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Gene: Dnajb11 (DnaJ heat shock protein family (Hsp40) member B11) Chinchilla lanigera

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Symbol:

Dnajb11

Name:

DnaJ heat shock protein family (Hsp40) member B11

RGD ID:

8735442

Description:

ENCODES a protein that exhibits misfolded protein binding (ortholog); signaling receptor binding (ortholog); unfolded protein binding (ortholog); INVOLVED IN mRNA modification (ortholog); negative regulation of neurogenesis (ortholog); positive regulation of ATP-dependent activity (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); autosomal dominant polycystic kidney disease (ortholog); cystic kidney disease (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum chaperone complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

DnaJ (Hsp40) homolog, subfamily B, member 11; dnaJ homolog subfamily B member 11

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	21,097,941 - 21,112,792 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	21,097,292 - 21,113,053 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3MC syndrome 1 (ISO)

autosomal dominant polycystic kidney disease (ISO)

cystic kidney disease (ISO)

genetic disease (ISO)

oligohydramnios (ISO)

polycystic kidney disease (ISO)

polycystic kidney disease 6 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA modification (ISO)

negative regulation of neurogenesis (ISO)

positive regulation of ATP-dependent activity (ISO)

protein maturation (ISO)

Cellular Component

cytoplasm (ISO)

endoplasmic reticulum (ISO)

endoplasmic reticulum chaperone complex (ISO)

extracellular space (ISO)

nucleus (ISO)

protein folding chaperone complex (ISO)

Molecular Function

misfolded protein binding (ISO)

protein binding (ISO)

signaling receptor binding (ISO)

unfolded protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

codeine and morphine pharmacodynamics pathway (ISO)

codeine and morphine pharmacokinetics pathway (ISO)

etoposide pharmacodynamics pathway (ISO)

etoposide pharmacokinetics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacokinetics pathway (ISO)

irinotecan pharmacodynamics pathway (ISO)

irinotecan pharmacokinetics pathway (ISO)

paracetamol pharmacokinetics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

retinol metabolic pathway (ISO)

sorafenib pharmacokinetics pathway (ISO)

vitamin A deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Dnajb11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	21,097,941 - 21,112,792 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	21,097,292 - 21,113,053 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAJB11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	186,570,720 - 186,585,793 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	186,567,403 - 186,585,800 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	186,288,509 - 186,303,582 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	187,771,161 - 187,786,283 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	187,771,168 - 187,786,290	NCBI
Celera	3	184,724,844 - 184,739,974 (+)	NCBI		Celera
Cytogenetic Map	3	q27.3	NCBI
HuRef	3	183,697,521 - 183,712,654 (+)	NCBI		HuRef
CHM1_1	3	186,252,405 - 186,267,524 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	189,386,442 - 189,401,527 (+)	NCBI		T2T-CHM13v2.0

Dnajb11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	22,676,595 - 22,698,384 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	22,676,595 - 22,698,384 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	22,857,845 - 22,879,634 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	22,857,845 - 22,879,634 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	22,857,939 - 22,879,707 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	22,773,252 - 22,787,713 (+)	NCBI		MGSCv36	mm8
Celera	16	23,418,190 - 23,439,958 (+)	NCBI		Celera
Cytogenetic Map	16	B1	NCBI
cM Map	16	13.71	NCBI

Dnajb11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	91,656,334 - 91,672,800 (-)	NCBI		GRCr8
mRatBN7.2	11	78,151,750 - 78,168,259 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	78,150,429 - 78,180,407 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	86,902,218 - 86,918,676 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	79,554,020 - 79,570,432 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	78,616,525 - 78,632,987 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	81,741,342 - 81,757,806 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	81,741,297 - 81,757,813 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	84,829,171 - 84,845,635 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	80,360,406 - 80,376,870 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	80,417,995 - 80,434,459 (-)	NCBI
Celera	11	77,022,552 - 77,038,995 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

