,740,394 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605939,085,426 - 39,196,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476816,297,464 - 16,402,624 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476816,283,369 - 16,404,476 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000021318   ⟹   ENSCLAP00000021117
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541615,884,624 - 15,983,322 (-)Ensembl
RefSeq Acc Id: XM_005381560   ⟹   XP_005381617
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541615,878,972 - 15,983,322 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381617 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021117
  ENSCLAP00000021117.1
RefSeq Acc Id: XP_005381617   ⟸   XM_005381560
- UniProtKB: A0A8C2VXD4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000021117   ⟸   ENSCLAT00000021318
Protein Domains
AB hydrolase-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014471 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021318 ENTREZGENE
  ENSCLAT00000021318.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  AB_hydrolase_4_CS UniProtKB/TrEMBL
  AB_hydrolase_4_sf UniProtKB/TrEMBL
  ABHD4 UniProtKB/TrEMBL
NCBI Gene Abhd2 ENTREZGENE
PANTHER ABHYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MONOACYLGLYCEROL LIPASE ABHD2 UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PIRSF Ab_hydro_YheT UniProtKB/TrEMBL
PROSITE UPF0017 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A8C2VXD4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 Abhd2  abhydrolase domain containing 2, acylglycerol lipase  Abhd2  abhydrolase domain containing 2  Symbol and/or name change 5135510 APPROVED