Itpr2 (inositol 1,4,5-triphosphate receptor 2) - Rat Genome Database

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Gene: Itpr2 (inositol 1,4,5-triphosphate receptor 2) Mus musculus
Analyze
Symbol: Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
RGD ID: 737250
MGI Page MGI
Description: Enables inositol 1,4,5-trisphosphate-gated calcium channel activity and phosphatidylinositol binding activity. Involved in cellular response to cAMP. Acts upstream of or within calcium ion transport and cellular response to ethanol. Located in cell cortex and sarcoplasmic reticulum. Is expressed in several structures, including heart; liver; medulla oblongata; skeletal muscle; and spleen. Used to study isolated anhidrosis with normal sweat glands. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis and isolated anhidrosis with normal sweat glands. Orthologous to human ITPR2 (inositol 1,4,5-trisphosphate receptor type 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI649341; inositol 1,4,5-triphosphate receptor 5; inositol 1,4,5-trisphosphate receptor type 2; inositol 1,4,5-trisphosphate type V receptor; inositol 1,4,5-trisphosphate-gated calcium channel ITPR2; inositol trisphosphate receptor type 2; InsP3R-2; InsP3R-5; insP3R2; Ip; IP3 receptor; IP3R 2; Ip3r2; It; Itpr5; type 2 inositol 1,4,5-trisphosphate receptor; type 2 InsP3 receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396146,009,797 - 146,403,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6146,009,797 - 146,403,721 (-)EnsemblGRCm39 Ensembl
GRCm386146,108,299 - 146,502,258 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6146,108,299 - 146,502,223 (-)EnsemblGRCm38mm10GRCm38
MGSCv376146,060,002 - 146,450,434 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366146,068,650 - 146,459,082 (-)NCBIMGSCv36mm8
Celera6149,142,524 - 149,540,657 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitrophenol  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetazolamide  (EXP)
Adenophostin A  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
antimony trichloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcium atom  (EXP)
calcium oxalate  (ISO)
calcium(0)  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chromium(6+)  (ISO)
chrysene  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
fenpyroximate  (ISO)
fenthion  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
glyoxylic acid  (ISO)
lead(0)  (ISO)
losartan  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methapyrilene  (ISO)
methidathion  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
N-hexadecanoylsphingosine  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenethyl caffeate  (EXP)
phenylephrine  (EXP)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rimonabant  (EXP)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
succimer  (EXP)
tamibarotene  (ISO)
tauroursodeoxycholic acid  (EXP)
tebufenpyrad  (ISO)
thapsigargin  (EXP)
thifluzamide  (ISO)
thioacetamide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (EXP)
tungsten  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
vorinostat  (ISO)
xestospongin C  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Hypoxia modulates gene expression of IP3 receptors in rodent cerebellum. Jurkovicova D, etal., Pflugers Arch. 2007 Jun;454(3):415-25. Epub 2007 Feb 7.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. van Es MA, etal., Lancet Neurol. 2007 Oct;6(10):869-77.
10. Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation. Vanderheyden V, etal., Biochim Biophys Acta. 2009 Jun;1793(6):959-70. doi: 10.1016/j.bbamcr.2008.12.003. Epub 2008 Dec 16.
11. Disrupted placental vitamin D metabolism and calcium signaling in gestational diabetes and pre-eclampsia patients. Varshney S, etal., Endocrine. 2023 Apr;80(1):191-200. doi: 10.1007/s12020-022-03272-9. Epub 2022 Dec 8.
