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Gene: Dync1li1 (dynein cytoplasmic 1 light intermediate chain 1) Mus musculus

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Symbol:

Dync1li1

Name:

dynein cytoplasmic 1 light intermediate chain 1

RGD ID:

736406

MGI Page

MGI

Description:

Predicted to enable several functions, including GDP binding activity; dynein heavy chain binding activity; and identical protein binding activity. Predicted to be involved in several processes, including cellular response to nerve growth factor stimulus; early endosome to recycling endosome transport; and regulation of cell cycle process. Predicted to be located in cytoplasmic vesicle; kinetochore; and spindle pole. Predicted to be part of cytoplasmic dynein complex. Predicted to colocalize with centrosome. Orthologous to human DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

1110053F02Rik; cytoplasmic dynein 1 light intermediate chain 1; DLC-A; Dlic1; Dncl; Dnclic1; dynein light chain A; dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate chain 1; LIC; LIC-1; MGC32416; MGC:32416

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	114,517,899 - 114,552,856 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	114,517,858 - 114,553,370 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	114,688,831 - 114,723,788 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	114,688,790 - 114,724,302 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	114,597,949 - 114,632,906 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	114,537,529 - 114,572,486 (+)	NCBI		MGSCv36	mm8
Celera	9	115,163,888 - 115,198,850 (+)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	64.96	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2-ethoxyethanol (ISO)

2-methoxyethanol (ISO)

acrolein (ISO)

alpha-pinene (ISO)

ammonium chloride (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzatropine (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-lapachone (ISO)

beta-naphthoflavone (ISO)

bisphenol A (ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (EXP)

caffeine (ISO)

ciguatoxin CTX1B (EXP)

clozapine (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

deoxynivalenol (EXP)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

entinostat (ISO)

enzyme inhibitor (ISO)

ethanol (EXP)

folic acid (EXP)

FR900359 (ISO)

hexadecanoic acid (ISO)

hydralazine (ISO)

ivermectin (ISO)

lead diacetate (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methoxychlor (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (ISO)

phenol red (ISO)

pirinixic acid (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

thioacetamide (ISO)

thiram (ISO)

Tributyltin oxide (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

cellular response to nerve growth factor stimulus (ISO)

early endosome to recycling endosome transport (IEA,ISO)

microtubule cytoskeleton organization (IBA)

microtubule-based movement (IBA,IEA,ISO,ISS)

positive regulation of mitotic cell cycle spindle assembly checkpoint (IEA,ISO,ISS)

regulation of centrosome cycle (ISO)

regulation of vesicle-mediated transport (IEA,ISO,ISS)

Cellular Component

centrosome (IBA,IEA,ISO)

chromosome (IEA)

chromosome, centromeric region (IEA)

cytoplasm (IEA)

cytoplasmic dynein complex (IBA,IEA,ISO,ISS)

cytoskeleton (IEA)

dynein complex (IEA)

endocytic vesicle membrane (IEA,ISO,ISS)

endosome (IEA)

kinetochore (IEA,ISO,ISS)

late endosome (ISO)

membrane (IEA)

microtubule (IEA)

recycling endosome membrane (IEA)

spindle pole (IEA,ISO,ISS)

Molecular Function

ATP binding (IEA)

dynein heavy chain binding (IBA,IEA,ISO)

GDP binding (IEA,ISO)

GTP binding (ISO)

identical protein binding (ISO)

microtubule motor activity (ISS)

molecular adaptor activity (ISO)

nucleotide binding (IEA)

protein binding (ISO)

protein-macromolecule adaptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondria transport pathway (ISO)

vasopressin signaling pathway via receptor type 2 (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal action potential (IAGP)

abnormal dendrite morphology (IAGP)

abnormal gait (IAGP)

abnormal liver morphology (IEA)

abnormal lung morphology (IEA)

abnormal lysosome physiology (IAGP)

abnormal neuronal migration (IAGP)

abnormal seminal vesicle morphology (IEA)

abnormal skin morphology (IEA)

