Pld2 (phospholipase D2) - Rat Genome Database

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Gene: Pld2 (phospholipase D2) Mus musculus
Analyze
Symbol: Pld2
Name: phospholipase D2
RGD ID: 736771
MGI Page MGI
Description: Enables phospholipase D activity. Acts upstream of or within G protein-coupled receptor internalization. Located in brush border membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and spleen. Orthologous to human PLD2 (phospholipase D2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: choline phosphatase 2; mPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; PLD 2; PLD1C
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,430,318 - 70,448,936 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,430,890 - 70,448,936 (+)EnsemblGRCm39 Ensembl
GRCm381170,539,492 - 70,558,110 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,540,064 - 70,558,110 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,353,666 - 70,371,612 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,356,359 - 70,374,305 (+)NCBIMGSCv36mm8
Celera1178,088,483 - 78,106,417 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-naphthylamine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (EXP)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
arsenite(3-)  (ISO)
aspartame  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-endorphin  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cholesterol  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
decabromodiphenyl ether  (ISO)
dimethylarsinic acid  (ISO)
ethanol  (EXP)
fentanyl  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
FR900359  (ISO)
furan  (ISO)
ganglioside GM1  (ISO)
Goe 6976  (ISO)
hydrogen peroxide  (ISO)
Ilimaquinone  (ISO)
ionomycin  (EXP,ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
linoleic acid  (ISO)
lithocholic acid  (EXP)
loperamide  (ISO)
manganese(II) chloride  (ISO)
methadone  (ISO)
monosodium L-glutamate  (EXP)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
nicotine  (ISO)
ochratoxin A  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosphatidic acid  (ISO)
potassium chloride  (ISO)
prostaglandin E2  (ISO)
reactive oxygen species  (EXP)
SB 203580  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
triphenyl phosphate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Differential changes in phospholipase D and phosphatidate phosphohydrolase activities in ischemia-reperfusion of rat heart. Asemu G, etal., Arch Biochem Biophys. 2005 Apr 1;436(1):136-44.
2. Expression of phospholipase D isozymes in scar and viable tissue in congestive heart failure due to myocardial infarction. Dent MR, etal., J Cell Mol Med. 2004 Oct-Dec;8(4):526-36.
3. Differential expression of phospholipase D isozymes in the hippocampus following kainic acid-induced seizures. Kim SY, etal., J Neuropathol Exp Neurol. 2004 Aug;63(8):812-20.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Ischemic preconditioning upregulates expression of phospholipase D2 in the rat hippocampus. Min do S, etal., Acta Neuropathol. 2007 Aug;114(2):157-62. Epub 2007 Mar 29.
7. Down-regulation of phospholipase D2 mRNA in neonatal rat brainstem and cerebellum after hypoxia-ischemia. Peng JH, etal., Neurochem Res. 2006 Oct;31(10):1191-6. Epub 2006 Oct 6.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Increased activity and intranuclear expression of phospholipase D2 in human renal cancer. Zhao Y, etal., Biochem Biophys Res Commun. 2000 Nov 11;278(1):140-3.
Additional References at PubMed
PMID:8889548   PMID:9307024   PMID:9395408   PMID:9560313   PMID:9813240   PMID:9837959   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11318612  
PMID:11734063   PMID:12466851   PMID:12477932   PMID:12782152   PMID:12813467   PMID:12819125   PMID:14517341   PMID:14654225   PMID:14675200   PMID:14681479   PMID:14718562   PMID:14999815  
PMID:15030398   PMID:15067002   PMID:15598876   PMID:16118212   PMID:16141072   PMID:16141073   PMID:16294323   PMID:17085061   PMID:17541981   PMID:17597824   PMID:18006275   PMID:18423386  
PMID:19652486   PMID:19963059   PMID:20213499   PMID:20705243   PMID:21085684   PMID:21147981   PMID:21267068   PMID:21276418   PMID:21319224   PMID:21444720   PMID:21610093   PMID:21677750  
PMID:21873635   PMID:21930784   PMID:22024166   PMID:22106281   PMID:22134919   PMID:22974101   PMID:23035122   PMID:23109426   PMID:23131846   PMID:23288946   PMID:23362269   PMID:23383154  
PMID:23698760   PMID:23868933   PMID:23898047   PMID:24236206   PMID:24262632   PMID:24813107   PMID:24947526   PMID:25187519   PMID:25233074   PMID:25967349   PMID:26122663   PMID:26282875  
PMID:26392467   PMID:26818087   PMID:27034005   PMID:27299737   PMID:27627745   PMID:27658289   PMID:28484281   PMID:28711718   PMID:28831159   PMID:29033361   PMID:29386256   PMID:29437245  
PMID:29656494   PMID:29674728   PMID:30207376   PMID:30555342   PMID:30811216   PMID:30944160   PMID:31090437   PMID:31391241   PMID:31624287   PMID:32209478   PMID:32325033   PMID:32327488  
PMID:32814056   PMID:32971863   PMID:33368247   PMID:34610470   PMID:35945449   PMID:36700766   PMID:38703555  


Genomics

Comparative Map Data
Pld2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,430,318 - 70,448,936 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,430,890 - 70,448,936 (+)EnsemblGRCm39 Ensembl
GRCm381170,539,492 - 70,558,110 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,540,064 - 70,558,110 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,353,666 - 70,371,612 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,356,359 - 70,374,305 (+)NCBIMGSCv36mm8
Celera1178,088,483 - 78,106,417 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
PLD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38174,807,152 - 4,823,430 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl174,807,152 - 4,823,434 (+)EnsemblGRCh38hg38GRCh38
