Hsp90ab1 (heat shock protein 90 alpha family class B member 1) - Rat Genome Database

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Gene: Hsp90ab1 (heat shock protein 90 alpha family class B member 1) Chinchilla lanigera
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Symbol: Hsp90ab1
Name: heat shock protein 90 alpha family class B member 1
RGD ID: 8813783
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATP-dependent protein binding (ortholog); CTP binding (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to interleukin-4 (ortholog); cellular response to organic cyclic compound (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; cortisol signaling pathway; ASSOCIATED WITH Female Infertility (ortholog); human immunodeficiency virus infectious disease (ortholog); intrahepatic cholangiocarcinoma (ortholog); FOUND IN apical plasma membrane (ortholog); aryl hydrocarbon receptor complex (ortholog); axonal growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein HSP 90-beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,873,908 - 9,878,459 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,872,649 - 9,878,459 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hsp90ab1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,873,908 - 9,878,459 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,872,649 - 9,878,459 (+)NCBIChiLan1.0ChiLan1.0
HSP90AB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,246,194 - 44,253,883 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,246,166 - 44,253,888 (+)EnsemblGRCh38hg38GRCh38
GRCh37644,213,931 - 44,221,620 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,322,827 - 44,329,592 (+)NCBINCBI36Build 36hg18NCBI36
Build 34644,322,826 - 44,329,592NCBI
Celera645,767,994 - 45,774,759 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,935,917 - 43,943,640 (+)NCBIHuRef
CHM1_1644,217,626 - 44,225,330 (+)NCBICHM1_1
T2T-CHM13v2.0644,080,360 - 44,088,031 (+)NCBIT2T-CHM13v2.0
Hsp90ab1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,878,704 - 45,884,187 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,878,701 - 45,884,197 (-)EnsemblGRCm39 Ensembl
GRCm381745,567,778 - 45,573,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,567,775 - 45,573,271 (-)EnsemblGRCm38mm10GRCm38
MGSCv371745,704,727 - 45,710,210 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,031,359 - 45,036,842 (-)NCBIMGSCv36mm8
Celera1749,000,428 - 49,005,921 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.59NCBI
Hsp90ab1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,930,249 - 22,935,929 (+)NCBIGRCr8
mRatBN7.2915,432,986 - 15,438,358 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,433,691 - 15,438,488 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,019,488 - 24,024,885 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,082,165 - 29,087,562 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,382,927 - 27,388,324 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,817,791 - 17,823,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,817,721 - 17,823,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,706,512 - 16,711,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,033,496 - 11,038,868 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,030,786 - 11,036,319 (+)NCBI
Celera913,176,225 - 13,181,597 (+)NCBICelera
Cytogenetic Map9q12NCBI
HSP90AB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,750,514 - 58,757,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,620,583 - 54,627,983 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,842,796 - 43,849,637 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,126,060 - 45,132,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,125,773 - 45,133,872 (+)Ensemblpanpan1.1panPan2
HSP90AB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,658,415 - 12,664,945 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,660,008 - 12,664,940 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,682,075 - 12,689,685 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,139,324 - 13,147,144 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,140,459 - 13,147,650 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,665,005 - 12,672,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,752,685 - 12,760,264 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,846,448 - 12,854,258 (+)NCBIUU_Cfam_GSD_1.0
Hsp90ab1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,123,181 - 48,129,743 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,830,459 - 15,835,535 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,830,459 - 15,836,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90AB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,244,458 - 39,250,481 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,237,299 - 39,250,479 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,106,779 - 45,119,936 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90AB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,914,261 - 27,921,666 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,911,013 - 27,921,251 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,300,580 - 44,307,963 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsp90ab1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,609,920 - 15,614,263 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,609,932 - 15,615,580 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000023154   ⟹   ENSCLAP00000022939
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554379,873,908 - 9,878,459 (+)Ensembl
RefSeq Acc Id: XM_005389809   ⟹   XP_005389866
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554379,872,649 - 9,878,192 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013516839   ⟹   XP_013372293
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554379,873,908 - 9,878,459 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005389866 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372293 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022939
  ENSCLAP00000022939.1
RefSeq Acc Id: XP_005389866   ⟸   XM_005389809
- UniProtKB: A0A8C2YTV6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013372293   ⟸   XM_013516839
- UniProtKB: A0A8C2YTV6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000022939   ⟸   ENSCLAT00000023154
Protein Domains
Histidine kinase/HSP90-like ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015740 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023154 ENTREZGENE
  ENSCLAT00000023154.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.790 UniProtKB/TrEMBL
  3.30.230.80 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
  3.40.50.11260 UniProtKB/TrEMBL
InterPro HATPase_C UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/TrEMBL
  Heat_shock_protein_90_CS UniProtKB/TrEMBL
  HSP90_C UniProtKB/TrEMBL
  Hsp90_fam UniProtKB/TrEMBL
  Hsp90_N UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
NCBI Gene Hsp90ab1 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN HSP 90-BETA UniProtKB/TrEMBL
  PTHR11528 UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/TrEMBL
  HSP90 UniProtKB/TrEMBL
PIRSF Hsp90 UniProtKB/TrEMBL
PRINTS HEATSHOCK90 UniProtKB/TrEMBL
PROSITE HSP90 UniProtKB/TrEMBL
SMART HATPase_c UniProtKB/TrEMBL
Superfamily-SCOP SSF110942 UniProtKB/TrEMBL
  SSF54211 UniProtKB/TrEMBL
  SSF55874 UniProtKB/TrEMBL
UniProt A0A8C2YTV6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Hsp90ab1  heat shock protein 90 alpha family class B member 1    heat shock protein 90kDa alpha (cytosolic), class B member 1  Symbol and/or name change 5135510 APPROVED