abnormal sternum morphology (IEA)

abnormal testis morphology (IEA)

decreased exploration in new environment (IAGP)

enlarged lymph nodes (IEA)

enlarged prostate gland (IEA)

increased anxiety-related response (IAGP)

increased defecation amount (IAGP)

increased grip strength (IAGP)

increased red blood cell distribution width (IEA)

microphthalmia (IEA)

mydriasis (IEA)

preweaning lethality, incomplete penetrance (IEA)

small heart (IEA)

small kidney (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Cytoplasmic dynein.	Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
4.	MGDs mouse GO annotations	MGD data from the GO Consortium
5.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
7.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Recruitment of dynein to late endosomes and lysosomes through light intermediate chains.	Tan SC, etal., Mol Biol Cell. 2011 Feb 15;22(4):467-77. doi: 10.1091/mbc.E10-02-0129. Epub 2010 Dec 17.

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:10922068	PMID:10932191	PMID:11042159	PMID:11076861	PMID:11243854	PMID:12477932	PMID:12520002	PMID:12904583	PMID:14610273	PMID:15345747
PMID:15489334	PMID:15782199	PMID:16141072	PMID:16141073	PMID:16260502	PMID:16452087	PMID:16512683	PMID:16602821	PMID:17967808	PMID:18799693	PMID:21471385	PMID:21677750
PMID:21873635	PMID:22193958	PMID:22922362	PMID:23375831	PMID:23628724	PMID:25921334	PMID:26496610	PMID:27510948	PMID:28706196	PMID:30457570	PMID:31040226	PMID:32325033
PMID:32554809	PMID:32581705	PMID:33137126	PMID:34050187	PMID:35727824	PMID:36293380	PMID:36417873	PMID:38355793

Genomics

Comparative Map Data

Dync1li1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	114,517,899 - 114,552,856 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	114,517,858 - 114,553,370 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	9	114,688,831 - 114,723,788 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	114,688,790 - 114,724,302 (+)	Ensembl			mm10	GRCm38
MGSCv37	9	114,597,949 - 114,632,906 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	9	114,537,529 - 114,572,486 (+)	NCBI		MGSCv36	mm8
Celera	9	115,163,888 - 115,198,850 (+)	NCBI		Celera
Cytogenetic Map	9	F3	NCBI
cM Map	9	64.96	NCBI

DYNC1LI1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	32,525,974 - 32,570,858 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	32,525,974 - 32,570,858 (-)	Ensembl			hg38	GRCh38
GRCh37	3	32,567,466 - 32,612,350 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	32,542,470 - 32,587,346 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	3	32,504,552 - 32,549,458 (-)	NCBI		Celera
Cytogenetic Map	3	p22.3	NCBI
HuRef	3	32,502,312 - 32,547,668 (-)	NCBI		HuRef
CHM1_1	3	32,517,445 - 32,562,297 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	32,522,924 - 32,567,802 (-)	NCBI		T2T-CHM13v2.0

Dync1li1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	123,254,823 - 123,288,496 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	8	123,254,859 - 123,289,167 (+)	Ensembl				GRCr8
mRatBN7.2	8	114,376,649 - 114,410,297 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	114,376,662 - 114,410,934 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	8	119,993,673 - 120,027,564 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	118,192,922 - 118,226,802 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	116,035,754 - 116,069,647 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	122,743,274 - 122,776,801 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	122,743,189 - 122,776,806 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	8	122,055,383 - 122,088,910 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	8	119,103,884 - 119,137,411 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	8	113,623,555 - 113,657,074 (+)	NCBI		Celera
RGSC_v3.1	8	119,123,620 - 119,157,148 (+)	NCBI
Cytogenetic Map	8	q32	NCBI

Dync1li1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955620	46,556 - 82,595 (-)	Ensembl
ChiLan1.0	NW_004955620	46,535 - 82,595 (-)	NCBI	ChiLan1.0	ChiLan1.0

