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Gene: Gba1 (glucosylceramidase beta 1) Chinchilla lanigera

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Symbol:

Gba1

Name:

glucosylceramidase beta 1

RGD ID:

8939279

Description:

ENCODES a protein that exhibits beta-glucosidase activity (ortholog); glucosylceramidase activity (ortholog); glucosyltransferase activity (ortholog); INVOLVED IN antigen processing and presentation (ortholog); autophagosome organization (ortholog); autophagy (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH alpha thalassemia-X-linked intellectual disability syndrome (ortholog); Autosomal Dominant Diffuse Lewy Body Disease (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); FOUND IN endoplasmic reticulum (ortholog); extracellular space (ortholog); Golgi apparatus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Gba; glucosidase, beta, acid; glucosylceramidase; glucosylceramidase beta

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,682,097 - 1,689,376 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,682,097 - 1,689,373 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alpha thalassemia-X-linked intellectual disability syndrome (ISO)

Autosomal Dominant Diffuse Lewy Body Disease (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

gastrointestinal stromal tumor (ISO)

Gaucher's disease (ISO)

Gaucher's disease perinatal lethal (ISO)

Gaucher's disease type I (ISO)

Gaucher's disease type II (ISO)

Gaucher's disease type III (ISO)

Gaucher's disease type IIIC (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

hepatoblastoma (ISO)

immunodeficiency 42 (ISO)

Inflammation (ISO)

late onset Parkinson's disease (ISO)

Lewy body dementia (ISO)

MHC class II deficiency (ISO)

movement disease (ISO)

Netherton syndrome (ISO)

parathyroid carcinoma (ISO)

Parkinson's disease (ISO)

Parkinsonism (ISO)

psoriasis (ISO)

pulmonary hypertension (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

thrombocytopenia (ISO)

Tremor (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation (ISO)

autophagosome organization (ISO)

autophagy (ISO)

beta-glucoside catabolic process (ISO)

brain morphogenesis (ISO)

cell maturation (ISO)

cellular response to starvation (ISO)

cellular response to tumor necrosis factor (ISO)

central nervous system development (ISO)

ceramide biosynthetic process (ISO)

cerebellar Purkinje cell layer formation (ISO)

cholesterol metabolic process (ISO)

determination of adult lifespan (ISO)

establishment of skin barrier (ISO)

glucosylceramide catabolic process (ISO)

glucosylceramide metabolic process (ISO)

hematopoietic stem cell proliferation (ISO)

homeostasis of number of cells (ISO)

lipid glycosylation (ISO)

lipid storage (ISO)

lymphocyte migration (ISO)

lysosomal protein catabolic process (ISO)

lysosome organization (ISO)

microglia differentiation (ISO)

microglial cell proliferation (ISO)

mitochondrion organization (ISO)

mitophagy (ISO)

motor behavior (ISO)

negative regulation of inflammatory response (ISO)

negative regulation of interleukin-6 production (ISO)

negative regulation of MAPK cascade (ISO)

negative regulation of neuron apoptotic process (ISO)

negative regulation of protein metabolic process (ISO)

negative regulation of protein-containing complex assembly (ISO)

nervous system process (ISO)

neuromuscular process (ISO)

neuron apoptotic process (ISO)

neuron projection development (ISO)

positive regulation of neuronal action potential (ISO)

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO)

positive regulation of proteolysis involved in protein catabolic process (ISO)

positive regulation of type 2 mitophagy (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (ISO)

pyramidal neuron differentiation (ISO)

regulation of membrane potential (ISO)

regulation of protein metabolic process (ISO)

regulation of TOR signaling (ISO)

respiratory electron transport chain (ISO)

response to dexamethasone (ISO)

response to estrogen (ISO)

response to pH (ISO)

response to testosterone (ISO)

response to thyroid hormone (ISO)

skin epidermis development (ISO)

sphingosine biosynthetic process (ISO)

T cell differentiation in thymus (ISO)

termination of signal transduction (ISO)

