Rnf4 (ring finger protein 4) - Rat Genome Database

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Gene: Rnf4 (ring finger protein 4) Mus musculus
Analyze
Symbol: Rnf4
Name: ring finger protein 4
RGD ID: 737479
MGI Page MGI
Description: Predicted to enable several functions, including SUMO polymer binding activity; TBP-class protein binding activity; and nuclear receptor binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; heart; and musculature. Orthologous to human RNF4 (ring finger protein 4).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AU018689; E3 ubiquitin ligase RNF4; E3 ubiquitin-protein ligase RNF4; gene trap ROSA b-geo 8; Gtrge; Gtrgeo8; RING-type E3 ubiquitin transferase RNF4; SNURF
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm16074  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39534,493,594 - 34,510,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl534,493,633 - 34,512,973 (+)EnsemblGRCm39 Ensembl
GRCm38534,336,250 - 34,353,445 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,336,289 - 34,355,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv37534,679,039 - 34,696,079 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36534,653,247 - 34,670,287 (+)NCBIMGSCv36mm8
Celera531,806,911 - 31,824,034 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.87NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-ethoxyethanol  (ISO)
2-methoxyethanol  (ISO)
2-methylcholine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
5-fluorouracil  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
ciguatoxin CTX1B  (EXP)
colforsin daropate hydrochloride  (ISO)
crocidolite asbestos  (EXP)
cycloheximide  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
fenpyroximate  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (EXP)
genistein  (EXP)
gentamycin  (ISO)
hydrogen cyanide  (EXP)
hydroxyurea  (ISO)
hypochlorous acid  (EXP)
L-methionine  (EXP)
levofloxacin  (ISO)
Methylazoxymethanol acetate  (ISO)
Mono-carboxy isooctyl phthalate  (ISO)
nefazodone  (ISO)
ozone  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
potassium cyanide  (EXP)
progesterone  (ISO)
pyrogallol  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trimellitic anhydride  (EXP)
triptonide  (EXP)
triticonazole  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IDA,ISO,ISS)
microtubule end  (IEA,ISO)
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)
PML body  (IBA,IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3. Down-regulation of estrogen receptor beta and transcriptional coregulator SNURF/RNF4 in testicular germ cell cancer. Hirvonen-Santti SJ, etal., Eur Urol. 2003 Dec;44(6):742-7; discussion 747.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription. Moilanen AM, etal., Mol Cell Biol 1998 Sep;18(9):5128-39.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. SNURF-SNRPN and UBE3A transcript levels in patients with Angelman syndrome. Runte M, etal., Hum Genet. 2004 May;114(6):553-61. Epub 2004 Mar 10.
Additional References at PubMed
PMID:8889548   PMID:9187083   PMID:9479498   PMID:10349636   PMID:10822263   PMID:10849425   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11866449   PMID:12477932   PMID:12520002  
PMID:12874792   PMID:12885770   PMID:12904583   PMID:14610273   PMID:14749358   PMID:14987998   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16971476  
PMID:17762864   PMID:18287559   PMID:18799693   PMID:19779455   PMID:20059953   PMID:20681948   PMID:20696907   PMID:21267068   PMID:21873635   PMID:23028697   PMID:23197296   PMID:24142876  
PMID:24637324   PMID:24714598   PMID:24882209   PMID:24912682   PMID:24969970   PMID:28143738   PMID:34071450   PMID:37064880   PMID:38355793   PMID:38530355  


