Mmp16 (matrix metallopeptidase 16) - Rat Genome Database

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Gene: Mmp16 (matrix metallopeptidase 16) Mus musculus
Analyze
Symbol: Mmp16
Name: matrix metallopeptidase 16
RGD ID: 735918
MGI Page MGI
Description: Predicted to enable metalloaminopeptidase activity; metalloendopeptidase activity; and zinc ion binding activity. Acts upstream of or within chondrocyte proliferation; collagen catabolic process; and skeletal system morphogenesis. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; skin; and visual system. Orthologous to human MMP16 (matrix metallopeptidase 16).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: matrix metalloproteinase 16; matrix metalloproteinase-16; Membrane type 3-MMP; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase; MMP-16; MT-MMP 3; MT3-MM; MT3-MMP; Mt3mmp; MTMMP3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39417,853,072 - 18,117,479 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl417,852,893 - 18,119,145 (+)EnsemblGRCm39 Ensembl
GRCm38417,853,072 - 18,117,479 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl417,852,893 - 18,119,145 (+)EnsemblGRCm38mm10GRCm38
MGSCv37417,780,629 - 18,045,881 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36417,780,629 - 18,043,779 (+)NCBIMGSCv36mm8
Celera417,643,862 - 17,905,148 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map47.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP)
calcitriol  (ISO)
cefaloridine  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
coumestrol  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (EXP)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel sulfate  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium fluoride  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cartilage morphology  (IAGP)
abnormal chondrocyte morphology  (IAGP)
abnormal compact bone morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal eye morphology  (IEA)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone hypertrophic chondrocyte zone  (IAGP)
abnormal long bone morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal Meckel's cartilage morphology  (IAGP)
abnormal midface morphology  (IAGP)
abnormal parietal bone morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal vomer bone morphology  (IAGP)
absent bone trabeculae  (IAGP)
absent palatine bone  (IAGP)
cleft secondary palate  (IAGP)
decreased anxiety-related response  (IEA)
decreased body size  (IAGP)
decreased bone ossification  (IAGP)
decreased cranium length  (IAGP)
domed cranium  (IAGP)
frontal bone hypoplasia  (IAGP)
hyperactivity  (IEA)
hypoalgesia  (IEA)
increased mechanical nociceptive threshold  (IEA)
maxilla hypoplasia  (IAGP)
nasal bone hypoplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IEA)
palatal shelf hypoplasia  (IAGP)
palatal shelves fail to meet at midline  (IAGP)
parietal bone hypoplasia  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
pterygoid bone hypoplasia  (IAGP)
short femur  (IAGP)
short humerus  (IAGP)
short limbs  (IAGP)
short snout  (IAGP)
thin neurocranium  (IAGP)
vomer bone hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9653660   PMID:10349636   PMID:10949577   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11891989   PMID:12477932   PMID:15226265   PMID:15734845   PMID:15782199   PMID:15895410  
PMID:16141072   PMID:16141073   PMID:18022611   PMID:19542530   PMID:20858856   PMID:21267068   PMID:21677750   PMID:21768085   PMID:21873635   PMID:23421805   PMID:24194600   PMID:25794647  
PMID:27227700   PMID:27626380   PMID:29196321   PMID:30670377  


Genomics

Comparative Map Data
Mmp16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39417,853,072 - 18,117,479 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl417,852,893 - 18,119,145 (+)EnsemblGRCm39 Ensembl
GRCm38417,853,072 - 18,117,479 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl417,852,893 - 18,119,145 (+)EnsemblGRCm38mm10GRCm38
MGSCv37417,780,629 - 18,045,881 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36417,780,629 - 18,043,779 (+)NCBIMGSCv36mm8
Celera417,643,862 - 17,905,148 (+)NCBICelera
Cytogenetic Map4A3NCBI
cM Map47.08NCBI
MMP16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38888,032,011 - 88,327,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl888,032,011 - 88,328,025 (-)EnsemblGRCh38hg38GRCh38
GRCh37889,044,239 - 89,339,712 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36889,118,576 - 89,408,833 (-)NCBINCBI36Build 36hg18NCBI36
Build 34889,150,576 - 89,408,664NCBI
Celera885,244,102 - 85,534,339 (-)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef884,259,378 - 84,549,728 (-)NCBIHuRef
CHM1_1889,091,126 - 89,381,311 (-)NCBICHM1_1
T2T-CHM13v2.0889,155,362 - 89,450,838 (-)NCBIT2T-CHM13v2.0
Mmp16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2531,312,280 - 31,556,276 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl531,312,280 - 31,548,388 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx533,458,804 - 33,703,762 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0535,051,511 - 35,296,458 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0534,991,048 - 35,235,995 (+)NCBIRnor_WKY
Rnor_6.0531,568,344 - 31,818,368 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl531,568,419 - 31,810,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0536,239,463 - 36,484,341 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4532,352,311 - 32,586,469 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1532,352,489 - 32,586,648 (+)NCBI
Celera530,477,009 - 30,710,815 (+)NCBICelera
Cytogenetic Map5q13NCBI
Mmp16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554175,303,290 - 5,545,589 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554175,298,334 - 5,545,121 (-)NCBIChiLan1.0ChiLan1.0
MMP16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1880,982,570 - 81,272,589 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0884,736,752 - 85,026,711 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1886,693,022 - 86,983,028 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl886,701,882 - 86,982,518 (-)Ensemblpanpan1.1panPan2
MMP16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12933,896,133 - 34,207,560 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2933,917,907 - 34,207,466 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2934,056,176 - 34,360,687 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02934,093,268 - 34,403,773 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2934,120,818 - 34,403,822 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12934,106,198 - 34,398,221 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02934,114,566 - 34,418,869 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02934,536,488 - 34,840,936 (-)NCBIUU_Cfam_GSD_1.0
Mmp16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530345,246,022 - 45,504,496 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365442,298,028 - 2,546,689 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365442,297,698 - 2,546,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl448,556,967 - 48,862,985 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1448,556,826 - 48,867,959 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2453,295,213 - 53,606,489 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MMP16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1883,122,904 - 83,407,910 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl883,132,315 - 83,407,933 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603957,498,698 - 57,789,347 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247443,544,552 - 3,796,821 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247443,544,258 - 3,806,097 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mmp16
9291 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir146mmu-miR-146a-5pOncomiRDBexternal_infoNANA22348245
Mir146bmmu-miR-146b-5pOncomiRDBexternal_infoNANA19265686