DNAJB11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	184,442,764 - 184,458,388 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	184,447,899 - 184,463,103 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	183,601,386 - 183,617,013 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	192,069,326 - 192,084,943 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	192,069,326 - 192,084,943 (+)	Ensembl	panpan1.1		panPan2

DNAJB11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	19,182,850 - 19,202,229 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	19,182,400 - 19,202,238 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	23,268,157 - 23,287,641 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	19,093,585 - 19,113,054 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	19,096,089 - 19,113,065 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	19,119,798 - 19,139,251 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	19,125,752 - 19,145,218 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	19,354,386 - 19,373,856 (+)	NCBI		UU_Cfam_GSD_1.0

Dnajb11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	117,268,412 - 117,282,779 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936578	3,360,259 - 3,374,612 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936578	3,360,259 - 3,374,634 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJB11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	124,390,970 - 124,413,200 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	124,387,921 - 124,409,967 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	133,779,407 - 133,801,470 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJB11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	2,841,377 - 2,858,192 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	2,841,255 - 2,858,202 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	11,589,603 - 11,606,489 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajb11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	70,170,003 - 70,186,031 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	70,173,024 - 70,185,492 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013513338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01021123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01021124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01021125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCC01049191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01118251	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000021562 ⟹ ENSCLAP00000021359

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955420	21,097,941 - 21,112,792 (-)	Ensembl

RefSeq Acc Id:

XM_013513338 ⟹ XP_013368792

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955420	21,097,292 - 21,113,053 (-)	NCBI

Sequence:

show sequence

CGACGTGCCGGCCGCGTGTGATGTCCCGGGCGGCGATTGGCCGCTCGCCTGCCGGGGGCTCCTT
TCACCGGGACTCGGGACTCCCGGGAAGTGGGCCGGCAGAGGAGGGGGGCAAGCTAGCTCTCTGT
GCGGACCTAGTAGAAGACCCCCCCCCGCCCCCGGTGTGAGGCCGCCTCACCTGGCCAGCAGGGC
TGGCCAGCCTACGCGGCGGCGGAGGAGGCCGTGAGGAGTACGCGGGACGGGGGCCGGCGCGGAG
GGACCATGGCCCCGCAGAACCTGGGCACCTTCTGCCTGTTGCTGTTGTACCTCATCGGGGCCGT
GATCGCCGGGCGAGATTTCTATAAGATCTTGGGAGTTCCGCGCAGTGCCTCTATAAAGGACATT
AAAAAGGCCTACAGGAAACTAGCCCTGCAGCTCCATCCTGACAGGAATCCTGATGACCCCCAAG
CCCAGGAGAAATTCCAGGATCTGGGTGCTGCTTATGAGGTGCTGTCAGATAATGAGAAACGGAA
ACAGTATGATACTTACGGTGAGGAAGGATTAAAAGACGGTCATCAGAGCTCCCATGGAGACATT
TTTTCACACTTCTTTGGAGATTTTGGTTTCATGTTTGGAGGAACCCCTCGTCAGCAAGACAGAA
ACATTCCAAGAGGAAGTGATATTATTGTAGATCTAGAAGTCACTTTGGAAGAAGTGTATGCAGG
AAACTTTGTGGAAGTAAGTTCAAACAATATAACTGCTACTATCGACTTTCAGAACTTCTGTCGG
CAAGAGATGCGGACCACACAGCTGGGCCCTGGGCGCTTCCAGATGACGCAGGAAGTGGTCTGCG
ACGAGTGCCCTAACGTCAAACTAGTGAATGAAGAACGAACACTGGAGGTAGAAATAGAACCCGG
CGTGAGAGATGGCATGGAGTACCCCTTCATCGGAGAAGGTGAACCTCACGTGGATGGGGAGCCT
GGAGACTTACGGTTCCGAATCAAAGTTGTCAAGCACCGAATATTTGAAAGAAGAGGAGATGATC
TGTACACAAATGTGACAATCTCACTAGTTGAGGCTCTGGTCGGCTTTGAGATGGATATTACTCA
CTTGGATGGTCACAAGGTGCATATTTCCCGGGACAAGATCACCAGGCCAGGAGCCAAGCTATGG
AAGAAAGGGGAAGGGCTCCCCAACTTTGACAATAACAACATCAAGGGCTCTTTGATAATCACTT
TTGATGTGGATTTTCCAAAAGAACAGTTAACAGAGGAAGCAAGAGAAGGTATCAAACAGCTTCT
GAAACAAGGATCAGTGCAGAAGGTATACAATGGACTGCAAGGATATTAAGAGTGAATAAAATTG
GACTTTGTTGAAAATAAGTGAATCGGCGATATTTATTATCTGCAGGGTTTTTGTGTGTGGTTTT
GTTTTTATTTTCATATGCAAGTTTTAATTTTTTTCCTGATGGTCATCATGATGTGAATAAGAGG
GCTTAAGAATTTTTCCATTTGCATTCAGACAAGAATGACCAGGAAAATGGTTCACTAATACCTC
TCCCTTTGGGGATATATTGTCTGGTGCTGCCACCTGAATTTCAAGAATTAAAGCTGCAAGAGGA
CTGTTAAGAACAAAAGAAACAAGGCGAAGGGTTGGAGCTAACTGTTAGTTACTCCATTCAAAAT
GCCAACTGGAGAAGTCTGTTTTTAAATACATCTTGTTATTTTTTCCTGACTCCTGTTTCTTTTC
TCCTGTGAGCTATTCGGGTTGTCCTCTCTCCCCACCATGCAAGATGGACATACAAGCATGCAAA
AGAATGCTGAGATGCAGTCCTTGCTCCACGAAACACACATGGCATCTTCTAGCAGAGAGCTTGA
AGAAAACCAGTAGATTAGAGAACGGGCTACAAAAATCAAGATTATACAAAGATCTAACTGTCCT
TGAGAAAAAGTATATTTTCTCTCATTTGGGAACAATAAAATCTGATATGGATACTTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013368792	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000021359
	ENSCLAP00000021359.1

