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Gene: Anos1 (anosmin 1) Chinchilla lanigera

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Symbol:

Anos1

Name:

anosmin 1

RGD ID:

8900487

Description:

ASSOCIATED WITH amenorrhea (ortholog); autistic disorder (ortholog); Delayed Puberty (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

anosmin-1; Kal1; Kallmann syndrome 1 sequence

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANOS1 (anosmin 1)	NCBI	Ortholog
Rattus norvegicus (Norway rat):	Wfdc17 (WAP four-disulfide core domain 17)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANOS1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANOS1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Anos1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANOS1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANOS1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Anos1 (anosmin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955499	6,486,682 - 6,687,484 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955499	6,486,287 - 6,686,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amenorrhea (ISO)

autistic disorder (ISO)

Delayed Puberty (ISO)

genetic disease (ISO)

hypogonadotropic hypogonadism (ISO)

hypogonadotropic hypogonadism 1 with or without anosmia (ISO)

hypogonadotropic hypogonadism 7 with or without anosmia (ISO)

Kallmann syndrome (ISO)

Klinefelter syndrome (ISO)

Martsolf syndrome 1 (ISO)

Neurodevelopmental Disorders (ISO)

Penis Agenesis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Anos1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955499	6,486,682 - 6,687,484 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955499	6,486,287 - 6,686,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

ANOS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	8,528,874 - 8,732,137 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	8,528,874 - 8,732,137 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	8,496,915 - 8,700,178 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	8,456,915 - 8,660,227 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	8,306,650 - 8,509,963	NCBI
Celera	X	12,674,609 - 12,877,889 (-)	NCBI		Celera
Cytogenetic Map	X	p22.31	NCBI
HuRef	X	6,324,418 - 6,527,699 (-)	NCBI		HuRef
CHM1_1	X	8,527,798 - 8,731,483 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	8,095,953 - 8,299,248 (-)	NCBI		T2T-CHM13v2.0

Wfdc17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	69,059,451 - 69,060,298 (+)	NCBI		GRCr8
mRatBN7.2	10	68,561,954 - 68,562,801 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	68,561,954 - 68,562,801 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0 Ensembl	10	70,999,780 - 71,000,627 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	71,184,154 - 71,185,001 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	71,861,031 - 71,861,878 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	67,496,704 - 67,498,775 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

ANOS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	10,211,785 - 10,411,468 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	10,215,454 - 10,415,134 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	1,035,112 - 1,235,112 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	8,396,742 - 8,594,270 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	8,396,290 - 8,598,406 (-)	Ensembl	panpan1.1		panPan2

ANOS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	5,413,958 - 5,601,663 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	5,415,575 - 5,762,656 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	5,367,752 - 5,554,283 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	5,352,344 - 5,540,023 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	5,352,509 - 5,708,860 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	5,349,001 - 5,536,136 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	5,380,797 - 5,570,226 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	5,373,980 - 5,560,664 (-)	NCBI		UU_Cfam_GSD_1.0

Anos1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404953	3,537,020 - 3,681,666 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936644	723,473 - 837,320 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936644	722,849 - 839,723 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANOS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	5,163,638 - 5,363,835 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa11.1	Y	3,807,032 - 4,014,112 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	5,365,573 - 5,562,552 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANOS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	7,012,410 - 7,223,223 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666056	8,646,875 - 8,851,048 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Anos1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624834	6,127,371 - 6,303,174 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624834	6,125,737 - 6,303,205 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013505608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01063547	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01063554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01028302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01025617	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000000222 ⟹ ENSCLAP00000000195

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955499	6,486,682 - 6,687,484 (-)	Ensembl

RefSeq Acc Id:

XM_013505608 ⟹ XP_013361062

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955499	6,486,287 - 6,686,739 (-)	NCBI

