LDHB (lactate dehydrogenase B) - Rat Genome Database

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Advanced Search (OLGA)
Gene: LDHB (lactate dehydrogenase B) Homo sapiens
Analyze
Symbol: LDHB
Name: lactate dehydrogenase B
RGD ID: 735463
HGNC Page HGNC:6541
Description: Enables L-lactate dehydrogenase activity and identical protein binding activity. Involved in lactate metabolic process and pyruvate metabolic process. Located in cytosol; membrane raft; and mitochondrial inner membrane. Part of oxidoreductase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: epididymis secretory protein Li 281; HEL-S-281; L-lactate dehydrogenase B chain; lactate dehydrogenase H chain; LDH heart subunit; LDH-B; LDH-H; LDHBD; renal carcinoma antigen NY-REN-46; testicular secretory protein Li 25; TRG-5
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: LDHBP1   LDHBP2   LDHBP3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,635,342 - 21,657,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,635,342 - 21,757,857 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,788,276 - 21,810,776 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,679,543 - 21,702,043 (-)NCBINCBI36Build 36hg18NCBI36
Build 341221,679,544 - 21,702,042NCBI
Celera1226,943,264 - 26,965,789 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,561,869 - 21,584,405 (-)NCBIHuRef
CHM1_11221,753,523 - 21,776,056 (-)NCBICHM1_1
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R,R)-alpha-tocopherol  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2,2-tetramine  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (EXP)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (EXP)
7H-xanthine  (ISO)
9H-xanthine  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
aristolochic acid A  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-lapachone  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
Bisphenol B  (EXP)
bisphenol F  (EXP,ISO)
Brodifacoum  (ISO)
bromobenzene  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
casticin  (EXP)
chlorite  (EXP)
chloropicrin  (EXP)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cis-caffeic acid  (ISO)
clozapine  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (EXP)
D-glucose  (EXP)
DDE  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP)
dihydroartemisinin  (EXP)
dihydroxyacetone  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP)
diuron  (ISO)
doxorubicin  (EXP)
endosulfan  (ISO)
enzyme inhibitor  (EXP)
ethanol  (ISO)
fenofibrate  (EXP)
folic acid  (ISO)
fructose  (ISO)
fulvestrant  (EXP)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP)
glucose  (EXP)
haloperidol  (ISO)
heparin  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
ibuprofen  (EXP)
indometacin  (ISO)
isoprenaline  (ISO)
ivermectin  (EXP)
ketamine  (ISO)
L-methionine  (ISO)
lanthanum trichloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
Monobutylphthalate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naphthalene  (ISO)
naringin  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylpropanolamine  (ISO)
picrotoxin  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
rotenone  (EXP)
serpentine asbestos  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sodium nitrite  (EXP)
Soman  (ISO)
streptozocin  (ISO)
tamoxifen  (ISO)
tanespimycin  (EXP)
Tesaglitazar  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
toxaphene  (ISO)
trans-caffeic acid  (ISO)
triphenylstannane  (EXP)
troglitazone  (EXP,ISO)
valproic acid  (EXP)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,TAS)
cytosol  (IDA,IEA,TAS)
extracellular exosome  (HDA)
membrane  (HDA,IEA)
membrane raft  (IDA)
mitochondrial inner membrane  (IDA,IEA)
mitochondrion  (IBA,IEA)
oxidoreductase complex  (IPI,ISS)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
Additional References at PubMed
PMID:477403   PMID:1081369   PMID:1371976   PMID:1587525   PMID:1996957   PMID:2334429   PMID:2930497   PMID:3435492   PMID:7273846   PMID:7821789   PMID:8314553   PMID:8462975  
PMID:8611651   PMID:9929983   PMID:10211631   PMID:10508479   PMID:10509905   PMID:11125887   PMID:11276087   PMID:11509017   PMID:11582518   PMID:11726686   PMID:12160330   PMID:12477932  
PMID:12555229   PMID:15117937   PMID:15489334   PMID:15492215   PMID:15592455   PMID:15710247   PMID:16130169   PMID:16236267   PMID:17178662   PMID:18457437   PMID:18593994   PMID:19056867  
PMID:19135240   PMID:19338310   PMID:19738201   PMID:19786724   PMID:19946888   PMID:20000738   PMID:20458337   PMID:20499337   PMID:20592382   PMID:20877624   PMID:20951115   PMID:21044950  
PMID:21081503   PMID:21145461   PMID:21199794   PMID:21319273   PMID:21356207   PMID:21516116   PMID:21653829   PMID:21858537   PMID:21873635   PMID:21988832   PMID:22027740   PMID:22248949  
PMID:22304920   PMID:22461886   PMID:22623428   PMID:22752059   PMID:22807456   PMID:22863883   PMID:22891270   PMID:22892192   PMID:22939629   PMID:22990118   PMID:23125841   PMID:23139210  
PMID:23166591   PMID:23184937   PMID:23202721   PMID:23224736   PMID:23246001   PMID:23266049   PMID:23349634   PMID:23376485   PMID:23437403   PMID:23508102   PMID:23516535   PMID:23533145  
PMID:23697991   PMID:23703029   PMID:24457600   PMID:24682390   PMID:24708595   PMID:24725412   PMID:24999758   PMID:25147182   PMID:25192599   PMID:25204797   PMID:25247702   PMID:25315684  
PMID:25340584   PMID:25416956   PMID:25458010   PMID:25502805   PMID:25505242   PMID:25524555   PMID:25910212   PMID:25921289   PMID:25940091   PMID:25959826   PMID:25963833   PMID:25973606  
