Rasa3 (RAS p21 protein activator 3) - Rat Genome Database

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Gene: Rasa3 (RAS p21 protein activator 3) Mus musculus
Analyze
Symbol: Rasa3
Name: RAS p21 protein activator 3
RGD ID: 737295
MGI Page MGI
Description: Predicted to enable calcium-release channel activity. Predicted to be involved in intracellular signal transduction and negative regulation of Ras protein signal transduction. Predicted to act upstream of or within cellular response to heat. Predicted to be located in cytoplasmic side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and neural retina. Used to study aplastic anemia. Orthologous to human RASA3 (RAS p21 protein activator 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI326412; C86362; E130011G04; G; GAP1(IP4BP); GAPIII; GAPIII activator 3; hlb38; hlb381; ins P4-binding protein; R-Ras gap; R-ras RTPase activating protein-3; ras GTPase-activating protein 3; Ras GTPase-activating protein III; sc; scat
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,617,218 - 13,727,590 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,616,948 - 13,727,603 (-)EnsemblGRCm39 Ensembl
GRCm38813,567,218 - 13,677,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,566,948 - 13,677,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv37813,567,218 - 13,677,587 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,567,195 - 13,677,549 (-)NCBIMGSCv36mm8
Celera813,734,036 - 13,844,447 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
carbon nanotube  (EXP)
cisplatin  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Muraglitazar  (ISO)
N-ethyl-N-nitrosourea  (EXP)
nicotine  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
pirinixic acid  (EXP)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell cycle checkpoint function  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryonic hematopoiesis  (IAGP)
abnormal erythroblast morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal hemostasis  (IAGP)
abnormal immune system morphology  (IAGP)
abnormal megakaryocyte differentiation  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal platelet cell number  (IAGP)
abnormal platelet physiology  (IAGP)
abnormal pregnancy  (IAGP)
abnormal sleep behavior  (IEA)
abnormal spleen morphology  (IAGP)
abnormal vascular endothelial cell development  (IAGP)
anemia  (IAGP)
anisocytosis  (IAGP)
bone marrow failure  (IAGP)
bruising  (IAGP)
decreased apoptosis  (IAGP)
decreased B cell number  (IAGP)
decreased birth body size  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased circulating glucose level  (IEA)
decreased erythrocyte cell number  (IAGP)
decreased exploration in new environment  (IEA)
decreased hematocrit  (IAGP)
decreased hemoglobin content  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased mean corpuscular hemoglobin  (IAGP)
decreased mean corpuscular hemoglobin concentration  (IAGP)
decreased T cell number  (IAGP)
edema  (IAGP)
embryonic lethality prior to tooth bud stage  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enlarged spleen  (IAGP)
hemolysis  (IAGP)
hemorrhage  (IAGP)
hyperlipidemia  (IAGP)
increased circulating bilirubin level  (IAGP)
increased circulating lactate dehydrogenase level  (IAGP)
increased heart weight  (IEA)
increased hemoglobin concentration distribution width  (IAGP)
increased mean corpuscular volume  (IAGP)
increased mean platelet volume  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased megakaryocyte-erythroid progenitor cell number  (IAGP)
increased red blood cell distribution width  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
internal hemorrhage  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
maternal effect  (IAGP)
oxidative stress  (IAGP)
pale liver  (IAGP)
pale spleen  (IAGP)
pallor  (IAGP)
pancytopenia  (IAGP)
petechiae  (IAGP)
poikilocytosis  (IAGP)
polychromatophilia  (IAGP)
premature death  (IAGP)
prenatal lethality prior to heart atrial septation  (IEA)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
reticulocytosis  (IAGP)
thrombocytopenia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2383655   PMID:7500386   PMID:8334700   PMID:9754557   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11222494   PMID:12477932   PMID:15226823   PMID:15686869  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16829211   PMID:17179160   PMID:20661302   PMID:21267068   PMID:21677750   PMID:22773809   PMID:23221813   PMID:24194600  
PMID:24967784   PMID:25294679   PMID:25705885   PMID:26410627   PMID:27903653   PMID:29381707   PMID:29922180   PMID:30446383   PMID:33341069   PMID:33370780   PMID:37267105  


