Scn10a (sodium channel, voltage-gated, type X, alpha) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Scn10a (sodium channel, voltage-gated, type X, alpha) Mus musculus
Analyze
Symbol: Scn10a
Name: sodium channel, voltage-gated, type X, alpha
RGD ID: 736179
MGI Page MGI
Description: Enables voltage-gated sodium channel activity. Involved in behavioral response to pain; circadian rhythm; and detection of stimulus involved in sensory perception. Acts upstream of or within several processes, including cardiac conduction; regulation of atrial cardiac muscle cell membrane depolarization; and sodium ion transport. Located in C-fiber and plasma membrane. Is expressed in brain; ganglia; and heart. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 2. Orthologous to human SCN10A (sodium voltage-gated channel alpha subunit 10).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Nav; Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; SNS; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; voltage gated sodium channel; voltage-gated sodium channel Nav1.8 variant a; voltage-gated sodium channel Nav1.8 variant b; voltage-gated sodium channel subunit alpha Nav1.8
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,437,522 - 119,548,388 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,437,522 - 119,548,388 (-)EnsemblGRCm39 Ensembl
GRCm389119,608,456 - 119,719,322 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,608,456 - 119,719,322 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,517,584 - 119,603,478 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369119,457,165 - 119,543,058 (-)NCBIMGSCv36mm8
Celera9120,082,167 - 120,168,344 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
alfentanil pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lidocaine pharmacokinetics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models. Joshi SK, etal., J Pain. 2009 Mar;10(3):306-15. Epub 2008 Dec 13.
2. Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse. Kozak CA and Sangameswaran L, Mamm Genome 1996 Oct;7(10):787-8.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Relationship of axonal voltage-gated sodium channel 1.8 (NaV1.8) mRNA accumulation to sciatic nerve injury-induced painful neuropathy in rats. Ruangsri S, etal., J Biol Chem. 2011 Nov 18;286(46):39836-47. Epub 2011 Sep 30.
Additional References at PubMed
PMID:9143495   PMID:9148921   PMID:10349636   PMID:10398684   PMID:10448219   PMID:10938298   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11495938   PMID:11568640   PMID:12351708  
PMID:12824446   PMID:14533785   PMID:15047701   PMID:15123669   PMID:15205116   PMID:15314237   PMID:15621361   PMID:15979214   PMID:16029194   PMID:16111501   PMID:16141072   PMID:16141073  
PMID:16413788   PMID:16446141   PMID:16478543   PMID:16602821   PMID:16850455   PMID:16857712   PMID:16985003   PMID:17035534   PMID:17052333   PMID:17350991   PMID:17540018   PMID:17568746  
PMID:18399542   PMID:18466327   PMID:18498732   PMID:18498735   PMID:18669863   PMID:18845912   PMID:19239624   PMID:19535578   PMID:19931571   PMID:19953341   PMID:20062061   PMID:20147541  
PMID:20174994   PMID:20609517   PMID:20702715   PMID:20861385   PMID:21040852   PMID:21059214   PMID:21145890   PMID:21267068   PMID:21295407   PMID:21415372   PMID:21618224   PMID:21873635  
PMID:21903816   PMID:22087007   PMID:22260870   PMID:22367990   PMID:22426212   PMID:22449024   PMID:22531176   PMID:22703890   PMID:22706305   PMID:22723299   PMID:22723301   PMID:22850668  
PMID:22870919   PMID:22875917   PMID:23433317   PMID:23575686   PMID:23652591   PMID:23711479   PMID:23773488   PMID:23986244   PMID:24069332   PMID:24216512   PMID:24259584   PMID:24305821  
PMID:24440715   PMID:24447515   PMID:24642470   PMID:24759321   PMID:24763188   PMID:24903831   PMID:24952961   PMID:24957987   PMID:25101983   PMID:25116249   PMID:25161883   PMID:25369838  
PMID:25426020   PMID:25453842   PMID:25600872   PMID:25747279   PMID:25903105   PMID:25959819   PMID:26076474   PMID:26514267   PMID:26915043   PMID:26923409   PMID:26971948   PMID:27022626  
PMID:27068287   PMID:27161260   PMID:27215377   PMID:27566399   PMID:27604420   PMID:27708397   PMID:27806966   PMID:27822503   PMID:27916453   PMID:27984182   PMID:28074005   PMID:28280205  
