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Gene: Trpm4 (transient receptor potential cation channel subfamily M member 4) Chinchilla lanigera

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Symbol:

Trpm4

Name:

transient receptor potential cation channel subfamily M member 4

RGD ID:

8991887

Description:

ENCODES a protein that exhibits ATP binding (ortholog); calcium channel activity (ortholog); calcium ion binding (ortholog); INVOLVED IN calcium ion transport (ortholog); calcium-mediated signaling (ortholog); cellular response to ATP (ortholog); ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); atrioventricular block (ortholog); Bradycardia (ortholog); FOUND IN endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transient receptor potential cation channel, subfamily M, member 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,546,365 - 1,581,712 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,539,036 - 1,581,800 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

arrhythmogenic right ventricular cardiomyopathy (ISO)

atrioventricular block (ISO)

Bradycardia (ISO)

Brugada syndrome (ISO)

cardiac arrest (ISO)

Cardiac Conduction Defect (ISO)

Cardiomegaly (ISO)

cardiomyopathy (ISO)

catecholaminergic polymorphic ventricular tachycardia (ISO)

catecholaminergic polymorphic ventricular tachycardia 1 (ISO)

congestive heart failure (ISO)

developmental and epileptic encephalopathy 12 (ISO)

dilated cardiomyopathy (ISO)

epilepsy (ISO)

erythrokeratodermia variabilis et progressiva 6 (ISO)

Failure to Thrive (ISO)

genetic disease (ISO)

Heart Block (ISO)

heart conduction disease (ISO)

hypertrophic cardiomyopathy (ISO)

long QT syndrome (ISO)

myoepithelioma (ISO)

patent foramen ovale (ISO)

progressive familial heart block (ISO)

Progressive Familial Heart Block Type I (ISO)

progressive familial heart block type IA (ISO)

progressive familial heart block type IB (ISO)

Prostatic Neoplasms (ISO)

Respiration Disorders (ISO)

restrictive cardiomyopathy (ISO)

short QT syndrome (ISO)

Spinal Cord Injuries (ISO)

Subarachnoid Hemorrhage (ISO)

Sudden Cardiac Death (ISO)

Sudden Death (ISO)

Sudden Unexpected Nocturnal Death Syndrome (ISO)

Tachycardia (ISO)

Ventricular Fibrillation (ISO)

Ventricular Tachycardia (ISO)

West syndrome (ISO)

Wolff-Parkinson-White syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium ion transport (ISO)

calcium-mediated signaling (ISO)

cellular response to ATP (ISO)

dendritic cell chemotaxis (ISO)

inorganic cation transmembrane transport (ISO)

long-term memory (ISO)

membrane depolarization during AV node cell action potential (ISO)

membrane depolarization during bundle of His cell action potential (ISO)

membrane depolarization during Purkinje myocyte cell action potential (ISO)

negative regulation of bone mineralization (ISO)

negative regulation of osteoblast differentiation (ISO)

positive regulation of adipose tissue development (ISO)

positive regulation of atrial cardiac muscle cell action potential (ISO)

positive regulation of canonical Wnt signaling pathway (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of fat cell differentiation (ISO)

positive regulation of heart rate (ISO)

positive regulation of insulin secretion involved in cellular response to glucose stimulus (ISO)

positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization (ISO)

positive regulation of vasoconstriction (ISO)

protein homotetramerization (ISO)

protein sumoylation (ISO)

regulation of heart rate by cardiac conduction (ISO)

regulation of T cell cytokine production (ISO)

regulation of ventricular cardiac muscle cell action potential (ISO)

sodium ion import across plasma membrane (ISO)

Cellular Component

endoplasmic reticulum (ISO)

Golgi apparatus (ISO)

membrane (ISO)

neuronal cell body (ISO)

nucleoplasm (ISO)

plasma membrane (ISO)

sodium channel complex (ISO)