GRCh37174,710,447 - 4,726,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,657,378 - 4,673,694 (+)NCBINCBI36Build 36hg18NCBI36
Build 34174,657,391 - 4,673,694NCBI
Celera174,725,830 - 4,742,140 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef174,598,848 - 4,615,181 (+)NCBIHuRef
CHM1_1174,719,366 - 4,735,679 (+)NCBICHM1_1
T2T-CHM13v2.0174,697,008 - 4,713,290 (+)NCBIT2T-CHM13v2.0
Pld2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,754,957 - 55,772,819 (+)NCBIGRCr8
mRatBN7.21055,256,326 - 55,274,192 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,256,359 - 55,272,808 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,936,905 - 59,954,680 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,425,411 - 59,443,186 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,924,519 - 54,942,294 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,161,921 - 57,181,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,163,174 - 57,179,730 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,908,891 - 56,926,691 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,388,474 - 57,439,063 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,402,096 - 57,452,684 (+)NCBI
Celera1054,402,188 - 54,419,867 (+)NCBICelera
Cytogenetic Map10q24NCBI
Pld2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,239,177 - 10,250,890 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,239,177 - 10,250,516 (+)NCBIChiLan1.0ChiLan1.0
PLD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21912,415,539 - 12,432,079 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11714,383,741 - 14,400,414 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0174,853,919 - 4,870,254 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1174,843,095 - 4,858,991 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl174,843,217 - 4,858,425 (+)Ensemblpanpan1.1panPan2
PLD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,755,881 - 31,767,131 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,756,433 - 31,767,066 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,895,467 - 31,907,045 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,861,137 - 31,872,703 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,859,919 - 31,872,701 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,827,405 - 31,838,971 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,787,088 - 31,798,653 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0531,963,496 - 31,975,051 (-)NCBIUU_Cfam_GSD_1.0
Pld2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560253,017,042 - 53,030,311 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366772,870,660 - 2,883,567 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366772,870,664 - 2,883,545 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,073,914 - 52,087,809 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,073,913 - 52,087,804 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,192,761 - 54,204,085 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,283,248 - 4,298,034 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,283,521 - 4,298,632 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605917,339,077 - 17,355,649 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pld2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247868,690,461 - 8,702,771 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247868,690,968 - 8,702,213 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pld2
6 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1834
Count of miRNA genes:738
Interacting mature miRNAs:924
Transcripts:ENSMUST00000018429, ENSMUST00000108556, ENSMUST00000108557, ENSMUST00000130678, ENSMUST00000146248, ENSMUST00000157075, ENSMUST00000179806
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
Pld2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B3UniSTS
cM Map1139.0UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001302475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001302476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001361935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011248797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001779917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001779918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH006191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL592547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW047839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY772909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR933736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U87557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000018429   ⟹   ENSMUSP00000018429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,431,132 - 70,448,936 (+)Ensembl
GRCm38.p6 Ensembl1170,540,306 - 70,558,110 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108556   ⟹   ENSMUSP00000104196
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,431,182 - 70,437,224 (+)Ensembl
GRCm38.p6 Ensembl1170,540,356 - 70,546,398 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108557   ⟹   ENSMUSP00000104197
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,431,169 - 70,448,936 (+)Ensembl
GRCm38.p6 Ensembl1170,540,343 - 70,558,110 (+)Ensembl
Ensembl Acc Id: ENSMUST00000130678   ⟹   ENSMUSP00000136566
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,446,464 - 70,448,053 (+)Ensembl
GRCm38.p6 Ensembl1170,555,638 - 70,557,227 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146248
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,446,629 - 70,448,303 (+)Ensembl
GRCm38.p6 Ensembl1170,555,803 - 70,557,477 (+)Ensembl
Ensembl Acc Id: ENSMUST00000157075   ⟹   ENSMUSP00000137247
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,430,890 - 70,432,009 (+)Ensembl
GRCm38.p6 Ensembl1170,540,064 - 70,541,183 (+)Ensembl
Ensembl Acc Id: ENSMUST00000179806