Genomics

Comparative Map Data
Rnf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39534,493,594 - 34,510,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl534,493,633 - 34,512,973 (+)EnsemblGRCm39 Ensembl
GRCm38534,336,250 - 34,353,445 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,336,289 - 34,355,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv37534,679,039 - 34,696,079 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36534,653,247 - 34,670,287 (+)NCBIMGSCv36mm8
Celera531,806,911 - 31,824,034 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.87NCBI
RNF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3842,469,106 - 2,515,857 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl42,462,220 - 2,515,857 (+)EnsemblGRCh38hg38GRCh38
GRCh3742,470,833 - 2,517,584 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3642,440,605 - 2,487,382 (+)NCBINCBI36Build 36hg18NCBI36
Build 3442,438,037 - 2,484,812NCBI
Celera42,381,995 - 2,428,665 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef42,410,726 - 2,457,392 (+)NCBIHuRef
CHM1_142,468,951 - 2,515,567 (+)NCBICHM1_1
T2T-CHM13v2.042,467,864 - 2,514,631 (+)NCBIT2T-CHM13v2.0
Rnf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81480,625,864 - 80,647,138 (-)NCBIGRCr8
mRatBN7.21476,401,292 - 76,423,270 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1476,401,299 - 76,422,566 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,855,542 - 80,874,657 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01482,096,173 - 82,115,286 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01478,541,415 - 78,560,532 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01481,658,400 - 81,679,756 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1481,660,354 - 81,679,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01482,345,311 - 82,366,467 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41482,092,024 - 82,112,036 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11482,093,652 - 82,114,081 (-)NCBI
Celera1475,327,677 - 75,346,979 (-)NCBICelera
Cytogenetic Map14q21NCBI
Rnf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555141,511,062 - 1,523,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555141,501,943 - 1,525,689 (+)NCBIChiLan1.0ChiLan1.0
RNF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v232,806,077 - 2,853,304 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan142,763,804 - 2,789,272 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v042,614,918 - 2,661,785 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.142,518,559 - 2,565,970 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl42,540,612 - 2,563,937 (+)Ensemblpanpan1.1panPan2
RNF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1361,721,752 - 61,759,797 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl361,723,124 - 61,759,730 (-)EnsemblCanFam3.1canFam3CanFam3.1
Rnf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528567,323,348 - 67,354,145 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647721,025,040 - 21,055,821 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl81,353,658 - 1,380,634 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,353,532 - 1,380,637 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28917,478 - 945,481 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12746,245,786 - 46,290,671 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660512,616,728 - 2,662,730 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475525,141,567 - 25,153,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475525,139,637 - 25,163,586 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf4
554 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2614
Count of miRNA genes:666
Interacting mature miRNAs:814
Transcripts:ENSMUST00000030992, ENSMUST00000181991, ENSMUST00000181999, ENSMUST00000182047, ENSMUST00000182582, ENSMUST00000182583, ENSMUST00000182709, ENSMUST00000182772, ENSMUST00000182810, ENSMUST00000182970, ENSMUST00000183071, ENSMUST00000183265
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
10401122Pgia41_mproteoglycan induced arthritis 41 (mouse)Not determined582314434823280Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse

Markers in Region
RH126561  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,994,759 - 3,994,968UniSTSGRCm38
GRCm38534,353,211 - 34,353,420UniSTSGRCm38
MGSCv37534,695,860 - 34,696,069UniSTSGRCm37
MGSCv37106,351,573 - 6,351,782UniSTSGRCm37
Celera103,922,536 - 3,922,745UniSTS
Celera531,823,815 - 31,824,024UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map5B2UniSTS
RH136248  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,353,008 - 34,353,210UniSTSGRCm38
MGSCv37534,695,657 - 34,695,859UniSTSGRCm37
Celera531,823,612 - 31,823,814UniSTS
Cytogenetic Map5B2UniSTS
UniSTS:236298  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,993,206 - 3,993,299UniSTSGRCm38
GRCm38534,351,647 - 34,351,740UniSTSGRCm38
MGSCv37534,694,296 - 34,694,389UniSTSGRCm37
MGSCv37106,353,242 - 6,353,335UniSTSGRCm37
Celera103,920,983 - 3,921,076UniSTS
Celera531,822,251 - 31,822,344UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map5B2UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001304269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001304270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC104889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF169300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK019656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY050656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY275961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY505719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U95141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030992   ⟹   ENSMUSP00000030992
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,724 - 34,510,780 (+)Ensembl
GRCm38.p6 Ensembl534,336,380 - 34,353,436 (+)Ensembl
Ensembl Acc Id: ENSMUST00000181991
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,734 - 34,507,377 (+)Ensembl
GRCm38.p6 Ensembl534,336,390 - 34,350,033 (+)Ensembl
Ensembl Acc Id: ENSMUST00000181999
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,761 - 34,504,478 (+)Ensembl
GRCm38.p6 Ensembl534,336,417 - 34,347,134 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182047   ⟹   ENSMUSP00000138411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,494,276 - 34,510,768 (+)Ensembl
GRCm38.p6 Ensembl534,336,932 - 34,353,424 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,763 - 34,499,972 (+)Ensembl
GRCm38.p6 Ensembl534,336,419 - 34,342,628 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182583   ⟹   ENSMUSP00000138594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,494,029 - 34,507,374 (+)Ensembl
GRCm38.p6 Ensembl534,336,685 - 34,350,030 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182709   ⟹   ENSMUSP00000138555
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,633 - 34,510,783 (+)Ensembl
GRCm38.p6 Ensembl534,336,289 - 34,353,439 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182772
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,768 - 34,504,770 (+)Ensembl
GRCm38.p6 Ensembl534,336,424 - 34,347,426 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182810
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,494,663 - 34,500,008 (+)Ensembl
GRCm38.p6 Ensembl534,337,319 - 34,342,664 (+)Ensembl
Ensembl Acc Id: ENSMUST00000182970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,672 - 34,507,871 (+)Ensembl
GRCm38.p6 Ensembl534,336,328 - 34,350,527 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183071
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,493,790 - 34,507,212 (+)Ensembl
GRCm38.p6 Ensembl534,336,446 - 34,349,868 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,508,460 - 34,512,973 (+)Ensembl
GRCm38.p6 Ensembl534,351,116 - 34,355,629 (+)Ensembl
RefSeq Acc Id: NM_001304269   ⟹   NP_001291198
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,493,724 - 34,510,789 (+)NCBI
GRCm38534,336,380 - 34,353,445 (+)NCBI
Celera531,806,771 - 31,824,049 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001304270   ⟹   NP_001291199
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,494,276 - 34,510,789 (+)NCBI
GRCm38534,336,932 - 34,353,445 (+)NCBI
Celera531,806,771 - 31,824,049 (+)NCBI
Sequence:
RefSeq Acc Id: NM_011278   ⟹   NP_035408
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,493,594 - 34,510,789 (+)NCBI
GRCm38534,336,250 - 34,353,445 (+)NCBI
MGSCv37534,679,039 - 34,696,079 (+)RGD
Celera531,806,771 - 31,824,049 (+)NCBI
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_035408   ⟸   NM_011278
- UniProtKB: O35941 (UniProtKB/Swiss-Prot),   Q541Z6 (UniProtKB/Swiss-Prot),   Q9QZS2 (UniProtKB/Swiss-Prot),   Q3TXE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291198   ⟸   NM_001304269
- UniProtKB: O35941 (UniProtKB/Swiss-Prot),   Q541Z6 (UniProtKB/Swiss-Prot),   Q9QZS2 (UniProtKB/Swiss-Prot),   Q3TXE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001291199   ⟸   NM_001304270
- UniProtKB: O35941 (UniProtKB/Swiss-Prot),   Q541Z6 (UniProtKB/Swiss-Prot),   Q9QZS2 (UniProtKB/Swiss-Prot),   Q3TXE6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000138555   ⟸   ENSMUST00000182709
Ensembl Acc Id: ENSMUSP00000030992   ⟸   ENSMUST00000030992
Ensembl Acc Id: ENSMUSP00000138594   ⟸   ENSMUST00000182583
Ensembl Acc Id: ENSMUSP00000138411   ⟸   ENSMUST00000182047
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZS2-F1-model_v2 AlphaFold Q9QZS2 1-194 view protein structure

Promoters
RGD ID:6886460
Promoter ID:EPDNEW_M6681
Type:initiation region
Name:Rnf4_1
Description:Mus musculus ring finger protein 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6682  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38534,336,432 - 34,336,492EPDNEW
RGD ID:6886462
Promoter ID:EPDNEW_M6682
Type:initiation region
Name:Rnf4_2
Description:Mus musculus ring finger protein 4 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6681  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38534,336,971 - 34,337,031EPDNEW
RGD ID:6838243
Promoter ID:MM_KWN:41959
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4
Transcripts:NM_011278,   UC008XCC.1,   UC008XCE.1,   UC008XCF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36534,678,896 - 34,679,396 (+)MPROMDB
RGD ID:6838240
Promoter ID:MM_KWN:41960
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4
Transcripts:ENSMUST00000030992
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36534,688,271 - 34,688,771 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1201691 AgrOrtholog
Ensembl Genes ENSMUSG00000029110 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030992 ENTREZGENE
  ENSMUST00000030992.13 UniProtKB/Swiss-Prot
  ENSMUST00000182047 ENTREZGENE
  ENSMUST00000182047.2 UniProtKB/Swiss-Prot
  ENSMUST00000182583.8 UniProtKB/TrEMBL
  ENSMUST00000182709 ENTREZGENE
  ENSMUST00000182709.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RING-HC_RNF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNF4-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19822 UniProtKB/Swiss-Prot
MGD MGI:1201691 ENTREZGENE
NCBI Gene 19822 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING FINGER DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf4 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt O35941 ENTREZGENE
  Q3TXE6 ENTREZGENE, UniProtKB/TrEMBL
  Q3ULB8_MOUSE UniProtKB/TrEMBL
  Q541Z6 ENTREZGENE
  Q9QZS2 ENTREZGENE, UniProtKB/Swiss-Prot
  S4R2C9_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35941 UniProtKB/Swiss-Prot
  Q541Z6 UniProtKB/Swiss-Prot