Molecular Function

ATP binding (ISO)

calcium channel activity (ISO)

calcium ion binding (ISO)

calcium-activated cation channel activity (ISO)

identical protein binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Trpm4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,546,365 - 1,581,712 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,539,036 - 1,581,800 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRPM4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,157,792 - 49,211,836 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,157,741 - 49,211,836 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	49,661,049 - 49,715,093 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,352,864 - 54,406,905 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	54,352,863 - 54,406,903	NCBI
Celera	19	46,527,963 - 46,581,978 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,037,071 - 46,092,109 (+)	NCBI		HuRef
CHM1_1	19	49,662,673 - 49,716,555 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,152,347 - 52,209,191 (+)	NCBI		T2T-CHM13v2.0

Trpm4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,952,579 - 44,983,495 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,952,056 - 44,983,204 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,303,155 - 45,334,071 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,302,632 - 45,333,780 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,558,525 - 52,589,150 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	45,170,674 - 45,201,784 (-)	NCBI		MGSCv36	mm8
Celera	7	40,759,067 - 40,790,038 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.24	NCBI

Trpm4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,918,462 - 104,949,453 (-)	NCBI		GRCr8
mRatBN7.2	1	95,781,805 - 95,812,095 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,782,000 - 95,812,532 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	101,167,413 - 101,197,191 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,640,086 - 109,669,864 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,930,482 - 102,960,268 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,293,300 - 101,323,484 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,293,409 - 101,323,960 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,357,043 - 102,387,010 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,773,485 - 95,803,542 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,851,812 - 95,863,602 (-)	NCBI
Celera	1	90,039,848 - 90,063,911 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

TRPM4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,272,183 - 55,328,155 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,191,713 - 57,248,153 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,168,301 - 46,224,726 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,095,029 - 55,150,464 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,095,029 - 55,150,464 (+)	Ensembl	panpan1.1		panPan2

TRPM4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,261,760 - 107,304,157 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,261,756 - 107,303,346 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,849,462 - 106,891,183 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,786,342 - 107,828,325 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,678,345 - 107,828,249 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,454,730 - 107,496,450 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	107,100,989 - 107,142,706 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,938,110 - 107,978,274 (-)	NCBI		UU_Cfam_GSD_1.0

Trpm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,474,889 - 21,506,283 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,093,367 - 3,124,117 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,093,258 - 3,124,473 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRPM4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,342,784 - 54,377,155 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,342,774 - 54,377,557 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	49,975,735 - 49,985,615 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRPM4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,379,534 - 42,424,721 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,379,659 - 42,424,146 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,272,664 - 22,341,345 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trpm4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,902,659 - 4,936,926 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,902,335 - 4,937,806 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005412902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005412903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01073648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01073649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01073650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01073651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01147170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000010203 ⟹ ENSCLAP00000010073

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955559	1,546,365 - 1,581,712 (-)	Ensembl

Ensembl Acc Id:

ENSCLAT00000010204 ⟹ ENSCLAP00000010074

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955559	1,546,365 - 1,578,053 (-)	Ensembl

RefSeq Acc Id:

XM_005412902 ⟹ XP_005412959

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955559	1,539,036 - 1,581,800 (-)	NCBI

Sequence:

