Shank2 (SH3 and multiple ankyrin repeat domains 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Shank2 (SH3 and multiple ankyrin repeat domains 2) Mus musculus
Analyze
Symbol: Shank2
Name: SH3 and multiple ankyrin repeat domains 2
RGD ID: 736233
MGI Page MGI
Description: Enables ionotropic glutamate receptor binding activity. Involved in several processes, including learning or memory; modulation of chemical synaptic transmission; and social behavior. Located in several cellular components, including dendritic spine; photoreceptor inner segment; and photoreceptor outer segment. Colocalizes with neurofilament and postsynaptic membrane. Is expressed in cerebellum; cerebral cortex; frontal cortex; neocortex; and neocortex region. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SHANK2 (SH3 and multiple ankyrin repeat domains 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cortactin-binding protein 1; cortBP1; KIAA1022; mKIAA1022; P; ProSAP1; SH3 and multiple ankyrin repeat domains protein 2; SH3/ankyrin domain gene 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,531,819 - 143,979,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,555,665 - 143,978,231 (+)EnsemblGRCm39 Ensembl
GRCm387143,978,077 - 144,426,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,001,928 - 144,424,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv377151,361,425 - 151,608,580 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,840,654 - 144,232,065 (+)NCBIMGSCv36mm8
Celera7143,939,514 - 144,185,177 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(S)-colchicine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylparaben  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
enzacamene  (ISO)
epoxiconazole  (EXP,ISO)
ethanol  (EXP)
fenvalerate  (ISO)
fipronil  (ISO)
fumonisin B1  (ISO)
gabapentin  (ISO)
GW 4064  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
imipramine  (ISO)
lead(0)  (ISO)
linuron  (ISO)
lithium chloride  (ISO)
melphalan  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-D-aspartic acid  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitroglycerin  (ISO)
NMN zwitterion  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium atom  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
propanal  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sulfadiazine  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism. Modi ME, etal., Front Mol Neurosci. 2018 Jun 19;11:107. doi: 10.3389/fnmol.2018.00107. eCollection 2018.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9742101   PMID:10349636   PMID:10862698   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:14610273   PMID:14622142   PMID:14679199   PMID:15207857   PMID:16141072  
PMID:16141073   PMID:16452087   PMID:16452088   PMID:16606358   PMID:17114649   PMID:19208628   PMID:19299912   PMID:20800661   PMID:21119615   PMID:21267068   PMID:21795692   PMID:21873635  
PMID:22699619   PMID:22699620   PMID:23583105   PMID:23994547   PMID:24445315   PMID:24751538   PMID:25917711   PMID:25981743   PMID:26333830   PMID:26403076   PMID:26627310   PMID:27050589  
PMID:27145803   PMID:27199660   PMID:27507650   PMID:27544825   PMID:27581745   PMID:27779093   PMID:27903723   PMID:28326932   PMID:28484738   PMID:28671696   PMID:28706196   PMID:29046483  
PMID:29572432   PMID:29970987   PMID:29970989   PMID:30023428   PMID:30104731   PMID:30319350   PMID:30337855   PMID:30466882   PMID:30995482   PMID:31052177   PMID:31727973   PMID:31990031  
PMID:32252796   PMID:32325033   PMID:32640229   PMID:33126897   PMID:33347690   PMID:33491217   PMID:34177464   PMID:34433814   PMID:34594187   PMID:34741005   PMID:34899182   PMID:36100669  
PMID:36192805   PMID:36311025   PMID:36417873   PMID:36604605   PMID:36845137   PMID:37061705   PMID:37142655   PMID:37815916   PMID:38355793   PMID:38369099   PMID:38704506   PMID:39032541  


Genomics

Comparative Map Data
Shank2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397143,531,819 - 143,979,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7143,555,665 - 143,978,231 (+)EnsemblGRCm39 Ensembl
GRCm387143,978,077 - 144,426,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7144,001,928 - 144,424,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv377151,361,425 - 151,608,580 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367143,840,654 - 144,232,065 (+)NCBIMGSCv36mm8
Celera7143,939,514 - 144,185,177 (+)NCBICelera
Cytogenetic Map7F5NCBI
cM Map788.45NCBI
SHANK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381170,467,854 - 71,253,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1170,467,854 - 71,252,577 (-)EnsemblGRCh38hg38GRCh38
GRCh371170,313,959 - 70,963,623 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361169,991,609 - 70,185,520 (-)NCBINCBI36Build 36hg18NCBI36
Build 341170,012,765 - 70,185,520NCBI
Celera1167,575,145 - 68,227,408 (-)NCBICelera
Cytogenetic Map11q13.3-q13.4NCBI
HuRef1166,575,130 - 67,004,438 (-)NCBIHuRef
HuRef1167,062,872 - 67,229,732 (-)NCBIHuRef
CHM1_11170,197,402 - 70,819,749 (-)NCBICHM1_1
T2T-CHM13v2.01170,488,279 - 71,179,617 (-)NCBIT2T-CHM13v2.0
Shank2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81208,575,144 - 209,020,300 (+)NCBIGRCr8
mRatBN7.21199,146,210 - 199,590,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1199,169,429 - 199,589,394 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1207,554,601 - 207,972,754 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01214,636,692 - 215,056,974 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01207,310,858 - 207,731,152 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01217,149,156 - 217,593,950 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1217,151,166 - 217,592,763 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,028,791 - 224,450,737 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01222,118,530 - 222,150,341 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,399,856 - 204,855,474 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11204,553,308 - 205,005,561 (+)NCBI
