(-)-demecolcine increases expression ISO RGD:735430 6480464 Demecolcine results in increased expression of IL1R1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:735430 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1R1 mRNA CTD PMID:22079256 (2,4,5-trichlorophenoxy)acetic acid decreases expression EXP 6480464 2 more ... CTD PMID:18579281 (S)-nicotine multiple interactions ISO RGD:2892 6480464 methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 mRNA], methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 protein] CTD PMID:27180639 (S)-nicotine increases expression ISO RGD:2892 6480464 Nicotine results in increased expression of IL1R1 mRNA, Nicotine results in increased expression of IL1R1 protein CTD PMID:27180639 1,10-phenanthroline decreases expression ISO RGD:735430 6480464 1, 10-phenanthroline results in decreased expression of IL1R1 mRNA CTD PMID:19502547 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of IL1R1 mRNA CTD PMID:28960355 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IL1R1 mRNA CTD PMID:22206623 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of IL1R1 mRNA CTD PMID:15913567 1-naphthyl isothiocyanate increases expression ISO RGD:2892 6480464 1-Naphthylisothiocyanate results in increased expression of IL1R1 mRNA CTD PMID:12832660 17beta-estradiol multiple interactions ISO RGD:735430 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of IL1R1 mRNA more ... CTD PMID:19619570 more ... 17beta-estradiol decreases expression ISO RGD:735430 6480464 Estradiol results in decreased expression of IL1R1 mRNA CTD PMID:16202921 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IL1R1 mRNA CTD PMID:15171707 17beta-estradiol increases expression ISO RGD:735430 6480464 Estradiol results in increased expression of IL1R1 mRNA CTD PMID:19619570 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:735430 6480464 Dihydrotestosterone results in increased expression of IL1R1 mRNA CTD PMID:29581250 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:735430 6480464 2 more ... CTD PMID:23146750 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735430 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of IL1R1 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2892 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL1R1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2892 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1R1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of IL1R1 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1R1 mRNA CTD PMID:15667827 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases response to substance EXP 6480464 IL1R1 gene mutant form results in decreased susceptibility to Tetrachlorodibenzodioxin CTD PMID:24718703 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735430 6480464 Tetrachlorodibenzodioxin results in increased expression of IL1R1 mRNA CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:2892 6480464 Tetrachlorodibenzodioxin affects the expression of IL1R1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL1R1 mRNA CTD PMID:19465110 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:2892 6480464 Active Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA], Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] CTD PMID:17449585 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:2892 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA CTD PMID:17449585 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:2892 6480464 3 more ... CTD PMID:20959002 more ... 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:735430 6480464 3 more ... CTD PMID:35618242 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of IL1R1 mRNA CTD PMID:20188158 , PMID:26251327 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735430 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of IL1R1 mRNA CTD PMID:28628672 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of IL1R1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of IL1R1 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO RGD:735430 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of IL1R1 gene CTD PMID:31601247 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid decreases expression ISO RGD:735430 6480464 Am 580 results in decreased expression of IL1R1 mRNA CTD PMID:16982809 4-hydroxycyclophosphamide multiple interactions ISO RGD:2892 6480464 [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL1R1 mRNA CTD PMID:25833159 6-propyl-2-thiouracil increases