Additional References at PubMed
PMID:8063813   PMID:8889548   PMID:9065779   PMID:9729462   PMID:9794230   PMID:9808793   PMID:9858485   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11694504  
PMID:11696558   PMID:11722588   PMID:11860456   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15201137   PMID:15489334   PMID:15632133   PMID:15713744   PMID:15933266   PMID:16014380  
PMID:16141072   PMID:16141073   PMID:16195467   PMID:16844763   PMID:17327232   PMID:17496801   PMID:17581770   PMID:17890015   PMID:17925404   PMID:18194433   PMID:18241669   PMID:18463250  
PMID:18547250   PMID:18658132   PMID:18692062   PMID:18708078   PMID:19033399   PMID:19068129   PMID:19120126   PMID:19429168   PMID:19528657   PMID:19549843   PMID:19608738   PMID:20189985  
PMID:20203048   PMID:20519450   PMID:20578149   PMID:20616315   PMID:20824138   PMID:21075175   PMID:21267068   PMID:21424589   PMID:21435446   PMID:21436055   PMID:21568942   PMID:21677750  
PMID:21737792   PMID:21818117   PMID:21852551   PMID:21873635   PMID:21960523   PMID:22159127   PMID:22347811   PMID:22472648   PMID:22495310   PMID:22547829   PMID:22615493   PMID:22771532  
PMID:22876307   PMID:23012414   PMID:23019322   PMID:23112168   PMID:23166348   PMID:23185258   PMID:23223241   PMID:23258573   PMID:23382219   PMID:23463619   PMID:23658179   PMID:23702310  
PMID:23761909   PMID:23798419   PMID:24042499   PMID:24415751   PMID:24496246   PMID:24742463   PMID:24901844   PMID:24981861   PMID:25215520   PMID:25232111   PMID:25253859   PMID:25315698  
PMID:25329695   PMID:25429263   PMID:25499268   PMID:25737585   PMID:25894291   PMID:26193638   PMID:26217001   PMID:26273054   PMID:26274565   PMID:26378152   PMID:26410627   PMID:26433454  
PMID:26496414   PMID:27000523   PMID:27064281   PMID:27067238   PMID:27378687   PMID:27514653   PMID:27605617   PMID:27725084   PMID:27777977   PMID:27991861   PMID:28012274   PMID:28063222  
PMID:28132831   PMID:28158491   PMID:28365776   PMID:28419336   PMID:28578927   PMID:28615414   PMID:28742117   PMID:28942427   PMID:28945222   PMID:28962833   PMID:28981616   PMID:29380725  
PMID:29488635   PMID:29706581   PMID:29724785   PMID:30144319   PMID:30169757   PMID:30174118   PMID:30196744   PMID:30212841   PMID:30293136   PMID:30306640   PMID:30455631   PMID:30786075  
PMID:30801845   PMID:31271200   PMID:31273206   PMID:31286141   PMID:31348567   PMID:31444225   PMID:31712577   PMID:31758944   PMID:31954621   PMID:32123907   PMID:32320395   PMID:32325033  
PMID:32541069   PMID:32554809   PMID:32581705   PMID:32609904   PMID:32632168   PMID:32706443   PMID:32790690   PMID:32952549   PMID:33020652   PMID:33086039   PMID:33288910   PMID:33526781  
PMID:33830504   PMID:33830944   PMID:33854148   PMID:34059669   PMID:34139149   PMID:34245686   PMID:34429415   PMID:34494546   PMID:34630045   PMID:34767261   PMID:35494252   PMID:35563706  
PMID:36170823   PMID:36383661   PMID:37142655   PMID:37445783   PMID:37543946   PMID:37773446   PMID:38383567   PMID:38476116   PMID:38851477  


Genomics

Comparative Map Data
Itpr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396146,009,797 - 146,403,757 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6146,009,797 - 146,403,721 (-)EnsemblGRCm39 Ensembl
GRCm386146,108,299 - 146,502,258 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6146,108,299 - 146,502,223 (-)EnsemblGRCm38mm10GRCm38
MGSCv376146,060,002 - 146,450,434 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366146,068,650 - 146,459,082 (-)NCBIMGSCv36mm8
Celera6149,142,524 - 149,540,657 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
ITPR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,335,352 - 26,833,194 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1226,335,352 - 26,833,194 (-)EnsemblGRCh38hg38GRCh38
GRCh371226,488,285 - 26,986,127 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,379,552 - 26,877,398 (-)NCBINCBI36Build 36hg18NCBI36
Build 341226,381,611 - 26,877,398NCBI
Celera1231,634,797 - 32,132,275 (-)NCBICelera
Cytogenetic Map12p11.23NCBI
HuRef1226,258,420 - 26,756,231 (-)NCBIHuRef
CHM1_11226,453,424 - 26,951,168 (-)NCBICHM1_1
T2T-CHM13v2.01226,207,897 - 26,705,197 (-)NCBIT2T-CHM13v2.0
Itpr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84180,759,325 - 181,165,361 (-)NCBIGRCr8
mRatBN7.24179,028,594 - 179,434,657 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4179,027,281 - 179,404,164 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4185,313,424 - 185,690,245 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04181,097,944 - 181,474,767 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04179,718,376 - 180,095,194 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04180,423,452 - 180,800,088 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4180,538,389 - 180,722,358 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04244,585,711 - 244,960,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44183,677,606 - 184,066,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14183,922,730 - 184,311,254 (-)NCBI