PMID:26032856   PMID:26214432   PMID:26344197   PMID:26472760   PMID:26496610   PMID:26499835   PMID:26561776   PMID:26577856   PMID:26618866   PMID:26693507   PMID:26760575   PMID:26816005  
PMID:26831064   PMID:26885983   PMID:27025967   PMID:27107014   PMID:27182664   PMID:27485076   PMID:27618187   PMID:27622334   PMID:27684187   PMID:27732843   PMID:28186131   PMID:28302793  
PMID:28443643   PMID:28514442   PMID:28515276   PMID:28524877   PMID:28581483   PMID:28756978   PMID:28775156   PMID:28890335   PMID:29117863   PMID:29128334   PMID:29229926   PMID:29298432  
PMID:29331416   PMID:29395067   PMID:29449217   PMID:29467282   PMID:29507755   PMID:29845934   PMID:29891507   PMID:29911972   PMID:30158244   PMID:30425250   PMID:30442662   PMID:30443978  
PMID:30455355   PMID:30463901   PMID:30610122   PMID:30711629   PMID:30884312   PMID:30923124   PMID:30948266   PMID:30976022   PMID:31091453   PMID:31180492   PMID:31239290   PMID:31300519  
PMID:31405213   PMID:31424671   PMID:31436131   PMID:31501420   PMID:31515488   PMID:31536960   PMID:31586073   PMID:31796584   PMID:31839598   PMID:31995728   PMID:32129710   PMID:32203420  
PMID:32249768   PMID:32296183   PMID:32432403   PMID:32529326   PMID:32552912   PMID:32572027   PMID:32687490   PMID:32694731   PMID:32707033   PMID:32807901   PMID:32814053   PMID:32859627  
PMID:32905556   PMID:32929329   PMID:32963011   PMID:32994395   PMID:33024031   PMID:33306668   PMID:33325062   PMID:33406399   PMID:33565425   PMID:33567341   PMID:33729478   PMID:33742100  
PMID:33762435   PMID:33863777   PMID:33916271   PMID:33947761   PMID:33961781   PMID:34017080   PMID:34022218   PMID:34079125   PMID:34158867   PMID:34189442   PMID:34349018   PMID:34428256  
PMID:34478437   PMID:34597346   PMID:34708888   PMID:34709727   PMID:34728620   PMID:34732716   PMID:34780483   PMID:34901782   PMID:35063084   PMID:35235311   PMID:35256949   PMID:35271311  
PMID:35356984   PMID:35446349   PMID:35509820   PMID:35562734   PMID:35563538   PMID:35605301   PMID:35676659   PMID:35794505   PMID:35831314   PMID:35831895   PMID:35844135   PMID:35850772  
PMID:36030824   PMID:36055981   PMID:36057605   PMID:36199071   PMID:36215168   PMID:36217030   PMID:36225252   PMID:36273042   PMID:36282215   PMID:36339263   PMID:36373674   PMID:36517590  
PMID:36526897   PMID:36543142   PMID:36574265   PMID:36652389   PMID:36762613   PMID:37059091   PMID:37071682   PMID:37108203   PMID:37120454   PMID:37167062   PMID:37223481   PMID:37232246  
PMID:37314216   PMID:37317656   PMID:37536630   PMID:37547725   PMID:37667382   PMID:37689310   PMID:37820061   PMID:37827155   PMID:38048029   PMID:38113892   PMID:38172120   PMID:38245532  
PMID:38334954   PMID:38569033   PMID:38580884   PMID:38607916   PMID:38697112   PMID:38702940   PMID:38739169   PMID:38994005   PMID:39147351   PMID:39358380   PMID:39422127  


Genomics

Comparative Map Data
LDHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,635,342 - 21,657,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1221,635,342 - 21,757,857 (-)EnsemblGRCh38hg38GRCh38
GRCh371221,788,276 - 21,810,776 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,679,543 - 21,702,043 (-)NCBINCBI36Build 36hg18NCBI36
Build 341221,679,544 - 21,702,042NCBI
Celera1226,943,264 - 26,965,789 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1221,561,869 - 21,584,405 (-)NCBIHuRef
CHM1_11221,753,523 - 21,776,056 (-)NCBICHM1_1
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBIT2T-CHM13v2.0
Ldhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,435,975 - 142,453,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,435,975 - 142,453,683 (-)EnsemblGRCm39 Ensembl
GRCm386142,490,249 - 142,507,957 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,490,249 - 142,507,957 (-)EnsemblGRCm38mm10GRCm38
MGSCv376142,438,769 - 142,456,463 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366142,447,471 - 142,465,165 (-)NCBIMGSCv36mm8
Celera6145,551,908 - 145,569,602 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map674.17NCBI
Ldhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,159,389 - 177,177,408 (-)NCBIGRCr8
mRatBN7.24175,428,382 - 175,446,403 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,428,385 - 175,446,403 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4181,723,217 - 181,741,234 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,507,488 - 177,525,505 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,128,058 - 176,146,075 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04176,701,980 - 176,719,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4176,701,983 - 176,720,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04240,918,027 - 240,936,014 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44180,061,567 - 180,079,473 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14180,306,690 - 180,322,406 (-)NCBI
Celera4163,963,498 - 163,981,517 (-)NCBICelera
Cytogenetic Map4q44NCBI
Ldhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,261,118 - 17,283,593 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541317,264,337 - 17,283,530 (-)NCBIChiLan1.0ChiLan1.0
LDHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21075,145,106 - 75,167,533 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11275,141,504 - 75,163,931 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01264,640,994 - 64,663,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11267,245,012 - 67,267,487 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1267,245,130 - 67,267,487 (+)Ensemblpanpan1.1panPan2
LDHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12725,470,666 - 25,493,114 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2725,470,665 - 25,492,920 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2720,864,321 - 20,886,793 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02725,693,648 - 25,716,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,693,609 - 25,716,160 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12725,492,290 - 25,514,750 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02725,515,724 - 25,538,195 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02721,035,083 - 21,057,566 (-)NCBIUU_Cfam_GSD_1.0
Ldhb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494587,301,989 - 87,321,822 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365485,227,666 - 5,244,525 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365485,224,905 - 5,244,708 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LDHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1551,810,932 - 51,831,218 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2555,086,895 - 55,106,892 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LDHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11121,489,815 - 21,511,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1121,488,814 - 21,511,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606913,631,514 - 13,654,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ldhb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475217,049,296 - 17,069,553 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475217,046,640 - 17,065,910 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LDHB
48 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002300.8(LDHB):c.515G>A (p.Arg172His) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000015663] Chr12:21642032 [GRCh38]
Chr12:21794966 [GRCh37]
Chr12:12p12.1		 pathogenic|affects
NM_002300.8(LDHB):c.385A>C (p.Ser129Arg) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000015664] Chr12:21643971 [GRCh38]
Chr12:21796905 [GRCh37]
Chr12:12p12.1		 pathogenic|affects
NM_002300.8(LDHB):c.19A>G (p.Lys7Glu) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000015665] Chr12:21654653 [GRCh38]
Chr12:21807587 [GRCh37]
Chr12:12p12.1		 pathogenic|affects
NM_002300.8(LDHB):c.973T>C (p.Trp325Arg) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000015666] Chr12:21635574 [GRCh38]
Chr12:21788508 [GRCh37]
Chr12:12p12.1		 pathogenic|affects
GRCh38/hg38 12p13.33-11.22(chr12:121055-28415184)x1 copy number loss See cases [RCV000052776] Chr12:121055..28415184 [GRCh38]
Chr12:282465..28568117 [GRCh37]
Chr12:100482..28459384 [NCBI36]
Chr12:12p13.33-11.22		 pathogenic
GRCh38/hg38 12p12.3-11.23(chr12:19295848-27012560)x1 copy number loss See cases [RCV000052782] Chr12:19295848..27012560 [GRCh38]
Chr12:19448782..27165493 [GRCh37]
Chr12:19340049..27056760 [NCBI36]
Chr12:12p12.3-11.23		 pathogenic
GRCh38/hg38 12p13.33-12.1(chr12:80412-25470329)x3 copy number gain See cases [RCV000053662] Chr12:80412..25470329 [GRCh38]
Chr12:282465..25623263 [GRCh37]
Chr12:59839..25514530 [NCBI36]
Chr12:12p13.33-12.1		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:212976-33926913)x4 copy number gain See cases [RCV000053666] Chr12:212976..33926913 [GRCh38]
Chr12:322142..34079848 [GRCh37]
Chr12:192403..33971115 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh38/hg38 12p12.3-12.1(chr12:18252085-25696258)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053670]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053670]|See cases [RCV000053670] Chr12:18252085..25696258 [GRCh38]
Chr12:18405019..25849192 [GRCh37]
Chr12:18296286..25740459 [NCBI36]
Chr12:12p12.3-12.1		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:77187-34380176)x3 copy number gain See cases [RCV000053660] Chr12:77187..34380176 [GRCh38]
Chr12:282465..34533111 [GRCh37]
Chr12:56614..34424378 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh38/hg38 12p12.3-12.1(chr12:19265334-25482589)x1 copy number loss See cases [RCV000135588] Chr12:19265334..25482589 [GRCh38]
Chr12:19418268..25635523 [GRCh37]
Chr12:19309535..25526790 [NCBI36]
Chr12:12p12.3-12.1		 likely pathogenic
GRCh38/hg38 12p12.3-12.1(chr12:15840854-22021652)x1 copy number loss See cases [RCV000135620] Chr12:15840854..22021652 [GRCh38]
Chr12:15993788..22174586 [GRCh37]
Chr12:15885055..22065853 [NCBI36]
Chr12:12p12.3-12.1		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121255-34603274)x3 copy number gain See cases [RCV000136611] Chr12:121255..34603274 [GRCh38]
Chr12:282465..34756209 [GRCh37]
Chr12:100682..34647476 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121271-34603261)x3 copy number gain See cases [RCV000139052] Chr12:121271..34603261 [GRCh38]
Chr12:282465..34756196 [GRCh37]
Chr12:100698..34647463 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:54427-34608071)x4 copy number gain See cases [RCV000139787] Chr12:54427..34608071 [GRCh38]
Chr12:282465..34761006 [GRCh37]
Chr12:33854..34652273 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:64620-34682902)x4 copy number gain See cases [RCV000142149] Chr12:64620..34682902 [GRCh38]
Chr12:173786..34835837 [GRCh37]
Chr12:44047..34727104 [NCBI36]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:148034-34178799)x4 copy number gain See cases [RCV000240164] Chr12:148034..34178799 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic|likely pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:89061-34178799)x3 copy number gain See cases [RCV000240487] Chr12:89061..34178799 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
NM_002300.7(LDHB):c.-102C>A single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000282511] Chr12:21657846 [GRCh38]
Chr12:21810780 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.749A>G (p.Asn250Ser) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000303242]|not specified [RCV004021537] Chr12:21637159 [GRCh38]
Chr12:21790093 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.-81G>C single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000374638] Chr12:21657825 [GRCh38]
Chr12:21810759 [GRCh37]
Chr12:12p12.1		 benign|likely benign
NM_002300.8(LDHB):c.713+15A>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000306605]|not provided [RCV004708252] Chr12:21638338 [GRCh38]
Chr12:21791272 [GRCh37]
Chr12:12p12.1		 benign
NM_002300.8(LDHB):c.585C>T (p.Gly195=) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000271127] Chr12:21641962 [GRCh38]
Chr12:21794896 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.375C>T (p.Ile125=) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000389088] Chr12:21643981 [GRCh38]
Chr12:21796915 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.130-3_130-2del deletion Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000278311]|not provided [RCV000948885] Chr12:21647018..21647019 [GRCh38]
Chr12:21799952..21799953 [GRCh37]
Chr12:12p12.1		 benign|likely benign
NM_002300.8(LDHB):c.621G>T (p.Val207=) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000363662] Chr12:21638445 [GRCh38]
Chr12:21791379 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.472C>T (p.Arg158Cys) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000366792]|LDHB-related disorder [RCV003950045] Chr12:21642075 [GRCh38]
Chr12:21795009 [GRCh37]
Chr12:12p12.1		 likely benign|uncertain significance
NM_002300.8(LDHB):c.879A>G (p.Pro293=) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000393958]|not provided [RCV000886445] Chr12:21635668 [GRCh38]
Chr12:21788602 [GRCh37]
Chr12:12p12.1		 benign|likely benign
NM_002300.8(LDHB):c.422-10A>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000274571] Chr12:21642135 [GRCh38]
Chr12:21795069 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.719A>G (p.Tyr240Cys) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000404219] Chr12:21637189 [GRCh38]
Chr12:21790123 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.421+7T>C single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000332159] Chr12:21643928 [GRCh38]
Chr12:21796862 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.727A>G (p.Ile243Val) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000360135] Chr12:21637181 [GRCh38]
Chr12:21790115 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.129+11A>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000317035] Chr12:21654532 [GRCh38]
Chr12:21807466 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.*73T>C single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000338329] Chr12:21635469 [GRCh38]
Chr12:21788403 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.7(LDHB):c.-109C>T single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000339890] Chr12:21657853 [GRCh38]
Chr12:21810787 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.528T>A (p.Ala176=) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000328482] Chr12:21642019 [GRCh38]
Chr12:21794953 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301)x3 copy number gain See cases [RCV000449191] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11		 pathogenic
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865)x3 copy number gain See cases [RCV000449287] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain See cases [RCV000447551] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p12.3-11.23(chr12:18037107-26681362)x3 copy number gain See cases [RCV000446008] Chr12:18037107..26681362 [GRCh37]
Chr12:12p12.3-11.23		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:189578-34756150) copy number gain See cases [RCV000446017] Chr12:189578..34756150 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p12.2-12.1(chr12:20837998-22734873)x3 copy number gain See cases [RCV000448036] Chr12:20837998..22734873 [GRCh37]
Chr12:12p12.2-12.1		 likely pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:565369-34835837)x3 copy number gain See cases [RCV000511580] Chr12:565369..34835837 [GRCh37]
Chr12:12p13.33-11.1		 likely pathogenic
GRCh37/hg19 12p13.33-11.22(chr12:173786-28219229)x3 copy number gain See cases [RCV000510961] Chr12:173786..28219229 [GRCh37]
Chr12:12p13.33-11.22		 pathogenic
NM_002300.8(LDHB):c.910G>A (p.Val304Ile) single nucleotide variant not specified [RCV004306053] Chr12:21635637 [GRCh38]
Chr12:21788571 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.877C>G (p.Pro293Ala) single nucleotide variant not specified [RCV004298359] Chr12:21635670 [GRCh38]
Chr12:21788604 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain not provided [RCV000683479] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x2,3 copy number gain not provided [RCV000683478] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p12.1(chr12:21755837-22023573)x3 copy number gain not provided [RCV000683414] Chr12:21755837..22023573 [GRCh37]
Chr12:12p12.1		 likely benign|uncertain significance
GRCh37/hg19 12p13.33-q11(chr12:173786-37869107)x3 copy number gain not provided [RCV000683480] Chr12:173786..37869107 [GRCh37]
Chr12:12p13.33-q11		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33		 pathogenic
GRCh37/hg19 12p13.33-11.21(chr12:191619-31733044)x3 copy number gain not provided [RCV000750245] Chr12:191619..31733044 [GRCh37]
Chr12:12p13.33-11.21		 pathogenic
NM_002300.8(LDHB):c.726C>T (p.Val242=) single nucleotide variant not provided [RCV000921541] Chr12:21637182 [GRCh38]
Chr12:21790116 [GRCh37]
Chr12:12p12.1		 likely benign
GRCh37/hg19 12p13.33-q11(chr12:274676-37869301)x4 copy number gain not provided [RCV001006470] Chr12:274676..37869301 [GRCh37]
Chr12:12p13.33-q11		 pathogenic
NM_002300.8(LDHB):c.946C>T (p.Gln316Ter) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV000778364] Chr12:21635601 [GRCh38]
Chr12:21788535 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.435G>A (p.Thr145=) single nucleotide variant LDHB-related disorder [RCV003975716]|not provided [RCV000899704] Chr12:21642112 [GRCh38]
Chr12:21795046 [GRCh37]
Chr12:12p12.1		 benign|likely benign
GRCh37/hg19 12p12.3-12.1(chr12:19762818-22659824)x1 copy number loss not provided [RCV000846444] Chr12:19762818..22659824 [GRCh37]
Chr12:12p12.3-12.1		 uncertain significance
GRCh37/hg19 12p12.3-11.23(chr12:16141429-27733325)x1 copy number loss not provided [RCV000849815] Chr12:16141429..27733325 [GRCh37]
Chr12:12p12.3-11.23		 pathogenic
NM_002300.8(LDHB):c.210C>A (p.Ser70Arg) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001112252] Chr12:21646936 [GRCh38]
Chr12:21799870 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.523A>G (p.Met175Val) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001111785]|LDHB-related disorder [RCV003928710] Chr12:21642024 [GRCh38]
Chr12:21794958 [GRCh37]
Chr12:12p12.1		 likely benign|uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:173786-34496628)x3 copy number gain not provided [RCV000847209] Chr12:173786..34496628 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
NM_002300.8(LDHB):c.826A>G (p.Thr276Ala) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001109487] Chr12:21637082 [GRCh38]
Chr12:21790016 [GRCh37]
Chr12:12p12.1		 uncertain significance
NC_000012.11:g.(?_20522219)_(22089608_?)dup duplication not provided [RCV003105374] Chr12:20522219..22089608 [GRCh37]
Chr12:12p12.2-12.1		 uncertain significance
NM_002300.8(LDHB):c.178A>G (p.Lys60Glu) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001112253] Chr12:21646968 [GRCh38]
Chr12:21799902 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.-34A>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001112255] Chr12:21657778 [GRCh38]
Chr12:21810712 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.843G>A (p.Met281Ile) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001115120] Chr12:21635704 [GRCh38]
Chr12:21788638 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.421+13A>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001111786] Chr12:21643922 [GRCh38]
Chr12:21796856 [GRCh37]
Chr12:12p12.1		 benign
NM_002300.8(LDHB):c.-71C>G single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001113602] Chr12:21657815 [GRCh38]
Chr12:21810749 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.782T>C (p.Ile261Thr) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001109488] Chr12:21637126 [GRCh38]
Chr12:21790060 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.767G>A (p.Ser256Asn) single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001109489] Chr12:21637141 [GRCh38]
Chr12:21790075 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.130-8G>A single nucleotide variant Glycogen storage disease due to lactate dehydrogenase H-subunit deficiency [RCV001112254]|not provided [RCV003393846] Chr12:21647024 [GRCh38]
Chr12:21799958 [GRCh37]
Chr12:12p12.1		 likely benign|uncertain significance
GRCh37/hg19 12p12.1(chr12:21582333-24920271)x1 copy number loss not provided [RCV001258515] Chr12:21582333..24920271 [GRCh37]
Chr12:12p12.1		 pathogenic
GRCh37/hg19 12p12.1(chr12:21759357-22017890) copy number gain not specified [RCV002052980] Chr12:21759357..22017890 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865) copy number gain not specified [RCV002052955] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1		 pathogenic
GRCh37/hg19 12p12.3-11.23(chr12:17884992-26704895) copy number gain not specified [RCV002052974] Chr12:17884992..26704895 [GRCh37]
Chr12:12p12.3-11.23		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837) copy number gain not specified [RCV002052957] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301) copy number gain not specified [RCV002052958] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11		 pathogenic
NC_000012.11:g.(?_21590665)_(22089608_?)del deletion Dilated cardiomyopathy 1O [RCV001920617] Chr12:21590665..22089608 [GRCh37]
Chr12:12p12.1		 uncertain significance
NC_000012.11:g.(?_21590665)_(22089608_?)dup duplication Dilated cardiomyopathy 1O [RCV001958184]|not provided [RCV001958183] Chr12:21590665..22089608 [GRCh37]
Chr12:12p12.1		 uncertain significance|no classifications from unflagged records
GRCh37/hg19 12p13.2-12.1(chr12:10853887-24103810)x1 copy number loss not provided [RCV002292878] Chr12:10853887..24103810 [GRCh37]
Chr12:12p13.2-12.1		 pathogenic
NM_002300.8(LDHB):c.152T>C (p.Leu51Pro) single nucleotide variant not specified [RCV004097513] Chr12:21646994 [GRCh38]
Chr12:21799928 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.839G>A (p.Gly280Glu) single nucleotide variant not specified [RCV004102298] Chr12:21635708 [GRCh38]
Chr12:21788642 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.347A>C (p.Asn116Thr) single nucleotide variant not specified [RCV004159812] Chr12:21644009 [GRCh38]
Chr12:21796943 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.262G>C (p.Ala88Pro) single nucleotide variant not specified [RCV004106885] Chr12:21644094 [GRCh38]
Chr12:21797028 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:176047-34179852)x4 copy number gain Pallister-Killian syndrome [RCV003154827] Chr12:176047..34179852 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p12.1(chr12:21764770-22085125)x3 copy number gain not provided [RCV003484865] Chr12:21764770..22085125 [GRCh37]
Chr12:12p12.1		 uncertain significance
Single allele duplication not provided [RCV003448692] Chr12:188053..34856694 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835641)x3 copy number gain not specified [RCV003986979] Chr12:173786..34835641 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
NM_002300.8(LDHB):c.793T>G (p.Leu265Val) single nucleotide variant not specified [RCV004412620] Chr12:21637115 [GRCh38]
Chr12:21790049 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.557G>A (p.Cys186Tyr) single nucleotide variant not specified [RCV004412619] Chr12:21641990 [GRCh38]
Chr12:21794924 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.227C>T (p.Pro76Leu) single nucleotide variant not specified [RCV004412618] Chr12:21646919 [GRCh38]
Chr12:21799853 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.758T>C (p.Ile253Thr) single nucleotide variant not specified [RCV004642269] Chr12:21637150 [GRCh38]
Chr12:21790084 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.307G>A (p.Glu103Lys) single nucleotide variant not specified [RCV004940039] Chr12:21644049 [GRCh38]
Chr12:21796983 [GRCh37]
Chr12:12p12.1		 uncertain significance
NM_002300.8(LDHB):c.416A>G (p.Asn139Ser) single nucleotide variant not specified [RCV004940040] Chr12:21643940 [GRCh38]
Chr12:21796874 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:173787-34835837)x4 copy number gain not provided [RCV004819308] Chr12:173787..34835837 [GRCh37]
Chr12:12p13.33-11.1		 pathogenic
NM_002300.8(LDHB):c.499G>A (p.Asp167Asn) single nucleotide variant not specified [RCV004940038] Chr12:21642048 [GRCh38]
Chr12:21794982 [GRCh37]
Chr12:12p12.1		 uncertain significance
GRCh37/hg19 12p13.2-11.1(chr12:10155706-34051988)x3 copy number gain not provided [RCV004819309] Chr12:10155706..34051988 [GRCh37]
Chr12:12p13.2-11.1		 pathogenic
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR375hsa-miR-375OncomiRDBexternal_infoNANA21922130

Predicted Target Of
Summary Value
Count of predictions:910
Count of miRNA genes:512
Interacting mature miRNAs:545
Transcripts:ENST00000350669, ENST00000396075, ENST00000396076, ENST00000450584, ENST00000470280, ENST00000470985, ENST00000535112, ENST00000539782, ENST00000542765, ENST00000544151
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597440284GWAS1536358_Hpuberty onset measurement QTL GWAS1536358 (human)2e-08puberty onset measurement122165449821654499Human
597221679GWAS1317753_Hbilirubin measurement QTL GWAS1317753 (human)3e-12bilirubin measurementserum total bilirubin level (CMO:0000376)122163812821638129Human
597246222GWAS1342296_Hbilirubin measurement QTL GWAS1342296 (human)3e-16bilirubin measurementserum total bilirubin level (CMO:0000376)122163812821638129Human
596965740GWAS1085259_Hpuberty onset measurement QTL GWAS1085259 (human)2e-08puberty onset measurement122164466021644661Human
596965821GWAS1085340_Hpuberty onset measurement QTL GWAS1085340 (human)2e-08puberty onset measurement122165449821654499Human
597260674GWAS1356748_Hpuberty onset measurement QTL GWAS1356748 (human)2e-08puberty onset measurement122164466021644661Human

Markers in Region
RH15605  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3713113,932,001 - 113,932,170UniSTSGRCh37
GRCh371221,788,348 - 21,788,524UniSTSGRCh37
Build 361221,679,615 - 21,679,791RGDNCBI36
Celera1226,943,337 - 26,943,513RGD
Celera1394,758,633 - 94,758,802UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,561,942 - 21,562,118UniSTS
HuRef1394,370,909 - 94,371,078UniSTS
GDB:384749  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,788,505 - 21,788,733UniSTSGRCh37
Build 361221,679,772 - 21,680,000RGDNCBI36
Celera1226,943,494 - 26,943,722RGD
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,562,099 - 21,562,327UniSTS
SHGC-132102  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,788,315 - 21,788,428UniSTSGRCh37
GRCh37X75,555,081 - 75,555,191UniSTSGRCh37
Build 36X75,471,485 - 75,471,595RGDNCBI36
CeleraX75,834,809 - 75,834,919RGD
Celera1226,943,304 - 26,943,417UniSTS
Cytogenetic MapXq13.3UniSTS
Cytogenetic Map12p12.2-p12.1UniSTS
HuRefX69,186,829 - 69,186,939UniSTS
HuRef1221,561,909 - 21,562,022UniSTS
TNG Radiation Hybrid MapX18479.0UniSTS
G07018  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,788,521 - 21,788,630UniSTSGRCh37
GRCh37X75,555,285 - 75,555,394UniSTSGRCh37
Build 36X75,471,689 - 75,471,798RGDNCBI36
Celera1226,943,510 - 26,943,619UniSTS
CeleraX75,835,013 - 75,835,122RGD
Cytogenetic Map12p12.2-p12.1UniSTS
Cytogenetic MapXq13.3UniSTS
HuRef1221,562,115 - 21,562,224UniSTS
HuRefX69,187,033 - 69,187,142UniSTS