PMID:28450535   PMID:28558976   PMID:28658621   PMID:28767511   PMID:28871176   PMID:29031710   PMID:29497094   PMID:29505031   PMID:29669290   PMID:29970412   PMID:29988128   PMID:30304667  
PMID:30395542   PMID:30459229   PMID:30617209   PMID:30714145   PMID:30755524   PMID:30826183   PMID:30843875   PMID:30886406   PMID:30907928   PMID:30917309   PMID:30930747   PMID:31197234  
PMID:31253755   PMID:31324538   PMID:31534133   PMID:31618460   PMID:31666509   PMID:31730854   PMID:32019828   PMID:32102913   PMID:32116538   PMID:32170060   PMID:32277850   PMID:32286429  
PMID:32325033   PMID:32418916   PMID:32441256   PMID:32641826   PMID:32687056   PMID:32691511   PMID:32750173   PMID:33057056   PMID:33098765   PMID:33318075   PMID:33333021   PMID:33515125  
PMID:33722956   PMID:33789102   PMID:33836560   PMID:33910361   PMID:33932866   PMID:34006861   PMID:34012116   PMID:34043943   PMID:34174335   PMID:34338291   PMID:34400519   PMID:34413846  
PMID:34544832   PMID:34580157   PMID:34585109   PMID:34782600   PMID:34784974   PMID:34787642   PMID:34921782   PMID:34925037   PMID:34931070   PMID:34991641   PMID:35065194   PMID:35233469  
PMID:35263589   PMID:35482870   PMID:35503781   PMID:35579957   PMID:35904071   PMID:36243004   PMID:36334588   PMID:36859544   PMID:36973009   PMID:36996219   PMID:37061508   PMID:37117223  
PMID:37120427   PMID:37699522   PMID:37845223   PMID:37995657   PMID:38025786   PMID:38040043   PMID:38124021   PMID:38167468   PMID:38172636   PMID:38388698   PMID:38538784   PMID:38561433  
PMID:38663398   PMID:38851191   PMID:38915692   PMID:39163201   PMID:39366945  


Genomics

Comparative Map Data
Scn10a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399119,437,522 - 119,548,388 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9119,437,522 - 119,548,388 (-)EnsemblGRCm39 Ensembl
GRCm389119,608,456 - 119,719,322 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,608,456 - 119,719,322 (-)EnsemblGRCm38mm10GRCm38
MGSCv379119,517,584 - 119,603,478 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369119,457,165 - 119,543,058 (-)NCBIMGSCv36mm8
Celera9120,082,167 - 120,168,344 (-)NCBICelera
Cytogenetic Map9F3NCBI
cM Map971.33NCBI
SCN10A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38338,696,807 - 38,816,217 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl338,696,802 - 38,816,286 (-)EnsemblGRCh38hg38GRCh38
GRCh37338,738,298 - 38,857,708 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,713,841 - 38,810,505 (-)NCBINCBI36Build 36hg18NCBI36
Build 34338,713,840 - 38,810,505NCBI
Celera338,677,898 - 38,774,543 (-)NCBICelera
Cytogenetic Map3p22.2NCBI
HuRef338,781,159 - 38,877,645 (-)NCBIHuRef
CHM1_1338,690,433 - 38,787,099 (-)NCBICHM1_1
T2T-CHM13v2.0338,709,028 - 38,828,431 (-)NCBIT2T-CHM13v2.0
Scn10a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,228,424 - 128,340,749 (-)NCBIGRCr8
mRatBN7.28119,350,723 - 119,462,882 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8119,350,724 - 119,462,614 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8124,932,439 - 125,044,084 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,131,466 - 123,243,120 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08120,965,215 - 121,076,407 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,298,593 - 128,416,896 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,298,594 - 128,416,650 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08127,503,061 - 127,620,197 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,578,222 - 124,690,458 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18124,597,959 - 124,710,195 (-)NCBI
Celera8118,500,856 - 118,611,564 (-)NCBICelera
Cytogenetic Map8q32NCBI
Scn10a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542725,157,179 - 25,243,473 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542725,157,179 - 25,244,020 (+)NCBIChiLan1.0ChiLan1.0
SCN10A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2238,649,419 - 38,747,494 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1338,654,181 - 38,752,256 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0338,593,765 - 38,691,172 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1338,876,068 - 38,972,247 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,876,068 - 38,972,247 (-)Ensemblpanpan1.1panPan2