expression ISO RGD:2892 6480464 Propylthiouracil results in increased expression of IL1R1 mRNA CTD PMID:22504374 acetamide decreases expression ISO RGD:2892 6480464 acetamide results in decreased expression of IL1R1 mRNA CTD PMID:31881176 acrylamide decreases expression ISO RGD:2892 6480464 Acrylamide results in decreased expression of IL1R1 mRNA CTD PMID:28959563 adenosine multiple interactions ISO RGD:2892 6480464 Adenosine inhibits the reaction [IL1B protein results in increased expression of IL1R1] CTD PMID:24878381 afimoxifene multiple interactions ISO RGD:2892 6480464 [afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of IL1R1 mRNA CTD PMID:25833159 aflatoxin B1 decreases methylation ISO RGD:735430 6480464 Aflatoxin B1 results in decreased methylation of IL1R1 gene CTD PMID:27153756 AH23848 multiple interactions ISO RGD:735430 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [[ARRB1 protein modified form binds to SRC protein] which binds to IL1R1 protein], [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased expression of IL1R1 protein CTD PMID:19407222 albendazole multiple interactions ISO RGD:735430 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 aldrin decreases expression EXP 6480464 Aldrin results in decreased expression of IL1R1 mRNA CTD PMID:18579281 all-trans-retinoic acid increases expression ISO RGD:735430 6480464 Tretinoin results in increased expression of IL1R1 mRNA CTD PMID:21934132 aluminium hydroxide multiple interactions EXP 6480464 IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 ammonium chloride affects expression ISO RGD:2892 6480464 Ammonium Chloride affects the expression of IL1R1 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:735430 6480464 Antirheumatic Agents results in decreased expression of IL1R1 mRNA CTD PMID:24449571 arotinoid acid multiple interactions ISO RGD:735430 6480464 [4-(2-(5 more ... CTD PMID:34480604 arsane increases expression ISO RGD:735430 6480464 Arsenic results in increased expression of IL1R1 mRNA CTD PMID:19945496 arsane multiple interactions ISO RGD:2892 6480464 4 more ... CTD PMID:35993674 arsane affects methylation ISO RGD:735430 6480464 Arsenic affects the methylation of IL1R1 gene CTD PMID:25304211 arsenic atom increases expression ISO RGD:735430 6480464 Arsenic results in increased expression of IL1R1 mRNA CTD PMID:19945496 arsenic atom multiple interactions ISO RGD:2892 6480464 4 more ... CTD PMID:35993674 arsenic atom affects methylation ISO RGD:735430 6480464 Arsenic affects the methylation of IL1R1 gene CTD PMID:25304211 asperentin increases expression EXP 6480464 cladosporin results in increased expression of IL1R1 mRNA CTD PMID:19818335 atrazine multiple interactions ISO RGD:735430 6480464 [Atrazine co-treated with Arsenates] results in increased expression of IL1R1 mRNA CTD PMID:18585445 Bardoxolone methyl affects expression ISO RGD:735430 6480464 bardoxolone methyl affects the expression of IL1R1 mRNA CTD PMID:34480604 benzene decreases expression ISO RGD:735430 6480464 Benzene results in decreased expression of IL1R1 mRNA CTD PMID:33064461 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of IL1R1 mRNA CTD PMID:27195522 benzo[a]pyrene affects methylation ISO RGD:735430 6480464 Benzo(a)pyrene affects the methylation of IL1R1 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of IL1R1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:735430 6480464 Benzo(a)pyrene results in decreased expression of IL1R1 mRNA CTD PMID:22316170 beta-naphthoflavone multiple interactions ISO RGD:2892 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL1R1 mRNA CTD PMID:18164116 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735430 6480464 Diethylhexyl Phthalate results in increased expression of IL1R1 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:2892 6480464 bisphenol A results in decreased expression of IL1R1 mRNA CTD PMID:25181051 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IL1R1 mRNA CTD PMID:30951980 , PMID:35598803 bisphenol A increases expression ISO RGD:735430 6480464 bisphenol A results in increased expression of IL1R1 mRNA CTD PMID:29275510 bisphenol A increases methylation ISO RGD:2892 6480464 bisphenol A results in increased methylation of IL1R1 gene CTD PMID:28505145 bisphenol F multiple interactions ISO RGD:735430 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of IL1R1 mRNA CTD PMID:28628672 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of IL1R1 mRNA CTD PMID:30951980 bortezomib increases