show sequence

GCAGTGGCGGATCCGGTTTGGCTCAGGGCGGGGCTGGCGGGGCTGGCGGGGCTGCGAGGGTGAA
TGTGGGGAGCCCGGCGGCGGCAGAATGGTGGCCCCCGAGAAGGAGCAGAGCTGGATCCCCAAGA
TCTTCAGGAAGAAGATCTGCACCACGTTCATAGTCGACCTCTCGGACCCCGGAGGGACCCTGTG
CCAGTGCGGGCGCCCCCGGAAAGCCCACCCCTCGGTGGCCGTGGAGGACGCGTTCGGGGCAGCG
GTGGTGACCGTGTGGAGCAGTGATGTGCACACCACGGAGAAGCCCACCGACGCCTACGGCGAGC
TGGAGTTCCTGGGCGCCGGCCGCAGGCCCAGCAATTTCCTCCGGCTGTCTGACCGCACGGATCC
AGCAACTATTTATAGCTTGGTCACCCGAACATGGGGCTTTCGAGCCCCAAACCTGGTGGTGTCT
GTCCTGGGGGGTTCGGCGGGCCCCGTCCTCCAGACCTGGCTGCAGGACCTGCTAAGACGTGGGC
TAGTGCGGGCCGCCCAGAGCACAGGGGCCTGGATTGTCACCGGGGGGCTGCACTCCGGCATCGG
CAGGCACGTGGGCGTGGCAGTGCGGGACCACCAGACGGCCAGCACCGGCGGCAGCAAGGTGGTG
GCCATGGGTGTGGCACCCTGGGGCGTGGTCCGGAACCGAGACACCCTCACCAACCCCAAGGGCT
CCTTCCCTGCAAAGTACCGGTGGCGCGGCGACCCTGAGGATGGGGTGGAGTTCCCCCTGGACTA
CAACTACTCCGCCTTCTTCCTGGTGGACGACGGCACCCACGGCCGTGCGGGTGGCGAGGACCGA
TTCCGCCTGCGCTTCGAGTCCTACGTGGCGCAGCAGAAGACGGGCGTGGGCGGGACTGGAATTG
ACATCCCTGTCCTCCTCCTCCTGATCGATGGTGACGAGAGGATGCTGAAGCGGATAGAGGATGC
CACACAGGCCCAGCTCCCCTGCCTCCTGGTGGCTGGCTCTGGGGGTGCCGCCGACTGCCTGGCT
GAGACCCTGGAAGACTCTCTGGCCCCAGGGAGTGGGGGCACCAGGAGAGGTGAAGCCCGAGACC
GGATCAGGCGTTTCTTCCCCAAAGGGGACCCCGAGGTCCTGCAGGCCCAGGTGGAGAGGATCAT
GACCCGGAAGGAGTTGCTGACCGTCTATGCGTCGGAGGATGGCTCCGAGGAGTTCGAGACCATT
GTTTTGAAGGCCCTCGTGAAGGCCTGTGGGAGCTCCGAGGCCTCGGCCTACCTGGACGAGCTGC
GTCTGGCTGTGGCTTGGAACCGCGTGGACATCGCCCAGAGTGAACTCTTCCGAGGGGACATCCA
GTGGCGGTCCTTTCACCTGGAGGCGTCGCTCATGGACGCCCTGCTGAATGACCGGCCCGAGTTC
GTGCGCCTGCTCATCTCCCACGGCCTCAGCCTGGGCCACTTCCTCACGCCCGTGCGCCTGGCCC
AGCTCTACGGCGCGGCGCCCGCGCACTCGCTCATCCGCGCGCTGCTGGACCAGGCGGCCCACGG
GGCGGCCACCAAAGCCCCGGGGCACAAAGGGGGCGCTGAGGAGCCCCGGCCGCCTCAGGTGGGA
CAAGTACTGAGAACGCTGCTGGGGGAGACGTGCGCGCCGAAGTACCCCGCCGTGAACGCCCGGG
ACCCGCACACCGGCAAGGGCTGCAGAGAGAGCGTGTGTCTACTCTCGGATTGGGCCGCCTCGGA
ACCAGCGCTGGAAGCCAGCTTTGGGCAGGCGCCCTGGAGCGATCTCTTCCTCTGGGCACTGCTG
CTCAACAGAGCCCAGATGGCCATGTACTTCTGGGAGATGGGCTCCAACGCTGTGTCCTCTGCTC
TCGGGGCCTGCCTACTGCTCCGAGTGATGGCCCGCCAGGAAACCGAGACTGAGGAGGCGGCCCG