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,444,786 - 70,447,929 (+)Ensembl
GRCm38.p6 Ensembl1170,553,960 - 70,557,103 (+)Ensembl
RefSeq Acc Id: NM_001302475   ⟹   NP_001289404
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,431,098 - 70,448,936 (+)NCBI
GRCm381170,540,272 - 70,558,110 (+)NCBI
Celera1178,088,591 - 78,106,417 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001302476   ⟹   NP_001289405
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,431,098 - 70,437,224 (+)NCBI
GRCm381170,540,272 - 70,546,398 (+)NCBI
Celera1178,088,591 - 78,106,417 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001361935   ⟹   NP_001348864
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,890 - 70,448,936 (+)NCBI
GRCm381170,540,064 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008876   ⟹   NP_032902
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,431,098 - 70,448,936 (+)NCBI
GRCm381170,540,272 - 70,558,110 (+)NCBI
MGSCv371170,353,666 - 70,371,612 (+)RGD
Celera1178,088,591 - 78,106,417 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011248794   ⟹   XP_011247096
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,881 - 70,448,936 (+)NCBI
GRCm381170,540,069 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248795   ⟹   XP_011247097
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,906 - 70,448,936 (+)NCBI
GRCm381170,540,174 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248796   ⟹   XP_011247098
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,318 - 70,448,936 (+)NCBI
GRCm381170,539,492 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248797   ⟹   XP_011247099
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,906 - 70,448,936 (+)NCBI
GRCm381170,540,174 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245660   ⟹   XP_030101520
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,906 - 70,448,936 (+)NCBI
GRCm381170,540,080 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001779917
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,906 - 70,448,936 (+)NCBI
GRCm381170,540,174 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001779918
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,430,906 - 70,448,936 (+)NCBI
GRCm381170,540,174 - 70,558,110 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032902   ⟸   NM_008876
- Peptide Label: isoform 2
- UniProtKB: P97813 (UniProtKB/Swiss-Prot),   Q3UNY4 (UniProtKB/TrEMBL),   Q5SXG5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001289404   ⟸   NM_001302475
- Peptide Label: isoform 1
- UniProtKB: Q3UNY4 (UniProtKB/TrEMBL),   Q6NV49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001289405   ⟸   NM_001302476
- Peptide Label: isoform 3
- UniProtKB: Q80ZW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247096   ⟸   XM_011248794
- Peptide Label: isoform X1
- UniProtKB: P97813 (UniProtKB/Swiss-Prot),   Q5SXG5 (UniProtKB/TrEMBL),   Q3UNY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247097   ⟸   XM_011248795
- Peptide Label: isoform X2
- UniProtKB: Q3UNY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247099   ⟸   XM_011248797
- Peptide Label: isoform X4
- UniProtKB: Q3UNY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247098   ⟸   XM_011248796
- Peptide Label: isoform X3
- UniProtKB: Q3UNY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001348864   ⟸   NM_001361935
- Peptide Label: isoform 4
- UniProtKB: Q3UNY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101520   ⟸   XM_030245660
- Peptide Label: isoform X5
Ensembl Acc Id: ENSMUSP00000136566   ⟸   ENSMUST00000130678
Ensembl Acc Id: ENSMUSP00000104197   ⟸   ENSMUST00000108557
Ensembl Acc Id: ENSMUSP00000104196   ⟸   ENSMUST00000108556
Ensembl Acc Id: ENSMUSP00000137247   ⟸   ENSMUST00000157075
Ensembl Acc Id: ENSMUSP00000018429   ⟸   ENSMUST00000018429
Protein Domains
PH   PLD phosphodiesterase   PX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97813-F1-model_v2 AlphaFold P97813 1-933 view protein structure

Promoters
RGD ID:6821568
Promoter ID:MM_KWN:8223
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day4,   Brain,   Liver,   MEF_B4,   MEF_B6
Transcripts:NM_008876,   OTTMUST00000013635,   OTTMUST00000046904,   UC007JVF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,353,184 - 70,353,684 (+)MPROMDB
RGD ID:8675334
Promoter ID:EPDNEW_M15698
Type:initiation region
Name:Pld2_1
Description:Mus musculus phospholipase D2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381170,540,295 - 70,540,355EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:892877 AgrOrtholog
Ensembl Genes ENSMUSG00000020828 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018429 ENTREZGENE
  ENSMUST00000018429.12 UniProtKB/Swiss-Prot
  ENSMUST00000108556 ENTREZGENE
  ENSMUST00000108556.2 UniProtKB/TrEMBL
  ENSMUST00000108557 ENTREZGENE
  ENSMUST00000108557.10 UniProtKB/TrEMBL
  ENSMUST00000130678.2 UniProtKB/TrEMBL
  ENSMUST00000157075.8 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endonuclease Chain A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLD-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D/transphosphatidylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18806 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:892877 ENTREZGENE
NCBI Gene 18806 ENTREZGENE
PANTHER PHOSPHOLIPASE D2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18896 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLDc_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pld2 PhenoGen
PIRSF Phospholipase_D_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phospholipase D/nuclease UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt J3QK47_MOUSE UniProtKB/TrEMBL
  J3QN26_MOUSE UniProtKB/TrEMBL
  P97813 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UNY4 ENTREZGENE, UniProtKB/TrEMBL
  Q5SXG5 ENTREZGENE, UniProtKB/TrEMBL
  Q6NV49 ENTREZGENE, UniProtKB/TrEMBL
  Q80ZW1 ENTREZGENE, UniProtKB/TrEMBL