SQSTM1 (sequestosome 1) - Rat Genome Database

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Gene: SQSTM1 (sequestosome 1) Homo sapiens
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Symbol: SQSTM1
Name: sequestosome 1
RGD ID: 736484
HGNC Page HGNC:11280
Description: Enables several functions, including SH2 domain binding activity; enzyme binding activity; and modification-dependent protein binding activity. Involved in several processes, including macroautophagy; negative regulation of ferroptosis; and regulation of signal transduction. Located in several cellular components, including P-body; PML body; and vacuole. Is active in autophagosome; cytosol; and intracellular non-membrane-bounded organelle. Implicated in Paget's disease of bone; Paget's disease of bone 3; distal myopathy with rimmed vacuoles; frontotemporal dementia and/or amyotrophic lateral sclerosis 3; and neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: A170; autophagy receptor p62; DMRV; EBI3-associated protein of 60 kDa; EBI3-associated protein p60; EBIAP; FTDALS3; NADGP; OSIL; oxidative stress induced like; p60; p62; p62B; PDB3; phosphotyrosine independent ligand for the Lck SH2 domain p62; phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; sequestosome-1; ubiquitin-binding protein p62; ZIP3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: SQSTM1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,806,393 - 179,838,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,806,398 - 179,838,078 (+)EnsemblGRCh38hg38GRCh38
GRCh375179,233,393 - 179,265,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,180,503 - 179,197,684 (+)NCBINCBI36Build 36hg18NCBI36
Build 345179,180,502 - 179,197,681NCBI
Celera5174,858,545 - 174,890,234 (+)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,959,564 - 173,990,246 (+)NCBIHuRef
CHM1_15178,665,789 - 178,697,494 (+)NCBICHM1_1
T2T-CHM13v2.05180,361,589 - 180,393,289 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model