Predicted Target Of
Summary Value
Count of predictions:1641
Count of miRNA genes:690
Interacting mature miRNAs:905
Transcripts:ENSMUST00000029881, ENSMUST00000133416, ENSMUST00000139418, ENSMUST00000142434, ENSMUST00000149353, ENSMUST00000183662
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11049579Lmr9b_mleishmaniasis resistance 9b (mouse)4120657234Mouse
11049580Lmr9a_mleishmaniasis resistance 9 (mouse)4120657234Mouse
1301274Lmr9_mleishmaniasis resistance 9 (mouse)Not determined4120657234Mouse
10412079Sm1_msusceptibility to Schistosoma mansoni infection 1 (mouse)Not determined4122955614Mouse
1301510Bbaa13_mB.burgdorferi-associated arthritis 13 (mouse)Not determined4126395649Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse

Markers in Region
RH134462  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38418,118,835 - 18,119,014UniSTSGRCm38
MGSCv37418,045,982 - 18,046,161UniSTSGRCm37
Celera417,905,249 - 17,905,428UniSTS
Cytogenetic Map4A3UniSTS
cM Map43.6UniSTS
Mmp16  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38417,853,693 - 17,853,783UniSTSGRCm38
MGSCv37417,780,840 - 17,780,930UniSTSGRCm37
Celera417,644,073 - 17,644,163UniSTS
Cytogenetic Map4A3UniSTS
cM Map43.6UniSTS
45.MHAa92d9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38417,938,997 - 17,939,190UniSTSGRCm38
MGSCv37417,866,144 - 17,866,337UniSTSGRCm37
Celera417,729,094 - 17,729,287UniSTS
Cytogenetic Map4A3UniSTS
cM Map43.6UniSTS
Whitehead_YAC4 UniSTS
D4Mit1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38417,892,616 - 17,892,734UniSTSGRCm38
MGSCv37417,819,763 - 17,819,881UniSTSGRCm37
Celera417,682,955 - 17,683,073UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map4A3UniSTS
cM Map46.3UniSTS
Whitehead Genetic48.7UniSTS
Whitehead/MRC_RH4299.55UniSTS
Whitehead_YAC4 UniSTS
AB021228  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38418,116,210 - 18,116,353UniSTSGRCm38
MGSCv37418,043,357 - 18,043,500UniSTSGRCm37
Celera417,902,624 - 17,902,767UniSTS
Cytogenetic Map4A3UniSTS
cM Map43.6UniSTS
Whitehead/MRC_RH4302.08UniSTS
MMP16_920  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38418,116,039 - 18,116,933UniSTSGRCm38
MGSCv37418,043,186 - 18,044,080UniSTSGRCm37
Celera417,902,453 - 17,903,347UniSTS
Cytogenetic Map4A3UniSTS
cM Map43.6UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001379518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001379519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_135158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_166735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB021228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF282844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL683877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB373714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB621117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN460527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM570999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000029881   ⟹   ENSMUSP00000029881
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl417,853,458 - 18,119,145 (+)Ensembl
GRCm38.p6 Ensembl417,853,458 - 18,119,145 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133416
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl417,853,593 - 18,054,681 (+)Ensembl
GRCm38.p6 Ensembl417,853,593 - 18,054,681 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139418
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl418,051,757 - 18,093,719 (+)Ensembl
GRCm38.p6 Ensembl418,051,757 - 18,093,719 (+)Ensembl
RefSeq Acc Id: ENSMUST00000142434   ⟹   ENSMUSP00000121087
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl417,853,091 - 17,996,293 (+)Ensembl
GRCm38.p6 Ensembl417,853,091 - 17,996,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149353   ⟹   ENSMUSP00000116930
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl417,933,991 - 18,011,695 (+)Ensembl
GRCm38.p6 Ensembl417,933,991 - 18,011,695 (+)Ensembl
RefSeq Acc Id: ENSMUST00000183662   ⟹   ENSMUSP00000139102
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl417,852,893 - 18,117,457 (+)Ensembl
GRCm38.p6 Ensembl417,852,893 - 18,117,457 (+)Ensembl
RefSeq Acc Id: NM_001379518   ⟹   NP_001366447
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39417,853,072 - 18,117,479 (+)NCBI
GRCm38417,853,072 - 18,117,479 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001379519   ⟹   NP_001366448
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39417,853,292 - 18,117,479 (+)NCBI
GRCm38417,853,292 - 18,117,479 (+)NCBI
Sequence:
RefSeq Acc Id: NM_019724   ⟹   NP_062698
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39417,853,465 - 18,117,479 (+)NCBI
GRCm38417,853,465 - 18,117,479 (+)NCBI
MGSCv37417,780,629 - 18,045,881 (+)RGD
Celera417,643,862 - 17,905,148 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_135158
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39417,853,072 - 18,117,479 (+)NCBI
GRCm38417,853,072 - 18,117,479 (+)NCBI
Sequence:
RefSeq Acc Id: NR_166735
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39417,853,292 - 18,117,479 (+)NCBI
GRCm38417,853,292 - 18,117,479 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062698   ⟸   NM_019724
- Peptide Label: preproprotein
- UniProtKB: Q9ERT6 (UniProtKB/Swiss-Prot),   Q9WTR0 (UniProtKB/Swiss-Prot),   A0A6P7R3H7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001366447   ⟸   NM_001379518
- Peptide Label: preproprotein
- UniProtKB: Q9ERT6 (UniProtKB/Swiss-Prot),   A0A6P7R3H7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001366448   ⟸   NM_001379519
- Peptide Label: preproprotein
- UniProtKB: Q9ERT6 (UniProtKB/Swiss-Prot),   A0A6P7R3H7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000139102   ⟸   ENSMUST00000183662
RefSeq Acc Id: ENSMUSP00000029881   ⟸   ENSMUST00000029881
RefSeq Acc Id: ENSMUSP00000116930   ⟸   ENSMUST00000149353
RefSeq Acc Id: ENSMUSP00000121087   ⟸   ENSMUST00000142434
Protein Domains
Peptidase M10 metallopeptidase   Peptidase M10A matrix metallopeptidase C-terminal   Peptidase metallopeptidase   Peptidoglycan binding-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WTR0-F1-model_v2 AlphaFold Q9WTR0 1-607 view protein structure

Promoters
RGD ID:6835717
Promoter ID:MM_KWN:36783
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000010497,   OTTMUST00000010498,   OTTMUST00000010500,   UC008SBV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36417,780,286 - 17,780,786 (+)MPROMDB
RGD ID:6882886
Promoter ID:EPDNEW_M4894
Type:initiation region
Name:Mmp16_1
Description:Mus musculus matrix metallopeptidase 16 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38417,853,465 - 17,853,525EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1276107 AgrOrtholog
Ensembl Genes ENSMUSG00000028226 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000029881 ENTREZGENE
  ENSMUSP00000029881.4 UniProtKB/Swiss-Prot
  ENSMUSP00000116930.2 UniProtKB/TrEMBL
  ENSMUSP00000121087.2 UniProtKB/TrEMBL
  ENSMUSP00000139102.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029881 ENTREZGENE
  ENSMUST00000029881.10 UniProtKB/Swiss-Prot
  ENSMUST00000142434.8 UniProtKB/TrEMBL
  ENSMUST00000149353.2 UniProtKB/TrEMBL
  ENSMUST00000183662 ENTREZGENE
  ENSMUST00000183662.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.101.10 UniProtKB/TrEMBL
  2.110.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M10A_MMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A_metallopeptidase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBDSf UniProtKB/TrEMBL
KEGG Report mmu:17389 UniProtKB/Swiss-Prot
MGD MGI:1276107 ENTREZGENE
NCBI Gene 17389 ENTREZGENE
PANTHER EG:8D8.2 PROTEIN-RELATED UniProtKB/TrEMBL
  HEMOPEXIN DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10201:SF26 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF3377 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mmp16 PhenoGen
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOPEXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART SM00120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47090 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A6P7R3H7 ENTREZGENE
  B1AVG8_MOUSE UniProtKB/TrEMBL
  B1AVH0_MOUSE UniProtKB/TrEMBL
  MMP16_MOUSE UniProtKB/Swiss-Prot
  Q8BSA6_MOUSE UniProtKB/TrEMBL
  Q9ERT6 ENTREZGENE
  Q9WTR0 ENTREZGENE
  V9GXD8_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q6PEQ6 UniProtKB/Swiss-Prot
  Q9ERT6 UniProtKB/Swiss-Prot