DPP3 (dipeptidyl peptidase 3) - Rat Genome Database

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Gene: DPP3 (dipeptidyl peptidase 3) Homo sapiens
Analyze
Symbol: DPP3
Name: dipeptidyl peptidase 3
RGD ID: 736150
HGNC Page HGNC:3008
Description: Enables dipeptidyl-peptidase activity and zinc ion binding activity. Involved in proteolysis. Located in cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: dipeptidyl aminopeptidase III; dipeptidyl arylamidase III; dipeptidyl peptidase III; dipeptidylpeptidase 3; DPP III; DPPIII; enkephalinase B; FLJ11387; FLJ22331
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: DPP3P1   DPP3P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381166,480,434 - 66,509,657 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1166,480,013 - 66,509,657 (+)EnsemblGRCh38hg38GRCh38
GRCh371166,247,905 - 66,277,128 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,004,456 - 66,033,706 (+)NCBINCBI36Build 36hg18NCBI36
Build 341166,004,470 - 66,033,700NCBI
Celera1163,568,130 - 63,597,365 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1162,575,380 - 62,605,040 (+)NCBIHuRef
CHM1_11166,131,228 - 66,160,856 (+)NCBICHM1_1
T2T-CHM13v2.01166,476,691 - 66,505,896 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
cytosol  (IDA,IEA)
extracellular exosome  (HDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Hayes JD and Dinkova-Kostova AT, Trends Biochem Sci. 2014 Apr;39(4):199-218. doi: 10.1016/j.tibs.2014.02.002. Epub 2014 Mar 16.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:618680   PMID:2044841   PMID:2858361   PMID:2906822   PMID:3233187   PMID:3348886   PMID:3791505   PMID:6368131   PMID:7041700   PMID:7044004   PMID:8125298   PMID:9425109  
PMID:9640230   PMID:9711218   PMID:10387075   PMID:10773679   PMID:10873616   PMID:11181995   PMID:11209758   PMID:12477932   PMID:14529681   PMID:14687922   PMID:14702039   PMID:14759258  
PMID:15489334   PMID:16097034   PMID:16169070   PMID:18029348   PMID:18163885   PMID:19615732   PMID:20236318   PMID:20458337   PMID:21044950   PMID:21516116   PMID:21832049   PMID:21873635  
PMID:21926972   PMID:22493238   PMID:22863883   PMID:22939629   PMID:22990118   PMID:23362197   PMID:23376485   PMID:23382044   PMID:23667907   PMID:24322982   PMID:24472318   PMID:25192149  
PMID:25416956   PMID:25581752   PMID:25921289   PMID:26334575   PMID:26344197   PMID:26887037   PMID:27025154   PMID:27153830   PMID:27315786   PMID:28416489   PMID:28514442   PMID:28986522  
PMID:30198396   PMID:30575818   PMID:30711629   PMID:32296183   PMID:32321571   PMID:33549902   PMID:33742751   PMID:33930500   PMID:33961781   PMID:34023852   PMID:34189442   PMID:34314529  
PMID:34591642   PMID:35012549   PMID:35063084   PMID:35256949   PMID:35278345   PMID:35509820   PMID:35745051   PMID:35831314   PMID:35944360   PMID:36215168   PMID:36382663   PMID:36514254  
PMID:37531267   PMID:37628928   PMID:37733154   PMID:37827155   PMID:38655619  


Genomics

Comparative Map Data
DPP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381166,480,434 - 66,509,657 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1166,480,013 - 66,509,657 (+)EnsemblGRCh38hg38GRCh38
GRCh371166,247,905 - 66,277,128 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,004,456 - 66,033,706 (+)NCBINCBI36Build 36hg18NCBI36
Build 341166,004,470 - 66,033,700NCBI
Celera1163,568,130 - 63,597,365 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1162,575,380 - 62,605,040 (+)NCBIHuRef
CHM1_11166,131,228 - 66,160,856 (+)NCBICHM1_1
T2T-CHM13v2.01166,476,691 - 66,505,896 (+)NCBIT2T-CHM13v2.0
Dpp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,957,257 - 4,978,315 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,957,257 - 4,978,315 (-)EnsemblGRCm39 Ensembl
GRCm38194,907,229 - 4,928,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,907,229 - 4,928,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv37194,907,229 - 4,928,287 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36194,907,229 - 4,928,229 (-)NCBIMGSCv36mm8
Celera194,780,315 - 4,801,142 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.15NCBI
Dpp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,634,067 - 211,657,898 (-)NCBIGRCr8