Celera4167,526,971 - 167,901,481 (-)NCBICelera
RH 3.4 Map41070.3RGD
Cytogenetic Map4q44NCBI
Itpr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541321,291,110 - 21,719,303 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541321,289,673 - 21,719,610 (-)NCBIChiLan1.0ChiLan1.0
ITPR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21069,981,191 - 70,487,626 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11269,978,015 - 70,484,024 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01259,478,206 - 59,984,572 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11262,093,208 - 62,596,018 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1262,092,241 - 62,596,018 (+)Ensemblpanpan1.1panPan2
ITPR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12720,806,670 - 21,278,638 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2720,805,842 - 21,350,083 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2725,103,914 - 25,581,983 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02721,001,355 - 21,474,042 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2721,001,392 - 21,471,311 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12720,812,377 - 21,283,928 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02720,834,447 - 21,306,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02725,271,849 - 25,744,599 (-)NCBIUU_Cfam_GSD_1.0
Itpr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494582,723,135 - 83,198,963 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936548645,925 - 1,121,888 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936548646,019 - 1,120,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl546,935,932 - 47,464,125 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1546,935,923 - 47,465,681 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2550,482,341 - 50,738,864 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITPR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11126,089,480 - 26,574,621 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1126,089,484 - 26,574,950 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660698,498,077 - 8,981,050 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itpr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475212,360,740 - 12,822,287 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475212,360,796 - 12,820,042 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Itpr2
3969 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3808
Count of miRNA genes:850
Interacting mature miRNAs:1169
Transcripts:ENSMUST00000053273, ENSMUST00000079573, ENSMUST00000111673, ENSMUST00000131890, ENSMUST00000137938, ENSMUST00000139732, ENSMUST00000144557, ENSMUST00000145418, ENSMUST00000155339
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129330484149588044Mouse
14746990Manh61_mmandible shape 61 (mouse)6130156355149588044Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130156355149588044Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
4141536Idd6.2_minsulin dependent diabetes susceptibility 6.2 (mouse)Not determined6143556651146215056Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129330484149588044Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129534979149588044Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129330484149588044Mouse
15092047Wsigrme2_mweek six growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092045Wngrme2_mweek nine growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
1301820Mop1_mmorphine preference 1 (mouse)Not determined6132578005146330736Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
15092052Wsegrme2_mweek seven growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
15092053Wegrme2_mweek eight growth rate, maternal effect 2 (mouse)6140445726147201498Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6129953954149588044Mouse
15092060Wfogrme1_mweek four growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
15092061Wfigrme1_mweek five growth rate, maternal effect 1 (mouse)6140445726147201498Mouse
15092058Lgrme2_mlate growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
4141633Idd6.3_minsulin dependent diabetes susceptibility 6.3 (mouse)Not determined146330484146954059Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
15092056Mgrme1_mmid growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse

Markers in Region
BB062653  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,119,483 - 146,119,564UniSTSGRCm38
MGSCv376146,068,005 - 146,068,086UniSTSGRCm37
Celera6149,150,531 - 149,150,612UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead/MRC_RH61467.04UniSTS
AI649341  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,108,495 - 146,108,577UniSTSGRCm38
MGSCv376146,057,017 - 146,057,099UniSTSGRCm37
Celera6149,139,538 - 149,139,620UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead/MRC_RH61467.09UniSTS