SHGC-173311  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,808,677 - 21,808,975UniSTSGRCh37
Build 361221,699,944 - 21,700,242RGDNCBI36
Celera1226,963,678 - 26,963,976RGD
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,582,294 - 21,582,592UniSTS
STS-X13800  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,787,983 - 21,788,230UniSTSGRCh37
Build 361221,679,250 - 21,679,497RGDNCBI36
Celera1226,942,972 - 26,943,219RGD
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,561,577 - 21,561,824UniSTS
GeneMap99-GB4 RH Map1280.82UniSTS
SHGC-12682  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,788,296 - 21,788,471UniSTSGRCh37
Build 361221,679,563 - 21,679,738RGDNCBI36
Celera1226,943,285 - 26,943,460RGD
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,561,890 - 21,562,065UniSTS
GeneMap99-G3 RH Map121178.0UniSTS
D13S838E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371221,788,507 - 21,790,023UniSTSGRCh37
Celera1226,943,496 - 26,945,012UniSTS
Cytogenetic Map12p12.2-p12.1UniSTS
HuRef1221,562,101 - 21,563,617UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1204 2431 2788 2247 4950 1723 2345 4 621 1948 463 2268 7282 6456 52 3716 848 1730 1613 171

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_017038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001174097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001315537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006719074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC010197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL516910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY189689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC071860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT019764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT019765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU540074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX867875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU794633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU919185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM005565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000350669   ⟹   ENSP00000229319
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,635,342 - 21,657,842 (-)Ensembl
Ensembl Acc Id: ENST00000396075   ⟹   ENSP00000379385
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,638,368 - 21,657,362 (-)Ensembl
Ensembl Acc Id: ENST00000396076   ⟹   ENSP00000379386
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,635,342 - 21,657,794 (-)Ensembl
Ensembl Acc Id: ENST00000450584   ⟹   ENSP00000398015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,643,946 - 21,657,839 (-)Ensembl
Ensembl Acc Id: ENST00000470280
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,643,545 - 21,654,570 (-)Ensembl
Ensembl Acc Id: ENST00000470985
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,635,342 - 21,638,538 (-)Ensembl
Ensembl Acc Id: ENST00000535112
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,654,657 - 21,757,831 (-)Ensembl
Ensembl Acc Id: ENST00000539782   ⟹   ENSP00000442680
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,644,050 - 21,757,857 (-)Ensembl
Ensembl Acc Id: ENST00000542765
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,635,342 - 21,637,374 (-)Ensembl
Ensembl Acc Id: ENST00000544151
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,654,355 - 21,657,971 (-)Ensembl
Ensembl Acc Id: ENST00000673047   ⟹   ENSP00000500484
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1221,635,342 - 21,657,842 (-)Ensembl
RefSeq Acc Id: NM_001174097   ⟹   NP_001167568
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
GRCh371221,788,275 - 21,810,789 (-)ENTREZGENE
HuRef1221,561,869 - 21,584,405 (-)ENTREZGENE
CHM1_11221,753,524 - 21,775,995 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001315537   ⟹   NP_001302466
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
CHM1_11221,753,524 - 21,776,056 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001414233   ⟹   NP_001401162
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
RefSeq Acc Id: NM_001414234   ⟹   NP_001401163
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
RefSeq Acc Id: NM_001414235   ⟹   NP_001401164
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
RefSeq Acc Id: NM_002300   ⟹   NP_002291
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,635,342 - 21,657,842 (-)NCBI
GRCh371221,788,275 - 21,810,789 (-)ENTREZGENE
Build 361221,679,543 - 21,702,043 (-)NCBI Archive
HuRef1221,561,869 - 21,584,405 (-)ENTREZGENE
CHM1_11221,753,524 - 21,776,056 (-)NCBI
T2T-CHM13v2.01221,513,920 - 21,536,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006719074   ⟹   XP_006719137
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,636,831 - 21,657,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054372046   ⟹   XP_054228021
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01221,515,409 - 21,536,444 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001167568 (Get FASTA)   NCBI Sequence Viewer  
  NP_001302466 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401162 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401163 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401164 (Get FASTA)   NCBI Sequence Viewer  
  NP_002291 (Get FASTA)   NCBI Sequence Viewer  
  XP_006719137 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228021 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH02362 (Get FASTA)   NCBI Sequence Viewer  