Cellular Component

endoplasmic reticulum (ISO)

extracellular space (ISO)

Golgi apparatus (ISO)

lysosomal lumen (ISO)

lysosomal membrane (ISO)

lysosome (ISO)

trans-Golgi network (ISO)

Molecular Function

beta-glucosidase activity (ISO)

glucosylceramidase activity (ISO)

glucosyltransferase activity (ISO)

hydrolase activity (ISO)

protein binding (ISO)

scavenger receptor binding (ISO)

signaling receptor binding (ISO)

steryl-beta-glucosidase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Fabry disease pathway (ISO)

Gaucher's disease pathway (ISO)

Krabbe disease pathway (ISO)

metachromatic leukodystrophy pathway (ISO)

Parkinson's disease pathway (ISO)

sphingolipid metabolic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Gba1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	1,682,097 - 1,689,376 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	1,682,097 - 1,689,373 (-)	NCBI	ChiLan1.0	ChiLan1.0

GBA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	155,234,452 - 155,244,627 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	155,234,452 - 155,244,699 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	155,204,243 - 155,214,418 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	153,470,867 - 153,481,112 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	128,277,514 - 128,287,929 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI
HuRef	1	126,567,152 - 126,576,952 (-)	NCBI		HuRef
CHM1_1	1	156,599,733 - 156,610,147 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	154,373,009 - 154,383,185 (-)	NCBI		T2T-CHM13v2.0

Gba1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	89,110,235 - 89,119,944 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	89,110,235 - 89,116,273 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	89,202,905 - 89,208,873 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	89,202,928 - 89,208,966 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	89,006,850 - 89,012,603 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	89,288,867 - 89,294,608 (+)	NCBI		MGSCv36	mm8
Celera	3	89,236,609 - 89,242,363 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.01	NCBI

Gba1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	176,902,141 - 176,916,015 (+)	NCBI		GRCr8
mRatBN7.2	2	174,609,437 - 174,615,457 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	174,609,403 - 174,618,263 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	181,755,295 - 181,761,307 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	179,777,667 - 179,783,679 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	174,377,514 - 174,383,527 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	188,511,781 - 188,522,602 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	188,516,582 - 188,522,601 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	207,931,042 - 207,937,062 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	2	168,551,737 - 168,557,757 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

GBA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	94,599,104 - 94,609,710 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	94,330,442 - 94,341,057 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	130,579,300 - 130,589,560 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	134,185,385 - 134,194,851 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	134,185,385 - 134,194,851 (-)	Ensembl	panpan1.1		panPan2

GBA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	42,317,704 - 42,322,285 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	42,317,862 - 42,322,864 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	41,808,580 - 41,813,161 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	42,186,904 - 42,191,488 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	42,186,929 - 42,191,486 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	41,966,726 - 41,971,306 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	42,020,650 - 42,025,231 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	42,304,204 - 42,308,788 (+)	NCBI		UU_Cfam_GSD_1.0

Gba1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	25,685,030 - 25,690,379 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	4,715,408 - 4,720,798 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	4,715,869 - 4,720,752 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GBA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	94,584,134 - 94,609,745 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	94,583,905 - 94,606,689 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	103,366,844 - 103,389,270 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	4	q21	NCBI

GBA1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	8,598,110 - 8,631,517 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	8,598,628 - 8,630,990 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	7,943,329 - 7,948,511 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gba1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	2,315,142 - 2,321,327 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	2,315,371 - 2,321,327 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005411586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01071867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDJ01186339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000007890 ⟹ ENSCLAP00000007770

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955545	1,682,097 - 1,689,376 (-)	Ensembl

RefSeq Acc Id:

XM_005411586 ⟹ XP_005411643

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955545	1,682,097 - 1,689,373 (-)	NCBI

