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Gene: Ffar3 (free fatty acid receptor 3) Chinchilla lanigera

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Symbol:

Ffar3

Name:

free fatty acid receptor 3

RGD ID:

8850923

Description:

ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); cellular response to fatty acid (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Brugada syndrome 5 (ortholog); dystonia (ortholog); essential hypertension (ortholog); FOUND IN membrane (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955468	4,627,686 - 4,634,499 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brugada syndrome 5 (ISO)

dystonia (ISO)

essential hypertension (ISO)

hereditary spastic paraplegia 75 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ISO)

cellular response to fatty acid (ISO)

G protein-coupled receptor signaling pathway (ISO)

glucose homeostasis (ISO)

mucosal immune response (ISO)

negative regulation of blood pressure (ISO)

negative regulation of insulin secretion (ISO)

neuronal action potential (ISO)

positive regulation of acute inflammatory response to non-antigenic stimulus (ISO)

positive regulation of chemokine production (ISO)

positive regulation of cytokine production involved in immune response (ISO)

positive regulation of neuronal action potential (ISO)

regulation of heart rate by chemical signal (ISO)

regulation of hormone biosynthetic process (ISO)

regulation of insulin receptor signaling pathway (ISO)

regulation of norepinephrine secretion (ISO)

regulation of peptide hormone secretion (ISO)

Cellular Component

membrane (ISO)

plasma membrane (ISO)

Molecular Function

G protein-coupled receptor activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ffar3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955468	4,627,686 - 4,634,499 (+)	NCBI	ChiLan1.0	ChiLan1.0

FFAR3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	35,358,151 - 35,360,489 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	35,358,460 - 35,360,489 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	35,849,362 - 35,851,391 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	40,541,342 - 40,543,231 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	40,541,341 - 40,543,227	NCBI
Celera	19	32,562,940 - 32,564,843 (+)	NCBI		Celera
Cytogenetic Map	19	q13.12	NCBI
HuRef	19	32,357,984 - 32,370,911 (+)	NCBI		HuRef
CHM1_1	19	35,851,096 - 35,852,999 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	37,902,884 - 37,905,223 (+)	NCBI		T2T-CHM13v2.0

Ffar3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	30,553,755 - 30,555,603 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	30,553,755 - 30,555,603 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	30,854,330 - 30,856,178 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	30,854,330 - 30,856,178 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	31,639,349 - 31,641,197 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	30,563,090 - 30,564,938 (-)	NCBI		MGSCv36	mm8
Celera	7	25,437,774 - 25,439,622 (-)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI
cM Map	7	19.25	NCBI

Ffar3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	95,232,804 - 95,234,144 (-)	NCBI		GRCr8
mRatBN7.2	1	86,105,388 - 86,106,728 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	86,104,920 - 86,106,849 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	91,520,010 - 91,521,350 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	99,986,179 - 99,987,519 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	93,278,309 - 93,279,649 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	89,302,035 - 89,304,064 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	89,302,039 - 89,303,968 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	90,457,561 - 90,459,558 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	85,911,239 - 85,912,579 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	85,961,180 - 85,991,480 (-)	NCBI
Celera	1	80,473,836 - 80,475,176 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

FFAR3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	41,371,323 - 41,373,439 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	43,354,671 - 43,356,787 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	32,305,112 - 32,307,223 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	41,041,808 - 41,055,938 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	41,054,341 - 41,055,381 (+)	Ensembl	panpan1.1		panPan2

FFAR3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	117,251,604 - 117,257,048 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	116,654,563 - 116,656,672 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	117,851,342 - 117,853,431 (-)	NCBI		ROS_Cfam_1.0
UNSW_CanFamBas_1.0	1	117,040,133 - 117,042,241 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	118,095,603 - 118,097,714 (-)	NCBI		UU_Cfam_GSD_1.0

Ffar3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	10,693,229 - 10,696,348 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936570	949,575 - 951,442 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FFAR3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	44,844,149 - 44,845,172 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	40,332,798 - 40,339,457 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FFAR3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	30,296,020 - 30,306,671 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666073	8,085,695 - 8,087,971 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ffar3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624794	8,200,101 - 8,202,145 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005400051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01051918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01051919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005400051 ⟹ XP_005400108

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955468	4,627,686 - 4,634,499 (+)	NCBI