DYNC1LI1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	32,503,341 - 32,549,695 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	32,508,120 - 32,554,514 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	32,450,693 - 32,495,400 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	32,758,407 - 32,804,117 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	32,758,407 - 32,804,117 (-)	Ensembl			panPan2	panpan1.1

DYNC1LI1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	12,235,539 - 12,283,851 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	12,235,104 - 12,277,031 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	12,210,519 - 12,258,652 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	12,526,271 - 12,574,477 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	12,525,836 - 12,568,653 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	12,328,096 - 12,376,225 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	12,437,857 - 12,517,703 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	12,474,796 - 12,522,987 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dync1li1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	189,873,315 - 189,903,941 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	23,009,351 - 23,042,439 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936473	23,011,888 - 23,042,497 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DYNC1LI1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	18,506,194 - 18,558,007 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	18,507,710 - 18,558,057 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	20,309,319 - 20,330,876 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DYNC1LI1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	77,025,416 - 77,073,958 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	77,026,235 - 77,073,859 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666041	50,380,599 - 50,431,820 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dync1li1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	10,593,940 - 10,625,052 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624788	10,593,647 - 10,624,755 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Dync1li1
1344 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	288
Count of miRNA genes:	240
Interacting mature miRNAs:	258
Transcripts:	ENSMUST00000047404
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357461	Idd2_m	insulin dependent diabetes susceptibility 2 (mouse)			Not determined		9	82792386	116792481	Mouse
18182932	Metl3_m	metabolite locus 3, N-acetylglutamate (mouse)					9	89440541	123440541	Mouse
1301649	Psl1_m	promotion susceptibility QTL 1 (mouse)			Not determined		9	89289476	123289595	Mouse
1302103	Dob2_m	dietary obesity 2 (mouse)			Not determined		9	86121898	120118690	Mouse
1357648	Obq18_m	obesity QTL 18 (mouse)			Not determined		9	101829255	124359700	Mouse
12904961	Gmmq7_m	gastrocnemius muscle mass QTL 7 (mouse)					9	91560372	124359700	Mouse
1300884	Sluc11_m	susceptibility to lung cancer 11 (mouse)			Not determined		9	82792386	116792481	Mouse
10412242	Alpq8_m	alcohol preference QTL 8 (mouse)			Not determined		9	89162124	123162124	Mouse
1357657	Pymr_m	Plasmodium yoelli malaria resistance (mouse)			Not determined		9	89859058	118767089	Mouse
1301789	Pbwg4_m	postnatal body weight growth 4 (mouse)			Not determined		9	103118511	124359700	Mouse
14746992	Manh67_m	mandible shape 67 (mouse)					9	93865836	124359700	Mouse
10766454	Char10_m	P. chabaudi malaria resistance QTL 10 (mouse)					9	82792386	116792481	Mouse
4141545	Tailaq2_m	tail length adjusted QTL 2 (mouse)			Not determined			63239711	120191934	Mouse
1300549	Bbaa17_m	B. burgdorferi-associated arthritis 17 (mouse)			Not determined		9	86107600	120107729	Mouse
1357635	Splq4_m	spleen weight QTL 4 (mouse)			Not determined		9	63239711	120191934	Mouse
10412290	Pvacm1l_m	plasma vascular cell adhesion molecule 1 levels (mouse)			Not determined		9	103118511	124359700	Mouse
12879896	Berr3_m	berghei resistance locus 3 (mouse)					9	103118511	124359700	Mouse
12880422	V25Dq6_m	vitamin D inactive form serum level QTL 6 (mouse)					9	87677199	121677199	Mouse
1302001	Bdln5_m	body length 5 (mouse)			Not determined		9	93591658	124359700	Mouse
1301297	Lcho1_m	liver cholesterol 1 (mouse)			Not determined		9	100889929	124359700	Mouse
11537364	Cnes5_m	C. neoformans susceptibility locus 5 (mouse)					9	96746658	124359700	Mouse
12904937	Edlmmq9_m	extensor digitorum longus muscle mass QTL 9 (mouse)					9	91560372	124359700	Mouse
11251716	Siim2_m	stress induced immobility 2 (mouse)					9	86625682	120625682	Mouse
1357627	Tgq2_m	triglyceride QTL 2 (mouse)			Not determined		9	101829255	124359700	Mouse
12910773	Splic3_m	spleen iron content 3 (mouse)					9	91291078	124359700	Mouse
12910772	Lvic6_m	liver iron content 6 (mouse)					9	91291078	124359700	Mouse
13463480	Mchcq2_m	mean corpuscular hemoglobin concentration QTL 2 (mouse)					9	91518283	124359700	Mouse
4141833	W10q13_m	weight 10 weeks QTL 13 (mouse)			Not determined			63239711	120191934	Mouse
1301732	Char1_m	P. chabaudi malaria resistance QTL 1 (mouse)			Not determined		9	81680321	115680445	Mouse
12910770	Splic1_m	spleen iron content 1 (mouse)					9	91291078	124359700	Mouse
12904947	Tammq7_m	tibialis anterior muscle mass QTL 7 (mouse)					9	91560372	124359700	Mouse
1558767	Skmw11_m	skeletal muscle weight 11 (mouse)			Not determined		9	91518283	124359700	Mouse
13463477	Rbc9_m	red blood cell count 9 (mouse)					9	91518283	124359700	Mouse
13463478	Mchq18_m	mean corpuscular hemoglobin QTL 18 (mouse)					9	91518283	124359700	Mouse
1301487	Nociq1_m	nociceptive sensitivity inflammatory QTL 1 (mouse)			Not determined		9	84406017	118406120	Mouse
13515058	Adip20d_m	adiposity 20d (mouse)					9	108744078	118744078	Mouse
13463475	Hctq7_m	hematocrit QTL 7 (mouse)					9	91518283	124359700	Mouse
13463474	Hbbcq5_m	hemoglobin concentration QTL 5 (mouse)					9	91518283	124359700	Mouse
1301484	Bwq6_m	body weight (mouse)			Not determined		9	93591658	124359700	Mouse