expression ISO RGD:735430 6480464 Bortezomib results in increased expression of IL1R1 mRNA CTD PMID:17895889 butanal decreases expression ISO RGD:735430 6480464 butyraldehyde results in decreased expression of IL1R1 mRNA CTD PMID:26079696 cadmium dichloride multiple interactions ISO RGD:2892 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of IL1R1 protein CTD PMID:26396915 calcitriol increases expression ISO RGD:735430 6480464 Calcitriol results in increased expression of IL1R1 mRNA CTD PMID:16002434 cannabidiol multiple interactions ISO RGD:735430 6480464 Cannabidiol inhibits the reaction [TNF protein results in decreased expression of IL1R1 mRNA] CTD PMID:31250491 cannabidiol decreases expression ISO RGD:735430 6480464 Cannabidiol results in decreased expression of IL1R1 mRNA CTD PMID:27932991 , PMID:31801206 captan decreases expression EXP 6480464 Captan results in decreased expression of IL1R1 mRNA CTD PMID:31558096 carbamazepine affects expression ISO RGD:735430 6480464 Carbamazepine affects the expression of IL1R1 mRNA CTD PMID:24752500 carbon nanotube increases expression ISO RGD:735430 6480464 Nanotubes, Carbon results in increased expression of IL1R1 mRNA CTD PMID:25511174 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carbon nanotube affects expression EXP 6480464 Nanotubes, Carbon affects the expression of IL1R1 mRNA CTD PMID:23845593 , PMID:25620056 carmustine affects response to substance ISO RGD:735430 6480464 IL1R1 mRNA affects the susceptibility to Carmustine CTD PMID:16365179 carrageenan multiple interactions EXP 6480464 IL1R1 protein promotes the reaction [Carrageenan results in increased expression of ICAM1 protein] more ... CTD PMID:15380531 carrageenan increases response to substance EXP 6480464 IL1R1 protein results in increased susceptibility to Carrageenan CTD PMID:15380531 chenodeoxycholic acid multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA more ... CTD PMID:33819548 CHIR 99021 multiple interactions ISO RGD:735430 6480464 [4-(2-(5 more ... CTD PMID:34480604 chloroethene decreases expression EXP 6480464 Vinyl Chloride results in decreased expression of IL1R1 mRNA CTD PMID:18579281 chromium(6+) decreases expression ISO RGD:735430 6480464 chromium hexavalent ion results in decreased expression of IL1R1 mRNA CTD PMID:30690063 chrysin decreases expression ISO RGD:735430 6480464 chrysin results in decreased expression of IL1R1 mRNA CTD PMID:20816778 ciglitazone multiple interactions ISO RGD:735430 6480464 [ciglitazone binds to PPARG protein] which results in increased expression of IL1R1 mRNA CTD PMID:16197558 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of IL1R1 mRNA CTD PMID:18353800 cisplatin affects response to substance ISO RGD:735430 6480464 IL1R1 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cisplatin decreases expression ISO RGD:735430 6480464 Cisplatin results in decreased expression of IL1R1 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO RGD:735430 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of IL1R1 mRNA CTD PMID:27392435 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IL1R1 mRNA CTD PMID:26546572 copper atom multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of IL1R1 mRNA CTD PMID:15467011 copper atom multiple interactions ISO RGD:735430 6480464 [Chelating Agents binds to Copper] which results in decreased expression of IL1R1 mRNA CTD PMID:30911355 copper(0) multiple interactions EXP 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of IL1R1 mRNA CTD PMID:15467011 copper(0) multiple interactions ISO RGD:735430 6480464 [Chelating Agents binds to Copper] which results in decreased expression of IL1R1 mRNA CTD PMID:30911355 copper(II) sulfate decreases expression ISO RGD:735430 6480464 Copper Sulfate results in decreased expression of IL1R1 mRNA CTD PMID:19549813 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of IL1R1 mRNA CTD PMID:18579281 cortisol multiple interactions ISO RGD:735430 6480464 [4-(2-(5 more ... CTD PMID:34480604 coumestrol multiple interactions ISO RGD:735430 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IL1R1 mRNA CTD PMID:19167446 cyclophosphamide multiple interactions ISO RGD:2892 6480464 naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1R1 mRNA] CTD PMID:33992719 cyclophosphamide increases expression ISO RGD:2892 6480464 Cyclophosphamide results in increased expression of IL1R1 mRNA CTD PMID:33992719 cyclosporin A decreases expression ISO RGD:735430 6480464 Cyclosporine results in decreased expression of IL1R1 mRNA CTD PMID:25562108 , PMID:27989131 DDT increases expression ISO RGD:2892 6480464 DDT results in increased expression of IL1R1 mRNA CTD PMID:11948501 DDT decreases expression ISO RGD:2892 6480464 DDT results in decreased expression of IL1R1 mRNA CTD PMID:11948501 deoxycholic acid multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA more ... CTD PMID:33819548 deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of IL1R1 mRNA CTD PMID:22968694 deoxynivalenol multiple interactions EXP 6480464 IL1R1 protein affects the susceptibility to [Lipopolysaccharides co-treated with deoxynivalenol] CTD PMID:12773775 dexamethasone multiple interactions ISO RGD:735430 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of IL1R1 mRNA CTD PMID:28628672 dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL1R1 mRNA, Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL1R1 mRNA] CTD PMID:29950665 , PMID:32033881 dextran sulfate increases expression EXP 6480464 Dextran Sulfate results in increased expression of IL1R1 mRNA CTD PMID:32033881 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IL1R1 mRNA CTD PMID:17361019 , PMID:21266533 dichloroacetic acid decreases expression EXP 6480464 Dichloroacetic Acid results in decreased expression of IL1R1 mRNA CTD PMID:28962523 diclofenac affects expression ISO RGD:735430 6480464 Diclofenac affects the expression of IL1R1 mRNA CTD PMID:24752500 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of IL1R1 mRNA CTD PMID:26934552 diethyl maleate affects expression ISO RGD:735430 6480464 diethyl maleate affects the expression of IL1R1 mRNA CTD PMID:34480604 dimethyl sulfoxide decreases expression ISO RGD:735430 6480464 Dimethyl Sulfoxide results in decreased expression of IL1R1 mRNA CTD PMID:21878375 dorsomorphin multiple interactions ISO RGD:735430 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:2892 6480464 Fungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of IL1R1 mRNA] CTD PMID:27181935 doxorubicin decreases expression ISO RGD:735430 6480464 Doxorubicin results in decreased expression of IL1R1 mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:2892 6480464 Doxorubicin results in increased expression of IL1R1 mRNA CTD PMID:27181935 edaravone multiple interactions ISO RGD:2892 6480464 Edaravone inhibits the reaction [[IL1B protein results in increased phosphorylation of AKT1 protein] which results in increased expression of IL1R1 mRNA], Edaravone inhibits the reaction [[IL1B protein results in increased phosphorylation of AKT1 protein] which results in increased expression of IL1R1 protein] CTD PMID:18078833 ellagic acid decreases expression ISO RGD:735430 6480464 Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 endosulfan decreases expression ISO RGD:2892 6480464 Endosulfan results in decreased expression of IL1R1 mRNA CTD PMID:29391264 Enterolactone multiple interactions ISO RGD:735430 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IL1R1 mRNA CTD PMID:19167446 erlotinib hydrochloride multiple interactions ISO RGD:735430 6480464 [Erlotinib Hydrochloride results in decreased susceptibility to Erlotinib Hydrochloride] which results in decreased expression of IL1R1 mRNA CTD PMID:27738319 fenvalerate increases expression ISO RGD:2892 6480464 fenvalerate results in increased expression of IL1R1 mRNA CTD PMID:30307764 flavonoids increases expression ISO RGD:2892 6480464 Flavonoids results in increased expression of IL1R1 mRNA CTD PMID:18035473 folic acid multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IL1R1 mRNA CTD PMID:22206623 folpet decreases expression EXP 6480464 folpet results in decreased expression of IL1R1 mRNA CTD PMID:31558096 fonofos decreases methylation ISO RGD:735430 6480464 Fonofos results in decreased methylation of IL1R1 promoter CTD PMID:22847954 formaldehyde decreases expression ISO RGD:735430 6480464 Formaldehyde results in decreased expression of IL1R1 mRNA CTD PMID:20655997 formaldehyde increases expression ISO RGD:735430 6480464 Formaldehyde results in increased expression of IL1R1 mRNA CTD PMID:23649840 fulvestrant increases methylation ISO RGD:735430 6480464 Fulvestrant results in increased methylation of IL1R1 gene CTD PMID:31601247 furan decreases expression ISO RGD:2892 6480464 furan results in decreased expression of IL1R1 mRNA CTD PMID:25539665 gallic acid decreases expression ISO RGD:735430 6480464 Gallic Acid results in decreased expression of IL1R1 mRNA CTD PMID:34408198 genistein multiple interactions ISO RGD:2892 