Celera1196,732,183 - 197,149,084 (+)NCBICelera
Cytogenetic Map1q42NCBI
Shank2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542215,295,772 - 15,814,711 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542215,295,800 - 15,818,067 (+)NCBIChiLan1.0ChiLan1.0
SHANK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2971,441,934 - 72,138,948 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11172,486,126 - 73,180,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01165,570,677 - 66,268,139 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11168,857,186 - 69,495,237 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1168,860,606 - 69,437,925 (-)Ensemblpanpan1.1panPan2
SHANK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11847,477,625 - 47,915,557 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1847,635,788 - 47,912,117 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1846,010,915 - 46,522,454 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01848,113,005 - 48,589,823 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1848,098,110 - 48,589,819 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11847,525,882 - 48,036,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01847,111,601 - 47,622,440 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01847,858,659 - 48,368,562 (+)NCBIUU_Cfam_GSD_1.0
Shank2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049473,637,810 - 4,021,398 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936599217,138 - 463,771 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936599196,512 - 463,749 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHANK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl22,864,331 - 3,015,314 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.122,517,853 - 3,016,959 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22924,313 - 1,073,976 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SHANK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.113,453,268 - 4,104,515 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038100,644,177 - 101,362,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Shank2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476716,380,751 - 16,823,577 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476716,296,053 - 16,828,714 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4207
Count of miRNA genes:728
Interacting mature miRNAs:954
Transcripts:ENSMUST00000097929, ENSMUST00000105900, ENSMUST00000105902, ENSMUST00000136979, ENSMUST00000146006
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse

Markers in Region
Shank2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F5UniSTS
cM Map7 UniSTS
D7Mit177  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,061,043 - 144,061,182UniSTSGRCm38
MGSCv377151,246,948 - 151,247,087UniSTSGRCm37
Cytogenetic Map7F5UniSTS
cM Map772.0UniSTS
Whitehead Genetic767.8UniSTS
Whitehead/MRC_RH71454.83UniSTS
D7Mit47  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,338,215 - 144,338,424UniSTSGRCm38
MGSCv377151,524,120 - 151,524,329UniSTSGRCm37
Celera7144,100,807 - 144,101,016UniSTS
Cytogenetic Map7F5UniSTS
cM Map772.4UniSTS
Whitehead Genetic767.8UniSTS
Whitehead_YAC7 UniSTS
RH138116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,175,179 - 144,175,319UniSTSGRCm38
MGSCv377151,361,084 - 151,361,224UniSTSGRCm37
Celera7143,939,173 - 143,939,313UniSTS
Cytogenetic Map7F5UniSTS
D7Mit15  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387144,214,685 - 144,214,825UniSTSGRCm38
MGSCv377151,400,590 - 151,400,730UniSTSGRCm37
Celera7143,978,703 - 143,978,843UniSTS
Cytogenetic Map7F5UniSTS
cM Map771.0UniSTS
Whitehead Genetic766.7UniSTS
Whitehead/MRC_RH71460.17UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001113373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017322092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB099695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC124520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC127546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC140268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC152166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF540072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ109874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000097929   ⟹   ENSMUSP00000095542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,838,282 - 143,975,098 (+)Ensembl
GRCm38.p6 Ensembl7144,284,545 - 144,421,361 (+)Ensembl
Ensembl Acc Id: ENSMUST00000105900   ⟹   ENSMUSP00000101520
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,729,266 - 143,978,231 (+)Ensembl
GRCm38.p6 Ensembl7144,175,529 - 144,424,494 (+)Ensembl
Ensembl Acc Id: ENSMUST00000105902   ⟹   ENSMUSP00000101522
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,555,665 - 143,978,231 (+)Ensembl
GRCm38.p6 Ensembl7144,001,928 - 144,424,494 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136979
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,971,562 - 143,974,401 (+)Ensembl
GRCm38.p6 Ensembl7144,417,825 - 144,420,664 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146006   ⟹   ENSMUSP00000146440
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,838,176 - 143,978,219 (+)Ensembl
GRCm38.p6 Ensembl7144,284,439 - 144,424,482 (+)Ensembl
Ensembl Acc Id: ENSMUST00000213146   ⟹   ENSMUSP00000149134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,585,001 - 143,950,168 (+)Ensembl
GRCm38.p6 Ensembl7144,031,264 - 144,396,431 (+)Ensembl
Ensembl Acc Id: ENSMUST00000239495   ⟹   ENSMUSP00000159313
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7143,792,462 - 143,975,328 (+)Ensembl
GRCm38.p6 Ensembl7144,238,725 - 144,421,591 (+)Ensembl
RefSeq Acc Id: NM_001081370   ⟹   NP_001074839
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,838,131 - 143,978,231 (+)NCBI
GRCm387144,284,394 - 144,424,494 (+)NCBI
MGSCv377151,361,425 - 151,608,580 (+)RGD
Celera7143,939,514 - 144,185,177 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001113373   ⟹   NP_001106844