Genomics

Comparative Map Data
Rasa3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,617,218 - 13,727,590 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,616,948 - 13,727,603 (-)EnsemblGRCm39 Ensembl
GRCm38813,567,218 - 13,677,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,566,948 - 13,677,603 (-)EnsemblGRCm38mm10GRCm38
MGSCv37813,567,218 - 13,677,587 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,567,195 - 13,677,549 (-)NCBIMGSCv36mm8
Celera813,734,036 - 13,844,447 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.29NCBI
RASA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,977,783 - 114,132,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,977,783 - 114,132,623 (-)EnsemblGRCh38hg38GRCh38
GRCh3713114,747,194 - 114,898,098 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613113,765,296 - 113,916,197 (-)NCBINCBI36Build 36hg18NCBI36
Build 3413113,765,296 - 113,916,197NCBI
Celera1395,423,074 - 95,573,004 (-)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1395,016,746 - 95,162,033 (-)NCBIHuRef
CHM1_113114,715,940 - 114,865,735 (-)NCBICHM1_1
T2T-CHM13v2.013113,188,423 - 113,340,668 (-)NCBIT2T-CHM13v2.0
Rasa3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21675,855,360 - 75,969,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1675,855,265 - 75,970,804 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,135,990 - 81,249,957 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01684,588,959 - 84,702,928 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01679,837,128 - 79,951,690 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,320,090 - 81,434,239 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,318,633 - 81,434,363 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,808,492 - 80,922,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41680,710,463 - 80,824,220 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11680,815,596 - 80,825,940 (+)NCBI
Celera1673,663,562 - 73,777,478 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
Rasa3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404141,060 - 225,572 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955404140,906 - 225,278 (+)NCBIChiLan1.0ChiLan1.0
RASA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan113114,144,769 - 114,304,323 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01395,036,382 - 95,195,480 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113114,123,816 - 114,271,066 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13114,123,816 - 114,271,066 (-)Ensemblpanpan1.1panPan2
RASA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12261,093,762 - 61,202,209 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2261,095,044 - 61,202,152 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,805,357 - 60,913,843 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,780,849 - 61,889,450 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,780,855 - 61,889,451 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12261,218,315 - 61,326,769 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02261,225,625 - 61,334,098 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02261,252,037 - 61,360,858 (-)NCBIUU_Cfam_GSD_1.0
Rasa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,992,373 - 196,074,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493703040,116 - 122,490 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493703040,123 - 122,478 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,951,019 - 79,027,900 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,951,017 - 79,027,991 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,685,993 - 86,763,496 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RASA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,848,158 - 91,974,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,848,160 - 91,974,555 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604649,138,040 - 49,271,270 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rasa3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793257,661 - 334,981 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793209,616 - 336,304 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rasa3
3505 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1938
Count of miRNA genes:788
Interacting mature miRNAs:1050
Transcripts:ENSMUST00000117551, ENSMUST00000127418, ENSMUST00000132439, ENSMUST00000132637, ENSMUST00000137822, ENSMUST00000154454
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124751082Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8495000035067154Mouse
1357525Pnhdlc3_mplasma non-HDL cholesterol 3 (mouse)Not determined8721249923753815Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8721249935110107Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8798418941984342Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8810320142103372Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8810320142103372Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8810320142103372Mouse
14697703Stsl1_mSalmonella typhimurium susceptibility locus 1 (mouse)81135000017050016Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81344721035321225Mouse