Sequence:

show sequence

AGGACCGGAATTGACCTGCAGGGCTAGTCAGGTCCCTATGGCTGCAGTATATACGTGCATACTT
GTTTTTATTTCGTGAATCCGCTCATCTTTCCGAGACTCTGGACCTCCTGCAGGCTTCTCTTCAT
CCAGTAACCAGATGTGATGGAGTTTTCAGGTCCTTCCATAGAGGAACATCCCAAATGCCTGGGC
AGGGTAGGCATCATGGCTGCCAGCCTCACGGGATTGCTCCTGCTTCAGGCAGTGGCATGGGCAT
CAGGTGCCTACCCCTGTGTCCCTAAAAGCTTTGGCTACAGCTCAGTGGTCTGTGTCTGCAATGC
TACGTACTGCGACTCTCTTGATCCCTTGACCCTCCCAGCCTTGGGGACCTTCAGCCGCTATGAG
AGTACGCGCAGTGGACGTCGGATGGAGCTGAGTGTGGGTGACTTCCAGGCCAACCGCACCGGCA
CAGGGCTTCTATTGACCCTGCAGCCAGAAGAGAAGTTCCAGAAAGTGAAAGGATTTGGAGGGGC
CATGACAGATGCTGCTGCTCTCAATATCCTCGCCCTGTCACCCCCTGCCCAGAATTTGCTACTG
AAATCATACTTCTCTAAAGAAGGGATTGAATATAACATCATCCGGGTACCCATGGCTAGCTGTG
ACTTCTCCATCCGCACCTATACCTATGATGACACCCCTGATGACTTCCAGTTGCACAATTTCAG
CCTCACAGAAGAAGATACCAAGCTCAAGATACCCTTGATTCACCGAGCCCTGCAAATGTCCCAG
CGTCCTGTCTCACTCTTCGCCAGTCCCTGGACATCACCCACTTGGCTCAAGACCAATGGGGCAG
TGAATGGGAAGGGGACACTCAAGGGGACGCCAGGGGACATCTACCACCAGACCTGGGCCAAGTA
CTTTGTCAAGTTCCTGGATGCCTATGCTGAGCACAAGTTAAAGTTCTGGGCAGTGACAGTTGAG
AATGAGCCTTCTGCAGGGCTGATGAGTGGTTACCCCTTCCAGTGTCTGGGCTTCACCCCTGAAC
ACCAGCGAGATTTCATTGCCCGTGACCTGGGTCCAACCCTTGCTAACAGTACTCATCGTGACAT
CCAGCTGATCATGCTGGATGACAACCGATTGCTGCTGCCTCACTGGGCACAGGTGGTGCTGACA
GACCAACAAGCAGCTAAGTATGTCAGCGGGATTGCTGTGCACTGGTACCTGGACTTCCTGGCGC
CAGCAAAAGCTACTCTGGGAGCAACGCACCGCTTGTTCCCTGACACCATGCTCTTCGCCTCAGA
GGCCTGTGTGGGCTCCAAGTTCTGGGAGCAGAGCGTGCGACTGGGCTCCTGGGATCGCGGGATG
CAGTACAGCAACAGCATCATCACGAACCTCCTCTATCACGTGGTTGGCTGGACTGACTGGAACC
TCGCCCTGAACCCTGAGGGGGGACCTAACTGGGTCCGCAACTTTGTTGACAGCCCCATCATTGT
AGATATTGCCAAGGACACGTTTTACAAACAGCCCATGTTCTATCACCTTGGCCACTTCAGCAAG
TTCATTCCTGAGGGGTCGCAGCGAGTGGGGCTGGTGGCCAGTGAGGAGAACGACTTGGAGGCCG
TGGCACTACTGCATCCTGACGGCTCTGCAGTTGTGGTTGTGCTGAACCGCTCCTCTAGAGATGT
GCGTCTCAGCATTAAGGACCCTGCCATTGGCTTCCTAGAGACCATCTCCCCTGGCTACTCCATT
CACACCTACCTGTGGCGTCGACAGTGATGGAACAGATACCCAAGCAGGCACCTGGGCCTGGCAT
GGGTGCTAAAGAGACACAGTCAGCTCATATGCTGAGTAAAGGAAGTGGCTAAGAGGGTACAGCA
GGGCCAGGGTGGGCTCACAGTGACACAAGCCCAGGGGCAGTGATTGGGTGACTCACTCTCCTCT
TTACTGGGTGCCAGGGGCTGGAAGCCCCTAGGGAAAGATTAGGAAACCCCGGTATCTCCGACCC
CATGCTTGTGTAGGAGTGTGCTGTGTGCTGGTTGCCTGTGGAAACTGGGCTCAGGCCCAGGGTG
AGCTCACTGTCTGTACAAACACAAGACTGGGGTGGGGGGAGGAAAGAAGAGATTAAGAAAGCTG
GACCCAAAAATGGGGACTGTTTGTCTTTCCTGAAGATGCAGAACTGGGCCCATGCAGAAGCAGT
GTCAGCATCAAGGCAGAAACAGCCACAGAAGCCAAGGCCACTGCGTATGCTCAGGCACCCAAAT
GCTCCTGTGCTACTGGCTGGGAAATGTCAGTCCCTTAAAACAGAATGTTTGGCCTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005411643	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000007770
	ENSCLAP00000007770.1

