Psmb7 (proteasome 20S subunit beta 7)

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Gene: Psmb7 (proteasome 20S subunit beta 7) Chinchilla lanigera

Analyze

Symbol:

Psmb7

Name:

proteasome 20S subunit beta 7

RGD ID:

8888424

Description:

ASSOCIATED WITH atrial fibrillation (ortholog); coat/hair pigmentation trait (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nuclear body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

proteasome (prosome, macropain) subunit, beta type, 7; proteasome subunit beta 7; proteasome subunit beta type-7

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	3,706,226 - 3,761,780 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	3,706,273 - 3,761,603 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Experimental Data Annotations Click to see Annotation Detail View

Vertebrate Trait

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
coat/hair pigmentation trait		ISO	PSMB7 (Canis lupus familiaris)	9068941	Coat colour and harlequin	OMIA	PMID:18513894 more ...

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

COVID-19 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

nuclear body (ISO)

nucleoplasm (ISO)

nucleus (ISO)

proteasome complex (ISO)

proteasome core complex (ISO)

Molecular Function

protein binding (ISO)

Experimental Data Annotations Click to see Annotation Detail View

Vertebrate Trait

coat/hair pigmentation trait (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Psmb7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	3,706,226 - 3,761,780 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	3,706,273 - 3,761,603 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSMB7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	124,353,465 - 124,415,442 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	124,353,465 - 124,415,444 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	127,115,744 - 127,177,721 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	126,155,565 - 126,217,542 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	124,195,298 - 124,257,275	NCBI
Celera	9	97,762,981 - 97,824,932 (-)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	96,700,699 - 96,790,409 (-)	NCBI		HuRef
CHM1_1	9	127,264,760 - 127,326,757 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	136,551,512 - 136,613,496 (-)	NCBI		T2T-CHM13v2.0

Psmb7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	38,478,058 - 38,533,964 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	38,478,048 - 38,534,099 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	38,588,046 - 38,643,952 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	38,588,036 - 38,644,087 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	38,443,566 - 38,499,426 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	38,410,055 - 38,465,915 (-)	NCBI		MGSCv36	mm8
Celera	2	40,309,890 - 40,367,955 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	24.42	NCBI

Psmb7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	22,357,777 - 22,417,748 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	22,354,698 - 22,417,937 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	25,825,962 - 25,885,969 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	34,410,959 - 34,470,964 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	32,223,450 - 32,283,379 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	22,890,072 - 22,951,718 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	22,871,105 - 22,952,063 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	28,115,649 - 28,176,245 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	18,384,197 - 18,451,208 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	18,280,569 - 18,347,580 (-)	NCBI
Celera	3	20,792,720 - 20,851,768 (-)	NCBI		Celera
Cytogenetic Map	3	q12	NCBI

PSMB7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	9	14,941,435 - 15,003,430 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	95,475,378 - 95,540,314 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	123,995,678 - 124,057,491 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	123,995,678 - 124,057,483 (-)	Ensembl	panpan1.1		panPan2

PSMB7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	58,529,646 - 58,593,016 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	58,529,723 - 58,593,016 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	57,726,668 - 57,789,932 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	59,449,060 - 59,512,699 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	59,449,136 - 59,512,699 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	58,207,216 - 58,270,483 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	58,523,766 - 58,587,042 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	58,614,281 - 58,677,679 (+)	NCBI		UU_Cfam_GSD_1.0

Psmb7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	192,866,027 - 192,921,441 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	12,631,612 - 12,689,936 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936487	12,634,561 - 12,689,914 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMB7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	265,172,237 - 265,235,387 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	265,172,257 - 265,235,389 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	298,943,412 - 299,006,545 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMB7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	13,722,982 - 13,790,427 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	13,728,724 - 13,793,290 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	2,286,572 - 2,349,790 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmb7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	10,678,673 - 10,738,009 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	10,678,800 - 10,738,008 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005382496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01019733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01010387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000019944 ⟹ ENSCLAP00000019751

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955419	3,706,226 - 3,761,780 (+)	Ensembl

RefSeq Acc Id:

XM_005382496 ⟹ XP_005382553

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955419	3,706,273 - 3,761,603 (+)	NCBI