Sequence:

show sequence

GCTTCGGAGTGCGAGGGTTGAACTTTGCAGCCGAGTTGCGGCGGCCGCGAGGTGCCCGGCAGCG
CCGCCCCGGCTCGGAGCGGGGAGCCTCGGCCCGCGCGCGCCAGGCGCAGCCATGGACCCCGGGG
CGCCGCGCGCTGCCCTCGCCCTGCGCCTGTGCCTGTGGCTCTGCCTCTGGCTCTGGCTGGCGGC
CTCGGGGGGCTGCCTGGCGCCGAGCCCCGGCTTGGTGGCGGCGGCGCGGCGGCTGGACGAGTCG
CTGTCCGCTGGGAGCGTCCAGCGCGCGCGCTGCGCCTCCAGGTGCCTCAGCCTGCAGATCACGC
GCATCTCCGCCTTCTTCCACCACTTCCAGAACAATGGTTCCCTGGTTTGGTGCCAGAATCATAA
GCAGTGTTCTAAGTGCCTGGAGCCCTGCAAGGAACCAGGGGACTTGAGGAAACACCAGTGTCAA
AGCTTCTGTGAACCTCTGTTCCCCAAGAAGAACTATGAGTGCTTGACCAGCTGTGAGTTCCTGA
AGTACATCCTCCTGGTGAAACAAGGGGATTGCCCGGCTCCCGAGAAAGCCAGTGGCTTCGCTGC
CGCCTGCGTGGAGAGCTGTGAGGTTGACAATGAGTGCTCCGGGGTGAAAAAGTGTTGCTCTAAT
GGGTGTGGGTACACCTGCCAGGTGCCCAAGACTCTGTACAAAGGGGTCCCCTTGAAGCCCCGAA
AAGAGTTAAGGTTCACTGAGCTCAAGTCTGGGCAGCTGGAGATTAAGTGGTCCTCGAAGTTCAA
CATTTCCATTGAGCCAGTGATCTATGTGGTCCAAAGAAGGTGGAACTATGGGATCCATCCCAGT
GAAGACGACGCCACGCAGTGGCAGACAGTGGCCCAGACCACAGATGAGCAGGTGCAGCTGATGG
ACATAAGACCTAGCCGGTGGTACCAGTTCCGGGTGGCTGCTGTCAACGTGCATGGCACCCGAGG
CTTCACAGCACCCAGCAAACACTTCCGCTCTTCCAAAGATCCATCCGCACCACCAGCCCCAGCC
AATGTTCGGCTTGCCAACTCCACCATCAACAGTGATGGAAGTGTGACCGTGACTATTGTTTGGG
ACTTCCCCGAGGAGCCAGACAGCCCTGTGCACCACTACAAAGTATTCTGGAGCTGGCCGGTCAG
CAGCAAGTCCCTGGTCCCAACGAAAAAGAAGCGGAGAAAAACTACTGATGGGCTTCAGAACTCT
GTGACCCTGGATCGACTTCAGCCAGACTGCGACTACACAGTAGAACTACAGGCCATCGCCTACT
GGGGACAGACCCGCCTCAAGAGTGCCAAAGTATCACTGCACTTCACGTCCACACGCACTGGCAA
CAACAAAGATCAGCTGGGGAAAACTAGGAAAGGCATGGTCCCAGTGCAACCCCCTTTCCAAAGG
AGACGCCCCGCTCGCCCGCTAGAGATTGGAGCTCCGTTCTACCAAGACAACCAACTGCAAGTCA
AGGTCTACTGGAAAAAGACTGAAGATCCCAGTGTCAACCGATATCACGTGCAGTGGCTTCCGGA
AGTGTGCACTCACAACAGGACAGCCGGAGCAGAGATGTCCTCGGGCGTGACCCATGAAAATTAT
ATAATTCTTCAAGATCTGTCATTTTCCTGCAAATATAAGGTGACTGTCCAACCGATAAGCCCAA
AGGGTCTCTCAAAGGCAGAAGCCATTTTTTTTACTACCCCGCCATGCTCCACTTTGAAGGGAAA
AACCCAGAAGCACATCAGTTGCCCTGGGGATACAGGTCACGTCCTCTCCAAAGTGCTGGCCAAG
CCGGAGAACCTTTCTGCTGCATTCCTCGTGCAAGACATGAACATCACCGGCCACTTTTCTTGGA
AGATGACCAAAGCCAACCTCTATCAGCCCATGACCGGGTTCCAAGTGACTTGGGCTGAAGTCAC
CACAGAGAGCAGACAGAACAGCTTGCCCAACAGCATCATCTCCCAGTCGCAGATACTGCCCTCC
GATCACCACGTGCTCACCGTGCCCAACCTGAGGCCCTCCACCCTGTATCGCCTGGAAGTCCAAG
TGCTGACCACAGGCGGGGAGGGCCCGGCCACCATCAGGACGTTCCGGACCCCTGACCTCCCTCC
CTCTGCCATGCACCGACCCCATCCGAAACATCATCATACACATCATTACAAGCCATCTCCAGAA
AGATACTAAACCAGTCCCTGCCTGTCTCAACATTGTCCGGATGTGCACGCTTGTTGAACTTCAG
CTTCAAGACATGCGTCCCTCTACAACGGTAGGGACTTCTCAGACACTTAGCACAGTAAGCATTT
CTGCCAATCACAGATGCATCTGGGAATGTTTGATAAGTCACCACCCAGTACAGATGGACACCAG
TTCCCTAACAAAGAGGAGAAGAATGAAGAAGATGCTGTGAACTCTGAATTTCCTTTCTGTCTGT
GGTTTTGCTAATTTCTTTGGAATTACTGCAGAACTGAGATTTCCTTGAATTTGGAGCAGCAAGG
TCTTACAACAGAGTAGTGTAACAAATACAGAGTTTATATGCATACTAAATATACGTTTAATCAA
TAAAACATATTTTTATTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013361062	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000000195
	ENSCLAP00000000195.1

