Amelx (amelogenin, X-linked) - Rat Genome Database

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Gene: Amelx (amelogenin, X-linked) Mus musculus
Analyze
Symbol: Amelx
Name: amelogenin, X-linked
RGD ID: 735380
MGI Page MGI
Description: Enables several functions, including growth factor activity; hydroxyapatite binding activity; and metal ion binding activity. Involved in cell adhesion; enamel mineralization; and regulation of cell population proliferation. Located in basement membrane; cell surface; and supramolecular complex. Part of protein-containing complex. Is expressed in several structures, including connective tissue; eye; jaw; nervous system; and skeleton. Used to study amelogenesis imperfecta type 1E. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELY (amelogenin Y-linked).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ALGN; Am; Amel; amelogenin X chromosome; amelogenin, X isoform; Amg; AMGL; AMGX; enamel matrix protein; leucine-rich amelogenin peptide; LRAP; M100888; Rgsc8; Rgsc888
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X167,959,110 - 167,970,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX167,959,110 - 167,970,196 (-)EnsemblGRCm39 Ensembl
GRCm38X169,176,114 - 169,187,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX169,176,114 - 169,187,200 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X165,614,046 - 165,625,141 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X164,524,127 - 164,531,314 (-)NCBIMGSCv36mm8
CeleraX152,339,918 - 152,351,218 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal ameloblast morphology  (IAGP)
abnormal enamel mineralization  (IAGP)
abnormal enamel morphology  (IAGP)
abnormal enamel rod pattern  (IAGP)
abnormal heart morphology  (IEA)
abnormal incisor color  (IAGP)
abnormal incisor morphology  (IAGP)
abnormal lymph node morphology  (IEA)
abnormal mandible morphology  (IAGP)
abnormal molar crown morphology  (IAGP)
abnormal molar cusp morphology  (IAGP)
abnormal molar morphology  (IAGP)
abnormal seminal vesicle morphology  (IEA)
abnormal skin morphology  (IEA)
abnormal spleen morphology  (IEA)
abnormal stomach morphology  (IEA)
abnormal testis morphology  (IEA)
abnormal thymus morphology  (IEA)
abnormal tooth color  (IEA)
abnormal tooth development  (IAGP)
abnormal tooth morphology  (IAGP)
abnormal tooth wear  (IAGP)
abnormal vertebral arch morphology  (IEA)
abnormal zygomatic bone morphology  (IEA)
absent teeth  (IEA)
brittle teeth  (IAGP)
decreased body weight  (IEA)
decreased CD4-positive NK T cell number  (IEA)
decreased circulating alkaline phosphatase level  (IEA)
decreased lymphocyte cell number  (IEA)
decreased memory-marker CD4-positive NK T cell number  (IEA)
decreased NK T cell number  (IEA)
enamel pits  (IAGP)
enlarged heart  (IEA)
enlarged lymph nodes  (IEA)
enlarged stomach  (IEA)
enlarged thymus  (IEA)
increased airway resistance  (IEA)
increased eosinophil cell number  (IEA)
increased lung tissue damping  (IEA)
increased pulmonary respiratory rate  (IEA)
increased tumor incidence  (IAGP)
large mandible  (IAGP)
reduced enamel thickness  (IAGP)
short incisors  (IAGP)
short lower incisors  (IAGP)
short Tomes' process  (IAGP)
short upper incisors  (IAGP)
small seminal vesicle  (IEA)
small spleen  (IEA)
small testis  (IEA)
vertebral transformation  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Molecular cloning and DNA sequence of rat amelogenin and a comparative analysis of mammalian amelogenin protein sequence divergence. Bonass WA, etal., Biochem Biophys Res Commun 1994 Jan 28;198(2):755-63.
2. A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1. Kay GF, etal., Nature 1991 Dec 12;354(6353):486-9.
3. Molecular basis and consequences of a deletion in the amelogenin gene, analyzed by capture PCR. Lagerstrom-Fermer M, etal., Genomics 1993 Jul;17(1):89-92.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Changes in amelogenesis in the rat incisor following short-term hypocalcaemia. Yamaguti PM, etal., Arch Oral Biol. 2005 Feb;50(2):185-8.
