Cryba1 (crystallin, beta A1) - Rat Genome Database

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Gene: Cryba1 (crystallin, beta A1) Mus musculus
Analyze
Symbol: Cryba1
Name: crystallin, beta A1
RGD ID: 736651
MGI Page MGI
Description: Enables identical protein binding activity. Acts upstream of or within camera-type eye development. Is expressed in several structures, including eye. Used to study age related macular degeneration 1 and cataract 10 multiple types. Human ortholog(s) of this gene implicated in cataract and cataract 10 multiple types. Orthologous to human CRYBA1 (crystallin beta A1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BA3/; BA3/A1; beta-A1-crystallin; beta-A3/A1-crystallin; beta-crystallin A1; Cry; Cryb; MGC130310
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,609,440 - 77,616,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,609,441 - 77,616,109 (-)EnsemblGRCm39 Ensembl
GRCm381177,718,614 - 77,725,293 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,718,615 - 77,725,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,532,234 - 77,538,795 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,534,927 - 77,541,488 (-)NCBIMGSCv36mm8
Celera1185,217,233 - 85,223,794 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mutation in the betaA3/A1-crystallin encoding gene Cryba1 causes a dominant cataract in the mouse. Graw J, etal., Genomics 1999 Nov 15;62(1):67-73.
2. A splice site mutation in CRYBA1/A3 causing autosomal dominant posterior polar cataract in a Chinese pedigree. Gu Z, etal., Mol Vis. 2010 Feb 5;16:154-60.
3. Autosomal dominant cerulean cataract is associated with a chain termination mutation in the human beta-crystallin gene CRYBB2. Litt M, etal., Hum Mol Genet. 1997 May;6(5):665-8.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Retinal gene profiling in a hereditary rodent model of elevated intraocular pressure. Naskar R and Thanos S, Mol Vis. 2006 Oct 18;12:1199-210.
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. A spontaneous mutation affects programmed cell death during development of the rat eye. Sinha D, etal., Exp Eye Res. 2005 Mar;80(3):323-35. doi: 10.1016/j.exer.2004.09.014.
14. betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development. Sinha D, etal., Mol Cell Neurosci. 2008 Jan;37(1):85-95. Epub 2007 Aug 31.
15. Establishment of a recessive mutant small-eye rat with lens involution and retinal detachment associated with partial deletion and rearrangement of the Cryba1 gene. Yamada T, etal., Biochem J. 2015 Oct 15;471(2):293-305. doi: 10.1042/BJ20150165. Epub 2015 Aug 24.
16. A recurrent mutation in CRYBA1 is associated with an autosomal dominant congenital nuclear cataract disease in a Chinese family. Yang G, etal., Mol Vis. 2011;17:1559-63. Epub 2011 Jun 9.
17. A G-->T splice site mutation of CRYBA1/A3 associated with autosomal dominant suture cataracts in a Chinese family. Yang Z, etal., Mol Vis. 2011;17:2065-71. Epub 2011 Aug 5.
18. A novel T-->G splice site mutation of CRYBA1/A3 associated with autosomal dominant nuclear cataracts in a Chinese family. Yang Z, etal., Mol Vis. 2012;18:1283-8. Epub 2012 May 15.
19. Congenital polymorphic cataract associated with a G to A splice site mutation in the human beta-crystallin gene CRYbetaA3/A1. Yu Y, etal., Mol Vis. 2012;18:2213-20. Epub 2012 Aug 8.
20. Differential proteomics analysis of proteins from human diabetic and age-related cataractous lenses. Zhu J, etal., J Res Med Sci. 2013 Nov;18(11):984-9.
21. Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat. Zigler JS, etal., J Cell Sci. 2011 Feb 15;124(Pt 4):523-31. doi: 10.1242/jcs.078790. Epub 2011 Jan 25.
Additional References at PubMed
PMID:1395724   PMID:2649248   PMID:2901325   PMID:3803920   PMID:6835368   PMID:6896514   PMID:7539358   PMID:7557995   PMID:7626882   PMID:7882978   PMID:8072529   PMID:8211130  
PMID:8425893   PMID:8575764   PMID:8666393   PMID:9177778   PMID:9400939   PMID:9512512   PMID:9573353   PMID:9693140   PMID:10080188   PMID:10349636   PMID:10383433   PMID:10603348  
PMID:10780854   PMID:11042159   PMID:11076861   PMID:11146559   PMID:11217851   PMID:11714668   PMID:12446761   PMID:12477932   PMID:14610273   PMID:14648843   PMID:14717595   PMID:15593327  
PMID:15741512   PMID:15905556   PMID:16141072   PMID:16141073   PMID:16162653   PMID:17213798   PMID:19334279   PMID:20735985   PMID:21179429   PMID:21267068   PMID:21436445   PMID:21873635  
PMID:21998302   PMID:22275127   PMID:22427112   PMID:23201579   PMID:23535650   PMID:23745585   PMID:24468901   PMID:25257511   PMID:25347445   PMID:25461968   PMID:25736717   PMID:26427489  
PMID:26851658   PMID:26863613   PMID:28026019   PMID:28083894   PMID:29959226   PMID:30059908   PMID:30098172   PMID:30683901   PMID:31552301   PMID:33627831   PMID:34239035   PMID:36293380  
PMID:36989286  