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IL1R1 mRNA CTD PMID:21782745 gentamycin decreases expression ISO RGD:2892 6480464 Gentamicins results in decreased expression of IL1R1 mRNA CTD PMID:33387578 glycochenodeoxycholic acid multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA more ... CTD PMID:33819548 glycocholic acid multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA more ... CTD PMID:33819548 glycodeoxycholic acid multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA more ... CTD PMID:33819548 hydrogen peroxide multiple interactions ISO RGD:735430 6480464 Hydrogen Peroxide promotes the reaction [TRAF6 protein binds to [IL1R1 protein binds to MYD88 protein]] CTD PMID:16354686 indirubin decreases expression ISO RGD:735430 6480464 indirubin results in decreased expression of IL1R1 mRNA CTD PMID:15056799 indometacin multiple interactions ISO RGD:735430 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of IL1R1 mRNA CTD PMID:28628672 ivermectin multiple interactions ISO RGD:735430 6480464 [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 L-ascorbic acid multiple interactions ISO RGD:735430 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA CTD PMID:34480604 L-ascorbic acid 2-phosphate multiple interactions ISO RGD:735430 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA CTD PMID:34480604 lead diacetate multiple interactions ISO RGD:2892 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of IL1R1 protein CTD PMID:26396915 leflunomide increases expression ISO RGD:2892 6480464 leflunomide results in increased expression of IL1R1 mRNA CTD PMID:24136188 lenalidomide decreases expression ISO RGD:735430 6480464 lenalidomide results in decreased expression of IL1R1 mRNA CTD PMID:15618473 Licochalcone B decreases expression ISO RGD:735430 6480464 licochalcone B results in decreased expression of IL1R1 mRNA CTD PMID:33647349 lipopolysaccharide multiple interactions ISO RGD:735430 6480464 [S-(1 more ... CTD PMID:21135123 , PMID:35811015 lipopolysaccharide increases expression ISO RGD:2892 6480464 Lipopolysaccharides results in increased expression of IL1R1 mRNA CTD PMID:13679239 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IL1R1 mRNA CTD PMID:15371095 , PMID:25843059 lipopolysaccharide multiple interactions EXP 6480464 3 more ... CTD PMID:12773775 more ... lipopolysaccharide increases expression ISO RGD:735430 6480464 Lipopolysaccharides results in increased expression of IL1R1 mRNA CTD PMID:21045076 more ... magnesium dihydroxide multiple interactions EXP 6480464 IL1R1 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein] CTD PMID:18604214 manganese(II) chloride increases expression ISO RGD:2892 6480464 manganese chloride results in increased expression of IL1R1 mRNA CTD PMID:28801915 methimazole increases expression ISO RGD:2892 6480464 Methimazole results in increased expression of IL1R1 mRNA CTD PMID:22504374 methoxychlor multiple interactions ISO RGD:2892 6480464 [Genistein co-treated with Methoxychlor] results in increased expression of IL1R1 mRNA CTD PMID:21782745 methoxychlor increases expression ISO RGD:2892 6480464 Methoxychlor results in increased expression of IL1R1 mRNA CTD PMID:21782745 methyllycaconitine multiple interactions ISO RGD:2892 6480464 methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 mRNA], methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 protein] CTD PMID:27180639 Muraglitazar decreases expression ISO RGD:2892 6480464 muraglitazar results in decreased expression of IL1R1 mRNA CTD PMID:21515302 mycophenolic acid increases expression EXP 6480464 Mycophenolic Acid results in increased expression of IL1R1 mRNA CTD PMID:19818335 mycotoxin increases expression EXP 6480464 Mycotoxins results in increased expression of IL1R1 mRNA CTD PMID:19818335 N-methyl-4-phenylpyridinium increases expression ISO RGD:2892 6480464 1-Methyl-4-phenylpyridinium results in increased expression of IL1R1 mRNA CTD PMID:28801915 N-nitrosodiethylamine multiple interactions ISO RGD:2892 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL1R1 mRNA CTD PMID:18164116 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of IL1R1 mRNA CTD PMID:17869372 N-nitrosodimethylamine multiple interactions EXP 6480464 CSF3 protein affects the reaction [Dimethylnitrosamine results in increased expression of IL1R1 mRNA] CTD PMID:17869372 naringin multiple interactions ISO RGD:2892 6480464 naringin inhibits the reaction [Cyclophosphamide results in increased expression of IL1R1 