SCN10A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1238,420,468 - 8,527,414 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl238,420,472 - 8,527,383 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,460,551 - 8,567,500 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0238,708,298 - 8,817,466 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl238,709,728 - 8,817,466 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1238,523,267 - 8,630,160 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,664,475 - 8,771,500 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0238,658,580 - 8,765,552 (-)NCBIUU_Cfam_GSD_1.0
Scn10a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118194,871,017 - 194,982,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,010,123 - 28,102,124 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,010,123 - 28,102,124 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCN10A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1323,481,255 - 23,570,379 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11323,481,537 - 23,570,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21325,726,454 - 25,805,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCN10A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.115624,962 - 724,018 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl15625,742 - 721,963 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660639,354,464 - 9,451,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scn10a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247312,254,445 - 2,355,738 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247312,254,445 - 2,356,174 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scn10a
3543 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:178
Count of miRNA genes:154
Interacting mature miRNAs:166
Transcripts:ENSMUST00000084787
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse

Markers in Region
UniSTS:236281  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389119,645,618 - 119,645,817UniSTSGRCm38
MGSCv379119,554,736 - 119,554,935UniSTSGRCm37
Celera9120,119,467 - 120,119,666UniSTS
Cytogenetic Map9F4UniSTS
cM Map967.0UniSTS
Y09108  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389119,608,631 - 119,608,741UniSTSGRCm38
MGSCv379119,517,749 - 119,517,859UniSTSGRCm37
Celera9120,082,332 - 120,082,442UniSTS
Cytogenetic Map9F4UniSTS
cM Map967.0UniSTS
Whitehead/MRC_RH91177.51UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001205321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017313223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC171201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ622906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ623269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ623270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY538273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ497421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ497422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ497423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ497424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ497425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ516971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM373697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KM373698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L42342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y09108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000084787   ⟹   ENSMUSP00000081845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9119,437,522 - 119,548,098 (-)Ensembl
GRCm38.p6 Ensembl9119,608,456 - 119,719,032 (-)Ensembl
Ensembl Acc Id: ENSMUST00000213392   ⟹   ENSMUSP00000148987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9119,437,533 - 119,548,388 (-)Ensembl
GRCm38.p6 Ensembl9119,608,467 - 119,719,322 (-)Ensembl
Ensembl Acc Id: ENSMUST00000213401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9119,523,389 - 119,548,029 (-)Ensembl
GRCm38.p6 Ensembl9119,694,323 - 119,718,963 (-)Ensembl