RefSeq Acc Id:

XP_013368792 ⟸ XM_013513338

- Sequence:

show sequence

MAPQNLGTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQ
EKFQDLGAAYEVLSDNEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQDRNI
PRGSDIIVDLEVTLEEVYAGNFVEVSSNNITATIDFQNFCRQEMRTTQLGPGRFQMTQEVVCDE
CPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHRIFERRGDDLY
TNVTISLVEALVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFD
VDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY

hide sequence

Ensembl Acc Id:

ENSCLAP00000021359 ⟸ ENSCLAT00000021562

Protein Domains

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000014627	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000021562	ENTREZGENE
	ENSCLAT00000021562.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
	Urease metallochaperone UreE, N-terminal domain	UniProtKB/TrEMBL
InterPro	DnaJ-B11-like	UniProtKB/TrEMBL
	DnaJ_C	UniProtKB/TrEMBL
	DnaJ_domain	UniProtKB/TrEMBL
	DnaJ_domain_CS	UniProtKB/TrEMBL
	HSP40/DnaJ_pept-bd	UniProtKB/TrEMBL
	J_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Dnajb11	ENTREZGENE
PANTHER	DNAJ HOMOLOG SUBFAMILY B MEMBER 11	UniProtKB/TrEMBL
	DNAJ HOMOLOG SUBFAMILY B MEMBER 11	UniProtKB/TrEMBL
Pfam	DnaJ	UniProtKB/TrEMBL
	DnaJ_C	UniProtKB/TrEMBL
PRINTS	JDOMAIN	UniProtKB/TrEMBL
PROSITE	DNAJ_1	UniProtKB/TrEMBL
	DNAJ_2	UniProtKB/TrEMBL
SMART	DnaJ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46565	UniProtKB/TrEMBL
	SSF49493	UniProtKB/TrEMBL
UniProt	A0A8C2W2T0_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Dnajb11	DnaJ heat shock protein family (Hsp40) member B11		DnaJ (Hsp40) homolog, subfamily B, member 11	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB