NOS3 (nitric oxide synthase 3) - Rat Genome Database

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Gene: NOS3 (nitric oxide synthase 3) Homo sapiens
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Symbol: NOS3
Name: nitric oxide synthase 3
RGD ID: 735618
HGNC Page HGNC:7876
Description: Enables several functions, including actin monomer binding activity; arginine binding activity; and heme binding activity. Involved in several processes, including nitric oxide biosynthetic process; positive regulation of guanylate cyclase activity; and removal of superoxide radicals. Located in Golgi apparatus and caveola. Implicated in several diseases, including artery disease (multiple); eye disease (multiple); leukemia (multiple); reproductive organ cancer (multiple); and vasculitis (multiple). Biomarker of several diseases, including central sleep apnea; endometrial carcinoma; lymphangioleiomyomatosis; obstructive sleep apnea; and pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cNOS; constitutive NOS; EC-NOS; ECNOS; endothelial NOS; eNOS; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 [endothelial cell]; nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS type III; NOSIII
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Candidate Gene For: BW383_H BW384_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387150,991,017 - 151,014,588 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7150,991,017 - 151,014,588 (+)EnsemblGRCh38hg38GRCh38
GRCh377150,688,105 - 150,711,676 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,319,080 - 150,342,609 (+)NCBINCBI36Build 36hg18NCBI36
Build 347150,125,794 - 150,149,323NCBI
Celera7145,245,139 - 145,269,020 (+)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7144,500,690 - 144,524,025 (+)NCBIHuRef
CHM1_17150,696,541 - 150,720,093 (+)NCBICHM1_1
T2T-CHM13v2.07152,163,824 - 152,187,711 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,017,398 - 150,041,276 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model