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,729,197 - 143,978,231 (+)NCBI
GRCm387144,175,460 - 144,424,494 (+)NCBI
MGSCv377151,361,425 - 151,608,580 (+)RGD
Celera7143,939,514 - 144,185,177 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006508519   ⟹   XP_006508582
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,627 - 143,979,780 (+)NCBI
GRCm387143,978,878 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508520   ⟹   XP_006508583
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,531,819 - 143,979,780 (+)NCBI
GRCm387143,978,077 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508521   ⟹   XP_006508584
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,531,819 - 143,979,780 (+)NCBI
GRCm387143,978,077 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508522   ⟹   XP_006508585
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,627 - 143,979,780 (+)NCBI
GRCm387143,978,878 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508523   ⟹   XP_006508586
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,627 - 143,979,780 (+)NCBI
GRCm387143,978,880 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508524   ⟹   XP_006508587
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,627 - 143,979,780 (+)NCBI
GRCm387143,978,878 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508525   ⟹   XP_006508588
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,626 - 143,979,780 (+)NCBI
GRCm387143,978,878 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508526   ⟹   XP_006508589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,626 - 143,979,780 (+)NCBI
GRCm387143,978,877 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508527   ⟹   XP_006508590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,627 - 143,979,780 (+)NCBI
GRCm387143,978,879 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508528   ⟹   XP_006508591
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,628 - 143,979,780 (+)NCBI
GRCm387143,978,880 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508529   ⟹   XP_006508592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,626 - 143,979,780 (+)NCBI
GRCm387143,978,878 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508530   ⟹   XP_006508593
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,630 - 143,979,780 (+)NCBI
GRCm387143,978,886 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508531   ⟹   XP_006508594
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,631 - 143,979,780 (+)NCBI
GRCm387143,978,886 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508532   ⟹   XP_006508595
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,631 - 143,979,780 (+)NCBI
GRCm387143,978,887 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508533   ⟹   XP_006508596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,723,987 - 143,979,780 (+)NCBI
GRCm387144,170,510 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508534   ⟹   XP_006508597
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,686,236 - 143,979,780 (+)NCBI
GRCm387144,132,486 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508535   ⟹   XP_006508598
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,792,428 - 143,979,780 (+)NCBI
GRCm387144,238,691 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006508536   ⟹   XP_006508599
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,834,291 - 143,979,780 (+)NCBI
GRCm387144,280,554 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322091   ⟹   XP_017177580
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,625 - 143,979,780 (+)NCBI
GRCm387143,978,874 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017322092   ⟹   XP_017177581
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,625 - 143,979,780 (+)NCBI
GRCm387143,978,874 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242322   ⟹   XP_030098182
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,531,820 - 143,979,780 (+)NCBI
GRCm387143,978,078 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242323   ⟹   XP_030098183
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,531,820 - 143,979,780 (+)NCBI
GRCm387143,978,078 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242325   ⟹   XP_030098185
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,723,987 - 143,979,780 (+)NCBI
GRCm387144,170,510 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242326   ⟹   XP_030098186
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,834,290 - 143,979,780 (+)NCBI
GRCm387144,280,553 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242327   ⟹   XP_030098187
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,793,522 - 143,979,780 (+)NCBI
GRCm387144,239,785 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242328   ⟹   XP_030098188
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,837,851 - 143,979,780 (+)NCBI
GRCm387144,284,114 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242329   ⟹   XP_030098189
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,837,851 - 143,979,780 (+)NCBI
GRCm387144,284,114 - 144,426,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152869   ⟹   XP_036008762
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,792,428 - 143,979,780 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152870   ⟹   XP_036008763
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,838,626 - 143,979,780 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152871   ⟹   XP_036008764
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,837,851 - 143,979,780 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934050
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,551 - 143,974,664 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934051
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397143,532,362 - 143,965,268 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001074839 (Get FASTA)   NCBI Sequence Viewer  