Ensembl Acc Id: ENSMUST00000214408   ⟹   ENSMUSP00000150830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9119,437,991 - 119,523,391 (-)Ensembl
GRCm38.p6 Ensembl9119,608,925 - 119,694,325 (-)Ensembl
Ensembl Acc Id: ENSMUST00000216583
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9119,476,191 - 119,517,105 (-)Ensembl
GRCm38.p6 Ensembl9119,647,125 - 119,688,039 (-)Ensembl
RefSeq Acc Id: NM_001205321   ⟹   NP_001192250
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,437,522 - 119,548,098 (-)NCBI
GRCm389119,608,456 - 119,719,032 (-)NCBI
Celera9120,082,157 - 120,189,198 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_009134   ⟹   NP_033160
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,437,522 - 119,548,098 (-)NCBI
GRCm389119,608,456 - 119,719,032 (-)NCBI
MGSCv379119,517,584 - 119,603,478 (-)RGD
Celera9120,082,157 - 120,189,198 (-)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017313221   ⟹   XP_017168710
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,445,853 - 119,548,388 (-)NCBI
GRCm389119,616,787 - 119,719,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313222   ⟹   XP_017168711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,458,447 - 119,548,388 (-)NCBI
GRCm389119,629,491 - 119,719,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017313223   ⟹   XP_017168712
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,437,532 - 119,548,388 (-)NCBI
GRCm389119,608,466 - 119,719,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036154738   ⟹   XP_036010631
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399119,457,608 - 119,548,388 (-)NCBI
Sequence:
RefSeq Acc Id: NP_033160   ⟸   NM_009134
- Peptide Label: isoform 2
- UniProtKB: A0A0R5RP33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001192250   ⟸   NM_001205321
- Peptide Label: isoform 1
- UniProtKB: K3W4P8 (UniProtKB/TrEMBL),   A0A0R5RP34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168712   ⟸   XM_017313223
- Peptide Label: isoform X4
- UniProtKB: Q6KCH7 (UniProtKB/Swiss-Prot),   Q6EWG7 (UniProtKB/Swiss-Prot),   Q62243 (UniProtKB/Swiss-Prot),   Q703F9 (UniProtKB/Swiss-Prot),   Q6QIY3 (UniProtKB/Swiss-Prot),   A0A0R5RP33 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017168710   ⟸   XM_017313221
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017168711   ⟸   XM_017313222
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSMUSP00000081845   ⟸   ENSMUST00000084787
Ensembl Acc Id: ENSMUSP00000148987   ⟸   ENSMUST00000213392
Ensembl Acc Id: ENSMUSP00000150830   ⟸   ENSMUST00000214408
RefSeq Acc Id: XP_036010631   ⟸   XM_036154738
- Peptide Label: isoform X3
Protein Domains
Ion transport   IQ   Sodium ion transport-associated

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6QIY3-F1-model_v2 AlphaFold Q6QIY3 1-1958 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108029 AgrOrtholog
Ensembl Genes ENSMUSG00000034533 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000084787 ENTREZGENE
  ENSMUST00000084787.6 UniProtKB/TrEMBL
  ENSMUST00000213392 ENTREZGENE
  ENSMUST00000213392.2 UniProtKB/Swiss-Prot
  ENSMUST00000214408.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  iswi atpase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na_channel_asu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na_chnl_inactivation_gate UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na_trans_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VGCC_Ca_Na UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20264 UniProtKB/Swiss-Prot
MGD MGI:108029 ENTREZGENE
NCBI Gene 20264 ENTREZGENE
PANTHER PTHR10037 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10037:SF208 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na_trans_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scn10a PhenoGen
PRINTS NACHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R5RP33 ENTREZGENE, UniProtKB/TrEMBL
  A0A0R5RP34 ENTREZGENE, UniProtKB/TrEMBL
  K3W4P8 ENTREZGENE, UniProtKB/TrEMBL
  P70276_MOUSE UniProtKB/TrEMBL
  Q62243 ENTREZGENE
  Q6EWG7 ENTREZGENE
  Q6KCH7 ENTREZGENE
  Q6QIY3 ENTREZGENE
  Q703F9 ENTREZGENE
  SCNAA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q62243 UniProtKB/Swiss-Prot
  Q6EWG7 UniProtKB/Swiss-Prot
  Q6KCH7 UniProtKB/Swiss-Prot
  Q703F9 UniProtKB/Swiss-Prot