Markers in Region

UniSTS:236269

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	114,705,064 - 114,705,165	UniSTS	GRCm38
MGSCv37	9	114,614,182 - 114,614,283	UniSTS	GRCm37
Celera	9	115,180,107 - 115,180,208	UniSTS
Cytogenetic Map	9	F3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_146229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC161419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK004235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK082950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK159702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK159983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK180961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK189933	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK191001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK191112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK191959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK193282	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK194365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK195148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK195418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK196819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK197477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK197747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK198065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK201083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK202293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK202548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK204826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK205150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK205923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK207398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK213717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK216247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK217382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK218794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC023347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC129879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000047404 ⟹ ENSMUSP00000035366

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	114,517,858 - 114,553,370 (+)	Ensembl
GRCm38.p6 Ensembl	9	114,688,790 - 114,724,302 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000215345

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	114,517,858 - 114,535,739 (+)	Ensembl
GRCm38.p6 Ensembl	9	114,688,790 - 114,706,671 (+)	Ensembl

RefSeq Acc Id:

NM_146229 ⟹ NP_666341

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	114,517,899 - 114,552,856 (+)	NCBI
GRCm38	9	114,688,831 - 114,723,788 (+)	ENTREZGENE
MGSCv37	9	114,597,949 - 114,632,906 (+)	RGD
Celera	9	115,163,888 - 115,198,850 (+)	RGD
cM Map	9		ENTREZGENE