RefSeq Acc Id:

XP_013361062 ⟸ XM_013505608

- UniProtKB:

A0A8C2UII1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDPGAPRAALALRLCLWLCLWLWLAASGGCLAPSPGLVAAARRLDESLSAGSVQRARCASRCLS
LQITRISAFFHHFQNNGSLVWCQNHKQCSKCLEPCKEPGDLRKHQCQSFCEPLFPKKNYECLTS
CEFLKYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGYTCQVPKTLYKGVP
LKPRKELRFTELKSGQLEIKWSSKFNISIEPVIYVVQRRWNYGIHPSEDDATQWQTVAQTTDEQ
VQLMDIRPSRWYQFRVAAVNVHGTRGFTAPSKHFRSSKDPSAPPAPANVRLANSTINSDGSVTV
TIVWDFPEEPDSPVHHYKVFWSWPVSSKSLVPTKKKRRKTTDGLQNSVTLDRLQPDCDYTVELQ
AIAYWGQTRLKSAKVSLHFTSTRTGNNKDQLGKTRKGMVPVQPPFQRRRPARPLEIGAPFYQDN
QLQVKVYWKKTEDPSVNRYHVQWLPEVCTHNRTAGAEMSSGVTHENYIILQDLSFSCKYKVTVQ
PISPKGLSKAEAIFFTTPPCSTLKGKTQKHISCPGDTGHVLSKVLAKPENLSAAFLVQDMNITG
HFSWKMTKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHHVLTVPNLRPSTLYR
LEVQVLTTGGEGPATIRTFRTPDLPPSAMHRPHPKHHHTHHYKPSPERY

hide sequence

Ensembl Acc Id:

ENSCLAP00000000195 ⟸ ENSCLAT00000000222

Protein Domains

Fibronectin type-III WAP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000000196	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000000222	ENTREZGENE
	ENSCLAT00000000222.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	4.10.75.10	UniProtKB/TrEMBL
InterPro	Anosmin-1	UniProtKB/TrEMBL
	Anosmin-1_Cys_box	UniProtKB/TrEMBL
	Elafin-like_sf	UniProtKB/TrEMBL
	FN3_dom	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	WAP_dom	UniProtKB/TrEMBL
NCBI Gene	Kal1	ENTREZGENE
PANTHER	ANOSMIN-1	UniProtKB/TrEMBL
	PTHR14131	UniProtKB/TrEMBL
Pfam	Cys_box	UniProtKB/TrEMBL
	fn3	UniProtKB/TrEMBL
	WAP	UniProtKB/TrEMBL
PRINTS	4DISULPHCORE	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
	WAP	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
	WAP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49265	UniProtKB/TrEMBL
	SSF57256	UniProtKB/TrEMBL
UniProt	A0A8C2UII1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Anos1	anosmin 1	Kal1	Kallmann syndrome 1 sequence	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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