Additional References at PubMed
PMID:1427830   PMID:1444889   PMID:1445358   PMID:1463023   PMID:1543904   PMID:1549575   PMID:1675194   PMID:1685478   PMID:2689082   PMID:2737677   PMID:3253061   PMID:4015654  
PMID:7489712   PMID:7554909   PMID:7554933   PMID:7670496   PMID:7684627   PMID:7734452   PMID:7782077   PMID:7806224   PMID:7820782   PMID:7849396   PMID:7896271   PMID:7964557  
PMID:7979162   PMID:8012115   PMID:8026631   PMID:8062146   PMID:8075499   PMID:8179220   PMID:8188251   PMID:8204896   PMID:8392462   PMID:8406441   PMID:8468042   PMID:8535076  
PMID:8552598   PMID:8618899   PMID:8625802   PMID:8672147   PMID:8769659   PMID:8838803   PMID:8884278   PMID:8894143   PMID:8921399   PMID:8921887   PMID:8988368   PMID:9027482  
PMID:9041053   PMID:9062557   PMID:9074935   PMID:9084642   PMID:9199671   PMID:9215685   PMID:9383072   PMID:9714776   PMID:9722947   PMID:9736774   PMID:9878259   PMID:9927592  
PMID:10200911   PMID:10349636   PMID:10675334   PMID:10777661   PMID:10920247   PMID:11042159   PMID:11044393   PMID:11063033   PMID:11063034   PMID:11063035   PMID:11076861   PMID:11217851  
PMID:11406633   PMID:11852235   PMID:11877393   PMID:11879574   PMID:12466851   PMID:12477932   PMID:12489164   PMID:12657653   PMID:12667550   PMID:12851394   PMID:12958690   PMID:14653387  
PMID:14960276   PMID:15525533   PMID:15647828   PMID:15748692   PMID:15972588   PMID:16141072   PMID:16141073   PMID:16172034   PMID:16214432   PMID:16284958   PMID:16293627   PMID:16314533  
PMID:16595692   PMID:16674657   PMID:16674683   PMID:16674684   PMID:16674693   PMID:16707492   PMID:16998127   PMID:17210130   PMID:17335794   PMID:17364666   PMID:17374359   PMID:17384027  
PMID:17449229   PMID:17699513   PMID:17704518   PMID:17708745   PMID:17921454   PMID:18077585   PMID:18346915   PMID:18390542   PMID:18394981   PMID:18515207   PMID:18572160   PMID:18701811  
PMID:18703497   PMID:18714142   PMID:18727043   PMID:18757743   PMID:19086270   PMID:19097165   PMID:19233155   PMID:19251658   PMID:19320717   PMID:19407150   PMID:19462488   PMID:19591819  
PMID:20042744   PMID:20067920   PMID:20304108   PMID:20404336   PMID:20484882   PMID:20487000   PMID:20816801   PMID:20923441   PMID:21034733   PMID:21246660   PMID:21267068   PMID:21285247  
PMID:21402782   PMID:21490069   PMID:21504905   PMID:21540557   PMID:21547453   PMID:21597263   PMID:21677750   PMID:21825148   PMID:21873635   PMID:21984897   PMID:22020075   PMID:22234613  
PMID:22629441   PMID:22648084   PMID:22653892   PMID:22753148   PMID:22759786   PMID:22866057   PMID:23229549   PMID:23477367   PMID:23625374   PMID:23713787   PMID:23747796   PMID:23776616  
PMID:23863486   PMID:23896516   PMID:23975681   PMID:24072097   PMID:24167599   PMID:24362885   PMID:24933156   PMID:25122764   PMID:25376721   PMID:25449314   PMID:25535204   PMID:25792521  
PMID:25885796   PMID:26403673   PMID:26607574   PMID:26709694   PMID:27277399   PMID:27494172   PMID:27660324   PMID:27744011   PMID:27896287   PMID:27896288   PMID:28081373   PMID:28174279  
PMID:28650075   PMID:29273814   PMID:29337060   PMID:29550820   PMID:29604451   PMID:29684584   PMID:29874522   PMID:30286078   PMID:30426815   PMID:30570432   PMID:30963569   PMID:31239344  
PMID:31621902   PMID:31919099   PMID:32243674   PMID:32674056   PMID:32737162   PMID:32760291   PMID:32866472   PMID:33659251   PMID:34012043   PMID:34034544   PMID:34281250   PMID:34487426  
PMID:34630166   PMID:34780561   PMID:35219810   PMID:35271849   PMID:35872015   PMID:36272714   PMID:36403857   PMID:36569763   PMID:36585836   PMID:36702824   PMID:36899896   PMID:37449307  


Genomics

Comparative Map Data
Amelx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X167,959,110 - 167,970,205 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX167,959,110 - 167,970,196 (-)EnsemblGRCm39 Ensembl
GRCm38X169,176,114 - 169,187,209 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX169,176,114 - 169,187,200 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X165,614,046 - 165,625,141 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X164,524,127 - 164,531,314 (-)NCBIMGSCv36mm8
CeleraX152,339,918 - 152,351,218 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.95NCBI
AMELX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,293,413 - 11,309,588 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,293,413 - 11,300,761 (+)EnsemblGRCh38hg38GRCh38
GRCh37X11,311,533 - 11,318,881 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X11,221,454 - 11,228,802 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX15,438,990 - 15,446,338 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX9,091,155 - 9,098,355 (+)NCBIHuRef
CHM1_1X11,342,001 - 11,349,349 (+)NCBICHM1_1
T2T-CHM13v2.0X10,875,912 - 10,892,087 (+)NCBIT2T-CHM13v2.0
Amelx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X28,648,803 - 28,660,099 (+)NCBIGRCr8
