Macroh2a1 (macroH2A.1 histone) - Rat Genome Database

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Gene: Macroh2a1 (macroH2A.1 histone) Mus musculus
Analyze
Symbol: Macroh2a1
Name: macroH2A.1 histone
RGD ID: 736206
MGI Page MGI
Description: Enables ADP-D-ribose binding activity; ADP-D-ribose modification-dependent protein binding activity; and chromatin binding activity. Involved in regulation of nucleobase-containing compound metabolic process; regulation of oxidative phosphorylation; and regulation of response to oxidative stress. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in condensed chromosome. Is active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study myelodysplastic syndrome. Orthologous to human MACROH2A1 (macroH2A.1 histone).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: core histone macro-H2A.1; H2A histone family, member Y; H2A.y; H2A/y; H2af; H2AF12; H2AF12M; H2afy; histone macroH2A1; MACROH2; macroH2A1.2; mH2a; mH2a1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,221,435 - 56,283,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,221,432 - 56,284,174 (-)EnsemblGRCm39 Ensembl
GRCm381356,073,622 - 56,135,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,073,619 - 56,136,361 (-)EnsemblGRCm38mm10GRCm38
MGSCv371356,174,983 - 56,236,911 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361356,083,796 - 56,145,137 (-)NCBIMGSCv36mm8
Celera1357,128,470 - 57,190,557 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlormequat chloride  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
clomipramine  (ISO)
dexamethasone  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
fenthion  (EXP)
finasteride  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
hydroquinone  (ISO)
imipramine  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
mercury dibromide  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (EXP)
pirinixic acid  (EXP)
propiconazole  (EXP,ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sulfadimethoxine  (ISO)
sulindac  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Histone variants: dynamic punctuation in transcription. Weber CM and Henikoff S, Genes Dev. 2014 Apr 1;28(7):672-82. doi: 10.1101/gad.238873.114.
Additional References at PubMed
PMID:8889548   PMID:9634239   PMID:10349636   PMID:10471737   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11262398   PMID:11331621   PMID:12082075   PMID:12183056   PMID:12419249  
PMID:12477932   PMID:14610273   PMID:14611647   PMID:14676273   PMID:14681479   PMID:15489334   PMID:15564378   PMID:15680357   PMID:15782199   PMID:16107708   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:16738309   PMID:17242180   PMID:18195046   PMID:18799693   PMID:18936163   PMID:19075228   PMID:19799774   PMID:20132012   PMID:20359320   PMID:20937776   PMID:20943707  
PMID:21072209   PMID:21179167   PMID:21267068   PMID:21364955   PMID:21552206   PMID:21677750   PMID:21738686   PMID:21873635   PMID:21969577   PMID:22331466   PMID:23022728   PMID:23077180  
PMID:23372727   PMID:23463008   PMID:24071584   PMID:25119498   PMID:25312643   PMID:25526730   PMID:25703348   PMID:25731851   PMID:25737280   PMID:25818643   PMID:26300260   PMID:26772755  
PMID:26832413   PMID:28378742   PMID:28634551   PMID:28671696   PMID:28934364   PMID:28991266   PMID:29559679   PMID:30595499   PMID:31040226   PMID:31439048   PMID:32325033   PMID:32365743  
PMID:32649884   PMID:33159050   PMID:34046991   PMID:34161765   PMID:34320234   PMID:34469727   PMID:35590030   PMID:36069228   PMID:36417873   PMID:37605008   PMID:37926763  