12.MMHAP34FLD3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,476,665 - 146,476,832UniSTSGRCm38
MGSCv376146,425,187 - 146,425,354UniSTSGRCm37
Celera6149,514,259 - 149,514,426UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead_YAC6 UniSTS
14.MMHAP57FLE2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,480,111 - 146,480,211UniSTSGRCm38
MGSCv376146,428,633 - 146,428,733UniSTSGRCm37
Celera6149,517,787 - 149,517,887UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead_YAC6 UniSTS
35.MMHAP94FLD5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv376146,146,029 - 146,146,159UniSTSGRCm37
Celera6149,229,338 - 149,229,468UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead_YAC6 UniSTS
MHAa52a5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,459,923 - 146,460,088UniSTSGRCm38
MGSCv376146,408,445 - 146,408,610UniSTSGRCm37
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead_YAC6 UniSTS
D6Mit294  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,313,436 - 146,313,558UniSTSGRCm38
MGSCv376146,261,958 - 146,262,080UniSTSGRCm37
Celera6149,347,027 - 149,347,155UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.4UniSTS
Whitehead Genetic663.4UniSTS
Whitehead/MRC_RH61469.66UniSTS
D6Mit295  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,313,436 - 146,313,544UniSTSGRCm38
MGSCv376146,261,958 - 146,262,066UniSTSGRCm37
Celera6149,347,027 - 149,347,141UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.6UniSTS
Whitehead Genetic663.4UniSTS
Whitehead/MRC_RH61433.5UniSTS
Whitehead_YAC6 UniSTS
D6Mit371  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,298,100 - 146,298,248UniSTSGRCm38
MGSCv376146,246,622 - 146,246,770UniSTSGRCm37
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead Genetic663.4UniSTS
Z71173  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,111,489 - 146,111,620UniSTSGRCm38
MGSCv376146,060,011 - 146,060,142UniSTSGRCm37
Celera6149,142,533 - 149,142,664UniSTS
Cytogenetic Map6G3UniSTS
cM Map673.0UniSTS
Whitehead/MRC_RH61467.04UniSTS
D6Mit15  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,428,986 - 146,429,238UniSTSGRCm38
MGSCv376146,377,508 - 146,377,760UniSTSGRCm37
Celera6149,463,640 - 149,463,834UniSTS
Cytogenetic Map6G3UniSTS
cM Map674.0UniSTS
Whitehead Genetic666.7UniSTS
Whitehead/MRC_RH61522.41UniSTS
Whitehead_YAC6 UniSTS
Y83m2c2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,248,569 - 146,248,828UniSTSGRCm38
MGSCv376146,197,091 - 146,197,350UniSTSGRCm37
Celera6149,282,139 - 149,282,398UniSTS
Cytogenetic Map6G3UniSTS
cM Map672.4UniSTS
Sspn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386146,224,480 - 146,224,704UniSTSGRCm38
MGSCv376146,173,002 - 146,173,226UniSTSGRCm37
Celera6149,257,939 - 149,258,163UniSTS
Cytogenetic Map6G3UniSTS
cM Map671.55UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006507026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB182288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB182290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC153574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC174928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW049374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB638298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY252197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU207333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU980658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z33908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z71173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000053273   ⟹   ENSMUSP00000049584
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,012,978 - 146,403,410 (-)Ensembl
GRCm38.p6 Ensembl6146,111,480 - 146,501,912 (-)Ensembl
Ensembl Acc Id: ENSMUST00000079573   ⟹   ENSMUSP00000078526
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,009,797 - 146,403,676 (-)Ensembl
GRCm38.p6 Ensembl6146,108,299 - 146,502,178 (-)Ensembl
Ensembl Acc Id: ENSMUST00000111673
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,322,916 - 146,403,376 (-)Ensembl
GRCm38.p6 Ensembl6146,421,418 - 146,501,878 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131890   ⟹   ENSMUSP00000121773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,259,198 - 146,298,484 (-)Ensembl
GRCm38.p6 Ensembl6146,357,700 - 146,396,986 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137938
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,022,093 - 146,048,706 (-)Ensembl
GRCm38.p6 Ensembl6146,120,595 - 146,147,208 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139732   ⟹   ENSMUSP00000119110
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,274,621 - 146,403,721 (-)Ensembl
GRCm38.p6 Ensembl6146,373,123 - 146,502,223 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144557
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,191,984 - 146,195,782 (-)Ensembl
GRCm38.p6 Ensembl6146,290,486 - 146,294,284 (-)Ensembl
Ensembl Acc Id: ENSMUST00000145418