mRatBN7.21202,204,683 - 202,228,501 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,204,693 - 202,228,541 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1210,557,769 - 210,581,666 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,650,095 - 217,673,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,341,122 - 210,364,944 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,166,124 - 220,189,762 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,166,127 - 220,188,541 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,097,122 - 227,120,699 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43138,286,277 - 138,288,887 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13138,191,849 - 138,194,460 (+)NCBI
Celera1199,744,187 - 199,768,442 (-)NCBICelera
Cytogenetic Map1q43NCBI
Dpp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542218,844,138 - 18,865,050 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542218,844,391 - 18,865,050 (-)NCBIChiLan1.0ChiLan1.0
DPP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,706,225 - 67,735,729 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11168,748,922 - 68,778,429 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,836,463 - 61,867,303 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11165,161,889 - 65,191,398 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1165,161,892 - 65,191,398 (+)Ensemblpanpan1.1panPan2
DPP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11850,835,739 - 50,868,777 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1850,835,735 - 50,868,682 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1849,444,448 - 49,477,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01851,874,232 - 51,907,340 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1851,874,233 - 51,907,237 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11850,975,094 - 51,008,130 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01850,548,646 - 50,581,735 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,338,804 - 51,371,895 (-)NCBIUU_Cfam_GSD_1.0
Dpp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049476,634,562 - 6,656,783 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,076,909 - 3,097,785 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,076,909 - 3,098,012 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl25,907,252 - 5,946,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.125,907,251 - 5,948,019 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.224,983,433 - 5,022,962 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.117,766,110 - 7,797,152 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl17,766,160 - 7,795,302 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038105,050,080 - 105,079,951 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dpp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476719,894,279 - 19,916,987 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476719,894,386 - 19,916,996 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DPP3
42 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q13.2(chr11:66193502-67890770)x3 copy number gain See cases [RCV000053623] Chr11:66193502..67890770 [GRCh38]
Chr11:65960973..67658241 [GRCh37]
Chr11:65717549..67414817 [NCBI36]
Chr11:11q13.2		 pathogenic
NM_130443.3(DPP3):c.2100C>T (p.Phe700=) single nucleotide variant Malignant melanoma [RCV000062328] Chr11:66509137 [GRCh38]
Chr11:66276608 [GRCh37]
Chr11:66033184 [NCBI36]
Chr11:11q13.2		 not provided
GRCh38/hg38 11q13.1-13.2(chr11:65741431-67705669)x1 copy number loss See cases [RCV000142881] Chr11:65741431..67705669 [GRCh38]
Chr11:65508902..67473140 [GRCh37]
Chr11:65265478..67229716 [NCBI36]
Chr11:11q13.1-13.2		 pathogenic
GRCh37/hg19 11q13.2(chr11:66024774-67430781)x3 copy number gain See cases [RCV000240374] Chr11:66024774..67430781 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh38/hg38 11q13.2(chr11:66507369-66525103) copy number loss Bardet-Biedl syndrome [RCV000497472] Chr11:66507369..66525103 [GRCh38]
Chr11:66274840..66292574 [GRCh37]
Chr11:11q13.2		 likely pathogenic
NM_130443.4(DPP3):c.573+1G>A single nucleotide variant not provided [RCV000498254] Chr11:66487343 [GRCh38]
Chr11:66254814 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:64501919-67129258)x3 copy number gain See cases [RCV000511632] Chr11:64501919..67129258 [GRCh37]
Chr11:11q13.1-13.2		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_130443.4(DPP3):c.758C>T (p.Pro253Leu) single nucleotide variant not specified [RCV004283924] Chr11:66491343 [GRCh38]