Genomics

Comparative Map Data
Macroh2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391356,221,435 - 56,283,439 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1356,221,432 - 56,284,174 (-)EnsemblGRCm39 Ensembl
GRCm381356,073,622 - 56,135,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1356,073,619 - 56,136,361 (-)EnsemblGRCm38mm10GRCm38
MGSCv371356,174,983 - 56,236,911 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361356,083,796 - 56,145,137 (-)NCBIMGSCv36mm8
Celera1357,128,470 - 57,190,557 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
MACROH2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385135,334,381 - 135,399,887 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5135,334,381 - 135,399,914 (-)EnsemblGRCh38hg38GRCh38
GRCh375134,670,071 - 134,735,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,697,970 - 134,763,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 345134,697,969 - 134,762,802NCBI
Celera5130,793,877 - 130,859,396 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,857,754 - 129,923,276 (-)NCBIHuRef
CHM1_15134,102,741 - 134,168,247 (-)NCBICHM1_1
T2T-CHM13v2.05135,861,569 - 135,927,059 (-)NCBIT2T-CHM13v2.0
Macroh2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,484,340 - 8,547,268 (+)NCBIGRCr8
mRatBN7.2178,479,331 - 8,542,071 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,479,372 - 8,542,072 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,494,921 - 8,557,042 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,028,056 - 10,089,627 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,491,302 - 8,553,426 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,282,109 - 9,344,698 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,282,675 - 9,344,678 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,440,567 - 11,502,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41714,457,307 - 14,520,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11714,457,306 - 14,520,963 (+)NCBI
Celera178,563,234 - 8,625,826 (+)NCBICelera
Cytogenetic Map17p14NCBI
LOC102008188
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540830,497,531 - 30,550,118 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540830,497,531 - 30,550,095 (-)NCBIChiLan1.0ChiLan1.0
LOC100974858
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24130,622,460 - 130,690,055 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,762,020 - 128,826,904 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,727,065 - 130,791,932 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,868,521 - 136,933,834 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,868,521 - 136,933,834 (-)Ensemblpanpan1.1panPan2
MACROH2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11123,369,957 - 23,448,235 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1123,370,300 - 23,438,219 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1122,118,904 - 22,197,335 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01124,196,790 - 24,265,246 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1124,205,586 - 24,264,536 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,875,051 - 22,953,381 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,740,600 - 22,819,048 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01123,384,272 - 23,469,034 (-)NCBIUU_Cfam_GSD_1.0
LOC101971629
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,471,582 - 123,531,449 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,495,862 - 2,556,603 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,496,489 - 2,556,352 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MACROH2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2137,534,138 - 137,623,886 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12137,535,128 - 137,623,886 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22143,054,432 - 143,135,657 (-)NCBISscrofa10.2Sscrofa10.2susScr3
H2AFY
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12338,113,212 - 38,178,227 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2338,113,195 - 38,168,382 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603439,737,224 - 39,802,999 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101706296
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473311,650,537 - 11,715,999 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473311,650,067 - 11,714,399 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Macroh2a1
2125 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1251
Count of miRNA genes:490
Interacting mature miRNAs:598
Transcripts:ENSMUST00000016081, ENSMUST00000045788, ENSMUST00000137835, ENSMUST00000139511, ENSMUST00000141031, ENSMUST00000141589, ENSMUST00000154564, ENSMUST00000154778
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse

Markers in Region
D13Mit113  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381356,127,983 - 56,128,131UniSTSGRCm38
MGSCv371356,229,344 - 56,229,492UniSTSGRCm37
Celera1357,183,040 - 57,183,188UniSTS
Cytogenetic Map13B2UniSTS
cM Map1335.0UniSTS
Whitehead Genetic1321.9UniSTS
Whitehead_YAC13 UniSTS
H2afy  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13B2UniSTS
cM Map1330.06UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_382440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB071988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF123312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF171080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF171081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW990415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB633156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC006955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE988321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB574813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ095488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV561613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000016081   ⟹   ENSMUSP00000016081
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,221,432 - 56,283,444 (-)Ensembl
GRCm38.p6 Ensembl1356,073,619 - 56,135,631 (-)Ensembl
RefSeq Acc Id: ENSMUST00000045788   ⟹   ENSMUSP00000038221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,221,435 - 56,283,343 (-)Ensembl
GRCm38.p6 Ensembl1356,073,622 - 56,135,530 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,221,979 - 56,232,334 (-)Ensembl
GRCm38.p6 Ensembl1356,074,166 - 56,084,521 (-)Ensembl
RefSeq Acc Id: ENSMUST00000139511
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,243,369 - 56,283,343 (-)Ensembl
GRCm38.p6 Ensembl1356,095,556 - 56,135,530 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141031
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,248,702 - 56,283,253 (-)Ensembl
GRCm38.p6 Ensembl1356,100,889 - 56,135,440 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,222,172 - 56,237,871 (-)Ensembl
GRCm38.p6 Ensembl1356,074,359 - 56,090,058 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154564
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,252,254 - 56,282,638 (-)Ensembl
GRCm38.p6 Ensembl1356,104,441 - 56,134,825 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154778
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1356,252,243 - 56,284,174 (-)Ensembl
GRCm38.p6 Ensembl1356,104,430 - 56,136,361 (-)Ensembl
RefSeq Acc Id: NM_001159513   ⟹   NP_001152985
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,363 (-)NCBI
GRCm381356,073,622 - 56,135,550 (-)NCBI
MGSCv371356,174,983 - 56,236,911 (-)RGD
Celera1357,128,470 - 57,190,557 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159514   ⟹   NP_001152986
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,363 (-)NCBI
GRCm381356,073,622 - 56,135,550 (-)NCBI
MGSCv371356,174,983 - 56,236,911 (-)RGD
Celera1357,128,470 - 57,190,557 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159515   ⟹   NP_001152987
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,363 (-)NCBI
GRCm381356,073,622 - 56,135,550 (-)NCBI
MGSCv371356,174,983 - 56,236,911 (-)RGD
Celera1357,128,470 - 57,190,557 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_012015   ⟹   NP_036145
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,363 (-)NCBI
GRCm381356,073,622 - 56,135,550 (-)NCBI
MGSCv371356,174,983 - 56,236,911 (-)RGD
Celera1357,128,470 - 57,190,557 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517257   ⟹   XP_006517320
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,238,492 - 56,283,439 (-)NCBI
GRCm381356,090,679 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517258   ⟹   XP_006517321
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,238,492 - 56,283,439 (-)NCBI
GRCm381356,090,679 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780784
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780785
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780786
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950455
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950456
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950457
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950458
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: XR_382440
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391356,221,435 - 56,283,439 (-)NCBI
GRCm381356,073,622 - 56,135,626 (-)NCBI
Sequence:
RefSeq Acc Id: NP_036145   ⟸   NM_012015
- Peptide Label: isoform 1
- UniProtKB: Q9QZQ8 (UniProtKB/Swiss-Prot),   Q9CTH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152985   ⟸   NM_001159513
- Peptide Label: isoform 2
- UniProtKB: Q9QZQ8 (UniProtKB/Swiss-Prot),   Q9CTH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001152986   ⟸   NM_001159514
- Peptide Label: isoform 3
- UniProtKB: Q91VZ2 (UniProtKB/Swiss-Prot),   Q9QZQ7 (UniProtKB/Swiss-Prot),   Q9QZQ8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001152987   ⟸   NM_001159515
- Peptide Label: isoform 4
- UniProtKB: Q9QZQ8 (UniProtKB/Swiss-Prot),   Q9CTH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517321   ⟸   XM_006517258
- Peptide Label: isoform X2
- UniProtKB: Q8CA90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517320   ⟸   XM_006517257
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000038221   ⟸   ENSMUST00000045788
RefSeq Acc Id: ENSMUSP00000016081   ⟸   ENSMUST00000016081
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZQ8-F1-model_v2 AlphaFold Q9QZQ8 1-372 view protein structure