GCGGAAGGAGCTGGCGAGCAAGTTTGAGAGCATGGGTGTTGACCTCTTTGGGGAGTGCTACCGC
AGCAGCGAGACAAGGGCATCCCGCCTGCTTCTCCGTCGCTGTCCCCTCTGGGGCGACGCCACCT
GCCTCCAGCTTGCCATGCAGGCTGACGCTCGTGCCTTCCTTGCCCAGGATGGGGTCCAGTCTGT
GCTGACGCAGAAGTGGTGGGGGGAGATGGACAGCACCACCCCCACCTGGGCCCTGGTTCTCACC
TTCTTCTGCCCCCCACTGATCTACACCAACCTCATCGCCTTCAGGAAACTGGAAGAGGAGGCAA
CACAGAGGAGCCCTGGCGTTGACATGGACGGGGGCATTAATGGAGAGGGTCCCATTGGACCCAA
GGACCCTCTGGAGAAGGTGCAGCCGCCGGGCCGCGGGGGGCGCTGCTCGGGGCGCCGCTGCCTG
CGCCGCTGGTCGCGCTTCTGGGGGTCGCCGGTGACCGCCTTCCTGGGCAACGTGGTCAGCTACC
TGCTCTTCCTGCTGCTCTTCGCGCGCGTGCTGCTGATCGACTTCCAGCCTGGGCCGCCGTGCGC
CTGGGAGCTGCTGCTGTACTTCTGGGCCTTCACGCTGCTCTGCGAGGAGCTGCGCCAGGGCCTG
GGCGGCGGCTGGGGCAGCCTGGCCAGCGGGGGCCCCCGGCCCGGGCACATCCCGCTGCGCCGCC
GCCTGCAGCTCTATCTGGCCGACGCCTGGAACCAGTGCGACCTGCTGGCCCTCACCTGCTTCCT
GCTGGGCGTGGGCTGCCGGCTGACCGTGGGTCTGTATCACCTGGGCCGCACGGTGCTGTGTCTC
GACTTCATGATCTTCACGCTGCGGCTGCTACACATCTTCACTGTGAACAAGCAGCTGGGACCCA
AGATTGTCATCGTGAGCAAGATGATGAAAGATGTCTTCTTCTTCCTCTTCTTCCTCTGCGTCTG
GCTGGTCGCCTACGGCGTGGCCACTGAGGGGCTGCTAAGGCCCCAAGACCGTGATCTCCCCAGT
ATCCTGCGTCGGGTCTTCTACCGGCCCTACCTGCAGATCTTTGGGCAGATCCCCCAGGAGGACA
TGGATGTGGCCCTCATGACGCCCATGAACTGCTCCTCCGAGGAGGGCGCCTGGGCTCAGCCTCC
CGGGCGCCTGGCGGGCTCCTGCGTCTCCCTGTATGCCAACTGGCTAGTGGTGCTGCTCCTCGTC
ATCTTTCTGCTCGTGGCCAACATCCTGCTGCTCAATTTGCTCATCGCCATGTTCAGCTACACCT
TTGGCAAAGTACAGGGCAACAGTGACCTCTATTGGAAGGCACAACGCTATAGCCTCATCCGGGA
ATTCCACTCTCGGCCTGCACTGGCCCCGCCCCTCATCGTCATCTCCCACGTGCGACTCCTCATG
AGGCGCCTGTGTAGGAGCCGCCGCCGACGGTCCAGCACACCTGCCTCTCCGGCCATGGAGCACT
TTCGTGTCCACCTCTCCAAGGAGGCCGAGCGGACGCTGCTGACTTGGGAGTCGGTGCAGAAGGA
GAGCTTCCTGCTGGCCCGCACGCGGAACAAGCGGGACAGCGACTCTGAGCGGCTGAAGCGCACC
TCTCAGAAGGTGGACTTGGCGCTGAAGCAGCTGGGACAGATCCGGGAGTATGATCAACGTCTGA
AAGGGCTGGAGCGGGAGGTCCAGCACTGTGGCCGCGTCCTGGACTGGGTGGCCGAGGCCCTGAG
CCGCTCCACTGTGCTGCCACCGGGCGGGCCACCGCCCCCTGCACGGCCCAGCTCGAAAGAAAGA
GTCTTCTGGCCCCTATCATAGCTGGAACTACTTGCTGATGCTACACACATCTTAACCAAGACAA
AGCGCTGGGGACCCCAGTGGAGTCTGTATCAGTCAGGGTTTACTAGAGGAACAGATATAATACA
AGATAAACAAATGTACAAGAAATTACAAG