Sequence:

show sequence

CCCGGTTGCTTGTCCAGGCCCCGGCCAGAACGGCAGGACAGCCTCGCCCAGAGCCACTCGTGGG
AAGAGCTGAGCCTGGAGAGGCAGCATCTCGGTCCAGAGAGAGAGCGAAGGCCAGGAGCCGGGCG
CAGGCGCAGGCGAGCTGGCCCTGATGATGGAGATAAACCCAGACCGGTCCTTCTTCCCCGGAAA
CCACTGGCTCTACTTCTCCGTGTACCTATTCGCCTTCCTGGTGGGGCTGCCCCTGAACCTGATG
GCCCTGGTGATCTTCGTGGGTAAACTTCGGCGCCGCCCAGTGGCTGTGGATGTGCTCCTGCTCA
ACCTGACCCTCTCGGACCTGCTGCTGCTGCTCTTCCTGCCCTTCCGCATGGTGGAGGCGGCCAG
CGGGATGCGCTGGCCCCTGCCCTTCATCCTCTGCCCACTCTCCGGCTTCCTCTTCTTCACCACC
ATCTATCTCACCTCCCTCTTCCTGGCGGCTGTGAGCGTCGAGCGCCTCCTGAGCGTGGCCTACC
CTCTGTGGTACAAGACTCGGCCGAGGCTGGCTCAGGCGGGGCTGGTCAGTGGCATCTGCTGGTT
CCTGGCGGGTGCTCACTGCAGTGTGGTCTATGTCACTGAATTCTGGGGGAACTTCACCCAGAGC
CAGGGCACTAATGGGACCTGCTACCTGGAATTCAGAAAGGACCAGCTGGCCATTCTGCTGCCCG
TCCGGCTGGAGATGGGTGTGGTCCTTTTCGGGGTGCCTCTGCTCATCACCAGCTACTGCTACAG
CCGCCTGGTATGGATCCTCGGCCGAAGCTCCAGCAGACGCCGGCGCAGGAGGGTGGCGGGGCTG
GTGGTGGCCTCACTGCTCAACTTCCTTGTCTGCTTTGGGCCCTACAACGTGTCACACTTGGTTG
GCTACATTCAGGGCAAGAGCCCGACGTGGAGGAGTTACGTGCTGCTCCTCAGCACTCTGAACTC
CTGTGTCGACCCCCTTGTCTACTACTTCTCATCATCAAGGTTCCAAGTGGACTTCCACGAGCTG
CTGGGGAGGCTGACTGGAGGCTGGGGCCCTGGCAGCCAGGAGGTTAGTGTGGAACTGAAGGTCA
AGGACGGAGGAGAGTGGCTGGCGCAGGACTGTCCAACCTAGAAATCAGGGGTAGACTCGAGGAA
GGCTTCAGAATAGTTGGCCTTATGGCCTGTGCTGAAATTGAGCTCCTCTGGGGCAGGAAGGCAG
AGCAAGTGTATGTACTCACGGCAGAGCTTAACTCAAGCCAGGCAGGACCTTGCAGCAGCAGGCT
GGGTCCCGGTGCAGCTCAAGGACAGAGCAGCCACCTGGACTTCCTAGGGATGTGCCGAACTCTT
GAGATCCCACCTCCCTTCCCTTCCTCCCACTCTTGAGAGGCTGCTGTGGAGGAAAACGAGCCAG
TGCTCGGACAAAGAGCTGTCCGTGACTCTGGGCAGGAAAGGGTAGGAATCCAGCCTTCAGAGCT
ACTCCTGTCCAGATGTCAGGGGCAGGGGACACAGGGCTCCAGGGAAGAGTGAAACCTGCCCTCC
CTCGGAGGGGCTTTTCCAGAAAGTTTCTATTGCTCAACCAACTCAGATCTTTAAGGATGCTTAT
GAACCATGA

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Protein Sequences


Protein RefSeqs	XP_005400108	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000020851
	ENSCLAP00000020851.1

RefSeq Acc Id:

XP_005400108 ⟸ XM_005400051

- UniProtKB:

A0A8C2VUQ8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MMEINPDRSFFPGNHWLYFSVYLFAFLVGLPLNLMALVIFVGKLRRRPVAVDVLLLNLTLSDLL
LLLFLPFRMVEAASGMRWPLPFILCPLSGFLFFTTIYLTSLFLAAVSVERLLSVAYPLWYKTRP
RLAQAGLVSGICWFLAGAHCSVVYVTEFWGNFTQSQGTNGTCYLEFRKDQLAILLPVRLEMGVV
LFGVPLLITSYCYSRLVWILGRSSSRRRRRRVAGLVVASLLNFLVCFGPYNVSHLVGYIQGKSP
TWRSYVLLLSTLNSCVDPLVYYFSSSRFQVDFHELLGRLTGGWGPGSQEVSVELKVKDGGEWLA
QDCPT

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Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014285	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021051	ENTREZGENE
	ENSCLAT00000021051.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	GPR40-rel_orph	UniProtKB/TrEMBL
NCBI Gene	Ffar3	ENTREZGENE
PANTHER	FREE FATTY ACID RECEPTOR 2-RELATED	UniProtKB/TrEMBL
	FREE FATTY ACID RECEPTOR 3-RELATED	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	GPR40FAMILY	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8C2VUQ8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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