Edn2 (endothelin 2) - Rat Genome Database

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Gene: Edn2 (endothelin 2) Mus musculus
Analyze
Symbol: Edn2
Name: endothelin 2
RGD ID: 737549
MGI Page MGI
Description: Predicted to enable endothelin B receptor binding activity and hormone activity. Involved in several processes, including axon extension; positive regulation of prostaglandin-endoperoxide synthase activity; and prostaglandin biosynthetic process. Acts upstream of or within several processes, including energy homeostasis; lung alveolus development; and positive regulation of smooth muscle contraction. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and skeleton. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human EDN2 (endothelin 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: endothelin-2; ET-2; PPET2; preproendothelin-2; V; vasoactive intestinal contractor peptide; VIC
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,018,403 - 120,024,557 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,018,403 - 120,024,557 (+)EnsemblGRCm39 Ensembl
GRCm384120,161,206 - 120,167,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,161,206 - 120,167,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv374119,834,029 - 119,839,965 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364119,659,068 - 119,664,996 (+)NCBIMGSCv36mm8
Celera4118,876,990 - 118,882,911 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map455.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
aspartame  (ISO)
Azoxymethane  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
BQ 123  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (EXP)
calcium(0)  (EXP)
cisplatin  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
corticosterone  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (EXP)
ethanol  (EXP)
fenvalerate  (ISO)
folic acid  (ISO)
gemcitabine  (ISO)
genistein  (EXP,ISO)
hydroquinone  (ISO)
ibuprofen  (EXP)
lead diacetate  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
naphthalene  (EXP)
nickel dichloride  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (EXP)
pirinixic acid  (EXP)
propanal  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (EXP,ISO)
tamibarotene  (ISO)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
tricetin  (ISO)
trichloroethene  (ISO)
Tungsten carbide  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular space  (IBA,IEA,ISO)

Molecular Function
endothelin B receptor binding  (IBA,IEA,ISO)
hormone activity  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2. Bloch KD, etal., Genomics 1991 May;10(1):236-42.
2. Association between diastolic blood pressure and variants of the endothelin-1 and endothelin-2 genes. Brown MJ, etal., J Cardiovasc Pharmacol. 2000;35(4 Suppl 2):S41-43.
3. Endothelin release during ischaemia and reperfusion of isolated perfused rat hearts. Brunner F, etal., J Mol Cell Cardiol. 1992 Nov;24(11):1291-305.
4. Broadly altered gene expression in blood leukocytes in essential hypertension is absent during treatment. Chon H, etal., Hypertension. 2004 May;43(5):947-51. Epub 2004 Mar 8.
5. Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. Kakinuma Y, etal., Life Sci. 1999;65(16):1671-83.
6. Serum level of endothelin-1 and -2 in pregnancies complicated by EPH gestosis. Leszczynska-Gorzelak B, etal., Gynecol Obstet Invest. 1997;43(1):37-40.
7. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. [Plasma concentrations of endothelin-1 and endothelin-2 in patients with pulmonary hypertension] Salomon P, etal., Pol Merkuriusz Lek. 1999 Sep;7(39):111-3.
15. Quantitative association between a newly identified molecular variant in the endothelin-2 gene and human essential hypertension. Sharma P, etal., J Hypertens. 1999 Sep;17(9):1281-7.
16. Plasma endothelin in patients with acute aortic disease. Wagner A, etal., Resuscitation. 2002 Apr;53(1):71-6.
Additional References at PubMed
PMID:1859843   PMID:2768235   PMID:8587354   PMID:9012511   PMID:9492062   PMID:10194519   PMID:10708518   PMID:12193061   PMID:12193078   PMID:12372435   PMID:12477932   PMID:12507500  
PMID:15489334   PMID:16216902   PMID:16410304   PMID:16602821   PMID:17418814   PMID:18401410   PMID:18516093   PMID:19914214   PMID:21267068   PMID:21383504   PMID:21873635   PMID:22209790  
PMID:23009755   PMID:23209647   PMID:23341629   PMID:23389444   PMID:23469133   PMID:23676500   PMID:24043815   PMID:24194600   PMID:24763822   PMID:24875861   PMID:25085204   PMID:25132557  
PMID:25203536   PMID:25313862   PMID:27482904   PMID:28400616   PMID:31202927   PMID:31228092   PMID:32150249   PMID:37941117   PMID:38355793  