Chr11:66258814 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
NM_130443.4(DPP3):c.1924G>A (p.Glu642Lys) single nucleotide variant not provided [RCV000896537] Chr11:66504657 [GRCh38]
Chr11:66272128 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.271-5C>G single nucleotide variant not provided [RCV000895404] Chr11:66485168 [GRCh38]
Chr11:66252639 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.1203G>A (p.Thr401=) single nucleotide variant not provided [RCV000900580] Chr11:66493086 [GRCh38]
Chr11:66260557 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.271-5C>A single nucleotide variant not provided [RCV000900568] Chr11:66485168 [GRCh38]
Chr11:66252639 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.1269G>A (p.Lys423=) single nucleotide variant not provided [RCV000949779] Chr11:66493152 [GRCh38]
Chr11:66260623 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.993C>T (p.Phe331=) single nucleotide variant not provided [RCV000968220] Chr11:66492720 [GRCh38]
Chr11:66260191 [GRCh37]
Chr11:11q13.2		 benign
GRCh37/hg19 11q13.1-13.2(chr11:65138976-67574402) copy number gain not provided [RCV000767601] Chr11:65138976..67574402 [GRCh37]
Chr11:11q13.1-13.2		 pathogenic
NM_130443.4(DPP3):c.1561C>T (p.His521Tyr) single nucleotide variant not provided [RCV000901396] Chr11:66495473 [GRCh38]
Chr11:66262944 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.227G>A (p.Arg76His) single nucleotide variant not provided [RCV000968219] Chr11:66482427 [GRCh38]
Chr11:66249898 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.1044G>A (p.Ala348=) single nucleotide variant not provided [RCV000921223] Chr11:66492771 [GRCh38]
Chr11:66260242 [GRCh37]
Chr11:11q13.2		 likely benign
NM_130443.4(DPP3):c.487C>A (p.Leu163Met) single nucleotide variant not provided [RCV000881503] Chr11:66486666 [GRCh38]
Chr11:66254137 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.1329C>T (p.Phe443=) single nucleotide variant not provided [RCV000965844] Chr11:66493573 [GRCh38]
Chr11:66261044 [GRCh37]
Chr11:11q13.2		 benign
NM_130443.4(DPP3):c.1994G>C (p.Arg665Pro) single nucleotide variant not specified [RCV004318558] Chr11:66504727 [GRCh38]
Chr11:66272198 [GRCh37]
Chr11:11q13.2		 uncertain significance
NC_000011.9:g.(?_64973914)_(70052579_?)dup duplication Aicardi-Goutieres syndrome 3 [RCV003113322]|FADD-related immunodeficiency [RCV003107753] Chr11:64973914..70052579 [GRCh37]
Chr11:11q13.1-13.3		 uncertain significance
NM_130443.4(DPP3):c.498+9C>G single nucleotide variant not provided [RCV000974264] Chr11:66486686 [GRCh38]
Chr11:66254157 [GRCh37]
Chr11:11q13.2		 benign
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Familial temporal lobe epilepsy 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3		 uncertain significance
GRCh37/hg19 11q13.2(chr11:65963737-66581485)x1 copy number loss not provided [RCV001827874] Chr11:65963737..66581485 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q13.2(chr11:66188172-66402747) copy number gain not specified [RCV002052931] Chr11:66188172..66402747 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q13.1-13.2(chr11:64935724-66405514) copy number loss not specified [RCV002052930] Chr11:64935724..66405514 [GRCh37]
Chr11:11q13.1-13.2		 uncertain significance
NC_000011.9:g.(?_64522783)_(66283694_?)del deletion Bardet-Biedl syndrome [RCV002014493]|Glycogen storage disease, type V [RCV002004587] Chr11:64522783..66283694 [GRCh37]
Chr11:11q13.1-13.2		 pathogenic
NC_000011.9:g.(?_66099747)_(66291373_?)dup duplication Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A13 [RCV003109574] Chr11:66099747..66291373 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1612G>A (p.Val538Met) single nucleotide variant not specified [RCV004308634] Chr11:66495664 [GRCh38]
Chr11:66263135 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
NM_130443.4(DPP3):c.757C>T (p.Pro253Ser) single nucleotide variant not specified [RCV004330392] Chr11:66491342 [GRCh38]
Chr11:66258813 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q13.2(chr11:66178392-66433436)x3 copy number gain not provided [RCV002511719] Chr11:66178392..66433436 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.442G>A (p.Gly148Arg) single nucleotide variant not specified [RCV004127146] Chr11:66486621 [GRCh38]
Chr11:66254092 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.29A>G (p.Asn10Ser) single nucleotide variant not specified [RCV004226606] Chr11:66482229 [GRCh38]
Chr11:66249700 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.65C>G (p.Ala22Gly) single nucleotide variant not specified [RCV004133274] Chr11:66482265 [GRCh38]
Chr11:66249736 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.478C>T (p.His160Tyr) single nucleotide variant not specified [RCV004093789] Chr11:66486657 [GRCh38]
Chr11:66254128 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.754G>A (p.Ala252Thr) single nucleotide variant not specified [RCV004192727] Chr11:66491339 [GRCh38]
Chr11:66258810 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.909C>A (p.Asp303Glu) single nucleotide variant not specified [RCV004180216] Chr11:66491604 [GRCh38]
Chr11:66259075 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1034G>A (p.Arg345Gln) single nucleotide variant not specified [RCV004122945] Chr11:66492761 [GRCh38]
Chr11:66260232 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.116G>A (p.Arg39His) single nucleotide variant not specified [RCV004116917] Chr11:66482316 [GRCh38]
Chr11:66249787 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.742C>T (p.Arg248Trp) single nucleotide variant not specified [RCV004121166] Chr11:66491327 [GRCh38]
Chr11:66258798 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1261C>T (p.Arg421Trp) single nucleotide variant not specified [RCV004076589] Chr11:66493144 [GRCh38]
Chr11:66260615 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.272C>T (p.Ala91Val) single nucleotide variant not specified [RCV004169798] Chr11:66485174 [GRCh38]
Chr11:66252645 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1589T>C (p.Phe530Ser) single nucleotide variant not specified [RCV004176251] Chr11:66495641 [GRCh38]
Chr11:66263112 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1384G>A (p.Val462Ile) single nucleotide variant not specified [RCV004262026] Chr11:66493628 [GRCh38]
Chr11:66261099 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q13.2(chr11:66274870-66292647)x1 copy number loss Bardet-Biedl syndrome 1 [RCV003229560] Chr11:66274870..66292647 [GRCh37]
Chr11:11q13.2		 pathogenic
NM_130443.4(DPP3):c.1852C>G (p.Leu618Val) single nucleotide variant not specified [RCV004273366] Chr11:66497451 [GRCh38]
Chr11:66264922 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1424C>T (p.Thr475Ile) single nucleotide variant not specified [RCV004266710] Chr11:66495240 [GRCh38]
Chr11:66262711 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.839A>G (p.Gln280Arg) single nucleotide variant not specified [RCV004265784] Chr11:66491534 [GRCh38]
Chr11:66259005 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.217G>A (p.Asp73Asn) single nucleotide variant not specified [RCV004316171] Chr11:66482417 [GRCh38]
Chr11:66249888 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1993C>T (p.Arg665Cys) single nucleotide variant not specified [RCV004347277] Chr11:66504726 [GRCh38]
Chr11:66272197 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1228G>A (p.Gly410Arg) single nucleotide variant not specified [RCV004360211] Chr11:66493111 [GRCh38]
Chr11:66260582 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1643G>A (p.Arg548Gln) single nucleotide variant not specified [RCV004340353] Chr11:66495695 [GRCh38]
Chr11:66263166 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.70C>T (p.Arg24Cys) single nucleotide variant not specified [RCV004347667] Chr11:66482270 [GRCh38]
Chr11:66249741 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.871G>A (p.Glu291Lys) single nucleotide variant not specified [RCV004345008] Chr11:66491566 [GRCh38]
Chr11:66259037 [GRCh37]
Chr11:11q13.2		 uncertain significance
GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 copy number gain not provided [RCV003484842] Chr11:59923608..76272324 [GRCh37]
Chr11:11q12.2-13.5		 pathogenic
GRCh37/hg19 11q12.1-13.3(chr11:56895955-69295402)x3 copy number gain not specified [RCV003986944] Chr11:56895955..69295402 [GRCh37]
Chr11:11q12.1-13.3		 likely pathogenic
NM_130443.4(DPP3):c.19A>C (p.Ile7Leu) single nucleotide variant not specified [RCV004384376] Chr11:66482219 [GRCh38]
Chr11:66249690 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.59G>A (p.Arg20His) single nucleotide variant not specified [RCV004384383] Chr11:66482259 [GRCh38]
Chr11:66249730 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.718C>T (p.Arg240Trp) single nucleotide variant not specified [RCV004384387] Chr11:66491303 [GRCh38]
Chr11:66258774 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.994G>A (p.Val332Ile) single nucleotide variant not specified [RCV004384388] Chr11:66492721 [GRCh38]
Chr11:66260192 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.323C>A (p.Ser108Tyr) single nucleotide variant not specified [RCV004384380] Chr11:66485225 [GRCh38]
Chr11:66252696 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1954C>T (p.Pro652Ser) single nucleotide variant not specified [RCV004384375] Chr11:66504687 [GRCh38]
Chr11:66272158 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.47G>A (p.Ser16Asn) single nucleotide variant not specified [RCV004384382] Chr11:66482247 [GRCh38]
Chr11:66249718 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.676C>G (p.Leu226Val) single nucleotide variant not specified [RCV004384385] Chr11:66491261 [GRCh38]
Chr11:66258732 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1711G>T (p.Ala571Ser) single nucleotide variant not specified [RCV004384371] Chr11:66497310 [GRCh38]
Chr11:66264781 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1789G>A (p.Gly597Arg) single nucleotide variant not specified [RCV004384372] Chr11:66497388 [GRCh38]
Chr11:66264859 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1949C>T (p.Ala650Val) single nucleotide variant not specified [RCV004384374] Chr11:66504682 [GRCh38]
Chr11:66272153 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.2128G>A (p.Glu710Lys) single nucleotide variant not specified [RCV004384377] Chr11:66509165 [GRCh38]
Chr11:66276636 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1144G>C (p.Ala382Pro) single nucleotide variant not specified [RCV004384369] Chr11:66492871 [GRCh38]
Chr11:66260342 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1795C>T (p.Pro599Ser) single nucleotide variant not specified [RCV004384373] Chr11:66497394 [GRCh38]
Chr11:66264865 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.613G>A (p.Asp205Asn) single nucleotide variant not specified [RCV004384384] Chr11:66487953 [GRCh38]
Chr11:66255424 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.167C>T (p.Ala56Val) single nucleotide variant not specified [RCV004384370] Chr11:66482367 [GRCh38]
Chr11:66249838 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.256G>A (p.Glu86Lys) single nucleotide variant not specified [RCV004384378] Chr11:66482456 [GRCh38]
Chr11:66249927 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.34A>G (p.Ile12Val) single nucleotide variant not specified [RCV004384381] Chr11:66482234 [GRCh38]
Chr11:66249705 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1555T>A (p.Cys519Ser) single nucleotide variant not specified [RCV004619719] Chr11:66495467 [GRCh38]
Chr11:66262938 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1744G>T (p.Ala582Ser) single nucleotide variant not specified [RCV004619705] Chr11:66497343 [GRCh38]
Chr11:66264814 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.226C>T (p.Arg76Cys) single nucleotide variant not specified [RCV004619708] Chr11:66482426 [GRCh38]
Chr11:66249897 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.949A>G (p.Ser317Gly) single nucleotide variant not specified [RCV004619715] Chr11:66491717 [GRCh38]
Chr11:66259188 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.175A>C (p.Ile59Leu) single nucleotide variant not specified [RCV004619717] Chr11:66482375 [GRCh38]
Chr11:66249846 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.628C>T (p.Pro210Ser) single nucleotide variant not specified [RCV004619706] Chr11:66487968 [GRCh38]
Chr11:66255439 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.846A>G (p.Ile282Met) single nucleotide variant not specified [RCV004619709] Chr11:66491541 [GRCh38]
Chr11:66259012 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1498A>T (p.Ser500Cys) single nucleotide variant not specified [RCV004619711] Chr11:66495410 [GRCh38]
Chr11:66262881 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.169C>T (p.Pro57Ser) single nucleotide variant not specified [RCV004619716] Chr11:66482369 [GRCh38]
Chr11:66249840 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1742A>C (p.Glu581Ala) single nucleotide variant not specified [RCV004619720] Chr11:66497341 [GRCh38]
Chr11:66264812 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.2189G>T (p.Ser730Ile) single nucleotide variant not specified [RCV004619714] Chr11:66509226 [GRCh38]
Chr11:66276697 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.638A>T (p.Glu213Val) single nucleotide variant not specified [RCV004619712] Chr11:66487978 [GRCh38]
Chr11:66255449 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.893G>A (p.Arg298His) single nucleotide variant not specified [RCV004619710] Chr11:66491588 [GRCh38]
Chr11:66259059 [GRCh37]
Chr11:11q13.2		 uncertain significance
NM_130443.4(DPP3):c.1072C>T (p.Pro358Ser) single nucleotide variant not specified [RCV004619713] Chr11:66492799 [GRCh38]
Chr11:66260270 [GRCh37]
Chr11:11q13.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5773
Count of miRNA genes:1016
Interacting mature miRNAs:1296
Transcripts:ENST00000360510, ENST00000453114, ENST00000525738, ENST00000526250, ENST00000526515, ENST00000526667, ENST00000530165, ENST00000531272, ENST00000531314, ENST00000531354, ENST00000531863, ENST00000532019, ENST00000532677, ENST00000533725, ENST00000533799, ENST00000539085, ENST00000541961, ENST00000544603
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357380BW64_HBody weight QTL 64 (human)2.2Body weightpercent fat after exercise training116097893786978937Human
407281678GWAS930654_Hbody height QTL GWAS930654 (human)7e-76body height (VT:0001253)body height (CMO:0000106)116648820366488204Human
407329406GWAS978382_Hnon-high density lipoprotein cholesterol measurement QTL GWAS978382 (human)1e-09non-high density lipoprotein cholesterol measurementblood non-high density lipoprotein cholesterol level (CMO:0003967)116648804466488045Human
407189403GWAS838379_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS838379 (human)4e-09triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)116648661466486615Human
407346857GWAS995833_Htotal cholesterol measurement QTL GWAS995833 (human)1e-15total cholesterol measurementblood total cholesterol level (CMO:0000051)116650550566505506Human

Markers in Region
RH47804  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371166,248,271 - 66,248,400UniSTSGRCh37
Build 361166,004,847 - 66,004,976RGDNCBI36
Celera1163,568,521 - 63,568,650RGD
Cytogenetic Map11q12-q13.1UniSTS
HuRef1162,576,167 - 62,576,296UniSTS
GeneMap99-GB4 RH Map11249.75UniSTS
NCBI RH Map11578.5UniSTS
RH47870  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371166,247,871 - 66,248,006UniSTSGRCh37
Build 361166,004,447 - 66,004,582RGDNCBI36
Celera1163,568,121 - 63,568,256RGD
Cytogenetic Map11q12-q13.1UniSTS
HuRef1162,575,767 - 62,575,902UniSTS
GeneMap99-GB4 RH Map11251.45UniSTS
SHGC-59694  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37976,090,184 - 76,090,406UniSTSGRCh37
GRCh37465,297,600 - 65,297,822UniSTSGRCh37
Build 36464,980,195 - 64,980,417RGDNCBI36
Celera946,662,787 - 46,663,009UniSTS
Celera462,758,056 - 62,758,278RGD
Cytogenetic Map11q12-q13.1UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map4q13.1UniSTS
HuRef945,911,724 - 45,911,946UniSTS
HuRef461,207,844 - 61,208,066UniSTS
GeneMap99-GB4 RH Map4378.76UniSTS
G60290  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q12-q13.1UniSTS
D4S3182  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q12-q13.1UniSTS
Whitehead-YAC Contig Map4 UniSTS
SHGC-8631  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q12-q13.1UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_032068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001256670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_130443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ271216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK021449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP002748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD366941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC325853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC403406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC407885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ793449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000525738
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,492,467 - 66,493,179 (+)Ensembl
Ensembl Acc Id: ENST00000526250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,491,605 - 66,495,750 (+)Ensembl
Ensembl Acc Id: ENST00000526515   ⟹   ENSP00000431606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,438 - 66,487,941 (+)Ensembl
Ensembl Acc Id: ENST00000526667
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,491,731 - 66,495,750 (+)Ensembl
Ensembl Acc Id: ENST00000530165   ⟹   ENSP00000436941
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,438 - 66,509,345 (+)Ensembl
Ensembl Acc Id: ENST00000531272
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,434 - 66,486,592 (+)Ensembl
Ensembl Acc Id: ENST00000531314   ⟹   ENSP00000436820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,741 - 66,482,470 (+)Ensembl
Ensembl Acc Id: ENST00000531354   ⟹   ENSP00000432618
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,482,071 - 66,487,943 (+)Ensembl
Ensembl Acc Id: ENST00000531863   ⟹   ENSP00000432782
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,434 - 66,509,657 (+)Ensembl
Ensembl Acc Id: ENST00000532019   ⟹   ENSP00000437101
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,435 - 66,487,958 (+)Ensembl
Ensembl Acc Id: ENST00000532677   ⟹   ENSP00000435284
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,013 - 66,509,657 (+)Ensembl
Ensembl Acc Id: ENST00000533725   ⟹   ENSP00000434518
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,439 - 66,491,533 (+)Ensembl
Ensembl Acc Id: ENST00000533799
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,492,429 - 66,495,424 (+)Ensembl
Ensembl Acc Id: ENST00000539085
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,504,645 - 66,509,331 (+)Ensembl
Ensembl Acc Id: ENST00000541961   ⟹   ENSP00000440502
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,431 - 66,509,657 (+)Ensembl
Ensembl Acc Id: ENST00000544603
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1166,480,444 - 66,486,599 (+)Ensembl
RefSeq Acc Id: NM_001256670   ⟹   NP_001243599
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,480,434 - 66,509,657 (+)NCBI
GRCh371166,247,484 - 66,277,130 (+)NCBI
HuRef1162,575,380 - 62,605,040 (+)NCBI
CHM1_11166,131,228 - 66,160,856 (+)NCBI
T2T-CHM13v2.01166,476,691 - 66,505,896 (+)NCBI
Sequence:
RefSeq Acc Id: NM_005700   ⟹   NP_005691
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,480,434 - 66,509,657 (+)NCBI
GRCh371166,247,484 - 66,277,130 (+)NCBI
Build 361166,004,456 - 66,033,706 (+)NCBI Archive
HuRef1162,575,380 - 62,605,040 (+)NCBI
CHM1_11166,131,228 - 66,160,856 (+)NCBI
T2T-CHM13v2.01166,476,691 - 66,505,896 (+)NCBI
Sequence:
RefSeq Acc Id: NM_130443   ⟹   NP_569710
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,480,434 - 66,509,657 (+)NCBI
GRCh371166,247,484 - 66,277,130 (+)NCBI
Build 361166,004,456 - 66,033,706 (+)NCBI Archive
HuRef1162,575,380 - 62,605,040 (+)NCBI
CHM1_11166,131,228 - 66,160,856 (+)NCBI
T2T-CHM13v2.01166,476,691 - 66,505,896 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001243599 (Get FASTA)   NCBI Sequence Viewer  
  NP_005691 (Get FASTA)   NCBI Sequence Viewer  
  NP_569710 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH01446 (Get FASTA)   NCBI Sequence Viewer  
  AAH07221 (Get FASTA)   NCBI Sequence Viewer  
  AAH14038 (Get FASTA)   NCBI Sequence Viewer  
  AAH24271 (Get FASTA)   NCBI Sequence Viewer  
  BAA75785 (Get FASTA)   NCBI Sequence Viewer  
  BAB13828 (Get FASTA)   NCBI Sequence Viewer  
  BAD96286 (Get FASTA)   NCBI Sequence Viewer  
  BAD96567 (Get FASTA)   NCBI Sequence Viewer  
  BAG37862 (Get FASTA)   NCBI Sequence Viewer  
  BAG59686 (Get FASTA)   NCBI Sequence Viewer  
  BAG65369 (Get FASTA)   NCBI Sequence Viewer  
  CAB72433 (Get FASTA)   NCBI Sequence Viewer  
  CAI46122 (Get FASTA)   NCBI Sequence Viewer  
  EAW74538 (Get FASTA)   NCBI Sequence Viewer  
  EAW74539 (Get FASTA)   NCBI Sequence Viewer  
  EAW74540 (Get FASTA)   NCBI Sequence Viewer  
  EAW74541 (Get FASTA)   NCBI Sequence Viewer  
  EAW74543 (Get FASTA)   NCBI Sequence Viewer  
  EAW74544 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000431606.1
  ENSP00000432618.2
  ENSP00000432782
  ENSP00000432782.2
  ENSP00000434518.1
  ENSP00000435284
  ENSP00000435284.1
  ENSP00000436820.1
  ENSP00000436941
  ENSP00000436941.1
  ENSP00000437101.1
  ENSP00000440502.1
GenBank Protein Q9NY33 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_569710   ⟸   NM_130443
- Peptide Label: isoform 1
