Nelfcd (negative elongation factor complex member C/D) - Rat Genome Database

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Gene: Nelfcd (negative elongation factor complex member C/D) Chinchilla lanigera
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Symbol: Nelfcd
Name: negative elongation factor complex member C/D
RGD ID: 8818196
Description: INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH amyotrophic lateral sclerosis type 8 (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: negative elongation factor C/D
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955445597,826 - 610,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955445597,826 - 610,134 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
NELF complex  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nelfcd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955445597,826 - 610,134 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955445597,826 - 610,134 (-)NCBIChiLan1.0ChiLan1.0
NELFCD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382058,981,256 - 58,995,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2058,981,208 - 58,995,133 (+)EnsemblGRCh38hg38GRCh38
GRCh372057,556,311 - 57,570,168 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362056,989,706 - 57,003,583 (+)NCBINCBI36Build 36hg18NCBI36
Build 342056,989,705 - 57,003,581NCBI
Celera2054,296,740 - 54,310,603 (+)NCBICelera
Cytogenetic Map20q13.32NCBI
HuRef2054,343,186 - 54,357,094 (+)NCBIHuRef
CHM1_12057,457,652 - 57,471,577 (+)NCBICHM1_1
T2T-CHM13v2.02060,764,380 - 60,778,214 (+)NCBIT2T-CHM13v2.0
Nelfcd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392174,257,623 - 174,269,298 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2174,257,597 - 174,269,295 (+)EnsemblGRCm39 Ensembl
GRCm382174,415,804 - 174,427,505 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2174,415,804 - 174,427,502 (+)EnsemblGRCm38mm10GRCm38
MGSCv372174,241,305 - 174,253,003 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362174,058,743 - 174,070,436 (+)NCBIMGSCv36mm8
Celera2180,375,996 - 180,388,332 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map297.93NCBI
Nelfcd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83183,631,968 - 183,643,088 (+)NCBIGRCr8
mRatBN7.23163,213,765 - 163,224,886 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3163,213,762 - 163,224,884 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3167,012,506 - 167,023,627 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03175,508,965 - 175,520,084 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03173,253,352 - 173,264,473 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03172,510,840 - 172,527,118 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3172,510,874 - 172,526,740 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03178,565,103 - 178,574,630 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3162,387,255 - 162,398,373 (+)NCBICelera
Cytogenetic Map3q43NCBI
NELFCD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22164,744,607 - 64,758,512 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12064,737,729 - 64,751,634 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02055,332,309 - 55,346,167 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12056,697,394 - 56,706,458 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2056,693,685 - 56,706,458 (+)Ensemblpanpan1.1panPan2
NELFCD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12443,685,356 - 43,743,239 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2443,734,236 - 43,743,233 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2442,976,753 - 42,989,365 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02444,596,768 - 44,609,381 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2444,596,635 - 44,609,369 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12443,700,324 - 43,712,935 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02443,819,006 - 43,831,619 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02444,478,807 - 44,491,418 (+)NCBIUU_Cfam_GSD_1.0
Nelfcd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640181,824,278 - 181,832,136 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365301,474,136 - 1,481,567 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365301,474,097 - 1,481,943 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NELFCD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1759,129,076 - 59,141,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11759,129,055 - 59,141,499 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21766,499,448 - 66,511,907 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NELFCD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.125,146,137 - 5,159,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl25,146,575 - 5,159,883 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605053,197,345 - 53,211,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nelfcd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474125,267,359 - 25,280,844 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474125,267,334 - 25,280,844 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000008545   ⟹   ENSCLAP00000008418
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955445597,826 - 610,134 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000008546   ⟹   ENSCLAP00000008419
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955445598,286 - 610,095 (-)Ensembl
RefSeq Acc Id: XM_013518266   ⟹   XP_013373720
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955445597,826 - 610,134 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518267   ⟹   XP_013373721
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955445597,826 - 610,134 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013373720 (Get FASTA)   NCBI Sequence Viewer  
  XP_013373721 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000008418
  ENSCLAP00000008418.1
  ENSCLAP00000008419.1
RefSeq Acc Id: XP_013373721   ⟸   XM_013518267
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V6C4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013373720   ⟸   XM_013518266
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V6C4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000008418   ⟸   ENSCLAT00000008545
Ensembl Acc Id: ENSCLAP00000008419   ⟸   ENSCLAT00000008546


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008545 ENTREZGENE
  ENSCLAT00000008545.1 UniProtKB/TrEMBL
  ENSCLAT00000008546.1 UniProtKB/TrEMBL
InterPro TH1 UniProtKB/TrEMBL
NCBI Gene LOC102019750 ENTREZGENE
PANTHER NEGATIVE ELONGATION FACTOR C/D UniProtKB/TrEMBL
  PTHR12144 UniProtKB/TrEMBL
Pfam TH1 UniProtKB/TrEMBL
UniProt A0A8C2V2L7_CHILA UniProtKB/TrEMBL
  A0A8C2V6C4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Nelfcd  negative elongation factor complex member C/D  LOC102019750  negative elongation factor D-like  Symbol and/or name change 5135510 APPROVED