Aqp1 (aquaporin 1 (Colton blood group)) - Rat Genome Database

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Gene: Aqp1 (aquaporin 1 (Colton blood group)) Chinchilla lanigera
Analyze
Symbol: Aqp1
Name: aquaporin 1 (Colton blood group)
RGD ID: 8908628
Description: ENCODES a protein that exhibits ammonium channel activity (ortholog); carbon dioxide transmembrane transporter activity (ortholog); ephrin receptor binding (ortholog); INVOLVED IN ammonium transmembrane transport (ortholog); camera-type eye morphogenesis (ortholog); carbon dioxide transmembrane transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Animal Mammary Neoplasms (ortholog); Aquaporin 1 Deficiency (ortholog); FOUND IN ankyrin-1 complex (ortholog); apical part of cell (ortholog); apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: aquaporin-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,066,196 - 32,078,717 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541032,066,196 - 32,078,661 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
ammonium transmembrane transport  (ISO)
camera-type eye morphogenesis  (ISO)
carbon dioxide transmembrane transport  (ISO)
carbon dioxide transport  (ISO)
cell migration  (ISO)
cell volume homeostasis  (ISO)
cellular homeostasis  (ISO)
cellular hyperosmotic response  (ISO)
cellular response to cAMP  (ISO)
cellular response to copper ion  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to mercury ion  (ISO)
cellular response to nitric oxide  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to salt stress  (ISO)
cellular response to UV  (ISO)
cerebrospinal fluid secretion  (ISO)
cGMP-mediated signaling  (ISO)
corticotropin secretion  (ISO)
defense response to Gram-negative bacterium  (ISO)
establishment of localization in cell  (ISO)
establishment or maintenance of actin cytoskeleton polarity  (ISO)
fibroblast migration  (ISO)
glomerular filtration  (ISO)
glycerol transmembrane transport  (ISO)
hyperosmotic response  (ISO)
intracellular water homeostasis  (ISO)
lateral ventricle development  (ISO)
lipid digestion  (ISO)
metanephric descending thin limb development  (ISO)
metanephric glomerulus vasculature development  (ISO)
metanephric proximal convoluted tubule segment 2 development  (ISO)
metanephric proximal straight tubule development  (ISO)
metanephric proximal tubule development  (ISO)
multicellular organismal-level water homeostasis  (ISO)
negative regulation of apoptotic process  (ISO)
nitric oxide transport  (ISO)
odontogenesis  (ISO)
pancreatic juice secretion  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of epithelial cell migration  (ISO)
positive regulation of fibroblast migration  (ISO)
positive regulation of fibroblast proliferation  (ISO)
positive regulation of lamellipodium assembly  (ISO)
positive regulation of saliva secretion  (ISO)
potassium ion transport  (ISO)
renal water absorption  (ISO)
renal water transport  (ISO)
response to estrogen  (ISO)
response to hormone  (ISO)
secretion by cell  (ISO)
secretory granule organization  (ISO)
sensory perception of pain  (ISO)
transepithelial water transport  (ISO)
water transport  (ISO)
wound healing  (ISO)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Aqp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541032,066,196 - 32,078,717 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541032,066,196 - 32,078,661 (+)NCBIChiLan1.0ChiLan1.0
AQP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38730,911,853 - 30,925,516 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl730,911,853 - 30,925,517 (+)EnsemblGRCh38hg38GRCh38
GRCh37730,951,468 - 30,965,131 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36730,917,993 - 30,931,656 (+)NCBINCBI36Build 36hg18NCBI36
Build 34730,724,707 - 30,738,371NCBI
Celera730,940,621 - 30,954,337 (+)NCBICelera
Cytogenetic Map7p14.3NCBI
HuRef730,833,637 - 30,847,351 (+)NCBIHuRef
CHM1_1730,951,350 - 30,965,064 (+)NCBICHM1_1
T2T-CHM13v2.0731,049,501 - 31,063,163 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2731,000,921 - 31,014,637 (+)NCBI
Aqp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39655,313,284 - 55,325,540 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl655,313,417 - 55,325,540 (+)EnsemblGRCm39 Ensembl
GRCm38655,336,299 - 55,348,555 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl655,336,432 - 55,348,555 (+)EnsemblGRCm38mm10GRCm38
MGSCv37655,286,293 - 55,298,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36655,266,010 - 55,278,133 (+)NCBIMGSCv36mm8
Celera655,870,108 - 55,882,362 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map627.38NCBI
Aqp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8485,812,784 - 85,824,964 (+)NCBIGRCr8
mRatBN7.2484,482,512 - 84,494,690 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl484,482,512 - 84,494,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx489,700,946 - 89,713,083 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0485,476,356 - 85,488,493 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0483,882,115 - 83,894,263 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0485,551,503 - 85,563,683 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl485,551,502 - 85,569,360 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04150,203,461 - 150,215,641 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4484,098,346 - 84,110,524 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1484,384,810 - 84,396,991 (+)NCBI
Celera479,349,727 - 79,361,905 (+)NCBICelera
Cytogenetic Map4q24NCBI
AQP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2635,722,747 - 35,736,555 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1784,047,527 - 84,061,283 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0731,524,933 - 31,538,602 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1731,644,331 - 31,658,141 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl731,644,331 - 31,658,141 (+)Ensemblpanpan1.1panPan2
AQP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11443,592,266 - 43,603,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1443,578,721 - 43,605,720 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1443,024,519 - 43,036,159 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01443,532,873 - 43,544,517 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1443,532,714 - 43,546,331 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11443,648,522 - 43,660,154 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01443,325,031 - 43,336,701 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01443,686,308 - 43,697,947 (+)NCBIUU_Cfam_GSD_1.0
Aqp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511887,935,407 - 87,948,638 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364787,147,027 - 7,160,401 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364787,146,997 - 7,160,369 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1842,063,485 - 42,076,746 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11842,063,482 - 42,076,741 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AQP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12127,456,553 - 27,473,196 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2127,456,259 - 27,470,728 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604277,234,082 - 77,247,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624783164,609 - 177,766 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624783164,615 - 177,317 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000008825   ⟹   ENSCLAP00000008697
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541032,066,196 - 32,078,717 (+)Ensembl
RefSeq Acc Id: XM_005377508   ⟹   XP_005377565
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541032,066,196 - 32,078,661 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377565 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008697
  ENSCLAP00000008697.1
RefSeq Acc Id: XP_005377565   ⟸   XM_005377508
- UniProtKB: A0A8C2V119 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000008697   ⟸   ENSCLAT00000008825


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006088 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008825 ENTREZGENE
  ENSCLAT00000008825.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1080.10 UniProtKB/TrEMBL
InterPro Aquaporin-like UniProtKB/TrEMBL
  Aquaporin_1 UniProtKB/TrEMBL
  Aquaporin_transptr UniProtKB/TrEMBL
  MIP UniProtKB/TrEMBL
  MIP_CS UniProtKB/TrEMBL
NCBI Gene Aqp1 ENTREZGENE
PANTHER AQUAPORIN-1 UniProtKB/TrEMBL
  PTHR19139 UniProtKB/TrEMBL
Pfam MIP UniProtKB/TrEMBL
PRINTS AQUAPORIN1 UniProtKB/TrEMBL
  MINTRINSICP UniProtKB/TrEMBL
PROSITE MIP UniProtKB/TrEMBL
Superfamily-SCOP SSF81338 UniProtKB/TrEMBL
UniProt A0A8C2V119 ENTREZGENE, UniProtKB/TrEMBL