Markers in Region
C86362  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,567,060 - 13,567,294UniSTSGRCm38
MGSCv37813,567,060 - 13,567,294UniSTSGRCm37
Celera813,733,878 - 13,734,112UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH8140.06UniSTS
AI326412  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,567,317 - 13,567,455UniSTSGRCm38
MGSCv37813,567,317 - 13,567,455UniSTSGRCm37
Celera813,734,135 - 13,734,273UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH8137.1UniSTS
D8Mit60  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,650,751 - 13,650,928UniSTSGRCm38
MGSCv37813,650,751 - 13,650,928UniSTSGRCm37
Celera813,817,591 - 13,817,768UniSTS
Cytogenetic Map8A1.1UniSTS
cM Map86.0UniSTS
Whitehead Genetic84.4UniSTS
Whitehead/MRC_RH8123.74UniSTS
Whitehead_YAC8 UniSTS
Rasa3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,567,615 - 13,568,313UniSTSGRCm38
MGSCv37813,567,615 - 13,568,313UniSTSGRCm37
Celera813,734,433 - 13,735,131UniSTS
Cytogenetic Map8A1.1UniSTS
cM Map8 UniSTS
D16Wox25  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,678,995 - 13,679,110UniSTSGRCm38
MGSCv37813,678,995 - 13,679,110UniSTSGRCm37
Celera813,845,855 - 13,845,970UniSTS
Cytogenetic Map8A1.1UniSTS
Rasa3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38813,568,038 - 13,568,116UniSTSGRCm38
MGSCv37813,568,038 - 13,568,116UniSTSGRCm37
Celera813,734,856 - 13,734,934UniSTS
Cytogenetic Map8A1.1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB052362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA749631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000117551   ⟹   ENSMUSP00000112998
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,616,948 - 13,727,603 (-)Ensembl
GRCm38.p6 Ensembl813,566,948 - 13,677,603 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127418
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,627,470 - 13,628,043 (-)Ensembl
GRCm38.p6 Ensembl813,577,470 - 13,578,043 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,648,095 - 13,727,483 (-)Ensembl
GRCm38.p6 Ensembl813,598,095 - 13,677,483 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132637
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,645,809 - 13,656,108 (-)Ensembl
GRCm38.p6 Ensembl813,595,809 - 13,606,108 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137822
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,616,950 - 13,634,038 (-)Ensembl
GRCm38.p6 Ensembl813,566,950 - 13,584,038 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154454   ⟹   ENSMUSP00000122968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl813,645,810 - 13,727,451 (-)Ensembl
GRCm38.p6 Ensembl813,595,810 - 13,677,451 (-)Ensembl
RefSeq Acc Id: NM_009025   ⟹   NP_033051
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39813,617,218 - 13,727,587 (-)NCBI
GRCm38813,567,218 - 13,677,587 (-)ENTREZGENE
MGSCv37813,567,218 - 13,677,587 (-)RGD
Celera813,734,036 - 13,844,447 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006508734   ⟹   XP_006508797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39813,617,218 - 13,727,590 (-)NCBI
GRCm38813,567,218 - 13,677,542 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033051   ⟸   NM_009025
- UniProtKB: Q6PG24 (UniProtKB/Swiss-Prot),   Q925V1 (UniProtKB/Swiss-Prot),   Q60790 (UniProtKB/Swiss-Prot),   Q3UGJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508797   ⟸   XM_006508734
- Peptide Label: isoform X1
- UniProtKB: Q3UGJ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000122968   ⟸   ENSMUST00000154454
RefSeq Acc Id: ENSMUSP00000112998   ⟸   ENSMUST00000117551
Protein Domains
C2   PH   Ras-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60790-F1-model_v2 AlphaFold Q60790 1-834 view protein structure

Promoters
RGD ID:6843664
Promoter ID:MM_KWN:53703
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung,   Spleen
Transcripts:OTTMUST00000074142
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36813,577,846 - 13,578,346 (-)MPROMDB
RGD ID:6843663
Promoter ID:MM_KWN:53704
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:OTTMUST00000074138
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36813,583,536 - 13,584,036 (-)MPROMDB
RGD ID:8666507
Promoter ID:EPDNEW_M11285
Type:multiple initiation site
Name:Rasa3_2
Description:Mus musculus RAS p21 protein activator 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11286  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38813,584,038 - 13,584,098EPDNEW
RGD ID:6843665
Promoter ID:MM_KWN:53707
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000033833,   ENSMUST00000117551,   OTTMUST00000074139,   OTTMUST00000074141
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36813,677,311 - 13,677,892 (-)MPROMDB
RGD ID:8666509
Promoter ID:EPDNEW_M11286
Type:initiation region
Name:Rasa3_1
Description:Mus musculus RAS p21 protein activator 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11285  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38813,677,583 - 13,677,643EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1197013 AgrOrtholog
Ensembl Genes ENSMUSG00000031453 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000117551 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000154454.8 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RASA3_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_Btk_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19414 UniProtKB/Swiss-Prot
MGD MGI:1197013 ENTREZGENE
NCBI Gene 19414 ENTREZGENE
PANTHER PTHR10194 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS GTPASE-ACTIVATING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BTK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rasa3 PhenoGen
PRINTS TECBTKDOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS_GTPASE_ACTIV_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_BTK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BTK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RasGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49562 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D6RFE0_MOUSE UniProtKB/TrEMBL
  Q3UGJ5 ENTREZGENE, UniProtKB/TrEMBL
  Q60790 ENTREZGENE
  Q6PG24 ENTREZGENE
  Q8C6G4_MOUSE UniProtKB/TrEMBL
  Q925V1 ENTREZGENE
  RASA3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PG24 UniProtKB/Swiss-Prot
  Q925V1 UniProtKB/Swiss-Prot