mRNA] CTD PMID:33992719 neoechinulin A increases expression EXP 6480464 neoechinulin A results in increased expression of IL1R1 mRNA CTD PMID:19818335 nickel sulfate increases expression ISO RGD:735430 6480464 nickel sulfate results in increased expression of IL1R1 mRNA CTD PMID:22714537 nicotine multiple interactions ISO RGD:2892 6480464 methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 mRNA], methyllycaconitine affects the reaction [Nicotine results in increased expression of IL1R1 protein] CTD PMID:27180639 nicotine increases expression ISO RGD:2892 6480464 Nicotine results in increased expression of IL1R1 mRNA, Nicotine results in increased expression of IL1R1 protein CTD PMID:27180639 Nor-9-carboxy-delta9-THC multiple interactions ISO RGD:735430 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of IL1R1 gene CTD PMID:30521419 o-anisidine increases expression ISO RGD:735430 6480464 2-anisidine results in increased expression of IL1R1 mRNA CTD PMID:28089782 ozone multiple interactions EXP 6480464 IL1R1 gene mutant form affects the reaction [Ozone results in increased expression of CCL11 protein] more ... CTD PMID:17575079 ozone increases expression EXP 6480464 Ozone results in increased expression of IL1R1 mRNA CTD PMID:26342085 , PMID:30848106 ozone increases response to substance EXP 6480464 IL1R1 protein results in increased susceptibility to Ozone CTD PMID:17575079 paclitaxel decreases expression ISO RGD:735430 6480464 Paclitaxel results in decreased expression of IL1R1 protein CTD PMID:15907983 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of IL1R1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:2892 6480464 Acetaminophen results in decreased expression of IL1R1 mRNA CTD PMID:33387578 paracetamol multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in increased expression of IL1R1 mRNA CTD PMID:33819548 paracetamol multiple interactions EXP 6480464 PANX1 gene mutant form promotes the reaction [Acetaminophen results in increased expression of IL1R1 mRNA] CTD PMID:29246445 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IL1R1 mRNA CTD PMID:29246445 paracetamol increases expression ISO RGD:735430 6480464 Acetaminophen results in increased expression of IL1R1 mRNA CTD PMID:26690555 paracetamol decreases expression ISO RGD:735430 6480464 Acetaminophen results in decreased expression of IL1R1 mRNA CTD PMID:21420995 paracetamol affects metabolic processing EXP 6480464 IL1R1 protein affects the metabolism of Acetaminophen CTD PMID:19002106 paracetamol increases response to substance EXP 6480464 IL1R1 protein results in increased susceptibility to Acetaminophen CTD PMID:19002106 parathion decreases methylation ISO RGD:735430 6480464 Parathion results in decreased methylation of IL1R1 promoter CTD PMID:22847954 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:735430 6480464 perfluorooctane sulfonic acid results in decreased expression of IL1R1 mRNA CTD PMID:32219433 , PMID:32790152 perfluorooctanoic acid multiple interactions ISO RGD:735430 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in increased expression of IL1R1 mRNA CTD PMID:33325755 perfluorooctanoic acid decreases expression ISO RGD:735430 6480464 perfluorooctanoic acid results in decreased expression of IL1R1 mRNA CTD PMID:32790152 phenformin increases expression ISO RGD:2892 6480464 Phenformin results in increased expression of IL1R1 mRNA CTD PMID:31324951 phenobarbital affects expression ISO RGD:735430 6480464 Phenobarbital affects the expression of IL1R1 mRNA CTD PMID:19159669 phenylmercury acetate increases expression ISO RGD:735430 6480464 Phenylmercuric Acetate results in increased expression of IL1R1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:735430 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IL1R1 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:735430 6480464 SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA] CTD PMID:21045076 phorbol 13-acetate 12-myristate increases expression ISO RGD:735430 6480464 Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA CTD PMID:21045076 phytoestrogen multiple interactions ISO RGD:735430 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in increased expression of IL1R1 mRNA CTD PMID:33325755 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of IL1R1 mRNA CTD PMID:18301758 , PMID:18445702 potassium chromate multiple interactions ISO RGD:735430 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IL1R1 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:735430 