hide sequence

RefSeq Acc Id:

XM_005412903 ⟹ XP_005412960

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955559	1,545,889 - 1,581,800 (-)	NCBI

Sequence:

show sequence

GCAGTGGCGGATCCGGTTTGGCTCAGGGCGGGGCTGGCGGGGCTGGCGGGGCTGCGAGGGTGAA
TGTGGGGAGCCCGGCGGCGGCAGAATGGTGGCCCCCGAGAAGGAGCAGAGCTGGATCCCCAAGA
TCTTCAGGAAGAAGATCTGCACCACGTTCATAGTCGACCTCTCGGACCCCGGAGGGACCCTGTG
CCAGTGCGGGCGCCCCCGGAAAGCCCACCCCTCGGTGGCCGTGGAGGACGCGTTCGGGGCAGCG
GTGGTGACCGTGTGGAGCAGTGATGTGCACACCACGGAGAAGCCCACCGACGCCTACGGCGAGC
TGGAGTTCCTGGGCGCCGGCCGCAGGCCCAGCAATTTCCTCCGGCTGTCTGACCGCACGGATCC
AGCAACTATTTATAGCTTGGTCACCCGAACATGGGGCTTTCGAGCCCCAAACCTGGTGGTGTCT
GTCCTGGGGGGTTCGGCGGGCCCCGTCCTCCAGACCTGGCTGCAGGACCTGCTAAGACGTGGGC
TAGTGCGGGCCGCCCAGAGCACAGGGGCCTGGATTGTCACCGGGGGGCTGCACTCCGGCATCGG
CAGGCACGTGGGCGTGGCAGTGCGGGACCACCAGACGGCCAGCACCGGCGGCAGCAAGGTGGTG
GCCATGGGTGTGGCACCCTGGGGCGTGGTCCGGAACCGAGACACCCTCACCAACCCCAAGGGCT
CCTTCCCTGCAAAGTACCGGTGGCGCGGCGACCCTGAGGATGGGGTGGAGTTCCCCCTGGACTA
CAACTACTCCGCCTTCTTCCTGGTGGACGACGGCACCCACGGCCGTGCGGGTGGCGAGGACCGA
TTCCGCCTGCGCTTCGAGTCCTACGTGGCGCAGCAGAAGACGGGCGTGGGCGGGACTGGAATTG
ACATCCCTGTCCTCCTCCTCCTGATCGATGGTGACGAGAGGATGCTGAAGCGGATAGAGGATGC
CACACAGGCCCAGCTCCCCTGCCTCCTGGTGGCTGGCTCTGGGGGTGCCGCCGACTGCCTGGCT
GAGACCCTGGAAGACTCTCTGGCCCCAGGGAGTGGGGGCACCAGGAGAGGTGAAGCCCGAGACC
GGATCAGGCGTTTCTTCCCCAAAGGGGACCCCGAGGTCCTGCAGGCCCAGGTGGAGAGGATCAT
GACCCGGAAGGAGTTGCTGACCGTCTATGCGTCGGAGGATGGCTCCGAGGAGTTCGAGACCATT
GTTTTGAAGGCCCTCGTGAAGGCCTGTGGGAGCTCCGAGGCCTCGGCCTACCTGGACGAGCTGC
GTCTGGCTGTGGCTTGGAACCGCGTGGACATCGCCCAGAGTGAACTCTTCCGAGGGGACATCCA
GTGGCGGTCCTTTCACCTGGAGGCGTCGCTCATGGACGCCCTGCTGAATGACCGGCCCGAGTTC
GTGCGCCTGCTCATCTCCCACGGCCTCAGCCTGGGCCACTTCCTCACGCCCGTGCGCCTGGCCC
AGCTCTACGGCGCGGCGCCCGCGCACTCGCTCATCCGCGCGCTGCTGGACCAGGCGGCCCACGG
GGCGGCCACCAAAGCCCCGGGGCACAAAGGGGGCGCTGAGGAGCCCCGGCCGCCTCAGGTGGGA
CAAGTACTGAGAACGCTGCTGGGGGAGACGTGCGCGCCGAAGTACCCCGCCGTGAACGCCCGGG
ACCCGCACACCGGCAAGGGCTGCAGAGAGAGCGTGTGTCTACTCTCGGATTGGGCCGCCTCGGA
ACCAGCGCTGGAAGCCAGCTTTGGGCAGGCGCCCTGGAGCGATCTCTTCCTCTGGGCACTGCTG
CTCAACAGAGCCCAGATGGCCATGTACTTCTGGGAGATGGGCTCCAACGCTGTGTCCTCTGCTC
TCGGGGCCTGCCTACTGCTCCGAGTGATGGCCCGCCAGGAAACCGAGACTGAGGAGGCGGCCCG
GCGGAAGGAGCTGGCGAGCAAGTTTGAGAGCATGGGTGTTGACCTCTTTGGGGAGTGCTACCGC
AGCAGCGAGACAAGGGCATCCCGCCTGCTTCTCCGTCGCTGTCCCCTCTGGGGCGACGCCACCT
