Hip1 (huntingtin interacting protein 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hip1 (huntingtin interacting protein 1) Mus musculus
Analyze
Symbol: Hip1
Name: huntingtin interacting protein 1
RGD ID: 736004
MGI Page MGI
Description: Predicted to enable several functions, including AP-2 adaptor complex binding activity; phosphatidylinositol phosphate binding activity; and protein dimerization activity. Involved in endocytosis; presynaptic modulation of chemical synaptic transmission; and regulation of receptor-mediated endocytosis. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including brain; heart; and testis. Orthologous to human HIP1 (huntingtin interacting protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2610109B09Rik; A930014B11Rik; E130315I21Rik; HIP; HIP-I; huntingtin-interacting protein 1; huntingtin-interacting protein I; KIAA4113; MGC27616; mKIAA4113
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,435,350 - 135,574,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,435,385 - 135,573,974 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385135,406,496 - 135,545,323 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,406,531 - 135,545,120 (-)Ensemblmm10GRCm38
MGSCv375135,882,388 - 136,020,992 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365135,692,653 - 135,829,742 (-)NCBIMGSCv36mm8
Celera5132,418,220 - 132,556,655 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.18NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
clotrimazole  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
ethanol  (EXP,ISO)
folic acid  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
glycine betaine  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methoxychlor  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitrofen  (ISO)
p-toluidine  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
phosgene  (EXP)
pinostrobin  (ISO)
potassium chromate  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
succimer  (EXP)
tamoxifen  (ISO)
testosterone  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal amino acid level  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal cornea morphology  (IEA)
abnormal definitive hematopoiesis  (IAGP)
abnormal enzyme/coenzyme level  (IAGP)
abnormal gait  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver parenchyma morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal metabolism  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal muscle morphology  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal spine curvature  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal tumor incidence  (IAGP)
abnormal tumor morphology  (IAGP)
abnormal vertebrae morphology  (IEA)
abnormal vertebral body morphology  (IAGP)
abnormal vertebral column morphology  (IAGP)
abnormal vitamin homeostasis  (IAGP)
absent common myeloid progenitor cells  (IAGP)
cataract  (IAGP)
cornea opacity  (IEA)
decreased acetylcholine level  (IAGP)
decreased body length  (IEA)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased circulating creatinine level  (IEA)
decreased common myeloid progenitor cell number  (IAGP)
decreased cystathionine level  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased locomotor activity  (IAGP)
decreased male germ cell number  (IAGP)
decreased phosphocholine level  (IAGP)
decreased startle reflex  (IEA)
decreased testis weight  (IAGP)
decreased vertical activity  (IEA)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
hunched posture  (IAGP)
hyperactivity  (IEA)
increased bone mineral content  (IEA)
increased chronic myelocytic leukemia incidence  (IAGP)
increased granulocyte number  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased hepatocellular carcinoma incidence  (IAGP)
increased leukocyte cell number  (IAGP)
increased liver tumor incidence  (IAGP)
increased liver weight  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased neutrophil cell number  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
kyphosis  (IAGP)
lordokyphosis  (IAGP)
male infertility  (IAGP)
microphthalmia  (IAGP)
multinucleated giant male germ cells  (IAGP)
no abnormal phenotype detected  (IAGP)
nuclear cataract  (IAGP)
oligozoospermia  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
reduced male fertility  (IAGP)
seminiferous tubule degeneration  (IAGP)
short stride length  (IAGP)
small lens  (IAGP)
spleen hyperplasia  (IAGP)
testicular atrophy  (IAGP)
testis degeneration  (IAGP)
tremors  (IAGP)
weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Easterday MC, etal., Dev Biol 2003 Dec 15;264(2):309-22.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. Mishra SK, etal., J Biol Chem 2001 Dec 7;276(49):46230-6. Epub 2001 Sep 27.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. Comparative analysis of apoptosis and inflammation genes of mice and humans. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s). Valero MC, etal., Genomics 2000 Oct 1;69(1):1-13.