Genomics

Comparative Map Data
Edn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394120,018,403 - 120,024,557 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4120,018,403 - 120,024,557 (+)EnsemblGRCm39 Ensembl
GRCm384120,161,206 - 120,167,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4120,161,206 - 120,167,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv374119,834,029 - 119,839,965 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364119,659,068 - 119,664,996 (+)NCBIMGSCv36mm8
Celera4118,876,990 - 118,882,911 (+)NCBICelera
Cytogenetic Map4D2.1NCBI
cM Map455.77NCBI
EDN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38141,478,775 - 41,484,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl141,478,775 - 41,484,683 (-)EnsemblGRCh38hg38GRCh38
GRCh37141,944,446 - 41,950,354 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36141,717,033 - 41,722,884 (-)NCBINCBI36Build 36hg18NCBI36
Build 34141,613,539 - 41,619,390NCBI
Celera140,227,695 - 40,233,596 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef140,062,640 - 40,068,539 (-)NCBIHuRef
CHM1_1142,060,834 - 42,066,733 (-)NCBICHM1_1
T2T-CHM13v2.0141,348,976 - 41,370,636 (-)NCBIT2T-CHM13v2.0
Edn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85139,036,576 - 139,042,074 (+)NCBIGRCr8
mRatBN7.25133,751,316 - 133,756,814 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5133,751,217 - 133,756,814 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5136,479,131 - 136,484,624 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05138,235,562 - 138,241,057 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05138,256,179 - 138,261,668 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05139,098,472 - 139,106,396 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5139,100,898 - 139,105,792 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05142,891,221 - 142,896,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45140,742,686 - 140,747,580 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15140,747,827 - 140,753,399 (+)NCBI
Celera5132,309,615 - 132,315,113 (+)NCBICelera
Cytogenetic Map5q36NCBI
Edn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555371,228,070 - 1,233,797 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555371,228,062 - 1,233,784 (-)NCBIChiLan1.0ChiLan1.0
EDN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21185,326,860 - 185,334,257 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11184,468,920 - 184,476,318 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0140,777,582 - 40,783,410 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1142,092,811 - 42,098,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl142,092,811 - 42,098,721 (-)Ensemblpanpan1.1panPan2
EDN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1151,647,966 - 1,654,272 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl151,648,077 - 1,654,272 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha151,906,346 - 1,911,819 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0151,736,878 - 1,742,351 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl151,736,155 - 1,742,351 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1151,643,415 - 1,648,886 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0151,703,305 - 1,708,777 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0151,718,751 - 1,724,224 (+)NCBIUU_Cfam_GSD_1.0
Edn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505857,236,189 - 57,239,728 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647423,060,905 - 23,064,566 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647423,061,219 - 23,064,525 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EDN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6169,744,568 - 169,758,283 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16169,751,956 - 169,758,011 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EDN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12091,425,979 - 91,432,609 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2091,426,747 - 91,431,973 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603325,447,580 - 25,453,538 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Edn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624892870,259 - 877,387 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624892861,976 - 879,044 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Edn2
297 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:195
Interacting mature miRNAs:217
Transcripts:ENSMUST00000030384
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12904006Cfq1_mconditioned fear QTL 1 (mouse)4117177646120107755Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
12904002Opfaq9_mopen field activity QTL 9 (mouse)492975790126975790Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
14696689Gdq2_mgrooming duration QTL 2, females (mouse)4100857197124893793Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1300918Stheal4_msoft tissue heal 4 (mouse)Not determined489969627123969747Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
4141330Iva1_misovaleric acid smelling 1 (mouse)Not determined117071971120723203Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
10412072Ssen1_msuseptibility to Sendai virus 1 (mouse)Not determined4109658132133154782Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
13208565Bmiq6_mbody mass index QTL 6 (mouse)4110857197125893793Mouse
1300655Nidds_mnon-insulin-dependent diabetes mellitus in SJL (mouse)Not determined4115030777129465915Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1300689Dob1_mDietary obesity 1 (mouse)Body weight4101574601123127211Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301233Sbw2_msplenomegaly-NZB x NZW 2 (mouse)Not determined494957579128009280Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
15039368Nmrs19_mNAFLD-associated magnetic resonance shift 19 (mouse)490882780124882780Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
1301731Cafq2_mcaffeine metabolism QTL 2 (mouse)Not determined494732255128732454Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
1300580Lbw2_mlupus NZB x NZW 2 (mouse)Not determined498545539128009280Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
12903992Opfaq6_mopen field activity QTL 6 (mouse)4119064995121366497Mouse
11553870Cmmm_mcarcinoma modifier of MSM (mouse)490590668124590781Mouse
1301996Mmtg2_mmodifier of mammary tumor growth 2 (mouse)Not determined4116270979124055180Mouse