GCCTCCAGCTTGCCATGCAGGCTGACGCTCGTGCCTTCCTTGCCCAGGATGGGGTCCAGTCTGT
GCTGACGCAGAAGTGGTGGGGGGAGATGGACAGCACCACCCCCACCTGGGCCCTGGTTCTCACC
TTCTTCTGCCCCCCACTGATCTACACCAACCTCATCGCCTTCAGGAAACTGGAAGAGGAGGCAA
CACAGAGGAGCCCTGGCGTTGACATGGACGGGGGCATTAATGGAGAGGGTCCCATTGGACCCAA
GGACCCTCTGGAGAAGGTGCAGCCGCCGGGCCGCGGGGGGCGCTGCTCGGGGCGCCGCTGCCTG
CGCCGCTGGTCGCGCTTCTGGGGGTCGCCGGTGACCGCCTTCCTGGGCAACGTGGTCAGCTACC
TGCTCTTCCTGCTGCTCTTCGCGCGCGTGCTGCTGATCGACTTCCAGCCTGGGCCGCCGTGCGC
CTGGGAGCTGCTGCTGTACTTCTGGGCCTTCACGCTGCTCTGCGAGGAGCTGCGCCAGGGCCTG
GGCGGCGGCTGGGGCAGCCTGGCCAGCGGGGGCCCCCGGCCCGGGCACATCCCGCTGCGCCGCC
GCCTGCAGCTCTATCTGGCCGACGCCTGGAACCAGTGCGACCTGCTGGCCCTCACCTGCTTCCT
GCTGGGCGTGGGCTGCCGGCTGACCGTGGGTCTGTATCACCTGGGCCGCACGGTGCTGTGTCTC
GACTTCATGATCTTCACGCTGCGGCTGCTACACATCTTCACTGTGAACAAGCAGCTGGGACCCA
AGATTGTCATCGTGAGCAAGATGATGAAAGATGTCTTCTTCTTCCTCTTCTTCCTCTGCGTCTG
GCTGGTCGCCTACGGCGTGGCCACTGAGGGGCTGCTAAGGCCCCAAGACCGTGATCTCCCCAGT
ATCCTGCGTCGGGTCTTCTACCGGCCCTACCTGCAGATCTTTGGGCAGATCCCCCAGGAGGACA
TGGATGTGGCCCTCATGACGCCCATGAACTGCTCCTCCGAGGAGGGCGCCTGGGCTCAGCCTCC
CGGGCGCCTGGCGGGCTCCTGCGTCTCCCTGTATGCCAACTGGCTAGTGGTGCTGCTCCTCGTC
ATCTTTCTGCTCGTGGCCAACATCCTGCTGCTCAATTTGCTCATCGCCATGTTCAGCTACACCT
TTGGCAAAGTACAGGGCAACAGTGACCTCTATTGGAAGGCACAACGCTATAGCCTCATCCGGGA
ATTCCACTCTCGGCCTGCACTGGCCCCGCCCCTCATCGTCATCTCCCACGTGCGACTCCTCATG
AGGCGCCTGTGTAGGAGCCGCCGCCGACGGTCCAGCACACCTGCCTCTCCGGCCATGGAGCACT
TTCGTGTCCACCTCTCCAAGGAGGCCGAGCGGACGCTGCTGACTTGGGAGTCGGTGCAGAAGGA
GAGCTTCCTGCTGGCCCGCACGCGGAACAAGCGGGACAGCGACTCTGAGCGGCTGAAGCGCACC
TCTCAGAAGGTGGACTTGGCGCTGAAGCAGCTGGGACAGATCCGGGAGTATGATCAACGTCTGA
AAGGGCTGGAGCGGGAGGTCCAGCACTGTGGCCGCGTCCTGGACTGGGTGGCCGAGGCCCTGAG
CCGCTCCACTGTGCTGCCACCGGGCGGGCCACCGCCCCCTGCACGGCCCAGCTCGAAAGACTGA
GCGCTGCTGGCCTTCACGGAGTGGCCCCCAGGGTCCTGCTCCTGGACCAAGGCCCAGGCGGCCC
CACCTGTGTGCCCGACGGCCTTGTCCCTGAGCTGGGCCAGGTTCAGGGACCACGGTGGGGACAC
CCTGGGGAGTGTCGCCCATGCGAGCACGCAGGCGCGGCTCCTCCCAGCACCAGCCCCGCCGTGG
GAGGATCAGGGTGTGCGGCGCAGGCTGCCGACCCCCGGAGGGACCTGCCCCAGTGGGGGCCACA
GGGGGGTCCTTGGGGCAACGGGGACCACTGACCCTATTCCAAGCTTCCCCACACTGGGGAAATA
AAGCCTGTGAGATCAGTAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005412959	(Get FASTA)	NCBI Sequence Viewer
	XP_005412960	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010073
	ENSCLAP00000010073.1
	ENSCLAP00000010074.1