Additional References at PubMed
PMID:8889548   PMID:9434941   PMID:9502734   PMID:9878248   PMID:10198163   PMID:10349636   PMID:10512203   PMID:10575226   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11604514  
PMID:11779826   PMID:11788820   PMID:12403705   PMID:12520002   PMID:12569124   PMID:12781365   PMID:12839988   PMID:14610273   PMID:14681479   PMID:14998932   PMID:15075292   PMID:15121852  
PMID:15840001   PMID:15899803   PMID:16141072   PMID:16141073   PMID:16967501   PMID:17329427   PMID:17452370   PMID:17928447   PMID:17967808   PMID:18281481   PMID:18790740   PMID:18799693  
PMID:19647224   PMID:21677750   PMID:21697888   PMID:21873635   PMID:23836884   PMID:24240679   PMID:24457600   PMID:24659689   PMID:25122462   PMID:28011632   PMID:28190767   PMID:30224518  
PMID:32581705   PMID:34321999   PMID:34821552   PMID:35364055   PMID:35449600   PMID:35472633   PMID:38355793  


Genomics

Comparative Map Data
Hip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,435,350 - 135,574,167 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,435,385 - 135,573,974 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385135,406,496 - 135,545,323 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,406,531 - 135,545,120 (-)Ensemblmm10GRCm38
MGSCv375135,882,388 - 136,020,992 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365135,692,653 - 135,829,742 (-)NCBIMGSCv36mm8
Celera5132,418,220 - 132,556,655 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.18NCBI
HIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,533,298 - 75,738,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl775,533,298 - 75,738,986 (-)Ensemblhg38GRCh38
GRCh37775,162,619 - 75,368,259 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,001,345 - 75,206,215 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34774,808,059 - 75,012,930NCBI
Celera770,031,212 - 70,236,048 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef770,248,359 - 70,453,525 (-)NCBIHuRef
CHM1_1775,092,714 - 75,298,283 (-)NCBICHM1_1
T2T-CHM13v2.0776,820,630 - 77,026,024 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,495,683 - 74,701,354 (-)NCBI
Hip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,769,868 - 26,904,367 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,769,961 - 26,904,296 (+)EnsemblGRCr8
mRatBN7.21221,133,364 - 21,267,796 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,133,406 - 21,267,725 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1222,275,219 - 22,409,598 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,887,561 - 23,021,930 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,954,027 - 22,088,410 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,180,795 - 24,315,373 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,180,937 - 24,315,373 (+)Ensemblrn6Rnor6.0
Rnor_5.01226,178,145 - 26,312,676 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,287,861 - 22,422,163 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,895,802 - 23,030,274 (+)NCBICelera
RGSC_v3.11222,396,520 - 22,408,493 (+)NCBI
Cytogenetic Map12q12NCBI
Hip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,392,921 - 14,529,213 (-)Ensembl
ChiLan1.0NW_00495545614,389,282 - 14,529,317 (-)NCBIChiLan1.0ChiLan1.0
HIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2694,215,412 - 94,420,460 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17142,480,052 - 142,685,098 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0768,281,899 - 68,464,233 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1782,187,193 - 82,193,058 (-)NCBIPanPan1.1PanPan1.1panPan2
HIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,957,760 - 7,115,676 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,961,053 - 7,115,618 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha68,654,406 - 8,812,467 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.066,778,147 - 6,936,340 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,778,151 - 6,936,438 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,747,968 - 6,905,918 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,711,133 - 6,869,280 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,874,374 - 7,032,555 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,467,552 - 131,540,287 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,522,154 - 2,565,376 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,496,301 - 2,569,019 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,416,475 - 10,578,366 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1310,416,418 - 10,578,374 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,176,878 - 10,282,562 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,805,985 - 10,007,931 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl289,807,672 - 9,914,047 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660706,432,081 - 6,658,245 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,464,372 - 14,607,130 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474014,460,742 - 14,607,203 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hip1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11618,476,398 - 18,606,670 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hip1