6480464 potassium chromate(VI) results in decreased expression of IL1R1 mRNA CTD PMID:22079256 , PMID:22714537 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of IL1R1 mRNA CTD PMID:28903501 progesterone increases expression ISO RGD:735430 6480464 Progesterone results in increased expression of IL1R1 mRNA CTD PMID:20864642 , PMID:21795739 progesterone increases expression ISO RGD:2892 6480464 Progesterone results in increased expression of IL1R1 mRNA CTD PMID:20726854 prostaglandin E2 increases activity ISO RGD:735430 6480464 Dinoprostone results in increased activity of IL1R1 protein CTD PMID:19407222 prostaglandin E2 increases expression ISO RGD:735430 6480464 Dinoprostone results in increased expression of IL1R1 mRNA CTD PMID:19273625 quercetin increases expression ISO RGD:735430 6480464 Quercetin results in increased expression of IL1R1 mRNA CTD PMID:23727915 quercetin decreases expression ISO RGD:735430 6480464 Quercetin results in decreased expression of IL1R1 mRNA CTD PMID:15309432 , PMID:21632981 raloxifene multiple interactions ISO RGD:735430 6480464 Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of IL1R1 mRNA] CTD PMID:21185374 rotenone increases expression ISO RGD:2892 6480464 Rotenone results in increased expression of IL1R1 mRNA CTD PMID:28374803 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:735430 6480464 [S-(1, 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of IL1R1 mRNA CTD PMID:35811015 SB 431542 multiple interactions ISO RGD:735430 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:34480604 silicon dioxide decreases expression ISO RGD:735430 6480464 Silicon Dioxide analog results in decreased expression of IL1R1 mRNA CTD PMID:25895662 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of IL1R1 mRNA CTD PMID:23221170 silicon dioxide affects response to substance EXP 6480464 IL1R1 protein affects the susceptibility to Silicon Dioxide CTD PMID:18604214 silver atom decreases expression ISO RGD:735430 6480464 Silver analog results in decreased expression of IL1R1 mRNA, Silver results in decreased expression of IL1R1 mRNA CTD PMID:22342292 , PMID:24462830 silver atom increases expression ISO RGD:735430 6480464 Silver analog results in increased expression of IL1R1 mRNA CTD PMID:23086748 silver atom increases expression ISO RGD:2892 6480464 Silver analog results in increased expression of IL1R1 mRNA CTD PMID:23086748 silver(0) decreases expression ISO RGD:735430 6480464 Silver analog results in decreased expression of IL1R1 mRNA, Silver results in decreased expression of IL1R1 mRNA CTD PMID:22342292 , PMID:24462830 silver(0) increases expression ISO RGD:735430 6480464 Silver analog results in increased expression of IL1R1 mRNA CTD PMID:23086748 silver(0) increases expression ISO RGD:2892 6480464 Silver analog results in increased expression of IL1R1 mRNA CTD PMID:23086748 sodium arsenite multiple interactions ISO RGD:735430 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [sodium arsenite results in increased expression of IL1R1 mRNA], LCN2 mutant form inhibits the reaction [sodium arsenite results in increased expression of IL1R1 mRNA] CTD PMID:24570342 sodium arsenite affects expression ISO RGD:735430 6480464 sodium arsenite affects the expression of IL1R1 mRNA CTD PMID:34032870 sodium arsenite decreases methylation EXP 6480464 sodium arsenite results in decreased methylation of IL1R1 gene CTD PMID:24118411 sodium arsenite multiple interactions ISO RGD:2892 6480464 4 more ... CTD PMID:26396915 , PMID:35993674 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of IL1R1 mRNA CTD PMID:21911445 sodium arsenite increases expression ISO RGD:735430 6480464 sodium arsenite results in increased expression of IL1R1 mRNA CTD PMID:22714537 more ... sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of IL1R1 mRNA CTD PMID:31558096 Soman affects response to substance EXP 6480464 IL1R1 protein affects the susceptibility to Soman CTD PMID:28866071 sterigmatocystin increases expression EXP 6480464 Sterigmatocystin results in increased expression of IL1R1 mRNA CTD PMID:19818335 sulfasalazine multiple interactions ISO RGD:2892 6480464 Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1R1 mRNA] CTD PMID:17449585 sulforaphane increases expression ISO RGD:735430 6480464 sulforaphane results in increased expression of IL1R1 mRNA CTD PMID:26833863 sulforaphane decreases expression ISO RGD:735430 6480464 sulforaphane results in decreased expression of IL1R1 mRNA CTD PMID:31838189 