Promoters
RGD ID:8680490
Promoter ID:EPDNEW_M18276
Type:initiation region
Name:H2afy_1
Description:Mus musculus H2A histone family, member Y , transcript variant4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381356,135,495 - 56,135,555EPDNEW
RGD ID:6824004
Promoter ID:MM_KWN:14270
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Lung
Transcripts:OTTMUST00000049553
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361356,185,396 - 56,185,896 (-)MPROMDB
RGD ID:6824003
Promoter ID:MM_KWN:14271
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   Lung
Transcripts:OTTMUST00000049552
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361356,191,274 - 56,191,774 (-)MPROMDB
RGD ID:6824005
Promoter ID:MM_KWN:14273
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B6,   Spleen
Transcripts:NM_001159513,   NM_001159515,   OTTMUST00000049546,   OTTMUST00000049547,   OTTMUST00000049548,   OTTMUST00000049550,   UC007QSI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361356,236,666 - 56,237,166 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349392 AgrOrtholog
Ensembl Genes ENSMUSG00000015937 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000016081 ENTREZGENE
  ENSMUST00000016081.13 UniProtKB/Swiss-Prot
  ENSMUST00000045788 ENTREZGENE
  ENSMUST00000045788.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.220.10 UniProtKB/Swiss-Prot
InterPro Core_histone_macro-H2A UniProtKB/Swiss-Prot
  Histone-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A/H2B/H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Macro_dom UniProtKB/Swiss-Prot
  Macro_dom-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Macro_H2A UniProtKB/Swiss-Prot
KEGG Report mmu:26914 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1349392 ENTREZGENE
NCBI Gene 26914 ENTREZGENE
PANTHER CORE HISTONE MACRO-H2A.1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23430 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Histone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Histone_H2A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Macro UniProtKB/Swiss-Prot
PhenoGen Macroh2a1 PhenoGen
PIRSF Core_histone_macro-H2A UniProtKB/Swiss-Prot
PRINTS HISTONEH2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MACRO UniProtKB/Swiss-Prot
SMART A1pp UniProtKB/Swiss-Prot
  H2A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47113 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52949 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt H2AY_MOUSE UniProtKB/Swiss-Prot
  Q8CA90 ENTREZGENE, UniProtKB/TrEMBL
  Q91VZ2 ENTREZGENE
  Q9CTH9 ENTREZGENE, UniProtKB/TrEMBL
  Q9QZQ7 ENTREZGENE
  Q9QZQ8 ENTREZGENE
UniProt Secondary Q91VZ2 UniProtKB/Swiss-Prot
  Q9QZQ7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-13 Macroh2a1  macroH2A.1 histone  H2afy  H2A histone family, member Y  Symbol and/or name change 5135510 APPROVED