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,283,632 - 146,403,676 (-)Ensembl
GRCm38.p6 Ensembl6146,382,134 - 146,502,178 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155339
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,081,834 - 146,098,458 (-)Ensembl
GRCm38.p6 Ensembl6146,180,336 - 146,196,960 (-)Ensembl
Ensembl Acc Id: ENSMUST00000203292   ⟹   ENSMUSP00000144726
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,081,759 - 146,129,041 (-)Ensembl
GRCm38.p6 Ensembl6146,180,261 - 146,227,543 (-)Ensembl
Ensembl Acc Id: ENSMUST00000204901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6146,132,474 - 146,133,977 (-)Ensembl
GRCm38.p6 Ensembl6146,230,976 - 146,232,479 (-)Ensembl
RefSeq Acc Id: NM_010586   ⟹   NP_034716
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396146,009,797 - 146,403,721 (-)NCBI
GRCm386146,108,299 - 146,502,223 (-)NCBI
MGSCv376146,060,002 - 146,450,434 (-)RGD
Celera6149,139,342 - 149,540,968 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_019923   ⟹   NP_064307
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396146,009,797 - 146,403,721 (-)NCBI
GRCm386146,108,299 - 146,502,223 (-)NCBI
MGSCv376146,060,002 - 146,450,434 (-)RGD
Celera6149,139,342 - 149,540,968 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006507026   ⟹   XP_006507089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396146,080,744 - 146,403,757 (-)NCBI
GRCm386146,179,246 - 146,502,258 (-)NCBI
Sequence:
RefSeq Acc Id: NP_034716   ⟸   NM_010586
- Peptide Label: isoform 2
- UniProtKB: Q9Z329 (UniProtKB/Swiss-Prot),   Q8CED6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_064307   ⟸   NM_019923
- Peptide Label: isoform 1
- UniProtKB: Q61744 (UniProtKB/Swiss-Prot),   Q5DWM5 (UniProtKB/Swiss-Prot),   Q5DWM3 (UniProtKB/Swiss-Prot),   P70226 (UniProtKB/Swiss-Prot),   B2KF91 (UniProtKB/Swiss-Prot),   Q8R3B0 (UniProtKB/Swiss-Prot),   Q9Z329 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006507089   ⟸   XM_006507026
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000144726   ⟸   ENSMUST00000203292
Ensembl Acc Id: ENSMUSP00000119110   ⟸   ENSMUST00000139732
Ensembl Acc Id: ENSMUSP00000078526   ⟸   ENSMUST00000079573
Ensembl Acc Id: ENSMUSP00000049584   ⟸   ENSMUST00000053273
Ensembl Acc Id: ENSMUSP00000121773   ⟸   ENSMUST00000131890
Promoters
RGD ID:6839518
Promoter ID:MM_KWN:48231
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Lung
Transcripts:OTTMUST00000063270
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366146,242,351 - 146,243,792 (-)MPROMDB
RGD ID:6840089
Promoter ID:MM_KWN:48234
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000111674,   OTTMUST00000063039,   OTTMUST00000063040,   OTTMUST00000063266,   UC009ERY.1,   UC009ESA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366146,450,294 - 146,450,794 (-)MPROMDB
RGD ID:6891520
Promoter ID:EPDNEW_M9210
Type:initiation region
Name:Itpr2_1
Description:Mus musculus inositol 1,4,5-triphosphate receptor 2 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386146,502,193 - 146,502,253EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99418 AgrOrtholog
Ensembl Genes ENSMUSG00000030287 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000053273 ENTREZGENE
  ENSMUST00000053273.15 UniProtKB/Swiss-Prot
  ENSMUST00000079573 ENTREZGENE
  ENSMUST00000079573.13 UniProtKB/Swiss-Prot
  ENSMUST00000131890.6 UniProtKB/TrEMBL
  ENSMUST00000139732.4 UniProtKB/TrEMBL
  ENSMUST00000203292.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.80.10.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IP3 receptor type 1 binding core, RIH domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot
  Ins145_P3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  InsP3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc-dom UniProtKB/Swiss-Prot
  RIH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ryanodine_IP3_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16439 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99418 ENTREZGENE
NCBI Gene 16439 ENTREZGENE
PANTHER INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc UniProtKB/Swiss-Prot
  RYDR_ITPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Itpr2 PhenoGen
PRINTS INSP3RECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot
  SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SUL2_MOUSE UniProtKB/TrEMBL
  B2KF89_MOUSE UniProtKB/TrEMBL
  B2KF91 ENTREZGENE
  B2KF92_MOUSE UniProtKB/TrEMBL
  ITPR2_MOUSE UniProtKB/Swiss-Prot
  O54911_MOUSE UniProtKB/TrEMBL
  P70226 ENTREZGENE
  Q3UWL5_MOUSE UniProtKB/TrEMBL
  Q497U9_MOUSE UniProtKB/TrEMBL
  Q5DWM3 ENTREZGENE
  Q5DWM5 ENTREZGENE
  Q61744 ENTREZGENE
  Q8BNX2_MOUSE UniProtKB/TrEMBL
  Q8C0J8_MOUSE UniProtKB/TrEMBL
  Q8CED6 ENTREZGENE, UniProtKB/TrEMBL
  Q8R3B0 ENTREZGENE
  Q9Z329 ENTREZGENE
UniProt Secondary B2KF91 UniProtKB/Swiss-Prot
  P70226 UniProtKB/Swiss-Prot
  Q5DWM3 UniProtKB/Swiss-Prot
  Q5DWM5 UniProtKB/Swiss-Prot
  Q61744 UniProtKB/Swiss-Prot
  Q8R3B0 UniProtKB/Swiss-Prot