sulindac sulfide increases expression ISO RGD:735430 6480464 sulindac sulfide results in increased expression of IL1R1 mRNA CTD PMID:16184548 Sunset Yellow FCF multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of IL1R1 mRNA CTD PMID:33819548 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of IL1R1 mRNA CTD PMID:20937368 tartrazine multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of IL1R1 mRNA CTD PMID:33819548 temozolomide affects response to substance ISO RGD:735430 6480464 IL1R1 mRNA affects the susceptibility to temozolomide CTD PMID:16365179 terbufos decreases methylation ISO RGD:735430 6480464 terbufos results in decreased methylation of IL1R1 promoter CTD PMID:22847954 Tesaglitazar decreases expression ISO RGD:2892 6480464 tesaglitazar results in decreased expression of IL1R1 mRNA CTD PMID:21515302 testosterone increases expression EXP 6480464 Testosterone results in increased expression of IL1R1 mRNA CTD PMID:19693291 testosterone decreases expression ISO RGD:735430 6480464 Testosterone results in decreased expression of IL1R1 mRNA CTD PMID:33359661 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of IL1R1 mRNA CTD PMID:17484886 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of IL1R1 mRNA CTD PMID:31919559 tetrachloromethane multiple interactions ISO RGD:2892 6480464 [almond oil co-treated with Carbon Tetrachloride] results in decreased expression of IL1R1 mRNA CTD PMID:27623180 thalidomide decreases expression ISO RGD:735430 6480464 Thalidomide results in decreased expression of IL1R1 mRNA CTD PMID:15618473 thioacetamide decreases expression ISO RGD:2892 6480464 Thioacetamide results in decreased expression of IL1R1 mRNA CTD PMID:23411599 titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL1R1 mRNA CTD PMID:29950665 toluene decreases expression ISO RGD:735430 6480464 Toluene results in decreased expression of IL1R1 mRNA CTD PMID:33064461 triadimefon increases expression ISO RGD:2892 6480464 triadimefon results in increased expression of IL1R1 mRNA CTD PMID:16643972 tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of IL1R1 mRNA CTD PMID:31939706 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of IL1R1 mRNA CTD PMID:15363585 trichostatin A increases expression ISO RGD:735430 6480464 trichostatin A results in increased expression of IL1R1 mRNA CTD PMID:24935251 triclosan increases expression ISO RGD:735430 6480464 Triclosan results in increased expression of IL1R1 mRNA CTD PMID:30510588 triclosan multiple interactions ISO RGD:735430 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Triclosan] results in increased expression of IL1R1 mRNA CTD PMID:33819548 trimethyltin increases expression EXP 6480464 trimethyltin results in increased expression of IL1R1 mRNA CTD PMID:20833246 triphenyl phosphate increases expression ISO RGD:2892 6480464 triphenyl phosphate results in increased expression of IL1R1 mRNA CTD PMID:30589522 valproic acid affects expression ISO RGD:735430 6480464 Valproic Acid affects the expression of IL1R1 mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:735430 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IL1R1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:735430 6480464 Valproic Acid results in increased expression of IL1R1 mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:735430 6480464 Valproic Acid results in decreased expression of IL1R1 mRNA CTD PMID:29154799 vanadyl sulfate increases expression EXP 6480464 vanadyl sulfate results in increased expression of IL1R1 mRNA CTD PMID:16217019 vinclozolin decreases expression ISO RGD:2892 6480464 vinclozolin results in decreased expression of IL1R1 mRNA CTD PMID:23034163 vinclozolin decreases methylation ISO RGD:2892 6480464 vinclozolin results in decreased methylation of IL1R1 gene CTD PMID:31079544 vincristine increases expression ISO RGD:735430 6480464 Vincristine results in increased expression of IL1R1 mRNA CTD PMID:23649840 XAV939 multiple interactions ISO RGD:735430 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA, [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA CTD PMID:34480604 zinc atom increases expression ISO RGD:2892 6480464 Zinc deficiency results in increased expression of IL1R1 mRNA CTD PMID:9649590 zinc(0) increases expression ISO RGD:2892 6480464 Zinc deficiency results in increased expression of IL1R1 mRNA CTD PMID:9649590 zoledronic acid increases expression ISO RGD:735430 6480464 zoledronic acid results in increased expression of IL1R1 mRNA CTD PMID:24714768