Genomics

Comparative Map Data
Cryba1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,609,440 - 77,616,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,609,441 - 77,616,109 (-)EnsemblGRCm39 Ensembl
GRCm381177,718,614 - 77,725,293 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,718,615 - 77,725,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,532,234 - 77,538,795 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,534,927 - 77,541,488 (-)NCBIMGSCv36mm8
Celera1185,217,233 - 85,223,794 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
CRYBA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381729,246,859 - 29,254,494 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1729,246,859 - 29,254,494 (+)EnsemblGRCh38hg38GRCh38
GRCh371727,573,877 - 27,581,512 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,598,001 - 24,605,638 (+)NCBINCBI36Build 36hg18NCBI36
Build 341724,598,000 - 24,605,626NCBI
Celera1724,433,393 - 24,441,030 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,782,531 - 23,790,168 (+)NCBIHuRef
CHM1_11727,636,586 - 27,644,223 (+)NCBICHM1_1
T2T-CHM13v2.01730,189,627 - 30,197,262 (+)NCBIT2T-CHM13v2.0
Cryba1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,106,465 - 63,113,020 (-)NCBIGRCr8
mRatBN7.21062,608,373 - 62,614,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1062,608,383 - 62,614,726 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,240,414 - 67,246,766 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01066,745,921 - 66,752,273 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,215,925 - 62,222,276 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,160,777 - 65,167,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,161,152 - 65,167,494 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,458,061 - 66,480,390 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,758,929 - 63,765,451 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11063,772,566 - 63,776,395 (-)NCBI
Celera1061,589,011 - 61,595,363 (-)NCBICelera
Cytogenetic Map10q24NCBI
Cryba1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,952,988 - 3,959,764 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,952,976 - 3,986,548 (-)NCBIChiLan1.0ChiLan1.0
CRYBA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21935,206,029 - 35,214,046 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,077,466 - 37,095,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01727,522,647 - 27,530,767 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,032,799 - 28,040,525 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,032,809 - 28,040,525 (-)Ensemblpanpan1.1panPan2
CRYBA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,372,507 - 43,378,561 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,372,505 - 43,378,590 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,527,304 - 42,533,358 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0944,189,857 - 44,195,902 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl944,189,855 - 44,195,929 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,972,718 - 42,978,772 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0943,264,979 - 43,271,025 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0943,344,166 - 43,350,220 (+)NCBIUU_Cfam_GSD_1.0
Cryba1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,514,188 - 42,522,476 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,392,105 - 5,400,070 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,392,159 - 5,400,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRYBA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,466,520 - 45,473,092 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,466,051 - 45,473,110 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21229,178,767 - 29,181,605 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRYBA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,005,892 - 23,011,357 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1623,003,874 - 23,011,206 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660757,093,414 - 7,100,122 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cryba1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,771,328 - 1,777,503 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,757,272 - 1,777,735 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cryba1
161 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:146
Count of miRNA genes:136
Interacting mature miRNAs:143
Transcripts:ENSMUST00000078623, ENSMUST00000124178
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117757387380746358Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse

Markers in Region
Cryba1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371177,532,342 - 77,532,985UniSTSGRCm37
Celera1185,217,341 - 85,217,984UniSTS
Cytogenetic Map11B-C1UniSTS
cM Map1144.71UniSTS
D11Bhm151  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,726,328 - 77,726,544UniSTSGRCm38
MGSCv371177,539,830 - 77,540,046UniSTSGRCm37
Celera1185,224,829 - 85,225,045UniSTS
Cytogenetic Map11B-C1UniSTS
cM Map1144.73UniSTS
Cryba1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B-C1UniSTS
Cryba1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B-C1UniSTS
cM Map1144.71UniSTS
Cryba1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381177,718,840 - 77,719,483UniSTSGRCm38
MGSCv371177,532,342 - 77,532,985UniSTSGRCm37
Celera1185,217,341 - 85,217,984UniSTS
Cytogenetic Map11B-C1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000078623   ⟹   ENSMUSP00000077693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1177,609,453 - 77,616,109 (-)Ensembl
GRCm38.p6 Ensembl1177,718,627 - 77,725,283 (-)Ensembl
Ensembl Acc Id: ENSMUST00000124178
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1177,609,441 - 77,612,660 (-)Ensembl
GRCm38.p6 Ensembl1177,718,615 - 77,721,834 (-)Ensembl
RefSeq Acc Id: NM_001313933   ⟹   NP_001300862
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,609,440 - 77,616,119 (-)NCBI
GRCm381177,718,614 - 77,725,293 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009965   ⟹   NP_034095
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391177,609,440 - 77,616,119 (-)NCBI
GRCm381177,718,614 - 77,725,293 (-)NCBI
MGSCv371177,532,234 - 77,538,795 (-)RGD
Celera1185,217,233 - 85,223,794 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034095   ⟸   NM_009965
- Peptide Label: isoform 1
- UniProtKB: P02525 (UniProtKB/Swiss-Prot),   Q9QXC6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001300862   ⟸   NM_001313933
- Peptide Label: isoform 2
- UniProtKB: Q9QXC6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000077693   ⟸   ENSMUST00000078623
Protein Domains
Beta/gamma crystallin 'Greek key'

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P02525-F1-model_v2 AlphaFold P02525 1-198 view protein structure

Promoters
RGD ID:6820665
Promoter ID:MM_KWN:8624
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   Brain,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000018595
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361177,534,396 - 77,536,332 (-)MPROMDB
RGD ID:6849528
Promoter ID:EP07069
Type:single initiation site
Name:MM_CRBA
Description:beta-crystallin, CRYBA1 gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:lens
Experiment Methods:Nuclease protection with homologous sequence ladder
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv371177,536,294 - 77,536,354EPD
MGSCv361177,536,294 - 77,536,354EPD
RGD ID:8675648
Promoter ID:EPDNEW_M15855
Type:multiple initiation site
Name:Cryba1_1
Description:Mus musculus crystallin, beta A1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381177,725,286 - 77,725,346EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88518 AgrOrtholog
Ensembl Genes ENSMUSG00000000724 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000078623 ENTREZGENE
  ENSMUST00000078623.5 UniProtKB/TrEMBL
Gene3D-CATH Crystallins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta/Gamma-Crystallin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Beta/gamma_crystallin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_crystallin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12957 UniProtKB/TrEMBL
MGD MGI:88518 ENTREZGENE
NCBI Gene 12957 ENTREZGENE
PANTHER BETA-CRYSTALLIN A3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BETA/GAMMA CRYSTALLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Crystall UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cryba1 PhenoGen
PRINTS BGCRYSTALLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CRYSTALLIN_BETA_GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART XTALbg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CRBA1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9QXC6 ENTREZGENE, UniProtKB/TrEMBL