Markers in Region
X59556  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384120,166,797 - 120,166,993UniSTSGRCm38
MGSCv374119,839,402 - 119,839,598UniSTSGRCm37
Celera4118,882,348 - 118,882,544UniSTS
Cytogenetic Map4D2.2UniSTS
Whitehead/MRC_RH41572.04UniSTS
Edn2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv374119,839,285 - 119,839,585UniSTSGRCm37
Celera4118,882,231 - 118,882,531UniSTS
Cytogenetic Map4D2.2UniSTS
cM Map4 UniSTS
Edn2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384120,166,680 - 120,166,980UniSTSGRCm38
MGSCv374119,839,285 - 119,839,585UniSTSGRCm37
Celera4118,882,231 - 118,882,531UniSTS
Cytogenetic Map4D2.2UniSTS
Edn2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D2.2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000030384   ⟹   ENSMUSP00000030384
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4120,018,403 - 120,024,557 (+)Ensembl
GRCm38.p6 Ensembl4120,161,206 - 120,167,360 (+)Ensembl
RefSeq Acc Id: NM_007902   ⟹   NP_031928
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394120,018,403 - 120,024,557 (+)NCBI
GRCm384120,161,206 - 120,167,360 (+)NCBI
MGSCv374119,834,029 - 119,839,965 (+)RGD
Celera4118,876,990 - 118,882,911 (+)RGD
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_031928 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH37042 (Get FASTA)   NCBI Sequence Viewer  
  BAA94208 (Get FASTA)   NCBI Sequence Viewer  
  BAQ25522 (Get FASTA)   NCBI Sequence Viewer  
  CAA42155 (Get FASTA)   NCBI Sequence Viewer  
  EDL30430 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000030384
  ENSMUSP00000030384.5
GenBank Protein P22389 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_031928   ⟸   NM_007902
- Peptide Label: preproprotein
- UniProtKB: Q9JME3 (UniProtKB/Swiss-Prot),   P22389 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000030384   ⟸   ENSMUST00000030384

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P22389-F1-model_v2 AlphaFold P22389 1-175 view protein structure

Promoters
RGD ID:6884474
Promoter ID:EPDNEW_M5688
Type:single initiation site
Name:Edn2_1
Description:Mus musculus endothelin 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384120,161,423 - 120,161,483EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95284 AgrOrtholog
Ensembl Genes ENSMUSG00000028635 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000030384 ENTREZGENE
  ENSMUST00000030384.5 UniProtKB/Swiss-Prot
InterPro Endothelin UniProtKB/Swiss-Prot
  Endothelin_toxin_CS UniProtKB/Swiss-Prot
  Endothln-like_toxin UniProtKB/Swiss-Prot
KEGG Report mmu:13615 UniProtKB/Swiss-Prot
MGD MGI:95284 ENTREZGENE
NCBI Gene 13615 ENTREZGENE
PANTHER PTHR13874 UniProtKB/Swiss-Prot
  PTHR13874:SF9 UniProtKB/Swiss-Prot
Pfam Endothelin UniProtKB/Swiss-Prot
PhenoGen Edn2 PhenoGen
PRINTS ENDOTHELIN UniProtKB/Swiss-Prot
PROSITE ENDOTHELIN UniProtKB/Swiss-Prot
SMART END UniProtKB/Swiss-Prot
UniProt EDN2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JME3 ENTREZGENE
UniProt Secondary Q9JME3 UniProtKB/Swiss-Prot