  NP_001106844 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508582 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508583 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508584 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508585 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508586 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508587 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508588 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508589 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508590 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508591 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508592 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508593 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508594 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508595 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508596 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508597 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508598 (Get FASTA)   NCBI Sequence Viewer  
  XP_006508599 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177580 (Get FASTA)   NCBI Sequence Viewer  
  XP_017177581 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098182 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098183 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098185 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098186 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098187 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098188 (Get FASTA)   NCBI Sequence Viewer  
  XP_030098189 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008762 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008763 (Get FASTA)   NCBI Sequence Viewer  
  XP_036008764 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAC58120 (Get FASTA)   NCBI Sequence Viewer  
  BAD90424 (Get FASTA)   NCBI Sequence Viewer  
  BAE23976 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000095542.4
  ENSMUSP00000101520
  ENSMUSP00000101520.3
  ENSMUSP00000101522
  ENSMUSP00000101522.2
  ENSMUSP00000146440
  ENSMUSP00000146440.2
  ENSMUSP00000149134.2
  ENSMUSP00000159313
  ENSMUSP00000159313.2
GenBank Protein Q80Z38 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001074839   ⟸   NM_001081370
- Peptide Label: isoform a
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106844   ⟸   NM_001113373
- Peptide Label: isoform b
- UniProtKB: A0A6I8MWY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508583   ⟸   XM_006508520
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006508584   ⟸   XM_006508521
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006508582   ⟸   XM_006508519
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006508588   ⟸   XM_006508525
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006508589   ⟸   XM_006508526
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006508592   ⟸   XM_006508529
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006508587   ⟸   XM_006508524
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006508585   ⟸   XM_006508522
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006508586   ⟸   XM_006508523
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006508590   ⟸   XM_006508527
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006508591   ⟸   XM_006508528
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006508593   ⟸   XM_006508530
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_006508594   ⟸   XM_006508531
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_006508595   ⟸   XM_006508532
- Peptide Label: isoform X13
- UniProtKB: D3Z5K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508597   ⟸   XM_006508534
- Peptide Label: isoform X15
- UniProtKB: A0A6I8MWY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508596   ⟸   XM_006508533
- Peptide Label: isoform X14
- UniProtKB: Q3UTK4 (UniProtKB/Swiss-Prot),   E9QPH7 (UniProtKB/Swiss-Prot),   Q5DU07 (UniProtKB/Swiss-Prot),   Q80Z38 (UniProtKB/Swiss-Prot),   A0A6I8MWY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508598   ⟸   XM_006508535
- Peptide Label: isoform X17
- UniProtKB: A0A6I8MWY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508599   ⟸   XM_006508536
- Peptide Label: isoform X19
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017177581   ⟸   XM_017322092
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017177580   ⟸   XM_017322091
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_030098183   ⟸   XM_030242323
- Peptide Label: isoform X11
RefSeq Acc Id: XP_030098182   ⟸   XM_030242322
- Peptide Label: isoform X11
RefSeq Acc Id: XP_030098185   ⟸   XM_030242325
- Peptide Label: isoform X16
- UniProtKB: A0A6I8MWY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098187   ⟸   XM_030242327
- Peptide Label: isoform X19
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098186   ⟸   XM_030242326
- Peptide Label: isoform X18
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098188   ⟸   XM_030242328
- Peptide Label: isoform X20
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098189   ⟸   XM_030242329
- Peptide Label: isoform X21
- UniProtKB: A0A1C7ZMY3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000101520   ⟸   ENSMUST00000105900
Ensembl Acc Id: ENSMUSP00000101522   ⟸   ENSMUST00000105902
Ensembl Acc Id: ENSMUSP00000159313   ⟸   ENSMUST00000239495
Ensembl Acc Id: ENSMUSP00000146440   ⟸   ENSMUST00000146006
Ensembl Acc Id: ENSMUSP00000149134   ⟸   ENSMUST00000213146
Ensembl Acc Id: ENSMUSP00000095542   ⟸   ENSMUST00000097929
RefSeq Acc Id: XP_036008762   ⟸   XM_036152869
- Peptide Label: isoform X22
RefSeq Acc Id: XP_036008764   ⟸   XM_036152871
- Peptide Label: isoform X22
RefSeq Acc Id: XP_036008763   ⟸   XM_036152870
- Peptide Label: isoform X22
Protein Domains
PDZ   SAM   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80Z38-F1-model_v2 AlphaFold Q80Z38 1-1476 view protein structure

Promoters
RGD ID:8666277
Promoter ID:EPDNEW_M11170
Type:initiation region
Name:Shank2_2
Description:Mus musculus SH3 and multiple ankyrin repeat domains 2 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170