Sequence:

show sequence

CGCCGCTTCGTTCTTCCAGCCCTGTCAGGAGTGGTGTGATTCCCGACCAAGATGGCGGCCGTGG
GGCGAGTCGGCTCGTTCGGTTCATCTCCACCCGGGCTAGCCTCGACCTACGCCAGCGGACCCCT
AGCCAACGAGCTAGCGTCGGGCAGCGGCGGCCCCGCGGCGGGCGACGATGAGGACGGGCAGAAC
CTTTGGTCCTGCATCCTCAGCGAGGTCTCCACGCGCTCGCGCTCCAAGCTCCCGACCGGGAAGA
ACGTGCTGCTGCTGGGTGAAGATGGAGCTGGGAAGACAAGCCTCATAAGAAGAATTCAGGGCAT
AGAGGAGTACAAGAAGGGAAGAGGACTGGAGTACCTGTACTTAAATGTGCACGACGAAGACAGG
GATGATCAAACAAGATGTAATGTATGGATCTTAGATGGAGATCTGTACCACAAAGGGCTACTCA
AGTTCTCTCTGGATGCCCTTTCTCTGAGGGACACTCTGGTCATGTTGGTTGTTGATATGTCAAA
GCCTTGGACTGCTTTGGATTCCTTACAGAAATGGGCAAGTGTGGTGAGAGAACATGTCGACAAG
CTGAAAATCCCCCCTGAAGAGATGAAGGAAATGGAGCAGAAGTTGATTAGAGACTTCCAAGAGT
ACGTGGAGCCAGGAGAAGACTTCCCAGCCTCCCCTCAGCGAAGAACCACTGGTGCGCAGGAGGA
CAGAGGTGACAGTGTTGTCCTGCCCCTGGGTGCAGACACACTCACACACAACCTGGGCCTACCA
GTGCTCGTAGTCTGTACGAAGTGTGATGCCATTAGTGTATTGGAGAAAGAGCATGACTACAGAG
ATGAACACTTCGATTTTATCCAGTCTCACATCCGCAAGTTCTGTTTACAGTATGGCGCAGCGCT
GATTTACACTTCAGTAAAAGAGAACAAGAACATAGACTTAGTTTATAAATACATCGTCCAGAAG
CTGTACGGGTTCCCGTACAAGATCCCTGCGGTGGTGGTGGAGAAGGACGCAGTGTTTATTCCAG
CAGGGTGGGATAATGATAAGAAAATAGGAATATTACATGAAAATTTTCAGACTTTGAAAGTAGA
AGATAATTTTGAAGACATCATAACCAAACCTCCTGTCAGAAAGTTCGTGCATGAGAAGGAGATC
ATGGCAGAAGATGACCAAGTGTTTCTGATGAAGCTACAGTCTCTTTTAGCAAAGCAACCTCCAA
CTGCAGCTGGAAGGCCTGTGGATGCATCACCAAGAGTCCCTGGAGGCTCCCCTCGAACACCAAA
CAGATCTGTGTCATCCAATGTTGCCAGTGTGTCCCCCATCCCTGCTGGATCCAAAAAAATTGAT
CCAAACATGAAAGCTGGAGCGACCAGCGAAGGGGTCCTGGCGAATTTCTTCAACAGTCTGTTGA
GTAAGAAGACTGGCTCTCCTGGAGGCCCCGGGGTCGGCGGCAGTCCTGGAGGAGGGGCTGCAGG
TGCAAGCCCCAGTTTGCCACCGTCCGCCAAAAAGTCAGGCCAGAAACCTGTGCTTTCAGATGTT
CACGCAGAGCTAGACAGAATCACACGGAAACCTGCTTCTGTTTCTCCTACAACACCTACATCTC
CTACGGAAGGAGAAGCCTCCTGAAGATACCAAACAAAGCCATTTGTTCATTCTTCTGGGTAATG
ACAGCTTGCCTCTGCCCTGCCCTTCCAAGTTGGAACTACGATGGGGCCGGAAGCTTTTACAAAC
AGACAAAGTTTATGTCCTTATGTCCTTTTTTTTTTTTTTTTGGTGGCTGCCCATTTTTAAAAGA
GGAACTACACAGAAGAAAGACAGGTTTTTTTTTTTTTTTGGTTTTTCGAGACAGGATTTCTCTG
TATAGCCCTGGCTGTCCCAGAACTCACTTTGTAGACCAGGCTGGCCTCAAACTCAGAAATCCTC
CTGCCTCTGCCTCCGGTGTGCGCCACCAGGACCGGCTAAGAAAGACAATTTTACATTATGTAGA
ATAACTGTTTGCATTGCCATTCTGCAAAATGAAGAAATTTTGATTTTTGAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_666341	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH23347	(Get FASTA)	NCBI Sequence Viewer
	AAI29880	(Get FASTA)	NCBI Sequence Viewer
	BAE35301	(Get FASTA)	NCBI Sequence Viewer
	BAE35534	(Get FASTA)	NCBI Sequence Viewer
	EDL09299	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000035366
	ENSMUSP00000035366.7
GenBank Protein	Q8R1Q8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_666341 ⟸ NM_146229