- UniProtKB: Q9BV67 (UniProtKB/Swiss-Prot),   Q969H2 (UniProtKB/Swiss-Prot),   O95748 (UniProtKB/Swiss-Prot),   F5H8L6 (UniProtKB/Swiss-Prot),   B4DLX4 (UniProtKB/Swiss-Prot),   B2RDB5 (UniProtKB/Swiss-Prot),   Q9HAL6 (UniProtKB/Swiss-Prot),   Q9NY33 (UniProtKB/Swiss-Prot),   Q5JPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_005691   ⟸   NM_005700
- Peptide Label: isoform 1
- UniProtKB: Q9BV67 (UniProtKB/Swiss-Prot),   Q969H2 (UniProtKB/Swiss-Prot),   O95748 (UniProtKB/Swiss-Prot),   F5H8L6 (UniProtKB/Swiss-Prot),   B4DLX4 (UniProtKB/Swiss-Prot),   B2RDB5 (UniProtKB/Swiss-Prot),   Q9HAL6 (UniProtKB/Swiss-Prot),   Q9NY33 (UniProtKB/Swiss-Prot),   Q5JPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001243599   ⟸   NM_001256670
- Peptide Label: isoform 2
- UniProtKB: Q5JPB8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000440502   ⟸   ENST00000541961
Ensembl Acc Id: ENSP00000436941   ⟸   ENST00000530165
Ensembl Acc Id: ENSP00000432782   ⟸   ENST00000531863
Ensembl Acc Id: ENSP00000436820   ⟸   ENST00000531314
Ensembl Acc Id: ENSP00000432618   ⟸   ENST00000531354
Ensembl Acc Id: ENSP00000437101   ⟸   ENST00000532019
Ensembl Acc Id: ENSP00000435284   ⟸   ENST00000532677
Ensembl Acc Id: ENSP00000434518   ⟸   ENST00000533725
Ensembl Acc Id: ENSP00000431606   ⟸   ENST00000526515

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9NY33-F1-model_v2 AlphaFold Q9NY33 1-737 view protein structure

Promoters
RGD ID:6788738
Promoter ID:HG_KWN:13408
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000347422,   NM_005700,   NM_130443
Position:
Human AssemblyChrPosition (strand)Source
Build 361166,003,846 - 66,004,547 (+)MPROMDB
RGD ID:7221153
Promoter ID:EPDNEW_H16323
Type:initiation region
Name:DPP3_1
Description:dipeptidyl peptidase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16325  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,480,016 - 66,480,076EPDNEW
RGD ID:7221159
Promoter ID:EPDNEW_H16325
Type:initiation region
Name:DPP3_2
Description:dipeptidyl peptidase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16323  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381166,509,383 - 66,509,443EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:3008 AgrOrtholog
COSMIC DPP3 COSMIC
Ensembl Genes ENSG00000254986 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000526515.5 UniProtKB/TrEMBL
  ENST00000530165 ENTREZGENE
  ENST00000530165.5 UniProtKB/Swiss-Prot
  ENST00000531314.1 UniProtKB/TrEMBL
  ENST00000531354.2 UniProtKB/TrEMBL
  ENST00000531863 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000531863.6 UniProtKB/Swiss-Prot
  ENST00000532019.5 UniProtKB/TrEMBL
  ENST00000532677 ENTREZGENE
  ENST00000532677.5 UniProtKB/TrEMBL
  ENST00000533725.5 UniProtKB/TrEMBL
  ENST00000541961.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.540.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.2600 UniProtKB/TrEMBL
GTEx ENSG00000254986 GTEx
HGNC ID HGNC:3008 ENTREZGENE
Human Proteome Map DPP3 Human Proteome Map
InterPro Dipeptidyl-peptase3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M49 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10072 UniProtKB/Swiss-Prot
NCBI Gene 10072 ENTREZGENE
OMIM 606818 OMIM
PANTHER DIPEPTIDYL PEPTIDASE 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23422 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_M49 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA27466 PharmGKB
PIRSF Dipeptidyl-peptidase_III UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RDB5 ENTREZGENE
  B4DLX4 ENTREZGENE
  DPP3_HUMAN UniProtKB/Swiss-Prot
  E9PKK8_HUMAN UniProtKB/TrEMBL
  E9PNX5_HUMAN UniProtKB/TrEMBL
  E9PPK9_HUMAN UniProtKB/TrEMBL
  E9PQ14_HUMAN UniProtKB/TrEMBL
  E9PQF2_HUMAN UniProtKB/TrEMBL
  F5H8L6 ENTREZGENE
  G3V180_HUMAN UniProtKB/TrEMBL
  G3V1D3_HUMAN UniProtKB/TrEMBL
  O95748 ENTREZGENE
  Q5JPB8 ENTREZGENE, UniProtKB/TrEMBL
  Q969H2 ENTREZGENE
  Q9BV67 ENTREZGENE
  Q9HAL6 ENTREZGENE
  Q9NY33 ENTREZGENE
UniProt Secondary A0A024R5G5 UniProtKB/TrEMBL
  B2RDB5 UniProtKB/Swiss-Prot
  B4DLX4 UniProtKB/Swiss-Prot
  F5H8L6 UniProtKB/Swiss-Prot
  O95748 UniProtKB/Swiss-Prot
  Q969H2 UniProtKB/Swiss-Prot
  Q9BV67 UniProtKB/Swiss-Prot
  Q9HAL6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-08 DPP3  dipeptidyl peptidase 3    dipeptidyl-peptidase 3  Symbol and/or name change 5135510 APPROVED