Sequence:

show sequence

CTTTTTGTTGGCTTCACCCCCGGCCCGGAAATACTTTGTTGGGAAGATGGCGGCTGTGTCGGTC
TATGAGCACCCGGTTGGAGGTTTCTCGTTTGATAACTGCCGCAGGAATGCCGTCTTGGAAGCCG
ATTTTGCAAAGAAGGGGTTCAAGCTTCCTAAAGCCCGGAAAACTGGCACTACCATTGCGGGGTT
GGTCTATAAGGATGGCATAGTTCTTGGAGCAGATACACGAGCAACTGAAGGGATGGTTGTTGCT
GACAAGAACTGTTCAAAAATTCACTTCATAGCGCCTAATATTTACTGTTGCGGTGCTGGGACAG
CTGCAGACACAGACATGACAACGCAGCTCATTTCTTCCAACTTGGAGCTCCACTCCCTCACCAC
TGGGCGCCTTCCCAGAGTTGTGACGGCCAATCGGATGCTGAAGCAGATGCTTTTCAGGTATCAA
GGTTACATTGGTGCGGCCCTAGTTTTAGGGGGAATAGATGTTACCGGACCTCACCTCTACAGCA
TCTATCCTCATGGATCAACTGATAAGTTGCCTTACGTCACCATGGGGTCTGGCTCCTTGGCAGC
AATGGCTGTTTTTGAAGATAAATTTAGACCAGATATGGAGGAGGAGGAGGCCAAGAAGCTGGTG
AGTGAGGCCATTTCAGCTGGCATCTTCAATGACTTGGGGTCTGGGAGCAACATTGACCTGTGTG
TCATCAGCAAGAACAAGCTGGACTTTCTTCGCCCCTTCTCAGTGCCCAACAAGAAGGGGACCAG
GTTTGGTCGCTACAGATGTGAGAAGGGGACCACTGCAGTCCTGTCTGAAAAAGTCACTACTTTG
GAGATTGAGGTGCTGGAGGAGACTGTCCAAACGATGGACACTTCCTGAAGTGTCAGTGGGTGCT
GGGTGCTGAGTGCCGGGTGCTGCCCTGGAAGACTGGGGGCAGTGGAGCTCCATAGAAGATACTC
ATTTGGCTGTTTGCAGAACAGAGCTCAATAAAAATGAAAACCACAGTGCGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005382553	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000019751
	ENSCLAP00000019751.1

RefSeq Acc Id:

XP_005382553 ⟸ XM_005382496

- UniProtKB:

A0A8C2VZ21 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVSVYEHPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGLVYKDGIVLGADTRAT
EGMVVADKNCSKIHFIAPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQ
MLFRYQGYIGAALVLGGIDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEE
EAKKLVSEAISAGIFNDLGSGSNIDLCVISKNKLDFLRPFSVPNKKGTRFGRYRCEKGTTAVLS
EKVTTLEIEVLEETVQTMDTS

hide sequence

RefSeq Acc Id:

ENSCLAP00000019751 ⟸ ENSCLAT00000019944

Protein Domains

Proteasome beta subunit C-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013548	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000019944	ENTREZGENE
	ENSCLAT00000019944.1	UniProtKB/TrEMBL
Gene3D-CATH	3.60.20.10	UniProtKB/TrEMBL
InterPro	Ntn_hydrolases_N	UniProtKB/TrEMBL
	Pept_T1A_subB	UniProtKB/TrEMBL
	Proteasome_bsu_C	UniProtKB/TrEMBL
	Proteasome_bsu_CS	UniProtKB/TrEMBL
	Proteasome_sua/b	UniProtKB/TrEMBL
	Proteasome_suB-type	UniProtKB/TrEMBL
NCBI Gene	Psmb7	ENTREZGENE
PANTHER	METALLOPROTEASE TLDD	UniProtKB/TrEMBL
	PROTEASOME SUBUNIT BETA TYPE-7	UniProtKB/TrEMBL
Pfam	Pr_beta_C	UniProtKB/TrEMBL
	Proteasome	UniProtKB/TrEMBL
PRINTS	PROTEASOME	UniProtKB/TrEMBL
PROSITE	PROTEASOME_BETA_1	UniProtKB/TrEMBL
	PROTEASOME_BETA_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56235	UniProtKB/TrEMBL
UniProt	A0A8C2VZ21	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-09-03	Psmb7	proteasome 20S subunit beta 7	Psmb7	proteasome subunit beta 7	Symbol and/or name change	5135510	APPROVED
2015-08-25	Psmb7	proteasome subunit beta 7		proteasome (prosome, macropain) subunit, beta type, 7	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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