RefSeq Acc Id:	XP_005412959 ⟸ XM_005412902
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2V7U6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAPEKEQSWIPKIFRKKICTTFIVDLSDPGGTLCQCGRPRKAHPSVAVEDAFGAAVVTVWSSD VHTTEKPTDAYGELEFLGAGRRPSNFLRLSDRTDPATIYSLVTRTWGFRAPNLVVSVLGGSAGP VLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHSGIGRHVGVAVRDHQTASTGGSKVVAMGVAPWG VVRNRDTLTNPKGSFPAKYRWRGDPEDGVEFPLDYNYSAFFLVDDGTHGRAGGEDRFRLRFESY VAQQKTGVGGTGIDIPVLLLLIDGDERMLKRIEDATQAQLPCLLVAGSGGAADCLAETLEDSLA PGSGGTRRGEARDRIRRFFPKGDPEVLQAQVERIMTRKELLTVYASEDGSEEFETIVLKALVKA CGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHG LSLGHFLTPVRLAQLYGAAPAHSLIRALLDQAAHGAATKAPGHKGGAEEPRPPQVGQVLRTLLG ETCAPKYPAVNARDPHTGKGCRESVCLLSDWAASEPALEASFGQAPWSDLFLWALLLNRAQMAM YFWEMGSNAVSSALGACLLLRVMARQETETEEAARRKELASKFESMGVDLFGECYRSSETRASR LLLRRCPLWGDATCLQLAMQADARAFLAQDGVQSVLTQKWWGEMDSTTPTWALVLTFFCPPLIY TNLIAFRKLEEEATQRSPGVDMDGGINGEGPIGPKDPLEKVQPPGRGGRCSGRRCLRRWSRFWG SPVTAFLGNVVSYLLFLLLFARVLLIDFQPGPPCAWELLLYFWAFTLLCEELRQGLGGGWGSLA SGGPRPGHIPLRRRLQLYLADAWNQCDLLALTCFLLGVGCRLTVGLYHLGRTVLCLDFMIFTLR LLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGLLRPQDRDLPSILRRVFYR PYLQIFGQIPQEDMDVALMTPMNCSSEEGAWAQPPGRLAGSCVSLYANWLVVLLLVIFLLVANI LLLNLLIAMFSYTFGKVQGNSDLYWKAQRYSLIREFHSRPALAPPLIVISHVRLLMRRLCRSRR RRSSTPASPAMEHFRVHLSKEAERTLLTWESVQKESFLLARTRNKRDSDSERLKRTSQKVDLAL KQLGQIREYDQRLKGLEREVQHCGRVLDWVAEALSRSTVLPPGGPPPPARPSSKERVFWPLS hide sequence