RefSeq Acc Id:

XP_005411643 ⟸ XM_005411586

- UniProtKB:

A0A8C2V123 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEFSGPSIEEHPKCLGRVGIMAASLTGLLLLQAVAWASGAYPCVPKSFGYSSVVCVCNATYCDS
LDPLTLPALGTFSRYESTRSGRRMELSVGDFQANRTGTGLLLTLQPEEKFQKVKGFGGAMTDAA
ALNILALSPPAQNLLLKSYFSKEGIEYNIIRVPMASCDFSIRTYTYDDTPDDFQLHNFSLTEED
TKLKIPLIHRALQMSQRPVSLFASPWTSPTWLKTNGAVNGKGTLKGTPGDIYHQTWAKYFVKFL
DAYAEHKLKFWAVTVENEPSAGLMSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHRDIQLIML
DDNRLLLPHWAQVVLTDQQAAKYVSGIAVHWYLDFLAPAKATLGATHRLFPDTMLFASEACVGS
KFWEQSVRLGSWDRGMQYSNSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDIAKD
TFYKQPMFYHLGHFSKFIPEGSQRVGLVASEENDLEAVALLHPDGSAVVVVLNRSSRDVRLSIK
DPAIGFLETISPGYSIHTYLWRRQ

hide sequence

Ensembl Acc Id:

ENSCLAP00000007770 ⟸ ENSCLAT00000007890

Protein Domains

Glycosyl hydrolase family 30 beta sandwich Glycosyl hydrolase family 30 TIM-barrel

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000005452	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000007890	ENTREZGENE
	ENSCLAT00000007890.1	UniProtKB/TrEMBL
Gene3D-CATH	Glycosidases	UniProtKB/TrEMBL
InterPro	GH30_C	UniProtKB/TrEMBL
	Glyco_hydro_30	UniProtKB/TrEMBL
	Glyco_hydro_30_TIM-barrel	UniProtKB/TrEMBL
	Glycoside_hydrolase_SF	UniProtKB/TrEMBL
NCBI Gene	Gba	ENTREZGENE
PANTHER	LYSOSOMAL ACID GLUCOSYLCERAMIDASE	UniProtKB/TrEMBL
	PTHR11069	UniProtKB/TrEMBL
Pfam	Glyco_hydro_30	UniProtKB/TrEMBL
	Glyco_hydro_30C	UniProtKB/TrEMBL
PRINTS	GLHYDRLASE30	UniProtKB/TrEMBL
Superfamily-SCOP	Glycosyl hydrolase domain	UniProtKB/TrEMBL
	SSF51445	UniProtKB/TrEMBL
UniProt	A0A8C2V123	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-21	Gba1	glucosylceramidase beta 1	Gba	glucosylceramidase beta	Symbol and/or name change	5135510	APPROVED
2016-08-03	Gba	glucosylceramidase beta		glucosidase, beta, acid	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB