Prodh (proline dehydrogenase) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Prodh (proline dehydrogenase) Mus musculus
Analyze
Symbol: Prodh
Name: proline dehydrogenase
RGD ID: 735636
MGI Page MGI
Description: Predicted to enable FAD binding activity; amino acid binding activity; and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate and regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway. Predicted to act upstream of or within proline metabolic process. Located in mitochondrion. Is expressed in several structures, including adipose tissue; cardiovascular system; central nervous system; forelimb bud; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC159030; P; Pr; Pro-1; Pro1; proline dehydrogenase 1, mitochondrial; proline dehydrogenase, mitochondrial; proline oxidase; Ym24d07
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,889,593 - 17,907,147 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,878,221 - 17,908,067 (-)EnsemblGRCm39 Ensembl
GRCm381618,071,726 - 18,089,283 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,060,357 - 18,090,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371618,071,819 - 18,089,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361617,985,289 - 18,002,710 (-)NCBIMGSCv36mm8
Celera1618,644,311 - 18,661,775 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
aripiprazole  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[k]fluoranthene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (EXP)
chloroprene  (EXP)
ciglitazone  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diquat  (EXP)
disodium selenite  (ISO)
dizocilpine maleate  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fenofibrate  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
glafenine  (ISO)
indometacin  (ISO)
isoprenaline  (EXP)
methamphetamine  (EXP)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
mifepristone  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
nimesulide  (ISO)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
ozone  (EXP)
p-menthan-3-ol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP)
prostaglandin E2  (ISO)
reactive oxygen species  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sotorasib  (ISO)
sulfadimethoxine  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thioacetamide  (ISO)
trametinib  (ISO)
triadimefon  (ISO)
triclosan  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The gene encoding proline dehydrogenase modulates sensorimotor gating in mice. Gogos JA, etal., Nat Genet 1999 Apr;21(4):434-9.
2. PRODH mutations and hyperprolinemia in a subset of schizophrenic patients. Jacquet H, etal., Hum Mol Genet. 2002 Sep 15;11(19):2243-9.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1008803   PMID:1055415   PMID:5031477   PMID:8889548   PMID:10337614   PMID:10349636   PMID:10704284   PMID:10767319   PMID:10963672   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:12477932   PMID:12819125   PMID:12865426   PMID:14610273   PMID:14614146   PMID:14681479   PMID:15581617   PMID:16141072   PMID:16141073   PMID:16234811   PMID:16602821   PMID:17097888  
PMID:18614015   PMID:18775783   PMID:18799693   PMID:19805316   PMID:21267068   PMID:21677750   PMID:21821099   PMID:21873635   PMID:22323595   PMID:23055483   PMID:23077214   PMID:24194600  
PMID:24357327   PMID:24952961   PMID:25452572   PMID:26660760   PMID:27626380   PMID:27705802   PMID:28685754   PMID:38355793  


Genomics

Comparative Map Data
Prodh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,889,593 - 17,907,147 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1617,878,221 - 17,908,067 (-)EnsemblGRCm39 Ensembl
GRCm381618,071,726 - 18,089,283 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,060,357 - 18,090,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371618,071,819 - 18,089,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361617,985,289 - 18,002,710 (-)NCBIMGSCv36mm8
Celera1618,644,311 - 18,661,775 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.19NCBI
PRODH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,912,781 - 18,936,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,912,777 - 18,936,553 (-)EnsemblGRCh38hg38GRCh38
GRCh372218,900,294 - 18,924,066 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,280,295 - 17,304,066 (-)NCBINCBI36Build 36hg18NCBI36
Build 342217,274,848 - 17,298,620NCBI
Celera222,752,487 - 2,775,952 (-)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef222,522,549 - 2,546,463 (-)NCBIHuRef
CHM1_12218,900,046 - 18,923,816 (-)NCBICHM1_1
T2T-CHM13v2.02219,288,173 - 19,311,947 (-)NCBIT2T-CHM13v2.0
Prodh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81196,414,275 - 96,431,604 (+)NCBIGRCr8
mRatBN7.21182,910,043 - 82,927,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,910,137 - 82,927,305 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,638,491 - 91,655,681 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01184,299,609 - 84,316,799 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01183,353,230 - 83,370,416 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,058,478 - 87,075,785 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,058,616 - 87,075,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,150,469 - 90,167,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,905,060 - 84,922,229 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1181,685,816 - 81,702,985 (+)NCBICelera
Cytogenetic Map11q23NCBI
PRODH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,539,527 - 28,563,800 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,087,140 - 31,111,607 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0221,654,019 - 1,678,389 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,351,283 - 17,376,108 (-)NCBIpanpan1.1PanPan1.1panPan2
LOC477562
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,039,007 - 29,059,722 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2628,998,409 - 29,019,789 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02630,442,109 - 30,463,491 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12628,490,997 - 28,512,379 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,116,817 - 28,138,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,201,167 - 29,222,548 (-)NCBIUU_Cfam_GSD_1.0
LOC110256626
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11451,624,919 - 51,644,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2035
Count of miRNA genes:716
Interacting mature miRNAs:896
Transcripts:ENSMUST00000003620, ENSMUST00000123969, ENSMUST00000126087, ENSMUST00000132241, ENSMUST00000136776, ENSMUST00000139861, ENSMUST00000141635
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124263853Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122500574Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16122897739Mouse
15092082Igly9_mIgG glycosylation 9, GP17b (mouse)161477522320103513Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124263853Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120780888Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122520318Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
RH124940  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381618,077,842 - 18,079,247UniSTSGRCm38
MGSCv371618,077,935 - 18,079,340UniSTSGRCm37
Celera1618,650,427 - 18,651,832UniSTS
Cytogenetic Map16A3UniSTS
cM Map1610.73UniSTS
Prodh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381618,072,264 - 18,072,484UniSTSGRCm38
MGSCv371618,072,357 - 18,072,577UniSTSGRCm37
Celera1618,644,849 - 18,645,069UniSTS
Cytogenetic Map16A3UniSTS
cM Map1610.73UniSTS
Prodh  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16A3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000003620   ⟹   ENSMUSP00000003620
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,889,589 - 17,907,156 (-)Ensembl
GRCm38.p6 Ensembl1618,071,725 - 18,089,292 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123969
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,889,589 - 17,900,183 (-)Ensembl
GRCm38.p6 Ensembl1618,071,725 - 18,082,319 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126087   ⟹   ENSMUSP00000121736
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,890,120 - 17,897,806 (-)Ensembl
GRCm38.p6 Ensembl1618,072,256 - 18,079,942 (-)Ensembl
Ensembl Acc Id: ENSMUST00000132241   ⟹   ENSMUSP00000118264
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,902,068 - 17,906,886 (-)Ensembl
GRCm38.p6 Ensembl1618,084,204 - 18,089,022 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136776   ⟹   ENSMUSP00000117597
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,889,590 - 17,908,067 (-)Ensembl
GRCm38.p6 Ensembl1618,071,726 - 18,090,203 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139861   ⟹   ENSMUSP00000123223
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,878,221 - 17,907,027 (-)Ensembl
GRCm38.p6 Ensembl1618,060,357 - 18,089,163 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141635   ⟹   ENSMUSP00000122889
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,889,990 - 17,897,132 (-)Ensembl
GRCm38.p6 Ensembl1618,072,126 - 18,079,268 (-)Ensembl
Ensembl Acc Id: ENSMUST00000232384
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,894,253 - 17,898,112 (-)Ensembl
GRCm38.p6 Ensembl1618,076,389 - 18,080,248 (-)Ensembl
Ensembl Acc Id: ENSMUST00000232502
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,902,065 - 17,907,007 (-)Ensembl
GRCm38.p6 Ensembl1618,084,201 - 18,089,143 (-)Ensembl
Ensembl Acc Id: ENSMUST00000232554   ⟹   ENSMUSP00000156221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1617,890,382 - 17,897,086 (-)Ensembl
GRCm38.p6 Ensembl1618,072,518 - 18,079,222 (-)Ensembl
RefSeq Acc Id: NM_011172   ⟹   NP_035302
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,889,593 - 17,907,026 (-)NCBI
GRCm381618,071,726 - 18,089,190 (-)NCBI
MGSCv371618,071,819 - 18,089,283 (-)RGD
Celera1618,644,311 - 18,661,775 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_189733
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,889,593 - 17,907,026 (-)NCBI
RefSeq Acc Id: XM_006521863   ⟹   XP_006521926
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,891,497 - 17,907,147 (-)NCBI
GRCm381618,073,633 - 18,089,283 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001781795
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,891,456 - 17,907,147 (-)NCBI
GRCm381618,073,592 - 18,089,283 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035302   ⟸   NM_011172
- Peptide Label: precursor
- UniProtKB: Q3UNR4 (UniProtKB/Swiss-Prot),   A0JLW6 (UniProtKB/Swiss-Prot),   Q9QX61 (UniProtKB/Swiss-Prot),   Q9WU79 (UniProtKB/Swiss-Prot),   A0A0R4J1T9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521926   ⟸   XM_006521863
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000123223   ⟸   ENSMUST00000139861
Ensembl Acc Id: ENSMUSP00000118264   ⟸   ENSMUST00000132241
Ensembl Acc Id: ENSMUSP00000121736   ⟸   ENSMUST00000126087
Ensembl Acc Id: ENSMUSP00000003620   ⟸   ENSMUST00000003620
Ensembl Acc Id: ENSMUSP00000156221   ⟸   ENSMUST00000232554
Ensembl Acc Id: ENSMUSP00000117597   ⟸   ENSMUST00000136776
Ensembl Acc Id: ENSMUSP00000122889   ⟸   ENSMUST00000141635
Protein Domains
Proline dehydrogenase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WU79-F1-model_v2 AlphaFold Q9WU79 1-599 view protein structure

Promoters
RGD ID:6827384
Promoter ID:MM_KWN:20352
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Spleen
Transcripts:OTTMUST00000069802
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361618,079,151 - 18,080,157 (-)MPROMDB
RGD ID:6827381
Promoter ID:MM_KWN:20353
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000069801
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361618,080,506 - 18,081,006 (-)MPROMDB
RGD ID:6827379
Promoter ID:MM_KWN:20354
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000069800
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361618,082,556 - 18,083,382 (-)MPROMDB
RGD ID:6827380
Promoter ID:MM_KWN:20355
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000069797,   OTTMUST00000069798,   UC007YMS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361618,089,026 - 18,089,526 (-)MPROMDB
RGD ID:8685654
Promoter ID:EPDNEW_M20858
Type:single initiation site
Name:Prodh_1
Description:Mus musculus proline dehydrogenase , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381618,089,162 - 18,089,222EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97770 AgrOrtholog
Ensembl Genes ENSMUSG00000003526 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000003620 ENTREZGENE
  ENSMUST00000003620.13 UniProtKB/Swiss-Prot
  ENSMUST00000126087.2 UniProtKB/TrEMBL
  ENSMUST00000132241.2 UniProtKB/TrEMBL
  ENSMUST00000136776.8 UniProtKB/TrEMBL
  ENSMUST00000139861.2 UniProtKB/TrEMBL
  ENSMUST00000141635.8 UniProtKB/TrEMBL
  ENSMUST00000232554.2 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FAD-linked_oxidoreductase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proline_DH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proline_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19125 UniProtKB/Swiss-Prot
MGD MGI:97770 ENTREZGENE
NCBI Gene 19125 ENTREZGENE
PANTHER PROLINE DEHYDROGENASE 1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13914 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pro_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prodh PhenoGen
Superfamily-SCOP SSF51730 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1T9 ENTREZGENE, UniProtKB/TrEMBL
  A0A338P738_MOUSE UniProtKB/TrEMBL
  A0JLW6 ENTREZGENE
  E9PUR5_MOUSE UniProtKB/TrEMBL
  F6PYI8_MOUSE UniProtKB/TrEMBL
  F6XMC0_MOUSE UniProtKB/TrEMBL
  F6YFQ5_MOUSE UniProtKB/TrEMBL
  PROD_MOUSE UniProtKB/Swiss-Prot
  Q3UNR4 ENTREZGENE
  Q8C3G7_MOUSE UniProtKB/TrEMBL
  Q9QX61 ENTREZGENE
  Q9WU79 ENTREZGENE
UniProt Secondary A0JLW6 UniProtKB/Swiss-Prot
  Q3UNR4 UniProtKB/Swiss-Prot
  Q9QX61 UniProtKB/Swiss-Prot