mRatBN7.2X25,076,362 - 25,087,660 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,076,362 - 25,087,660 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX26,080,937 - 26,092,217 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X29,502,009 - 29,513,289 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X25,735,122 - 25,746,420 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X26,439,197 - 26,450,495 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX26,439,197 - 26,450,495 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X26,843,989 - 26,855,287 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X45,763,451 - 45,769,374 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X45,816,919 - 45,822,842 (+)NCBI
CeleraX25,496,279 - 25,507,557 (+)NCBICelera
Cytogenetic MapXq13NCBI
Amelx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555441,969,216 - 1,979,063 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555441,974,889 - 1,979,063 (-)NCBIChiLan1.0ChiLan1.0
AMELY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2Y43,791,359 - 44,000,131 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1Y2,926,868 - 3,135,641 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X3,898,819 - 3,930,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X11,214,103 - 11,221,443 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX11,214,103 - 11,221,443 (+)Ensemblpanpan1.1panPan2
AMELX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X7,822,513 - 7,828,692 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX7,822,859 - 7,830,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX7,779,650 - 7,787,144 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X7,776,327 - 7,783,824 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX7,776,321 - 7,783,816 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X7,759,322 - 7,766,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X7,795,375 - 7,802,872 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X7,790,231 - 7,797,728 (+)NCBIUU_Cfam_GSD_1.0
Amelx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,168,483 - 1,174,166 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,169,906 - 1,179,604 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,169,906 - 1,174,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMELX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX8,055,782 - 8,063,449 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X8,055,246 - 8,063,457 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X8,669,948 - 8,677,620 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMELX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X9,927,740 - 9,934,104 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX9,741,594 - 9,745,776 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 EnsemblX9,741,594 - 9,745,776 (+)NCBIChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605611,535,786 - 11,539,980 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amelx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248823,072,313 - 3,082,505 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248823,072,970 - 3,083,832 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Amelx
303 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:195
Interacting mature miRNAs:207
Transcripts:ENSMUST00000066112, ENSMUST00000112118, ENSMUST00000112119, ENSMUST00000112120, ENSMUST00000154923
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401118Pgia39_mproteoglycan induced arthritis 39 (mouse)Not determinedX144474380169476592Mouse
1302000Pgia25_mproteoglycan induced arthritis 2 (mouse)Not determinedX144474380169476592Mouse

Markers in Region
Amel  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXF5UniSTS
cM MapX73.0UniSTS
Amel  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X169,186,293 - 169,186,412UniSTSGRCm38
MGSCv37X165,624,225 - 165,624,344UniSTSGRCm37
CeleraX152,350,302 - 152,350,421UniSTS
Cytogenetic MapXF5UniSTS
cM MapX73.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001081978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001290371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF083091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF294397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI323496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY842498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD773419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D31768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D31769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D83067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU168857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC731591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M10095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S74899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000066112   ⟹   ENSMUSP00000065966
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX167,959,110 - 167,970,196 (-)Ensembl