  AAH15122 (Get FASTA)   NCBI Sequence Viewer  
  AAH71860 (Get FASTA)   NCBI Sequence Viewer  
  AAO85222 (Get FASTA)   NCBI Sequence Viewer  
  AAV38569 (Get FASTA)   NCBI Sequence Viewer  
  AAV38570 (Get FASTA)   NCBI Sequence Viewer  
  ACF98331 (Get FASTA)   NCBI Sequence Viewer  
  ACJ13687 (Get FASTA)   NCBI Sequence Viewer  
  AEE61162 (Get FASTA)   NCBI Sequence Viewer  
  BAA05734 (Get FASTA)   NCBI Sequence Viewer  
  BAD92468 (Get FASTA)   NCBI Sequence Viewer  
  BAG35250 (Get FASTA)   NCBI Sequence Viewer  
  CAA32033 (Get FASTA)   NCBI Sequence Viewer  
  CAA68701 (Get FASTA)   NCBI Sequence Viewer  
  EAW96448 (Get FASTA)   NCBI Sequence Viewer  
  EAW96449 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000229319
  ENSP00000229319.1
  ENSP00000379385
  ENSP00000379385.1
  ENSP00000379386
  ENSP00000379386.1
  ENSP00000398015.1
  ENSP00000442680.1
  ENSP00000497202.1
  ENSP00000500484
  ENSP00000500484.2
GenBank Protein P07195 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_002291   ⟸   NM_002300
- Peptide Label: isoform LDHB
- UniProtKB: P07195 (UniProtKB/Swiss-Prot),   Q5U077 (UniProtKB/TrEMBL),   A0A3B3IS95 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001167568   ⟸   NM_001174097
- Peptide Label: isoform LDHB
- UniProtKB: P07195 (UniProtKB/Swiss-Prot),   Q5U077 (UniProtKB/TrEMBL),   A0A3B3IS95 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006719137   ⟸   XM_006719074
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001302466   ⟸   NM_001315537
- Peptide Label: isoform LDHBx
- UniProtKB: A0A5F9ZHM4 (UniProtKB/TrEMBL),   A0A3B3IS95 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000500484   ⟸   ENST00000673047
Ensembl Acc Id: ENSP00000398015   ⟸   ENST00000450584
Ensembl Acc Id: ENSP00000229319   ⟸   ENST00000350669
Ensembl Acc Id: ENSP00000442680   ⟸   ENST00000539782
Ensembl Acc Id: ENSP00000379386   ⟸   ENST00000396076
Ensembl Acc Id: ENSP00000379385   ⟸   ENST00000396075
RefSeq Acc Id: NP_001401163   ⟸   NM_001414234
- Peptide Label: isoform 4
RefSeq Acc Id: NP_001401162   ⟸   NM_001414233
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001401164   ⟸   NM_001414235
- Peptide Label: isoform 5
- UniProtKB: A8MW50 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054228021   ⟸   XM_054372046
- Peptide Label: isoform X1
Protein Domains
Lactate/malate dehydrogenase C-terminal   Lactate/malate dehydrogenase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P07195-F1-model_v2 AlphaFold P07195 1-334 view protein structure

Promoters
RGD ID:7223413
Promoter ID:EPDNEW_H17452
Type:initiation region
Name:LDHB_1
Description:lactate dehydrogenase B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381221,657,842 - 21,657,902EPDNEW
RGD ID:6790190
Promoter ID:HG_KWN:15189
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Jurkat
Transcripts:OTTHUMT00000258224,   UC001RFC.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361221,698,476 - 21,698,976 (-)MPROMDB
RGD ID:6790189
Promoter ID:HG_KWN:15190
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000396075,   NM_001174097,   NM_002300,   OTTHUMT00000258221,   OTTHUMT00000258223
Position:
Human AssemblyChrPosition (strand)Source
Build 361221,701,711 - 21,702,211 (-)MPROMDB
RGD ID:6851774
Promoter ID:EP73691
Type:initiation region
Name:HS_LDHB
Description:Lactate dehydrogenase B.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361221,702,043 - 21,702,103EPD

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6541 AgrOrtholog
COSMIC LDHB COSMIC
Ensembl Genes ENSG00000111716 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000285854 UniProtKB/TrEMBL
Ensembl Transcript ENST00000350669 ENTREZGENE
  ENST00000350669.5 UniProtKB/Swiss-Prot
  ENST00000396075 ENTREZGENE
  ENST00000396075.5 UniProtKB/TrEMBL
  ENST00000396076 ENTREZGENE
  ENST00000396076.5 UniProtKB/Swiss-Prot
  ENST00000450584.5 UniProtKB/TrEMBL
  ENST00000539782.1 UniProtKB/TrEMBL
  ENST00000647960.1 UniProtKB/TrEMBL
  ENST00000673047 ENTREZGENE
  ENST00000673047.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000111716 GTEx
  ENSG00000285854 GTEx
HGNC ID HGNC:6541 ENTREZGENE
Human Proteome Map LDHB Human Proteome Map
InterPro L-lactate/malate_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  L-lactate_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  L-lactate_DH_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lactate/malate_DH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lactate/malate_DH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lactate_DH/Glyco_Ohase_4_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 3945 ENTREZGENE
OMIM 150100 OMIM
PANTHER L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  L-LACTATE DEHYDROGENASE B CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ldh_1_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ldh_1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30325 PharmGKB
PIRSF Lac_mal_DH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS LLDHDRGNASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE L_LDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56327 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A3B3IS95 ENTREZGENE, UniProtKB/TrEMBL
  A0A5F9ZHM4 ENTREZGENE, UniProtKB/TrEMBL
  A8MW50 ENTREZGENE, UniProtKB/TrEMBL
  C9J7H8_HUMAN UniProtKB/TrEMBL
  F5H793_HUMAN UniProtKB/TrEMBL
  LDHB_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U077 ENTREZGENE, UniProtKB/TrEMBL