RefSeq Acc Id:	XP_005412960 ⟸ XM_005412903
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2V7U6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVAPEKEQSWIPKIFRKKICTTFIVDLSDPGGTLCQCGRPRKAHPSVAVEDAFGAAVVTVWSSD VHTTEKPTDAYGELEFLGAGRRPSNFLRLSDRTDPATIYSLVTRTWGFRAPNLVVSVLGGSAGP VLQTWLQDLLRRGLVRAAQSTGAWIVTGGLHSGIGRHVGVAVRDHQTASTGGSKVVAMGVAPWG VVRNRDTLTNPKGSFPAKYRWRGDPEDGVEFPLDYNYSAFFLVDDGTHGRAGGEDRFRLRFESY VAQQKTGVGGTGIDIPVLLLLIDGDERMLKRIEDATQAQLPCLLVAGSGGAADCLAETLEDSLA PGSGGTRRGEARDRIRRFFPKGDPEVLQAQVERIMTRKELLTVYASEDGSEEFETIVLKALVKA CGSSEASAYLDELRLAVAWNRVDIAQSELFRGDIQWRSFHLEASLMDALLNDRPEFVRLLISHG LSLGHFLTPVRLAQLYGAAPAHSLIRALLDQAAHGAATKAPGHKGGAEEPRPPQVGQVLRTLLG ETCAPKYPAVNARDPHTGKGCRESVCLLSDWAASEPALEASFGQAPWSDLFLWALLLNRAQMAM YFWEMGSNAVSSALGACLLLRVMARQETETEEAARRKELASKFESMGVDLFGECYRSSETRASR LLLRRCPLWGDATCLQLAMQADARAFLAQDGVQSVLTQKWWGEMDSTTPTWALVLTFFCPPLIY TNLIAFRKLEEEATQRSPGVDMDGGINGEGPIGPKDPLEKVQPPGRGGRCSGRRCLRRWSRFWG SPVTAFLGNVVSYLLFLLLFARVLLIDFQPGPPCAWELLLYFWAFTLLCEELRQGLGGGWGSLA SGGPRPGHIPLRRRLQLYLADAWNQCDLLALTCFLLGVGCRLTVGLYHLGRTVLCLDFMIFTLR LLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLCVWLVAYGVATEGLLRPQDRDLPSILRRVFYR PYLQIFGQIPQEDMDVALMTPMNCSSEEGAWAQPPGRLAGSCVSLYANWLVVLLLVIFLLVANI LLLNLLIAMFSYTFGKVQGNSDLYWKAQRYSLIREFHSRPALAPPLIVISHVRLLMRRLCRSRR RRSSTPASPAMEHFRVHLSKEAERTLLTWESVQKESFLLARTRNKRDSDSERLKRTSQKVDLAL KQLGQIREYDQRLKGLEREVQHCGRVLDWVAEALSRSTVLPPGGPPPPARPSSKD hide sequence

Ensembl Acc Id:

ENSCLAP00000010073 ⟸ ENSCLAT00000010203

Ensembl Acc Id:

ENSCLAP00000010074 ⟸ ENSCLAT00000010204

Protein Domains

Ion transport TRPM SLOG

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000006981	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000010203	ENTREZGENE
	ENSCLAT00000010203.1	UniProtKB/TrEMBL
	ENSCLAT00000010204.1	UniProtKB/TrEMBL
InterPro	Ion_trans_dom	UniProtKB/TrEMBL
	TRPM	UniProtKB/TrEMBL
	TRPM_SLOG	UniProtKB/TrEMBL
NCBI Gene	Trpm4	ENTREZGENE
PANTHER	PTHR13800:SF6	UniProtKB/TrEMBL
	TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6	UniProtKB/TrEMBL
Pfam	Ion_trans	UniProtKB/TrEMBL
	LSDAT_euk	UniProtKB/TrEMBL
Superfamily-SCOP	Pseudo ankyrin repeat-like	UniProtKB/TrEMBL
UniProt	A0A8C2V7U6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2VAF2_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-03	Trpm4	transient receptor potential cation channel subfamily M member 4		transient receptor potential cation channel, subfamily M, member 4	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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