9108 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2103
Count of miRNA genes:800
Interacting mature miRNAs:1064
Transcripts:ENSMUST00000060311
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse

Markers in Region
UniSTS:235335  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385135,408,785 - 135,409,030UniSTSGRCm38
MGSCv375135,884,655 - 135,884,900UniSTSGRCm37
Celera5132,420,487 - 132,420,732UniSTS
Cytogenetic Map5F-G2UniSTS
UniSTS:235336  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385135,409,407 - 135,409,635UniSTSGRCm38
MGSCv375135,885,277 - 135,885,505UniSTSGRCm37
Celera5132,421,109 - 132,421,337UniSTS
Cytogenetic Map5F-G2UniSTS
Hip1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385135,414,267 - 135,414,481UniSTSGRCm38
MGSCv375135,890,137 - 135,890,351UniSTSGRCm37
Celera5132,425,969 - 132,426,183UniSTS
Cytogenetic Map5F-G2UniSTS
cM Map575.0UniSTS
Hip1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5F-G2UniSTS
cM Map575.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001382848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_146001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_168637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011240878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036164990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004942493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC024608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK020853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY309818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF746398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000060311   ⟹   ENSMUSP00000059033
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,435,385 - 135,573,969 (-)Ensembl
GRCm38.p6 Ensembl5135,406,531 - 135,545,115 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200808   ⟹   ENSMUSP00000144429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,459,075 - 135,469,178 (-)Ensembl
GRCm38.p6 Ensembl5135,430,221 - 135,440,324 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,463,293 - 135,573,974 (-)Ensembl
GRCm38.p6 Ensembl5135,434,439 - 135,545,120 (-)Ensembl
Ensembl Acc Id: ENSMUST00000201479
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,457,769 - 135,458,948 (-)Ensembl
GRCm38.p6 Ensembl5135,428,915 - 135,430,094 (-)Ensembl
Ensembl Acc Id: ENSMUST00000201998   ⟹   ENSMUSP00000144392
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,478,603 - 135,518,112 (-)Ensembl
GRCm38.p6 Ensembl5135,449,749 - 135,489,258 (-)Ensembl
Ensembl Acc Id: ENSMUST00000202044
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,487,935 - 135,573,969 (-)Ensembl
GRCm38.p6 Ensembl5135,459,081 - 135,545,115 (-)Ensembl
Ensembl Acc Id: ENSMUST00000202095
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,481,256 - 135,487,059 (-)Ensembl
GRCm38.p6 Ensembl5135,452,402 - 135,458,205 (-)Ensembl
Ensembl Acc Id: ENSMUST00000202236
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,467,388 - 135,481,372 (-)Ensembl
GRCm38.p6 Ensembl5135,438,534 - 135,452,518 (-)Ensembl
Ensembl Acc Id: ENSMUST00000202643   ⟹   ENSMUSP00000144086
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,435,389 - 135,464,002 (-)Ensembl
GRCm38.p6 Ensembl5135,406,535 - 135,435,148 (-)Ensembl
Ensembl Acc Id: ENSMUST00000212301   ⟹   ENSMUSP00000148842
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5135,464,969 - 135,494,781 (-)Ensembl
GRCm38.p6 Ensembl5135,436,115 - 135,465,927 (-)Ensembl
RefSeq Acc Id: NM_001382848   ⟹   NP_001369777
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,350 - 135,518,083 (-)NCBI
GRCm385135,406,496 - 135,489,229 (-)NCBI
Sequence:
RefSeq Acc Id: NM_146001   ⟹   NP_666113
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,372 - 135,573,976 (-)NCBI
GRCm385135,406,518 - 135,545,122 (-)NCBI
MGSCv375135,882,388 - 136,020,992 (-)RGD
Celera5132,418,220 - 132,556,655 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_168637
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,350 - 135,518,083 (-)NCBI
GRCm385135,406,496 - 135,489,229 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011240878   ⟹   XP_011239180
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,574,164 (-)NCBI
GRCm385135,406,531 - 135,545,120 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164985   ⟹   XP_036020878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,574,164 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164986   ⟹   XP_036020879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,574,164 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164987   ⟹   XP_036020880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,511,637 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164988   ⟹   XP_036020881
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,388 - 135,518,146 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164989   ⟹   XP_036020882
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,518,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036164990   ⟹   XP_036020883
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,518,577 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942493
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395135,435,385 - 135,574,167 (-)NCBI
Sequence:
RefSeq Acc Id: NP_666113   ⟸   NM_146001
- Peptide Label: isoform 1
- UniProtKB: Q8VD75 (UniProtKB/Swiss-Prot),   Q571K7 (UniProtKB/Swiss-Prot),   Q3TLS2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011239180   ⟸   XM_011240878
- Peptide Label: isoform X2
- UniProtKB: Q8VD75 (UniProtKB/Swiss-Prot),   Q571K7 (UniProtKB/Swiss-Prot),   Q3TLS2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001369777   ⟸   NM_001382848
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000144086   ⟸   ENSMUST00000202643
Ensembl Acc Id: ENSMUSP00000059033   ⟸   ENSMUST00000060311
Ensembl Acc Id: ENSMUSP00000148842   ⟸   ENSMUST00000212301
Ensembl Acc Id: ENSMUSP00000144392   ⟸   ENSMUST00000201998
Ensembl Acc Id: ENSMUSP00000144429   ⟸   ENSMUST00000200808
RefSeq Acc Id: XP_036020879   ⟸   XM_036164986
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036020878   ⟸   XM_036164985
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036020882   ⟸   XM_036164989
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036020883   ⟸   XM_036164990
- Peptide Label: isoform X5
RefSeq Acc Id: XP_036020880   ⟸   XM_036164987
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036020881   ⟸   XM_036164988
- Peptide Label: isoform X3
Protein Domains
ENTH   I/LWEQ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VD75-F1-model_v2 AlphaFold Q8VD75 1-1029 view protein structure

Promoters
RGD ID:6888324
Promoter ID:EPDNEW_M7613
Type:initiation region
Name:Hip1_1
Description:Mus musculus huntingtin interacting protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385135,545,071 - 135,545,131EPDNEW
RGD ID:6837700
Promoter ID:MM_KWN:44356
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:UC008ZYJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,910,721 - 135,911,221 (-)MPROMDB
RGD ID:6837701
Promoter ID:MM_KWN:44357
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:UC008ZYL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,933,886 - 135,934,732 (-)MPROMDB
RGD ID:6847919
Promoter ID:MM_ACW:39780
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   ES_Cell,   Lung
Transcripts:HIP1.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365135,964,796 - 135,965,627 (-)MPROMDB
RGD ID:6837698
Promoter ID:MM_KWN:44358
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_146001
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365136,020,881 - 136,021,632 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1099804 AgrOrtholog
Ensembl Genes ENSMUSG00000039959 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000060311 ENTREZGENE
  ENSMUST00000060311.12 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.1700 UniProtKB/Swiss-Prot
  1.25.40.90 UniProtKB/Swiss-Prot
  6.10.250.920 UniProtKB/Swiss-Prot
  I/LWEQ domain UniProtKB/Swiss-Prot
InterPro ANTH_dom UniProtKB/Swiss-Prot
  ENTH UniProtKB/Swiss-Prot
  ENTH_VHS UniProtKB/Swiss-Prot
  HIP1_clath-bd UniProtKB/Swiss-Prot
  I/LWEQ_dom_sf UniProtKB/Swiss-Prot
  ILWEQ_dom UniProtKB/Swiss-Prot
  Sla2_fam UniProtKB/Swiss-Prot
KEGG Report mmu:215114 UniProtKB/Swiss-Prot
MGD MGI:1099804 ENTREZGENE
NCBI Gene Hip1 ENTREZGENE
PANTHER PTHR10407 UniProtKB/Swiss-Prot
  PTHR10407:SF14 UniProtKB/Swiss-Prot
Pfam ANTH UniProtKB/Swiss-Prot
  HIP1_clath_bdg UniProtKB/Swiss-Prot
  I_LWEQ UniProtKB/Swiss-Prot
PhenoGen Hip1 PhenoGen
PROSITE ENTH UniProtKB/Swiss-Prot
  I_LWEQ UniProtKB/Swiss-Prot
SMART ENTH UniProtKB/Swiss-Prot
  ILWEQ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109885 UniProtKB/Swiss-Prot
  SSF48464 UniProtKB/Swiss-Prot
UniProt A0A0J9YUA3_MOUSE UniProtKB/TrEMBL
  A0A0J9YUX9_MOUSE UniProtKB/TrEMBL
  A0A0J9YV08_MOUSE UniProtKB/TrEMBL
  A0A1D5RMM7_MOUSE UniProtKB/TrEMBL
  HIP1_MOUSE UniProtKB/Swiss-Prot
  Q3TLS2 ENTREZGENE
  Q571K7 ENTREZGENE
  Q8C303_MOUSE UniProtKB/TrEMBL
  Q8VD75 ENTREZGENE
  Q9D1Z6_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q3TLS2 UniProtKB/Swiss-Prot
  Q571K7 UniProtKB/Swiss-Prot