- UniProtKB:

Q8R1Q8 (UniProtKB/Swiss-Prot), Q3TWG5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVGRVGSFGSSPPGLASTYASGPLANELASGSGGPAAGDDEDGQNLWSCILSEVSTRSRSKL
PTGKNVLLLGEDGAGKTSLIRRIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVWILDGDLYH
KGLLKFSLDALSLRDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPPEEMKEMEQKLIR
DFQEYVEPGEDFPASPQRRTTGAQEDRGDSVVLPLGADTLTHNLGLPVLVVCTKCDAISVLEKE
HDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYIVQKLYGFPYKIPAVVVEKDA
VFIPAGWDNDKKIGILHENFQTLKVEDNFEDIITKPPVRKFVHEKEIMAEDDQVFLMKLQSLLA
KQPPTAAGRPVDASPRVPGGSPRTPNRSVSSNVASVSPIPAGSKKIDPNMKAGATSEGVLANFF
NSLLSKKTGSPGGPGVGGSPGGGAAGASPSLPPSAKKSGQKPVLSDVHAELDRITRKPASVSPT
TPTSPTEGEAS

hide sequence

Ensembl Acc Id:

ENSMUSP00000035366 ⟸ ENSMUST00000047404

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R1Q8-F1-model_v2	AlphaFold	Q8R1Q8	1-523	view protein structure

Promoters

RGD ID:

6844445

Promoter ID:

MM_KWN:59026

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6

Transcripts:

ENSMUST00000047404, UC009RXX.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	9	114,597,569 - 114,598,069 (+)	MPROMDB

RGD ID:

8671118

Promoter ID:

EPDNEW_M13589

Type:

initiation region

Name:

Dync1li1_1

Description:

Mus musculus dynein cytoplasmic 1 light intermediate chain 1, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	114,688,790 - 114,688,850	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2135610	AgrOrtholog
Ensembl Genes	ENSMUSG00000032435	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000047404	ENTREZGENE
	ENSMUST00000047404.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
InterPro	Dynein1_light_intermed_chain	UniProtKB/Swiss-Prot
	Dynein_light_int_chain	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
KEGG Report	mmu:235661	UniProtKB/Swiss-Prot
MGD	MGI:2135610	ENTREZGENE
NCBI Gene	Dync1li1	ENTREZGENE
PANTHER	CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 1	UniProtKB/Swiss-Prot
	PTHR12688	UniProtKB/Swiss-Prot
Pfam	DLIC	UniProtKB/Swiss-Prot
PhenoGen	Dync1li1	PhenoGen
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A2VDF8_MOUSE	UniProtKB/TrEMBL
	DC1L1_MOUSE	UniProtKB/Swiss-Prot
	Q3TVT4_MOUSE	UniProtKB/TrEMBL
	Q3TWG5	ENTREZGENE, UniProtKB/TrEMBL
	Q8R1Q8	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Dync1li1	dynein cytoplasmic 1 light intermediate chain 1	Dnclic1	dynein, cytoplasmic, light intermediate chain 1	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	Dnclic1	dynein, cytoplasmic, light intermediate chain 1	Dync1li1	dynein cytoplasmic 1 light intermediate chain 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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RGD Manual Annotations

Imported Annotations - KEGG (archival)

Mammalian Phenotype