Il13 (interleukin 13) - Rat Genome Database

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Gene: Il13 (interleukin 13) Chinchilla lanigera
Analyze
Symbol: Il13
Name: interleukin 13
RGD ID: 8895145
Description: ENCODES a protein that exhibits cytokine activity (ortholog); interleukin-13 receptor binding (ortholog); INVOLVED IN cellular response to cytokine stimulus (ortholog); cellular response to mechanical stimulus (ortholog); inflammatory response (ortholog); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); alcoholic hepatitis (ortholog); allergic conjunctivitis (ortholog); FOUND IN cytoplasm (ortholog); external side of plasma membrane (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-13
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,046,406 - 4,049,795 (+)NCBIChiLan1.0ChiLan1.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
alcoholic hepatitis  (ISO)
allergic conjunctivitis  (ISO)
allergic disease  (ISO)
allergic rhinitis  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
autistic disorder  (ISO)
autoimmune hepatitis  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiolitis obliterans  (ISO)
chlamydia  (ISO)
Chronic Bronchitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
contact dermatitis  (ISO)
COVID-19  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
Delayed Hypersensitivity  (ISO)
dermatitis  (ISO)
diffuse scleroderma  (ISO)
drug allergy  (ISO)
Eczema  (ISO)
egg allergy  (ISO)
Endotoxemia  (ISO)
esophagitis  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
extrinsic allergic alveolitis  (ISO)
familial adenomatous polyposis 1  (ISO)
Fibrosis  (ISO)
food allergy  (ISO)
Fungal Lung Diseases  (ISO)
Graves' disease  (ISO)
hepatitis C  (ISO)
Hereditary Neoplastic Syndromes  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
Hyperplasia  (ISO)
Immediate Hypersensitivity  (ISO)
Inflammation  (ISO)
invasive ductal carcinoma  (ISO)
Kawasaki disease  (ISO)
lipoid nephrosis  (ISO)
localized scleroderma  (ISO)
lung disease  (ISO)
Lymphatic Metastasis  (ISO)
mastocytosis  (ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Metaplasia  (ISO)
middle cerebral artery infarction  (ISO)
milk allergy  (ISO)
multiple sclerosis  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
Nasal Polyps  (ISO)
Neurodevelopmental Disorders  (ISO)
occupational dermatitis  (ISO)
onchocerciasis  (ISO)
ovarian carcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatitis  (ISO)
peanut allergy  (ISO)
peptic esophagitis  (ISO)
Perennial Allergic Rhinitis  (ISO)
Picornaviridae Infections  (ISO)
Plasmodium falciparum malaria  (ISO)
pneumonia  (ISO)
Premature Birth  (ISO)
prostatic hypertrophy  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
purpura  (ISO)
Radiation Pneumonitis  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
Respiratory Sounds  (ISO)
respiratory syncytial virus infectious disease  (ISO)
Respiratory Tract Granuloma  (ISO)
Respiratory Tract Infections  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Schistosomiasis Mansoni  (ISO)
Sepsis  (ISO)
sinusitis  (ISO)
Sjogren's syndrome  (ISO)
systemic lupus erythematosus  (ISO)
systemic scleroderma  (ISO)
T-cell non-Hodgkin lymphoma  (ISO)
Transplant Rejection  (ISO)
uveitis  (ISO)
vitiligo  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to cytokine stimulus  (ISO)
cellular response to mechanical stimulus  (ISO)
inflammatory response  (ISO)
interleukin-13-mediated signaling pathway  (ISO)
macrophage activation  (ISO)
microglial cell activation  (ISO)
negative regulation of complement-dependent cytotoxicity  (ISO)
negative regulation of endothelial cell apoptotic process  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of NAD(P)H oxidase activity  (ISO)
negative regulation of transforming growth factor beta production  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of cold-induced thermogenesis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of immunoglobulin production  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of macrophage activation  (ISO)
positive regulation of mast cell degranulation  (ISO)
positive regulation of monoatomic ion transport  (ISO)
positive regulation of pancreatic stellate cell proliferation  (ISO)
positive regulation of protein secretion  (ISO)
positive regulation of release of sequestered calcium ion into cytosol  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
regulation of proton transport  (ISO)
response to ethanol  (ISO)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to nematode  (ISO)
response to nicotine  (ISO)
response to selenium ion  (ISO)
transforming growth factor beta receptor signaling pathway  (ISO)
transforming growth factor beta1 production  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Il13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,046,406 - 4,049,795 (+)NCBIChiLan1.0ChiLan1.0
IL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,656,522 - 132,661,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5132,656,263 - 132,661,110 (+)Ensemblhg38GRCh38
GRCh375131,992,214 - 131,996,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,021,764 - 132,024,700 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345132,021,763 - 132,024,700NCBI
Celera5128,123,995 - 128,126,931 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5127,186,169 - 127,189,105 (+)NCBIHuRef
CHM1_15131,427,162 - 131,430,098 (+)NCBICHM1_1
T2T-CHM13v2.05133,176,323 - 133,180,911 (+)NCBIT2T-CHM13v2.0
Il13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,522,150 - 53,525,529 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1153,522,151 - 53,525,529 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381153,631,323 - 53,634,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,631,324 - 53,634,702 (-)Ensemblmm10GRCm38
MGSCv371153,444,825 - 53,448,204 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361153,474,747 - 53,478,125 (-)NCBIMGSCv36mm8
Celera1158,210,849 - 58,214,228 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
Il13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81038,290,926 - 38,293,483 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1038,290,926 - 38,293,483 (-)EnsemblGRCr8
mRatBN7.21037,790,130 - 37,792,687 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1037,790,130 - 37,792,737 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1042,482,076 - 42,484,637 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01041,972,140 - 41,974,701 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01037,475,862 - 37,478,423 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01038,982,909 - 38,985,466 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,982,909 - 38,985,466 (-)Ensemblrn6Rnor6.0
Rnor_5.01038,764,639 - 38,767,196 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41039,093,512 - 39,096,069 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1037,134,342 - 37,136,897 (-)NCBICelera
RGSC_v3.11039,102,758 - 39,105,316 (-)NCBI
Cytogenetic Map10q22NCBI
IL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24127,968,733 - 127,973,681 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15126,108,155 - 126,113,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05128,073,863 - 128,078,453 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15134,235,788 - 134,240,548 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,235,788 - 134,240,548 (+)EnsemblpanPan2panpan1.1
IL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,957,870 - 20,961,391 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,958,464 - 20,961,388 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1119,759,917 - 19,762,847 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01121,744,389 - 21,747,318 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1121,744,389 - 21,747,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11120,462,871 - 20,465,798 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01120,310,464 - 20,313,371 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01120,952,917 - 20,955,847 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Il13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,527,018 - 115,529,671 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366472,530,491 - 2,532,373 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366472,529,933 - 2,532,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,972,623 - 134,975,093 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12134,972,099 - 134,976,672 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,441,025 - 140,444,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,475,762 - 35,479,419 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2335,476,490 - 35,478,869 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603442,463,847 - 42,466,277 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473339,428,095 - 39,429,843 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473339,427,189 - 39,430,019 (-)NCBIHetGla 1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005376104   ⟹   XP_005376161
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554084,046,406 - 4,049,795 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508342   ⟹   XP_013363796
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554084,046,406 - 4,048,173 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376161 (Get FASTA)   NCBI Sequence Viewer  
  XP_013363796 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005376161   ⟸   XM_005376104
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013363796   ⟸   XM_013508342
- Peptide Label: isoform X1
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene Il13 ENTREZGENE