GRCm38.p6 EnsemblX169,176,114 - 169,187,200 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112118   ⟹   ENSMUSP00000107746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX167,963,018 - 167,970,196 (-)Ensembl
GRCm38.p6 EnsemblX169,180,022 - 169,187,200 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112119   ⟹   ENSMUSP00000107747
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX167,963,018 - 167,970,196 (-)Ensembl
GRCm38.p6 EnsemblX169,180,022 - 169,187,200 (-)Ensembl
RefSeq Acc Id: ENSMUST00000112120   ⟹   ENSMUSP00000107748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX167,963,018 - 167,970,196 (-)Ensembl
GRCm38.p6 EnsemblX169,180,022 - 169,187,200 (-)Ensembl
RefSeq Acc Id: ENSMUST00000154923
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX167,963,018 - 167,970,196 (-)Ensembl
GRCm38.p6 EnsemblX169,180,022 - 169,187,200 (-)Ensembl
RefSeq Acc Id: NM_001081978   ⟹   NP_001075447
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X167,959,110 - 167,970,205 (-)NCBI
GRCm38X169,176,114 - 169,187,209 (-)NCBI
MGSCv37X165,614,046 - 165,625,141 (-)RGD
CeleraX152,339,918 - 152,351,218 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001290371   ⟹   NP_001277300
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X167,963,017 - 167,970,205 (-)NCBI
GRCm38X169,180,021 - 169,187,209 (-)NCBI
CeleraX152,339,918 - 152,351,218 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001415990   ⟹   NP_001402919
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X167,963,017 - 167,970,205 (-)NCBI
RefSeq Acc Id: NM_009666   ⟹   NP_033796
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X167,963,017 - 167,970,205 (-)NCBI
GRCm38X169,180,021 - 169,187,209 (-)NCBI
MGSCv37X165,614,046 - 165,625,141 (-)RGD
CeleraX152,339,918 - 152,351,218 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036161784   ⟹   XP_036017677
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X167,959,116 - 167,970,202 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001075447   ⟸   NM_001081978
- Peptide Label: isoform 1 precursor
- UniProtKB: Q6PCW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_033796   ⟸   NM_009666
- Peptide Label: isoform 2 precursor
- UniProtKB: P63277 (UniProtKB/Swiss-Prot),   R9W2T8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001277300   ⟸   NM_001290371
- Peptide Label: isoform 3 precursor
- UniProtKB: R9W2T8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000065966   ⟸   ENSMUST00000066112
RefSeq Acc Id: ENSMUSP00000107747   ⟸   ENSMUST00000112119
RefSeq Acc Id: ENSMUSP00000107746   ⟸   ENSMUST00000112118
RefSeq Acc Id: ENSMUSP00000107748   ⟸   ENSMUST00000112120
RefSeq Acc Id: XP_036017677   ⟸   XM_036161784
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001402919   ⟸   NM_001415990
- Peptide Label: isoform 4 precursor
- UniProtKB: P70592 (UniProtKB/Swiss-Prot),   P63277 (UniProtKB/Swiss-Prot),   P45559 (UniProtKB/Swiss-Prot),   A2ALX3 (UniProtKB/Swiss-Prot),   A2ALX2 (UniProtKB/Swiss-Prot),   Q61293 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63277-F1-model_v2 AlphaFold P63277 1-210 view protein structure

Promoters
RGD ID:13681872
Promoter ID:EPDNEW_M25085
Type:single initiation site
Name:Amelx_1
Description:Mus musculus amelogenin, X-linked , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X169,187,209 - 169,187,269EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88005 AgrOrtholog
Ensembl Genes ENSMUSG00000031354 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066112 ENTREZGENE
  ENSMUST00000066112.12 UniProtKB/TrEMBL
  ENSMUST00000112118 ENTREZGENE
  ENSMUST00000112118.8 UniProtKB/Swiss-Prot
  ENSMUST00000112119 ENTREZGENE
  ENSMUST00000112119.8 UniProtKB/Swiss-Prot
  ENSMUST00000112120 ENTREZGENE
  ENSMUST00000112120.8 UniProtKB/Swiss-Prot
InterPro Amelogenin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11704 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88005 ENTREZGENE
NCBI Gene 11704 ENTREZGENE
PANTHER AMELOGENIN, Y ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46794 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Amelogenin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Amelx PhenoGen
PRINTS AMELOGENIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Amelogenin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ALX2 ENTREZGENE
  A2ALX3 ENTREZGENE
  AMELX_MOUSE UniProtKB/Swiss-Prot
  B2BY37_MOUSE UniProtKB/TrEMBL
  P45559 ENTREZGENE
  P63277 ENTREZGENE
  P70592 ENTREZGENE
  Q5MAQ9_MOUSE UniProtKB/TrEMBL
  Q61293 ENTREZGENE
  Q6PCW7 ENTREZGENE, UniProtKB/TrEMBL
  R9W2T8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A2ALX2 UniProtKB/Swiss-Prot
  A2ALX3 UniProtKB/Swiss-Prot
  P45559 UniProtKB/Swiss-Prot
  P70592 UniProtKB/Swiss-Prot
  Q61293 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-13 Amelx  amelogenin, X-linked    amelogenin X chromosome  Symbol and/or name change 5135510 APPROVED